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Molecular characterisation of multidrug-resistant Mycobacterium tuberculosis isolates from a high-burden tuberculosis state in Brazil.

Salvato RS, Schiefelbein S, Barcellos RB, Praetzel BM, Anusca IS, Esteves LS, Halon ML, Unis G, Dias CF, Miranda SS, de Almeida IN, de Assis Figueredo LJ, Silva EC, Kritski AL, Dalla Costa ER, Rossetti MLR.

Epidemiol Infect. 2019 Jan;147:e216. doi: 10.1017/S0950268819001006.


Disruptions to the limb muscle core molecular clock coincide with changes in mitochondrial quality control following androgen depletion.

Rossetti ML, Esser KA, Lee C, Tomko RJ Jr, Eroshkin AM, Gordon BS.

Am J Physiol Endocrinol Metab. 2019 Oct 1;317(4):E631-E645. doi: 10.1152/ajpendo.00177.2019. Epub 2019 Jul 30.


Arrdc2 and Arrdc3 elicit divergent changes in gene expression in skeletal muscle following anabolic and catabolic stimuli.

Gordon BS, Rossetti ML, Eroshkin AM.

Physiol Genomics. 2019 Jun 1;51(6):208-217. doi: 10.1152/physiolgenomics.00007.2019. Epub 2019 Apr 19.


Geospatial intelligence and health analitycs: Its application and utility in a city with high tuberculosis incidence in Brazil.

Gehlen M, Nicola MRC, Costa ERD, Cabral VK, de Quadros ELL, Chaves CO, Lahm RA, Nicolella ADR, Rossetti MLR, Silva DR.

J Infect Public Health. 2019 Sep - Oct;12(5):681-689. doi: 10.1016/j.jiph.2019.03.012. Epub 2019 Apr 5.


Hormonal regulation of core clock gene expression in skeletal muscle following acute aerobic exercise.

Saracino PG, Rossetti ML, Steiner JL, Gordon BS.

Biochem Biophys Res Commun. 2019 Jan 15;508(3):871-876. doi: 10.1016/j.bbrc.2018.12.034. Epub 2018 Dec 8.


Androgens induce growth of the limb skeletal muscles in a rapamycin-insensitive manner.

Rossetti ML, Fukuda DH, Gordon BS.

Am J Physiol Regul Integr Comp Physiol. 2018 Oct 1;315(4):R721-R729. doi: 10.1152/ajpregu.00029.2018. Epub 2018 Jun 13.


Genetic diversity of Mycobacterium tuberculosis isoniazid monoresistant and multidrug-resistant in Rio Grande do Sul, a tuberculosis high-burden state in Brazil.

Esteves LS, Dalla Costa ER, Vasconcellos SEG, Vargas A, Ferreira Junior SLM, Halon ML, Ribeiro MO, Rodenbusch R, Gomes HM, Suffys PN, Rossetti MLR.

Tuberculosis (Edinb). 2018 May;110:36-43. doi: 10.1016/ Epub 2018 Mar 1.


A high prevalence of human papillomavirus 16 and 18 co-infections in cervical biopsies from southern Brazil.

Jesus SP, Costa ACMD, Barcellos RB, Medeiros RM, Silva CMDD, Rossetti ML.

Braz J Microbiol. 2018 Nov;49 Suppl 1:220-223. doi: 10.1016/j.bjm.2018.04.003. Epub 2018 Apr 24.


Clinical and molecular profile of newborns with confirmed or suspicious congenital adrenal hyperplasia detected after a public screening program implementation.

Kopacek C, Prado MJ, da Silva CMD, de Castro SM, Beltrão LA, Vargas PR, Grandi T, Rossetti MLR, Spritzer PM.

J Pediatr (Rio J). 2019 May - Jun;95(3):282-290. doi: 10.1016/j.jped.2018.03.003. Epub 2018 Apr 30.


Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.

