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Selective and Concentrated Accretion of SN-38 with a CEACAM5-Targeting Antibody-Drug Conjugate (ADC), Labetuzumab Govitecan (IMMU-130).

Sharkey RM, Govindan SV, Cardillo TM, Donnell J, Xia J, Rossi EA, Chang CH, Goldenberg DM.

Mol Cancer Ther. 2018 Jan;17(1):196-203. doi: 10.1158/1535-7163.MCT-17-0442. Epub 2017 Oct 27.


Phenotypic diversity in autosomal-dominant cone-rod dystrophy elucidated by adaptive optics retinal imaging.

Song H, Rossi EA, Stone E, Latchney L, Williams D, Dubra A, Chung M.

Br J Ophthalmol. 2018 Jan;102(1):136-141. doi: 10.1136/bjophthalmol-2017-310498. Epub 2017 Oct 26.


Combination Therapy with Bispecific Antibodies and PD-1 Blockade Enhances the Antitumor Potency of T Cells.

Chang CH, Wang Y, Li R, Rossi DL, Liu D, Rossi EA, Cardillo TM, Goldenberg DM.

Cancer Res. 2017 Oct 1;77(19):5384-5394. doi: 10.1158/0008-5472.CAN-16-3431. Epub 2017 Aug 17.


Consumption effect of a synbiotic beverage made from soy and yacon extracts containing Bifidobacterium animalis ssp. lactis BB-12 on the intestinal polyamine concentrations in elderly individuals.

Manzoni MSJ, Rossi EA, Pauly-Silveira ND, Pinto RA, Roselino MN, Carlos IZ, Quilles MB, de Abreu Glória MB, Cavallini DCU.

Food Res Int. 2017 Sep;99(Pt 1):495-500. doi: 10.1016/j.foodres.2017.06.005. Epub 2017 Jun 3.


Effect of a probiotic beverage consumption (Enterococcus faecium CRL 183 and Bifidobacterium longum ATCC 15707) in rats with chemically induced colitis.

Celiberto LS, Bedani R, Dejani NN, Ivo de Medeiros A, Sampaio Zuanon JA, Spolidorio LC, Tallarico Adorno MA, Amâncio Varesche MB, Carrilho Galvão F, Valentini SR, Font de Valdez G, Rossi EA, Cavallini DCU.

PLoS One. 2017 Apr 24;12(4):e0175935. doi: 10.1371/journal.pone.0175935. eCollection 2017.


Imaging individual neurons in the retinal ganglion cell layer of the living eye.

Rossi EA, Granger CE, Sharma R, Yang Q, Saito K, Schwarz C, Walters S, Nozato K, Zhang J, Kawakami T, Fischer W, Latchney LR, Hunter JJ, Chung MM, Williams DR.

Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):586-591. doi: 10.1073/pnas.1613445114. Epub 2017 Jan 3.


Probiotic Soy Product Supplemented with Isoflavones Improves the Lipid Profile of Moderately Hypercholesterolemic Men: A Randomized Controlled Trial.

Cavallini DC, Manzoni MS, Bedani R, Roselino MN, Celiberto LS, Vendramini RC, de Valdez G, Abdalla DS, Pinto RA, Rosetto D, Valentini SR, Rossi EA.

Nutrients. 2016 Jan 19;8(1). pii: E52. doi: 10.3390/nu8010052.


Erratum: An adaptive optics imaging system designed for clinical use: publisher's note.

Zhang J, Yang Q, Saito K, Nozato K, Roorda A, Williams DR, Rossi EA.

Biomed Opt Express. 2015 Jul 10;6(8):2864. doi: 10.1364/BOE.6.002864. eCollection 2015 Aug 1.


Cone and rod loss in Stargardt disease revealed by adaptive optics scanning light ophthalmoscopy.

Song H, Rossi EA, Latchney L, Bessette A, Stone E, Hunter JJ, Williams DR, Chung M.

JAMA Ophthalmol. 2015 Oct;133(10):1198-203. doi: 10.1001/jamaophthalmol.2015.2443.


An adaptive optics imaging system designed for clinical use.

Zhang J, Yang Q, Saito K, Nozato K, Williams DR, Rossi EA.

Biomed Opt Express. 2015 May 18;6(6):2120-37. doi: 10.1364/BOE.6.002120. eCollection 2015 Jun 1. Erratum in: Biomed Opt Express. 2015 Aug 1;6(8):2864.


Enhanced Delivery of SN-38 to Human Tumor Xenografts with an Anti-Trop-2-SN-38 Antibody Conjugate (Sacituzumab Govitecan).

