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Items: 1 to 50 of 218

1.

Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific γENaC Knockout.

Boscardin E, Perrier R, Sergi C, Maillard MP, Loffing J, Loffing-Cueni D, Koesters R, Rossier BC, Hummler E.

J Am Soc Nephrol. 2018 Mar;29(3):977-990. doi: 10.1681/ASN.2017030345. Epub 2018 Jan 25.

2.

Severe hyperkalemia is rescued by low-potassium diet in renal βENaC-deficient mice.

Boscardin E, Perrier R, Sergi C, Maillard M, Loffing J, Loffing-Cueni D, Koesters R, Rossier BC, Hummler E.

Pflugers Arch. 2017 Oct;469(10):1387-1399. doi: 10.1007/s00424-017-1990-2. Epub 2017 May 31.

3.

The Hypertension Pandemic: An Evolutionary Perspective.

Rossier BC, Bochud M, Devuyst O.

Physiology (Bethesda). 2017 Mar;32(2):112-125. doi: 10.1152/physiol.00026.2016. Review.

4.

Osmoregulation during Long-Term Fasting in Lungfish and Elephant Seal: Old and New Lessons for the Nephrologist.

Rossier BC.

Nephron. 2016;134(1):5-9. doi: 10.1159/000444307. Epub 2016 Feb 23. Review.

5.

Severe Salt-Losing Syndrome and Hyperkalemia Induced by Adult Nephron-Specific Knockout of the Epithelial Sodium Channel α-Subunit.

Perrier R, Boscardin E, Malsure S, Sergi C, Maillard MP, Loffing J, Loffing-Cueni D, Sørensen MV, Koesters R, Rossier BC, Frateschi S, Hummler E.

J Am Soc Nephrol. 2016 Aug;27(8):2309-18. doi: 10.1681/ASN.2015020154. Epub 2015 Dec 23.

6.

Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited.

Rossier BC, Baker ME, Studer RA.

Physiol Rev. 2015 Jan;95(1):297-340. doi: 10.1152/physrev.00011.2014. Review.

7.

[Role of distance learning in the education and the training of the investigator].

Rossier BC, Kraehenbuhl JP, Rossier M.

Med Sci (Paris). 2014 Jun-Jul;30(6-7):603-4. doi: 10.1051/medsci/20143006001. Epub 2014 Jul 11. French. No abstract available.

8.

Epithelial sodium channel (ENaC) and the control of blood pressure.

Rossier BC.

Curr Opin Pharmacol. 2014 Apr;15:33-46. doi: 10.1016/j.coph.2013.11.010. Epub 2013 Dec 12. Review.

PMID:
24721652
9.

Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance.

Malsure S, Wang Q, Charles RP, Sergi C, Perrier R, Christensen BM, Maillard M, Rossier BC, Hummler E.

J Am Soc Nephrol. 2014 Jul;25(7):1453-64. doi: 10.1681/ASN.2013090936. Epub 2014 Jan 30.

10.

Genetic dissection of sodium and potassium transport along the aldosterone-sensitive distal nephron: importance in the control of blood pressure and hypertension.

Rossier BC, Staub O, Hummler E.

FEBS Lett. 2013 Jun 27;587(13):1929-41. doi: 10.1016/j.febslet.2013.05.013. Epub 2013 May 16. Review.

11.

Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism.

Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM.

Am J Physiol Renal Physiol. 2013 Jun 1;304(11):F1390-7. doi: 10.1152/ajprenal.00292.2012. Epub 2013 Mar 20.

12.

The Louis-Jeantet Prize 2013: Michael Stratton, Peter Hegemann and Georg Nagel.

Bushati N, Rossier BC.

EMBO Mol Med. 2013 Feb;5(2):167-8. doi: 10.1002/emmm.201202394. Epub 2013 Jan 22. No abstract available.

13.

The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility.

Suarez PE, Rodriguez EG, Soundararajan R, Mérillat AM, Stehle JC, Rotman S, Roger T, Voirol MJ, Wang J, Gross O, Pétrilli V, Nadra K, Wilson A, Beermann F, Pralong FP, Maillard M, Pearce D, Chrast R, Rossier BC, Hummler E.