Perdigão J, Silva C, Diniz J, Pereira C, Machado D, Ramos J, Silva H, Abilleira F, Brum C, Reis AJ, Macedo M, Scaini JL, Silva AB, Esteves L, Macedo R, Maltez F, Clemente S, Coelho E, Viegas S, Rabna P, Rodrigues A, Taveira N, Jordao L, Kritski A, Lapa E Silva JR, Mokrousov I, Couvin D, Rastogi N, Couto I, Pain A, McNerney R, Clark TG, von Groll A, Dalla-Costa ER, Rossetti ML, Silva PEA, Viveiros M, Portugal I.

Infect Genet Evol. 2019 Aug;72:44-58. doi: 10.1016/j.meegid.2018.03.011. Epub 2018 Mar 17.


Molecular Method Confirms Canine Leishmania Infection Detected by Serological Methods in Non-Endemic Area of Brazil.

Riboldi E, Carvalho F, Romão PRT, Barcellos RB, Bello GL, Ramos RR, de Oliveira RT, Júnior JPA, Rossetti ML, Dallegrave E.

Korean J Parasitol. 2018 Feb;56(1):11-19. doi: 10.3347/kjp.2018.56.1.11. Epub 2018 Feb 28.


Canine visceral leishmaniasis diagnosis: a comparative performance of serological and molecular tests in symptomatic and asymptomatic dogs.

de Carvalho FLN, Riboldi EO, Bello GL, Ramos RR, Barcellos RB, Gehlen M, Halon ML, Romão PRT, Dallegrave E, Rossetti MLR.

Epidemiol Infect. 2018 Apr;146(5):571-576. doi: 10.1017/S0950268818000225. Epub 2018 Feb 26.


Increased mitochondrial turnover in the skeletal muscle of fasted, castrated mice is related to the magnitude of autophagy activation and muscle atrophy.

Rossetti ML, Steiner JL, Gordon BS.

Mol Cell Endocrinol. 2018 Sep 15;473:178-185. doi: 10.1016/j.mce.2018.01.017. Epub 2018 Feb 1.


Polymerase chain reaction test in induced sputum of patients with pulmonary tuberculosis.

Paiva VDS, Staub FL, Valentini DF Jr, Barcellos RB, Schmid KB, Costa ERD, Rossetti MLR, Dalcin PTR, Silva DR.

Clin Respir J. 2018 May;12(5):1865-1871. doi: 10.1111/crj.12749. Epub 2018 Jan 1.


REDD1 induction regulates the skeletal muscle gene expression signature following acute aerobic exercise.

Gordon BS, Steiner JL, Rossetti ML, Qiao S, Ellisen LW, Govindarajan SS, Eroshkin AM, Williamson DL, Coen PM.

Am J Physiol Endocrinol Metab. 2017 Dec 1;313(6):E737-E747. doi: 10.1152/ajpendo.00120.2017. Epub 2017 Sep 12.


Development of CYP21A2 Genotyping Assay for the Diagnosis of Congenital Adrenal Hyperplasia.

Prado MJ, de Castro SM, Kopacek C, de Mello MP, Rispoli T, Grandi T, da Silva CMD, Rossetti MLR.

Mol Diagn Ther. 2017 Dec;21(6):663-675. doi: 10.1007/s40291-017-0296-6.


The Effects of Multiple Sets of Squats and Jump Squats on Mechanical Variables.

Rossetti ML, Munford SN, Snyder BW, Davis SE, Moir GL.

J Strength Cond Res. 2017 Jul 28. doi: 10.1519/JSC.0000000000002009. [Epub ahead of print]


Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.

Santos PFGD, Costa ERD, Ramalho DM, Rossetti ML, Barcellos RB, Nunes LS, Esteves LS, Rodenbusch R, Anthony RM, Bergval I, Sengstake S, Viveiros M, Kritski A, Oliveira MM.

Mem Inst Oswaldo Cruz. 2017 Jun;112(6):396-403. doi: 10.1590/0074-02760160376.


The role of androgens in the regulation of muscle oxidative capacity following aerobic exercise training.

Rossetti ML, Gordon BS.