Sharkey RM, McBride WJ, Cardillo TM, Govindan SV, Wang Y, Rossi EA, Chang CH, Goldenberg DM.

Clin Cancer Res. 2015 Nov 15;21(22):5131-8. doi: 10.1158/1078-0432.CCR-15-0670. Epub 2015 Jun 23.


Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).

Goldenberg DM, Cardillo TM, Govindan SV, Rossi EA, Sharkey RM.

Oncotarget. 2015 Sep 8;6(26):22496-512.


Probiotics: The scientific evidence in the context of inflammatory bowel disease.

Celiberto LS, Bedani R, Rossi EA, Cavallini DC.

Crit Rev Food Sci Nutr. 2017 Jun 13;57(9):1759-1768. doi: 10.1080/10408398.2014.941457. Review.


Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers.

Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Arrojo R, Liu D, Rossi EA, Chang CH, Goldenberg DM.

Bioconjug Chem. 2015 May 20;26(5):919-31. doi: 10.1021/acs.bioconjchem.5b00223. Epub 2015 May 8.


Calibration-free sinusoidal rectification and uniform retinal irradiance in scanning light ophthalmoscopy.

Yang Q, Yin L, Nozato K, Zhang J, Saito K, Merigan WH, Williams DR, Rossi EA.

Opt Lett. 2015 Jan 1;40(1):85-8. doi: 10.1364/OL.40.000085.


Improving the therapeutic index in cancer therapy by using antibody-drug conjugates designed with a moderately cytotoxic drug.

Govindan SV, Cardillo TM, Rossi EA, Trisal P, McBride WJ, Sharkey RM, Goldenberg DM.

Mol Pharm. 2015 Jun 1;12(6):1836-47. doi: 10.1021/mp5006195. Epub 2014 Nov 25.


Closed-loop optical stabilization and digital image registration in adaptive optics scanning light ophthalmoscopy.

Yang Q, Zhang J, Nozato K, Saito K, Williams DR, Roorda A, Rossi EA.

Biomed Opt Express. 2014 Aug 26;5(9):3174-91. doi: 10.1364/BOE.5.003174. eCollection 2014 Sep 1.


Beneficial effects of fermented vegetal beverages on human gastrointestinal microbial ecosystem in a simulator.

Bianchi F, Rossi EA, Sakamoto IK, Adorno MAT, Van de Wiele T, Sivieri K.

Food Res Int. 2014 Oct;64:43-52. doi: 10.1016/j.foodres.2014.05.072. Epub 2014 Jun 7.


Redirected T-cell killing of solid cancers targeted with an anti-CD3/Trop-2-bispecific antibody is enhanced in combination with interferon-α.

Rossi EA, Rossi DL, Cardillo TM, Chang CH, Goldenberg DM.

Mol Cancer Ther. 2014 Oct;13(10):2341-51. doi: 10.1158/1535-7163.MCT-14-0345. Epub 2014 Jul 22.


Potentially synbiotic fermented beverage with aqueous extracts of quinoa (Chenopodium quinoa Willd) and soy.

Bianchi F, Rossi EA, Gomes RG, Sivieri K.

Food Sci Technol Int. 2015 Sep;21(6):403-15. doi: 10.1177/1082013214540672. Epub 2014 Jun 23.


Long-term reduction in infrared autofluorescence caused by infrared light below the maximum permissible exposure.

Masella BD, Williams DR, Fischer WS, Rossi EA, Hunter JJ.

Invest Ophthalmol Vis Sci. 2014 May 20;55(6):3929-38. doi: 10.1167/iovs.13-12562.


Anti-CD22/CD20 Bispecific antibody with enhanced trogocytosis for treatment of Lupus.

Rossi EA, Chang CH, Goldenberg DM.

PLoS One. 2014 May 19;9(5):e98315. doi: 10.1371/journal.pone.0098315. eCollection 2014.


Optimisation of a sample preparation method for the determination of fumonisin B(1) in rice.

Petrarca MH, Rodrigues MI, Rossi EA, de Sylos CM.

Food Chem. 2014 Sep 1;158:270-7. doi: 10.1016/j.foodchem.2014.02.126. Epub 2014 Mar 6.


Prebiotic effect of fructooligosaccharide in the simulator of the human intestinal microbial ecosystem (SHIME® model).

Sivieri K, Morales ML, Saad SM, Adorno MA, Sakamoto IK, Rossi EA.

J Med Food. 2014 Aug;17(8):894-901. doi: 10.1089/jmf.2013.0092. Epub 2014 Mar 21.


Predictive patient-specific dosimetry and individualized dosing of pretargeted radioimmunotherapy in patients with advanced colorectal cancer.

