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Items: 1 to 50 of 120

1.

A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System.

Qin Y, Garrison BS, Ma W, Wang R, Jiang A, Li J, Mistry M, Bronson RT, Santoro D, Franco C, Robinton DA, Stevens B, Rossi DJ, Lu C, Springer TA.

Cell. 2018 Jun 28;174(1):156-171.e16. doi: 10.1016/j.cell.2018.05.027. Epub 2018 Jun 14.

PMID:
29909984
2.

The Cerebellar GABAAR System as a Potential Target for Treating Alcohol Use Disorder.

Rossi DJ, Richardson BD.

Handb Exp Pharmacol. 2018 May 8. doi: 10.1007/164_2018_109. [Epub ahead of print]

PMID:
29736774
3.

Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

Mondal N, Dykstra B, Lee J, Ashline DJ, Reinhold VN, Rossi DJ, Sackstein R.

J Biol Chem. 2018 May 11;293(19):7300-7314. doi: 10.1074/jbc.RA117.000775. Epub 2018 Mar 28.

PMID:
29593094
4.

Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage.

Gutierrez-Martinez P, Hogdal L, Nagai M, Kruta M, Singh R, Sarosiek K, Nussenzweig A, Beerman I, Letai A, Rossi DJ.

Nat Cell Biol. 2018 Apr;20(4):413-421. doi: 10.1038/s41556-018-0054-y. Epub 2018 Mar 12.

5.

Intracerebroventricular delivery of hematopoietic progenitors results in rapid and robust engraftment of microglia-like cells.

Capotondo A, Milazzo R, Garcia-Manteiga JM, Cavalca E, Montepeloso A, Garrison BS, Peviani M, Rossi DJ, Biffi A.

Sci Adv. 2017 Dec 6;3(12):e1701211. doi: 10.1126/sciadv.1701211. eCollection 2017 Dec.

6.

Transient Hypoxemia Chronically Disrupts Maturation of Preterm Fetal Ovine Subplate Neuron Arborization and Activity.

McClendon E, Shaver DC, Degener-O'Brien K, Gong X, Nguyen T, Hoerder-Suabedissen A, Molnár Z, Mohr C, Richardson BD, Rossi DJ, Back SA.

J Neurosci. 2017 Dec 6;37(49):11912-11929. doi: 10.1523/JNEUROSCI.2396-17.2017. Epub 2017 Oct 31.

7.

Ethanol withdrawal-induced dysregulation of neurosteroid levels in plasma, cortex, and hippocampus in genetic animal models of high and low withdrawal.

Jensen JP, Nipper MA, Helms ML, Ford MM, Crabbe JC, Rossi DJ, Finn DA.

Psychopharmacology (Berl). 2017 Sep;234(18):2793-2811. doi: 10.1007/s00213-017-4671-0. Epub 2017 Jun 29.

8.

ZFP521 regulates murine hematopoietic stem cell function and facilitates MLL-AF9 leukemogenesis in mouse and human cells.

Garrison BS, Rybak AP, Beerman I, Heesters B, Mercier FE, Scadden DT, Bryder D, Baron R, Rossi DJ.

Blood. 2017 Aug 3;130(5):619-624. doi: 10.1182/blood-2016-09-738591. Epub 2017 Jun 14.

9.

Impact of Roux-en-Y gastric bypass surgery on appetite, alcohol intake behaviors, and midbrain ghrelin signaling in the rat.

Sirohi S, Richardson BD, Lugo JM, Rossi DJ, Davis JF.

Obesity (Silver Spring). 2017 Jul;25(7):1228-1236. doi: 10.1002/oby.21839. Epub 2017 May 12.

10.

mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors.

Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ.

J Clin Invest. 2017 Jun 1;127(6):2433-2437. doi: 10.1172/JCI92030. Epub 2017 May 8.

11.

A Common Origin for B-1a and B-2 Lymphocytes in Clonal Pre- Hematopoietic Stem Cells.

Hadland BK, Varnum-Finney B, Mandal PK, Rossi DJ, Poulos MG, Butler JM, Rafii S, Yoder MC, Yoshimoto M, Bernstein ID.

Stem Cell Reports. 2017 Jun 6;8(6):1563-1572. doi: 10.1016/j.stemcr.2017.04.007. Epub 2017 May 4.

12.

Recreational concentrations of alcohol enhance synaptic inhibition of cerebellar unipolar brush cells via pre- and postsynaptic mechanisms.