Mol Endocrinol. 2012 Jun;26(6):1000-13. doi: 10.1210/me.2011-1249. Epub 2012 May 3.

14.

ENaC inhibition stimulates Cl- secretion in the mouse cortical collecting duct through an NKCC1-dependent mechanism.

Pech V, Thumova M, Kim YH, Agazatian D, Hummler E, Rossier BC, Weinstein AM, Nanami M, Wall SM.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F45-55. doi: 10.1152/ajprenal.00030.2012. Epub 2012 Apr 11.

15.

Rewarding excellence in biomedical research.

Carret C, Rossier BC.

EMBO Mol Med. 2012 Feb;4(2):69-70. doi: 10.1002/emmm.201100196. Epub 2012 Jan 25. No abstract available.

16.

The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.

Pernot E, Terryn S, Cheong SC, Markadieu N, Janas S, Blockmans M, Jacoby M, Pouillon V, Gayral S, Rossier BC, Beauwens R, Erneux C, Devuyst O, Schurmans S.

Pflugers Arch. 2011 Dec;462(6):871-83. doi: 10.1007/s00424-011-1028-0. Epub 2011 Sep 22.

17.

Evolution of the epithelial sodium channel and the sodium pump as limiting factors of aldosterone action on sodium transport.

Studer RA, Person E, Robinson-Rechavi M, Rossier BC.

Physiol Genomics. 2011 Jul 14;43(13):844-54. doi: 10.1152/physiolgenomics.00002.2011. Epub 2011 May 10.

PMID:
21558422
18.

Vasopressin-dependent coupling between sodium transport and water flow in a mouse cortical collecting duct cell line.

Gaeggeler HP, Guillod Y, Loffing-Cueni D, Loffing J, Rossier BC.

Kidney Int. 2011 Apr;79(8):843-52. doi: 10.1038/ki.2010.486. Epub 2010 Dec 22.

19.

alphaENaC-mediated lithium absorption promotes nephrogenic diabetes insipidus.

Christensen BM, Zuber AM, Loffing J, Stehle JC, Deen PM, Rossier BC, Hummler E.

J Am Soc Nephrol. 2011 Feb;22(2):253-61. doi: 10.1681/ASN.2010070734. Epub 2010 Nov 4.

20.

Sodium and potassium balance depends on αENaC expression in connecting tubule.

Christensen BM, Perrier R, Wang Q, Zuber AM, Maillard M, Mordasini D, Malsure S, Ronzaud C, Stehle JC, Rossier BC, Hummler E.

J Am Soc Nephrol. 2010 Nov;21(11):1942-51. doi: 10.1681/ASN.2009101077. Epub 2010 Oct 14.

21.

In vivo nuclear translocation of mineralocorticoid and glucocorticoid receptors in rat kidney: differential effect of corticosteroids along the distal tubule.

Ackermann D, Gresko N, Carrel M, Loffing-Cueni D, Habermehl D, Gomez-Sanchez C, Rossier BC, Loffing J.

Am J Physiol Renal Physiol. 2010 Dec;299(6):F1473-85. doi: 10.1152/ajprenal.00437.2010. Epub 2010 Sep 22.

22.

Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice.

Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC.

J Biol Chem. 2010 Aug 27;285(35):26945-55. doi: 10.1074/jbc.M110.151803. Epub 2010 Jun 21.

23.

Rewarding excellence in biomedical research.

Caldeira S, Rossier BC.

EMBO Mol Med. 2010 Apr;2(4):111-2. doi: 10.1002/emmm.201000069. No abstract available.

24.

Hypertension finds a new rhythm.

Rossier BC.

Nat Med. 2010 Jan;16(1):27-8. doi: 10.1038/nm0110-27. No abstract available.

PMID:
20057418
25.

ENaC-mediated alveolar fluid clearance and lung fluid balance depend on the channel-activating protease 1.

Planès C, Randrianarison NH, Charles RP, Frateschi S, Cluzeaud F, Vuagniaux G, Soler P, Clerici C, Rossier BC, Hummler E.

EMBO Mol Med. 2010 Jan;2(1):26-37. doi: 10.1002/emmm.200900050.