Appl Physiol Nutr Metab. 2017 Sep;42(9):1001-1007. doi: 10.1139/apnm-2017-0230. Epub 2017 Jun 1.


Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis.

Machado D, Coelho TS, Perdigão J, Pereira C, Couto I, Portugal I, Maschmann RA, Ramos DF, von Groll A, Rossetti MLR, Silva PA, Viveiros M.

Front Microbiol. 2017 Apr 27;8:711. doi: 10.3389/fmicb.2017.00711. eCollection 2017.


Prevalence of hepatitis C virus and human immunodeficiency virus in a group of patients newly diagnosed with active tuberculosis in Porto Alegre, Southern Brazil.

Costi C, Grandi T, Halon ML, Silva MS, Silva CM, Gregianini TS, Possuelo LG, Jarczewski CA, Niel C, Rossetti ML.

Mem Inst Oswaldo Cruz. 2017 Apr;112(4):255-259. doi: 10.1590/0074-02760160352.


Androgen-mediated regulation of skeletal muscle protein balance.

Rossetti ML, Steiner JL, Gordon BS.

Mol Cell Endocrinol. 2017 May 15;447:35-44. doi: 10.1016/j.mce.2017.02.031. Epub 2017 Feb 22. Review.


Performance of a molecular assay to detect Mycobacterium tuberculosis complex DNA in clinical specimens: multicenter study in Brazil.

Verza M, Schmid KB, Barcellos RB, Linck N, Bello GL, Scapin D, Sperhacke RD, Silva MS, Wollheim C, Rivero MG, Kritski AL, Rezende L Jr, Oliveira MM, Costa ER, Rossetti ML.

Mem Inst Oswaldo Cruz. 2017 Feb;112(2):94-99. doi: 10.1590/0074-02760160196.


Castration alters protein balance after high-frequency muscle contraction.

Steiner JL, Fukuda DH, Rossetti ML, Hoffman JR, Gordon BS.

J Appl Physiol (1985). 2017 Feb 1;122(2):264-272. doi: 10.1152/japplphysiol.00740.2016. Epub 2016 Dec 1.


First insight into the molecular epidemiology of Mycobacterium tuberculosis in Santa Catarina, southern Brazil.

Nogueira CL, Prim RI, Senna SG, Rovaris DB, Maurici R, Rossetti ML, Couvin D, Rastogi N, Bazzo ML.

Tuberculosis (Edinb). 2016 Mar;97:57-64. doi: 10.1016/ Epub 2016 Jan 7.


Association between cytokine gene polymorphisms and outcome of hepatitis B virus infection in southern Brazil.

Gusatti Cde S, Costi C, de Medeiros RM, Halon ML, Grandi T, Medeiros AF, da Silva CM, Rodenbusch R, Silva MS, Niel C, Rossetti ML.

J Med Virol. 2016 Oct;88(10):1759-66. doi: 10.1002/jmv.24518. Epub 2016 Mar 22.


Association of human papillomavirus and Chlamydia trachomatis with intraepithelial alterations in cervix samples.

Wohlmeister D, Vianna DR, Helfer VE, Gimenes F, Consolaro ME, Barcellos RB, Rossetti ML, Calil LN, Buffon A, Pilger DA.

Mem Inst Oswaldo Cruz. 2016 Feb;111(2):106-13. doi: 10.1590/0074-02760150330. Epub 2016 Feb 2.


Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population.

Milano M, Moraes MO, Rodenbusch R, Carvalho CX, Delcroix M, Mousquer G, Laux da Costa L, Unis G, Dalla Costa ER, Rossetti ML.

PLoS One. 2016 Feb 3;11(2):e0147814. doi: 10.1371/journal.pone.0147814. eCollection 2016.


Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil.

Dalla Costa ER, Vasconcelos SE, Esteves LS, Gomes HM, Gomes LL, da Silva PA, Perdigão J, Portugal I, Viveiros M, McNerney R, Pain A, Clark TG, Rastogi N, Unis G, Rossetti ML, Suffys PN.