Richardson BD, Rossi DJ.

J Neurophysiol. 2017 Jul 1;118(1):267-279. doi: 10.1152/jn.00963.2016. Epub 2017 Apr 5.

13.

Pharmacologically Counteracting a Phenotypic Difference in Cerebellar GABAA Receptor Response to Alcohol Prevents Excessive Alcohol Consumption in a High Alcohol-Consuming Rodent Genotype.

Kaplan JS, Nipper MA, Richardson BD, Jensen J, Helms M, Finn DA, Rossi DJ.

J Neurosci. 2016 Aug 31;36(35):9019-25. doi: 10.1523/JNEUROSCI.0042-16.2016.

14.

Role of a Lateral Orbital Frontal Cortex-Basolateral Amygdala Circuit in Cue-Induced Cocaine-Seeking Behavior.

Arguello AA, Richardson BD, Hall JL, Wang R, Hodges MA, Mitchell MP, Stuber GD, Rossi DJ, Fuchs RA.

Neuropsychopharmacology. 2017 Feb;42(3):727-735. doi: 10.1038/npp.2016.157. Epub 2016 Aug 18.

15.

Alcohol Suppresses Tonic GABAA Receptor Currents in Cerebellar Granule Cells in the Prairie Vole: A Neural Signature of High-Alcohol-Consuming Genotypes.

Kaplan JS, Mohr C, Hostetler CM, Ryabinin AE, Finn DA, Rossi DJ.

Alcohol Clin Exp Res. 2016 Aug;40(8):1617-26. doi: 10.1111/acer.13136. Epub 2016 Jul 18.

16.

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2.

Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, Larsen DM, Li Q, Snow BE, Wakeham A, Haight J, Gorrini C, Bassi C, Thu KL, Murakami K, Elford AR, Ueda T, Straley K, Yen KE, Melino G, Cimmino L, Aifantis I, Levine RL, De Carvalho DD, Lupien M, Rossi DJ, Nolan GP, Cairns RA, Mak TW.

Cancer Cell. 2016 Aug 8;30(2):337-348. doi: 10.1016/j.ccell.2016.05.018. Epub 2016 Jul 14.

17.

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease.

Burberry A, Suzuki N, Wang JY, Moccia R, Mordes DA, Stewart MH, Suzuki-Uematsu S, Ghosh S, Singh A, Merkle FT, Koszka K, Li QZ, Zon L, Rossi DJ, Trowbridge JJ, Notarangelo LD, Eggan K.

Sci Transl Med. 2016 Jul 13;8(347):347ra93. doi: 10.1126/scitranslmed.aaf6038.

18.

DNA Damage and Aging Around the Clock.

Gutierrez-Martinez P, Rossi DJ, Beerman I.

Trends Mol Med. 2016 Aug;22(8):635-637. doi: 10.1016/j.molmed.2016.06.006. Epub 2016 Jun 23.

19.

Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells.

Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R.

Stem Cells. 2016 Oct;34(10):2501-2511. doi: 10.1002/stem.2435. Epub 2016 Jul 17.

20.

Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin.

Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT.

Nat Biotechnol. 2016 Jul;34(7):738-45. doi: 10.1038/nbt.3584. Epub 2016 Jun 6.

21.

Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis.

Säwén P, Lang S, Mandal P, Rossi DJ, Soneji S, Bryder D.

Cell Rep. 2016 Mar 29;14(12):2809-18. doi: 10.1016/j.celrep.2016.02.073. Epub 2016 Mar 17.

22.

Two new routes to make blood: Hematopoietic specification from pluripotent cell lines versus reprogramming of somatic cells.

Singbrant S, van Galen P, Lucas D, Challen G, Rossi DJ, Daley GQ.

Exp Hematol. 2015 Sep;43(9):756-9. doi: 10.1016/j.exphem.2015.05.007. Epub 2015 Jul 2. Review.

PMID:
26143581
23.

Progress and obstacles towards generating hematopoietic stem cells from pluripotent stem cells.

Lee J, Dykstra B, Sackstein R, Rossi DJ.

Curr Opin Hematol. 2015 Jul;22(4):317-23. doi: 10.1097/MOH.0000000000000147. Review.

24.

Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease.

Beerman I, Rossi DJ.

Cell Stem Cell. 2015 Jun 4;16(6):613-25. doi: 10.1016/j.stem.2015.05.009. Review.