Schoffelen R, Woliner-van der Weg W, Visser EP, Goldenberg DM, Sharkey RM, McBride WJ, Chang CH, Rossi EA, van der Graaf WT, Oyen WJ, Boerman OC.

Eur J Nucl Med Mol Imaging. 2014 Aug;41(8):1593-602. doi: 10.1007/s00259-014-2742-6. Epub 2014 Mar 19.


Trop-2-targeting tetrakis-ranpirnase has potent antitumor activity against triple-negative breast cancer.

Liu D, Cardillo TM, Wang Y, Rossi EA, Goldenberg DM, Chang CH.

Mol Cancer. 2014 Mar 10;13:53. doi: 10.1186/1476-4598-13-53.


A new class of bispecific antibodies to redirect T cells for cancer immunotherapy.

Rossi DL, Rossi EA, Cardillo TM, Goldenberg DM, Chang CH.

MAbs. 2014 Mar-Apr;6(2):381-91. doi: 10.4161/mabs.27385. Epub 2013 Dec 2.


Anti-CEA antibody fragments labeled with [(18)F]AlF for PET imaging of CEA-expressing tumors.

Lütje S, Franssen GM, Sharkey RM, Laverman P, Rossi EA, Goldenberg DM, Oyen WJ, Boerman OC, McBride WJ.

Bioconjug Chem. 2014 Feb 19;25(2):335-41. doi: 10.1021/bc4004926. Epub 2014 Jan 8.


Automated segmentation of retinal pigment epithelium cells in fluorescence adaptive optics images.

Rangel-Fonseca P, Gómez-Vieyra A, Malacara-Hernández D, Wilson MC, Williams DR, Rossi EA.

J Opt Soc Am A Opt Image Sci Vis. 2013 Dec 1;30(12):2595-604. doi: 10.1364/JOSAA.30.002595.


In vivo imaging of retinal pigment epithelium cells in age related macular degeneration.

Rossi EA, Rangel-Fonseca P, Parkins K, Fischer W, Latchney LR, Folwell MA, Williams DR, Dubra A, Chung MM.

Biomed Opt Express. 2013 Oct 18;4(11):2527-39. doi: 10.1364/BOE.4.002527. eCollection 2013.


Development of an imaging-guided CEA-pretargeted radionuclide treatment of advanced colorectal cancer: first clinical results.

Schoffelen R, Boerman OC, Goldenberg DM, Sharkey RM, van Herpen CM, Franssen GM, McBride WJ, Chang CH, Rossi EA, van der Graaf WT, Oyen WJ.

Br J Cancer. 2013 Aug 20;109(4):934-42. doi: 10.1038/bjc.2013.376. Epub 2013 Jul 16.


Trogocytosis of multiple B-cell surface markers by CD22 targeting with epratuzumab.

Rossi EA, Goldenberg DM, Michel R, Rossi DL, Wallace DJ, Chang CH.

Blood. 2013 Oct 24;122(17):3020-9. doi: 10.1182/blood-2012-12-473744. Epub 2013 Jul 2.


Lactobacillus acidophilus CRL 1014 improved "gut health" in the SHIME reactor.

Sivieri K, Morales ML, Adorno MA, Sakamoto IK, Saad SM, Rossi EA.

BMC Gastroenterol. 2013 Jun 11;13:100. doi: 10.1186/1471-230X-13-100.


Interferon-λ1 linked to a stabilized dimer of Fab potently enhances both antitumor and antiviral activities in targeted cells.

Liu D, Chang CH, Rossi EA, Cardillo TM, Goldenberg DM.

PLoS One. 2013 May 16;8(5):e63940. doi: 10.1371/journal.pone.0063940. Print 2013.


Pretargeted immuno-PET and radioimmunotherapy of prostate cancer with an anti-TROP-2 x anti-HSG bispecific antibody.

van Rij CM, Lütje S, Frielink C, Sharkey RM, Goldenberg DM, Franssen GM, McBride WJ, Rossi EA, Oyen WJ, Boerman OC.

Eur J Nucl Med Mol Imaging. 2013 Sep;40(9):1377-83. doi: 10.1007/s00259-013-2434-7. Epub 2013 May 15.


Incorporation of soybean by-product okara and inulin in a probiotic soy yoghurt: texture profile and sensory acceptance.

Bedani R, Campos MM, Castro IA, Rossi EA, Saad SM.

J Sci Food Agric. 2014 Jan 15;94(1):119-25. doi: 10.1002/jsfa.6212. Epub 2013 Jun 6.


Monoclonal antibodies targeting CD20.

Chang CH, Rossi EA, Goldenberg DM.