J Clin Microbiol. 2015 Dec;53(12):3805-11.


Hepatitis B Virus Genotype D Isolates Circulating in Chapecó, Southern Brazil, Originate from Italy.

Gusatti CS, Costi C, Halon ML, Grandi T, Medeiros AF, Silva CM, Gomes SA, Silva MS, Niel C, Rossetti ML.

PLoS One. 2015 Aug 14;10(8):e0135816. doi: 10.1371/journal.pone.0135816. eCollection 2015.


A real-time PCR signature to discriminate between tuberculosis and other pulmonary diseases.

Laux da Costa L, Delcroix M, Dalla Costa ER, Prestes IV, Milano M, Francis SS, Unis G, Silva DR, Riley LW, Rossetti ML.

Tuberculosis (Edinb). 2015 Jul;95(4):421-5. doi: 10.1016/ Epub 2015 May 14.


Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil.

Coelho T, Machado D, Couto I, Maschmann R, Ramos D, von Groll A, Rossetti ML, Silva PA, Viveiros M.

Front Microbiol. 2015 Apr 28;6:330. doi: 10.3389/fmicb.2015.00330. eCollection 2015.


Smear plus Detect-TB for a sensitive diagnosis of pulmonary tuberculosis: a cost-effectiveness analysis in an incarcerated population.

Schmid KB, Scherer L, Barcellos RB, Kuhleis D, Prestes IV, Steffen RE, Dalla Costa ER, Rossetti ML.

BMC Infect Dis. 2014 Dec 16;14:678. doi: 10.1186/s12879-014-0678-x.


Use of conventional PCR and smear microscopy to diagnose pulmonary tuberculosis in the Amazonian rainforest area.

Carniel F, Dalla Costa ER, Lima-Bello G, Martins C, Scherer LC, Rossetti ML.

Braz J Med Biol Res. 2014 Dec;47(12):1016-20. Epub 2014 Sep 16.


Tuberculosis recurrence in a high incidence setting for HIV and tuberculosis in Brazil.

Unis G, Ribeiro AW, Esteves LS, Spies FS, Picon PD, Dalla Costa ER, Rossetti ML.

BMC Infect Dis. 2014 Oct 24;14:548. doi: 10.1186/s12879-014-0548-6.


Evaluation of four molecular methods for the diagnosis of tuberculosis in pulmonary and blood samples from immunocompromised patients.

Lyra JM, Maruza M, Verza M, Carneiro MM, Albuquerque Mde F, Rossetti ML, Ximenes R, Braga MC, Lucena-Silva N.

Mem Inst Oswaldo Cruz. 2014 Sep;109(6):805-13. Epub 2014 Aug 29.


Association between cervical lesion grade and micronucleus frequency in the Papanicolaou test.

Bueno CT, Dornelles da Silva CM, Barcellos RB, da Silva J, Dos Santos CR, Menezes JE, Menezes HS, Rossetti ML.

Genet Mol Biol. 2014 Sep;37(3):496-9.


Association between human papillomavirus (HPV) DNA and micronuclei in normal cervical cytology.

Cassel AP, Barcellos RB, da Silva CM, de Matos Almeida SE, Rossetti ML.

Genet Mol Biol. 2014 Jun;37(2):360-3.


Polymorphisms in CYP2E1, GSTM1 and GSTT1 and anti-tuberculosis drug-induced hepatotoxicity.

Brito TC, Possuelo LG, Valim ARM, Todendi PF, Ribeiro AW, Gregianini TS, Jarczewski CA, Hutz MH, Rossetti MLR, Zaha A.

An Acad Bras Cienc. 2014 Jun;86(2):855-865.


In house reverse membrane hybridisation assay versus GenoType MTBDRplus and their performance to detect mutations in the genes rpoB, katG and inhA.

Ferreira Junior SL, Dalla Costa ER, Santos PG, Gomes HM, Silva MS, Esteves LS, Oliveira MM, Maschmann Rde A, Kritski AL, Suffys PN, Rossetti ML.