25.

Transcription factor-mediated reprogramming toward hematopoietic stem cells.

Ebina W, Rossi DJ.

EMBO J. 2015 Mar 12;34(6):694-709. doi: 10.15252/embj.201490804. Epub 2015 Feb 20. Review.

26.

The histone demethylase Jarid1b is required for hematopoietic stem cell self-renewal in mice.

Stewart MH, Albert M, Sroczynska P, Cruickshank VA, Guo Y, Rossi DJ, Helin K, Enver T.

Blood. 2015 Mar 26;125(13):2075-8. doi: 10.1182/blood-2014-08-596734. Epub 2015 Feb 5.

27.

Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9.

Mandal PK, Ferreira LM, Collins R, Meissner TB, Boutwell CL, Friesen M, Vrbanac V, Garrison BS, Stortchevoi A, Bryder D, Musunuru K, Brand H, Tager AM, Allen TM, Talkowski ME, Rossi DJ, Cowan CA.

Cell Stem Cell. 2014 Nov 6;15(5):643-52. doi: 10.1016/j.stem.2014.10.004. Epub 2014 Nov 6.

28.

Genome editing for human gene therapy.

Meissner TB, Mandal PK, Ferreira LM, Rossi DJ, Cowan CA.

Methods Enzymol. 2014;546:273-95. doi: 10.1016/B978-0-12-801185-0.00013-1.

PMID:
25398345
29.

Growth hormone receptor signaling is dispensable for HSC function and aging.

Stewart MH, Gutierrez-Martinez P, Beerman I, Garrison B, Gallagher EJ, LeRoith D, Rossi DJ.

Blood. 2014 Nov 13;124(20):3076-80. doi: 10.1182/blood-2014-05-575308. Epub 2014 Oct 1.

30.

Epigenetic regulation of hematopoietic stem cell aging.

Beerman I, Rossi DJ.

Exp Cell Res. 2014 Dec 10;329(2):192-9. doi: 10.1016/j.yexcr.2014.09.013. Epub 2014 Sep 28. Review.

31.

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier.

Santos MA, Faryabi RB, Ergen AV, Day AM, Malhowski A, Canela A, Onozawa M, Lee JE, Callen E, Gutierrez-Martinez P, Chen HT, Wong N, Finkel N, Deshpande A, Sharrow S, Rossi DJ, Ito K, Ge K, Aplan PD, Armstrong SA, Nussenzweig A.

Nature. 2014 Oct 2;514(7520):107-11. doi: 10.1038/nature13483. Epub 2014 Jul 27.

32.

Fgd5 identifies hematopoietic stem cells in the murine bone marrow.

Gazit R, Mandal PK, Ebina W, Ben-Zvi A, Nombela-Arrieta C, Silberstein LE, Rossi DJ.

J Exp Med. 2014 Jun 30;211(7):1315-31. doi: 10.1084/jem.20130428. Epub 2014 Jun 23.

33.

Loss of P2Y₁₄ results in an arresting response to hematological stress.

Garrison BS, Rossi DJ.

J Clin Invest. 2014 Jul;124(7):2846-8. doi: 10.1172/JCI76626. Epub 2014 Jun 17.

34.

Quantification of ten neuroactive steroids in plasma in Withdrawal Seizure-Prone and -Resistant mice during chronic ethanol withdrawal.

Snelling C, Tanchuck-Nipper MA, Ford MM, Jensen JP, Cozzoli DK, Ramaker MJ, Helms M, Crabbe JC, Rossi DJ, Finn DA.

Psychopharmacology (Berl). 2014 Sep;231(17):3401-14. doi: 10.1007/s00213-014-3618-y. Epub 2014 May 29.

35.

Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle.

Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ.

Cell Stem Cell. 2014 Jul 3;15(1):37-50. doi: 10.1016/j.stem.2014.04.016. Epub 2014 May 8.

36.

Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors.

Riddell J, Gazit R, Garrison BS, Guo G, Saadatpour A, Mandal PK, Ebina W, Volchkov P, Yuan GC, Orkin SH, Rossi DJ.

Cell. 2014 Apr 24;157(3):549-64. doi: 10.1016/j.cell.2014.04.006. Erratum in: Cell. 2014 Jul 3;158(1):226.

37.

Prenatal cerebral ischemia triggers dysmaturation of caudate projection neurons.