26.

Lithium nephrotoxicity revisited.

Grünfeld JP, Rossier BC.

Nat Rev Nephrol. 2009 May;5(5):270-6. doi: 10.1038/nrneph.2009.43. Review.

PMID:
19384328
27.

Amiloride blocks lithium entry through the sodium channel thereby attenuating the resultant nephrogenic diabetes insipidus.

Kortenoeven ML, Li Y, Shaw S, Gaeggeler HP, Rossier BC, Wetzels JF, Deen PM.

Kidney Int. 2009 Jul;76(1):44-53. doi: 10.1038/ki.2009.91. Epub 2009 Apr 15.

28.

Effects of mineralocorticoid and K+ concentration on K+ secretion and ROMK channel expression in a mouse cortical collecting duct cell line.

Fodstad H, Gonzalez-Rodriguez E, Bron S, Gaeggeler H, Guisan B, Rossier BC, Horisberger JD.

Am J Physiol Renal Physiol. 2009 May;296(5):F966-75. doi: 10.1152/ajprenal.90475.2008. Epub 2009 Mar 18.

29.

cAMP-dependent chloride secretion mediates tubule enlargement and cyst formation by cultured mammalian collecting duct cells.

Montesano R, Ghzili H, Carrozzino F, Rossier BC, Féraille E.

Am J Physiol Renal Physiol. 2009 Feb;296(2):F446-57. doi: 10.1152/ajprenal.90415.2008. Epub 2008 Dec 3.

30.

Activation of the epithelial sodium channel (ENaC) by serine proteases.

Rossier BC, Stutts MJ.

Annu Rev Physiol. 2009;71:361-79. doi: 10.1146/annurev.physiol.010908.163108. Review.

PMID:
18928407
31.

Epithelial sodium channel: mendelian versus essential hypertension.

Rossier BC, Schild L.

Hypertension. 2008 Oct;52(4):595-600. doi: 10.1161/HYPERTENSIONAHA.107.097147. Epub 2008 Aug 18. Review. No abstract available.

PMID:
18711011
32.

NF-kappaB inhibits sodium transport via down-regulation of SGK1 in renal collecting duct principal cells.

de Seigneux S, Leroy V, Ghzili H, Rousselot M, Nielsen S, Rossier BC, Martin PY, Féraille E.

J Biol Chem. 2008 Sep 12;283(37):25671-81. doi: 10.1074/jbc.M803812200. Epub 2008 Jun 27.

33.

Pseudohypoaldosteronisms, report on a 10-patient series.

Belot A, Ranchin B, Fichtner C, Pujo L, Rossier BC, Liutkus A, Morlat C, Nicolino M, Zennaro MC, Cochat P.

Nephrol Dial Transplant. 2008 May;23(5):1636-41. doi: 10.1093/ndt/gfm862.

PMID:
18424465
34.

Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis.

Harris M, Garcia-Caballero A, Stutts MJ, Firsov D, Rossier BC.

J Biol Chem. 2008 Mar 21;283(12):7455-63. doi: 10.1074/jbc.M707399200. Epub 2008 Jan 14.

35.

Low expression of the beta-ENaC subunit impairs lung fluid clearance in the mouse.

Randrianarison N, Clerici C, Ferreira C, Fontayne A, Pradervand S, Fowler-Jaeger N, Hummler E, Rossier BC, Planès C.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L409-16. Epub 2007 Nov 16.

36.

Aldosterone responsiveness of the epithelial sodium channel (ENaC) in colon is increased in a mouse model for Liddle's syndrome.

Bertog M, Cuffe JE, Pradervand S, Hummler E, Hartner A, Porst M, Hilgers KF, Rossier BC, Korbmacher C.

J Physiol. 2008 Jan 15;586(2):459-75. Epub 2007 Nov 15.

37.

Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice.

Zuber AM, Singer D, Penninger JM, Rossier BC, Firsov D.

J Am Soc Nephrol. 2007 Jun;18(6):1672-8. Epub 2007 May 2.

38.

beta-Liddle mutation of the epithelial sodium channel increases alveolar fluid clearance and reduces the severity of hydrostatic pulmonary oedema in mice.