Mem Inst Oswaldo Cruz. 2014 Jun;109(3):307-14. Epub 2014 May 7.


Tumour necrosis factor -308 and -238 promoter polymorphisms are predictors of a null virological response in the treatment of Brazilian hepatitis C patients.

Grandi T, Silva CM, Amaral KM, Picon PD, Costi C, Fré NN, Fiegenbaum M, Gregianini TS, Niel C, Rossetti ML.

Mem Inst Oswaldo Cruz. 2014 Jun;109(3):345-51.


Comparison of urine and self-collected vaginal samples for detecting human papillomavirus DNA in pregnant women.

Franciscatto LG, Silva CM, Barcellos RB, Angeli S, Silva MS, Almeida SE, Rossetti ML.

Int J Gynaecol Obstet. 2014 Apr;125(1):69-72. doi: 10.1016/j.ijgo.2013.09.031. Epub 2014 Jan 2.


Evaluation of six different DNA extraction methods for detection of Mycobacterium tuberculosis by means of PCR-IS6110: preliminary study.

De Almeida IN, Da Silva Carvalho W, Rossetti ML, Costa ER, De Miranda SS.

BMC Res Notes. 2013 Dec 28;6:561. doi: 10.1186/1756-0500-6-561.


Performance of the GenoType MTBDRplus assay directly on sputum specimens from Brazilian patients with tuberculosis treatment failure or relapse.

Maschmann Rde A, Sá Spies F, Nunes Lde S, Ribeiro AW, Machado TR, Zaha A, Rossetti ML.

J Clin Microbiol. 2013 May;51(5):1606-8. doi: 10.1128/JCM.00364-13. Epub 2013 Mar 6.


Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene.

Grandi T, da Silva CM, Amaral KM, Picon PD, Costi C, da Fré NN, Fiegenbaum M, Niel C, Rossetti ML.

Mem Inst Oswaldo Cruz. 2013 Feb;108(1):48-53.


Mycobacterium tuberculosis of the RDRio genotype is the predominant cause of tuberculosis and associated with multidrug resistance in Porto Alegre City, South Brazil.

Dalla Costa ER, Lazzarini LC, Perizzolo PF, Díaz CA, Spies FS, Costa LL, Ribeiro AW, Barroco C, Schuh SJ, da Silva Pereira MA, Dias CF, Gomes HM, Unis G, Zaha A, Almeida da Silva PE, Suffys PN, Rossetti ML.

J Clin Microbiol. 2013 Apr;51(4):1071-7. doi: 10.1128/JCM.01511-12. Epub 2013 Jan 16.


Biological cost in Mycobacterium tuberculosis with mutations in the rpsL, rrs, rpoB, and katG genes.

Spies FS, von Groll A, Ribeiro AW, Ramos DF, Ribeiro MO, Dalla Costa ER, Martin A, Palomino JC, Rossetti ML, Zaha A, da Silva PE.

Tuberculosis (Edinb). 2013 Mar;93(2):150-4. doi: 10.1016/ Epub 2012 Dec 29.


Tuberculosis in a southern Brazilian prison.

Kuhleis D, Ribeiro AW, Costa ER, Cafrune PI, Schmid KB, Costa LL, Ribeiro MO, Zaha A, Rossetti ML.

Mem Inst Oswaldo Cruz. 2012 Nov;107(7):909-15.


The high prevalence of Torque teno virus DNA in blood donors and haemodialysis patients in southern Brazil.

Massaú A, Martins C, Nachtigal GC, Araújo AB, Rossetti ML, Niel C, da Silva CM.

Mem Inst Oswaldo Cruz. 2012 Aug;107(5):684-6.


Use of FTA elute card impregnated with cervicovaginal sample directly into the amplification reaction increases the detection of human papillomavirus DNA.

Santos CR, Franciscatto LG, Barcellos RB, Almeida SE, Rossetti ML.

Braz J Microbiol. 2012 Jan;43(1):389-92. doi: 10.1590/S1517-838220120001000047. Epub 2012 Jun 1.

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