McClendon E, Chen K, Gong X, Sharifnia E, Hagen M, Cai V, Shaver DC, Riddle A, Dean JM, Gunn AJ, Mohr C, Kaplan JS, Rossi DJ, Kroenke CD, Hohimer AR, Back SA.

Ann Neurol. 2014 Apr;75(4):508-24. doi: 10.1002/ana.24100. Epub 2014 Mar 13.

38.

Primate cerebellar granule cells exhibit a tonic GABAAR conductance that is not affected by alcohol: a possible cellular substrate of the low level of response phenotype.

Mohr C, Kolotushkina O, Kaplan JS, Welsh J, Daunais JB, Grant KA, Rossi DJ.

Front Neural Circuits. 2013 Nov 26;7:189. doi: 10.3389/fncir.2013.00189. eCollection 2013.

39.

Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells.

Gazit R, Garrison BS, Rao TN, Shay T, Costello J, Ericson J, Kim F, Collins JJ, Regev A, Wagers AJ, Rossi DJ; Immunological Genome Project Consortium.

Stem Cell Reports. 2013 Aug 15;1(3):266-80. doi: 10.1016/j.stemcr.2013.07.004. eCollection 2013.

40.

Human iPSC-based modeling of late-onset disease via progerin-induced aging.

Miller JD, Ganat YM, Kishinevsky S, Bowman RL, Liu B, Tu EY, Mandal PK, Vera E, Shim JW, Kriks S, Taldone T, Fusaki N, Tomishima MJ, Krainc D, Milner TA, Rossi DJ, Studer L.

Cell Stem Cell. 2013 Dec 5;13(6):691-705. doi: 10.1016/j.stem.2013.11.006.

41.

Opposite actions of alcohol on tonic GABA(A) receptor currents mediated by nNOS and PKC activity.

Kaplan JS, Mohr C, Rossi DJ.

Nat Neurosci. 2013 Dec;16(12):1783-93. doi: 10.1038/nn.3559. Epub 2013 Oct 27.

42.

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.

Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR.

Nat Biotechnol. 2013 Oct;31(10):898-907. doi: 10.1038/nbt.2682. Epub 2013 Sep 8.

43.

The transcriptional landscape of αβ T cell differentiation.

Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C; Immunological Genome Consortium, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Nageswara Rao T, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S.

Nat Immunol. 2013 Jun;14(6):619-32. doi: 10.1038/ni.2590. Epub 2013 May 5.

44.

Identification of transcriptional regulators in the mouse immune system.

Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D; Immunological Genome Project Consortium, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemarte-Pelletier A, Malhotra D, Turley S.

Nat Immunol. 2013 Jun;14(6):633-43. doi: 10.1038/ni.2587. Epub 2013 Apr 28.

45.

Reprogramming human fibroblasts to pluripotency using modified mRNA.

Mandal PK, Rossi DJ.

Nat Protoc. 2013 Mar;8(3):568-82. doi: 10.1038/nprot.2013.019. Epub 2013 Feb 21.

PMID:
23429718
46.

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, Rossi DJ.

Cell Stem Cell. 2013 Apr 4;12(4):413-25. doi: 10.1016/j.stem.2013.01.017. Epub 2013 Feb 14.

47.

Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML.

Vo TT, Ryan J, Carrasco R, Neuberg D, Rossi DJ, Stone RM, Deangelo DJ, Frattini MG, Letai A.

Cell. 2012 Oct 12;151(2):344-55. doi: 10.1016/j.cell.2012.08.038.

48.

DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.

Bock C, Beerman I, Lien WH, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, Meissner A.

Mol Cell. 2012 Aug 24;47(4):633-47. doi: 10.1016/j.molcel.2012.06.019. Epub 2012 Jul 26.

49.

Gene Expression Commons: an open platform for absolute gene expression profiling.

Seita J, Sahoo D, Rossi DJ, Bhattacharya D, Serwold T, Inlay MA, Ehrlich LI, Fathman JW, Dill DL, Weissman IL.

PLoS One. 2012;7(7):e40321. doi: 10.1371/journal.pone.0040321. Epub 2012 Jul 18.

50.

Neurosteroid influences on sensitivity to ethanol.

Helms CM, Rossi DJ, Grant KA.

Front Endocrinol (Lausanne). 2012 Jan 31;3:10. doi: 10.3389/fendo.2012.00010. eCollection 2012.

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