MAbs. 2013 May-Jun;5(3):335-6. doi: 10.4161/mabs.24106. Epub 2013 Mar 14. No abstract available.


Visual function and cortical organization in carriers of blue cone monochromacy.

Rossi EA, Achtman RL, Guidon A, Williams DR, Roorda A, Bavelier D, Carroll J.

PLoS One. 2013;8(2):e57956. doi: 10.1371/journal.pone.0057956. Epub 2013 Feb 28.


Optimization of multivalent bispecific antibodies and immunocytokines with improved in vivo properties.

Rossi EA, Chang CH, Cardillo TM, Goldenberg DM.

Bioconjug Chem. 2013 Jan 16;24(1):63-71. doi: 10.1021/bc300488f. Epub 2012 Dec 21.


A potential synbiotic product improves the lipid profile of diabetic rats.

Roselino MN, Pauly-Silveira ND, Cavallini DC, Celiberto LS, Pinto RA, Vendramini RC, Rossi EA.

Lipids Health Dis. 2012 Sep 11;11:114. doi: 10.1186/1476-511X-11-114.


A soy-based product fermented by Enterococcus faecium and Lactobacillus helveticus inhibits the development of murine breast adenocarcinoma.

Kinouchi FL, Maia DC, de Abreu Ribeiro LC, Placeres MC, de Valdez GF, Colombo LL, Rossi EA, Carlos IZ.

Food Chem Toxicol. 2012 Nov;50(11):4144-8. doi: 10.1016/j.fct.2012.08.038. Epub 2012 Aug 25.


Evaluation of a novel hexavalent humanized anti-IGF-1R antibody and its bivalent parental IgG in diverse cancer cell lines.

Chang CH, Wang Y, Trisal P, Li R, Rossi DL, Nair A, Gupta P, Losman M, Cardillo TM, Rossi EA, Goldenberg DM.

PLoS One. 2012;7(8):e44235. doi: 10.1371/journal.pone.0044235. Epub 2012 Aug 31.


A new Tri-Fab bispecific antibody for pretargeting Trop-2-expressing epithelial cancers.

Sharkey RM, van Rij CM, Karacay H, Rossi EA, Frielink C, Regino C, Cardillo TM, McBride WJ, Chang CH, Boerman OC, Goldenberg DM.

J Nucl Med. 2012 Oct;53(10):1625-32. doi: 10.2967/jnumed.112.104364. Epub 2012 Sep 5.


A novel class of anti-HIV agents with multiple copies of enfuvirtide enhances inhibition of viral replication and cellular transmission in vitro.

Chang CH, Hinkula J, Loo M, Falkeborn T, Li R, Cardillo TM, Rossi EA, Goldenberg DM, Wahren B.

PLoS One. 2012;7(7):e41235. doi: 10.1371/journal.pone.0041235. Epub 2012 Jul 23.


Complex and defined biostructures with the dock-and-lock method.

Rossi EA, Goldenberg DM, Chang CH.

Trends Pharmacol Sci. 2012 Sep;33(9):474-81. doi: 10.1016/ Epub 2012 Jun 26.


Pretargeted molecular imaging and radioimmunotherapy.

Goldenberg DM, Chang CH, Rossi EA, J W, McBride, Sharkey RM.

Theranostics. 2012;2(5):523-40. doi: 10.7150/thno.3582. Epub 2012 May 17.


Food restriction and refeeding induces changes in lipid pathways and fat deposition in the adipose and hepatic tissues in rats with diet-induced obesity.

Duarte FO, Sene-Fiorese M, Cheik NC, Maria AS, de Aquino AE Jr, Oishi JC, Rossi EA, Garcia de Oliveira Duarte AC, Dâmaso AR.

Exp Physiol. 2012 Jul;97(7):882-94. doi: 10.1113/expphysiol.2011.064121. Epub 2012 Mar 30.


Pretargeting: taking an alternate route for localizing radionuclides.

Sharkey RM, Chang CH, Rossi EA, McBride WJ, Goldenberg DM.

Tumour Biol. 2012 Jun;33(3):591-600. doi: 10.1007/s13277-012-0367-6. Epub 2012 Mar 7. Review.


Dual-targeting immunotherapy of lymphoma: potent cytotoxicity of anti-CD20/CD74 bispecific antibodies in mantle cell and other lymphomas.

Gupta P, Goldenberg DM, Rossi EA, Cardillo TM, Byrd JC, Muthusamy N, Furman RR, Chang CH.

Blood. 2012 Apr 19;119(16):3767-78. doi: 10.1182/blood-2011-09-381988. Epub 2012 Jan 23.

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