Randrianarison N, Escoubet B, Ferreira C, Fontayne A, Fowler-Jaeger N, Clerici C, Hummler E, Rossier BC, Planès C.

J Physiol. 2007 Jul 15;582(Pt 2):777-88. Epub 2007 Apr 12.

39.

Identification of corticosteroid-regulated genes in cardiomyocytes by serial analysis of gene expression.

Muller O, Pradervand S, Berger S, Centeno G, Milet A, Nicod P, Pedrazzini T, Tronche F, Schütz G, Chien K, Rossier BC, Firsov D.

Genomics. 2007 Mar;89(3):370-7. Epub 2006 Dec 14.

40.

IGF-1 vs insulin: respective roles in modulating sodium transport via the PI-3 kinase/Sgk1 pathway in a cortical collecting duct cell line.

Gonzalez-Rodriguez E, Gaeggeler HP, Rossier BC.

Kidney Int. 2007 Jan;71(2):116-25. Epub 2006 Dec 13.

41.

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.

Harris M, Firsov D, Vuagniaux G, Stutts MJ, Rossier BC.

J Biol Chem. 2007 Jan 5;282(1):58-64. Epub 2006 Nov 7.

42.

Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.

Andreasen D, Vuagniaux G, Fowler-Jaeger N, Hummler E, Rossier BC.

J Am Soc Nephrol. 2006 Apr;17(4):968-76. Epub 2006 Mar 8.

43.

Renal sodium handling: the role of the epithelial sodium channel.

Warnock DG, Rossier BC.

J Am Soc Nephrol. 2005 Nov;16(11):3151-3. Epub 2005 Sep 28. Review. No abstract available.

44.

Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism.

Michlig S, Harris M, Loffing J, Rossier BC, Firsov D.

J Biol Chem. 2005 Nov 18;280(46):38264-70. Epub 2005 Sep 19.

45.

A direct relationship between plasma aldosterone and cardiac L-type Ca2+ current in mice.

Perrier R, Richard S, Sainte-Marie Y, Rossier BC, Jaisser F, Hummler E, Bénitah JP.

J Physiol. 2005 Nov 15;569(Pt 1):153-62. Epub 2005 Sep 15.

46.

The epithelial sodium channel: activation by membrane-bound serine proteases.

Rossier BC.

Proc Am Thorac Soc. 2004;1(1):4-9. Review.

PMID:
16113404
47.

A novel TMPRSS3 missense mutation in a DFNB8/10 family prevents proteolytic activation of the protein.

Wattenhofer M, Sahin-Calapoglu N, Andreasen D, Kalay E, Caylan R, Braillard B, Fowler-Jaeger N, Reymond A, Rossier BC, Karaguzel A, Antonarakis SE.

Hum Genet. 2005 Oct;117(6):528-35. Epub 2005 Jul 14.

PMID:
16021470
48.

Mineralocorticoid versus glucocorticoid receptor occupancy mediating aldosterone-stimulated sodium transport in a novel renal cell line.

Gaeggeler HP, Gonzalez-Rodriguez E, Jaeger NF, Loffing-Cueni D, Norregaard R, Loffing J, Horisberger JD, Rossier BC.

J Am Soc Nephrol. 2005 Apr;16(4):878-91. Epub 2005 Mar 2.

49.

Vasopressin-stimulated CFTR Cl- currents are increased in the renal collecting duct cells of a mouse model of Liddle's syndrome.

Chang CT, Bens M, Hummler E, Boulkroun S, Schild L, Teulon J, Rossier BC, Vandewalle A.

J Physiol. 2005 Jan 1;562(Pt 1):271-84. Epub 2004 Oct 28.

50.

Small proline-rich protein 1A is a gp130 pathway- and stress-inducible cardioprotective protein.

Pradervand S, Yasukawa H, Muller OG, Kjekshus H, Nakamura T, St Amand TR, Yajima T, Matsumura K, Duplain H, Iwatate M, Woodard S, Pedrazzini T, Ross J, Firsov D, Rossier BC, Hoshijima M, Chien KR.

EMBO J. 2004 Nov 10;23(22):4517-25. Epub 2004 Oct 28.

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