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Items: 1 to 50 of 69

1.

The role of Syk in peripheral T cells.

Park JE, Majumdar S, Brand DD, Rosloniec EF, Yi AK, Stuart JM, Kang AH, Myers LK.

Clin Immunol. 2018 Jul;192:50-57. doi: 10.1016/j.clim.2018.04.007. Epub 2018 Apr 16.

2.

Shared epitope-aryl hydrocarbon receptor crosstalk underlies the mechanism of gene-environment interaction in autoimmune arthritis.

Fu J, Nogueira SV, Drongelen VV, Coit P, Ling S, Rosloniec EF, Sawalha AH, Holoshitz J.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):4755-4760. doi: 10.1073/pnas.1722124115. Epub 2018 Apr 16.

3.

The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis.

Kim S, Easterling ER, Price LC, Smith SL, Coligan JE, Park JE, Brand DD, Rosloniec EF, Stuart JM, Kang AH, Myers LK.

J Immunol. 2017 Oct 15;199(8):2692-2700. doi: 10.4049/jimmunol.1700271. Epub 2017 Sep 8.

4.

Bone loss and aggravated autoimmune arthritis in HLA-DRĪ²1-bearing humanized mice following oral challenge with Porphyromonas gingivalis.

Sandal I, Karydis A, Luo J, Prislovsky A, Whittington KB, Rosloniec EF, Dong C, Novack DV, Mydel P, Zheng SG, Radic MZ, Brand DD.

Arthritis Res Ther. 2016 Oct 26;18(1):249.

5.

Arthritogenic peptide binding to DRB1*01 alleles correlates with susceptibility to rheumatoid arthritis.

Roark CL, Anderson KM, Aubrey MT, Rosloniec EF, Freed BM.

J Autoimmun. 2016 Aug;72:25-32. doi: 10.1016/j.jaut.2016.04.006. Epub 2016 Apr 30.

PMID:
27143337
6.

A Molecular Analysis of the Shared Epitope Hypothesis: Binding of Arthritogenic Peptides to DRB1*04 Alleles.

Anderson KM, Roark CL, Portas M, Aubrey MT, Rosloniec EF, Freed BM.

Arthritis Rheumatol. 2016 Jul;68(7):1627-36. doi: 10.1002/art.39636.

7.

The CII-specific autoimmune T-cell response develops in the presence of FTY720 but is regulated by enhanced Treg cells that inhibit the development of autoimmune arthritis.

Miller DC, Whittington KB, Brand DD, Hasty KA, Rosloniec EF.

Arthritis Res Ther. 2016 Jan 12;18:8. doi: 10.1186/s13075-015-0909-6.

8.

Peptide ligand structure and I-Aq binding avidity influence T cell signaling pathway utilization.

Myers LK, Cullins DL, Park JE, Yi AK, Brand DD, Rosloniec EF, Stuart JM, Kang AH.

Clin Immunol. 2015 Oct;160(2):188-97. doi: 10.1016/j.clim.2015.05.002. Epub 2015 May 14.

9.

Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis.

Tang B, Kim S, Hammond S, Cullins DL, Brand DD, Rosloniec EF, Stuart JM, Postlethwaite AE, Kang AH, Myers LK.

Arthritis Res Ther. 2014 Jan 10;16(1):R7. doi: 10.1186/ar4433.

10.

Engineered regulatory T cells coexpressing MHC class II:peptide complexes are efficient inhibitors of autoimmune T cell function and prevent the development of autoimmune arthritis.

Qian Z, Latham KA, Whittington KB, Miller DC, Brand DD, Rosloniec EF.

J Immunol. 2013 Jun 1;190(11):5382-91. doi: 10.4049/jimmunol.1300024. Epub 2013 Apr 29.

11.

Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis.

Kimata M, Cullins DL, Brown ML, Brand DD, Rosloniec EF, Myers LK, Stuart JM, Kang AH.

Arthritis Res Ther. 2012 May 8;14(3):R107. doi: 10.1186/ar3832.

12.

An autoantigen-specific, highly restricted T cell repertoire infiltrates the arthritic joints of mice in an HLA-DR1 humanized mouse model of autoimmune arthritis.

Qian Z, Latham KA, Whittington KB, Miller DC, Brand DD, Rosloniec EF.

J Immunol. 2010 Jul 1;185(1):110-8. doi: 10.4049/jimmunol.1000416. Epub 2010 May 28.

13.

Collagen-induced arthritis.

Rosloniec EF, Cremer M, Kang AH, Myers LK, Brand DD.

Curr Protoc Immunol. 2010 Apr;Chapter 15:Unit 15.5.1-25. doi: 10.1002/0471142735.im1505s89.

PMID:
20376842
14.

Collagen-induced arthritis.

Rosloniec EF, Cremer M, Kang A, Myers LK.

Curr Protoc Immunol. 2001 May;Chapter 15:Unit 15.5. doi: 10.1002/0471142735.im1505s20.

PMID:
18432737
15.

MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis.

Huan J, Kaler LJ, Mooney JL, Subramanian S, Hopke C, Vandenbark AA, Rosloniec EF, Burrows GG, Offner H.

J Immunol. 2008 Jan 15;180(2):1249-57.

16.

Collagen-induced arthritis.

Brand DD, Latham KA, Rosloniec EF.

Nat Protoc. 2007;2(5):1269-75.

PMID:
17546023
17.

Second-generation peptidomimetic inhibitors of antigen presentation effectively treat autoimmune diseases in HLA-DR-transgenic mouse models.

Rosloniec EF, Brandstetter T, Leyer S, Schwaiger FW, Nagy ZA.

J Autoimmun. 2006 Nov;27(3):182-95. Epub 2006 Nov 1.

18.

Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB1*0401) transgenic mice.

Sakurai Y, Brand DD, Tang B, Rosloniec EF, Stuart JM, Kang AH, Myers LK.

Arthritis Res Ther. 2006;8(5):R150.

19.
20.

Molecular characterization of an arthritogenic collagen peptide interacting with I-Ar.

Sakurai Y, Tang B, Rosloniec EF, Stuart JM, Kang AH, Myers LK.

Immunology. 2006 Jan;117(1):136-42.

21.
23.

Efficacy of modified recombinant type II collagen in modulating autoimmune arthritis.

Myers LK, Tang B, Brand DD, Rosloniec EF, Stuart JM, Kang AH.

Arthritis Rheum. 2004 Sep;50(9):3004-11.

24.

The mouse model of collagen-induced arthritis.

Brand DD, Kang AH, Rosloniec EF.

Methods Mol Med. 2004;102:295-312.

PMID:
15286392
25.
26.

T cell receptors recognizing type II collagen in HLA-DR-transgenic mice characterized by highly restricted V beta usage.

He X, Rosloniec EF, Myers LK, McColgan WL 3rd, Gumanovskaya M, Kang AH, Stuart JM.

Arthritis Rheum. 2004 Jun;50(6):1996-2004.

27.

An analog peptide that suppresses collagen-induced arthritis.

Myers LK, Sakurai Y, Rosloniec EF, Stuart JM, Kang AH.

Am J Med Sci. 2004 Apr;327(4):212-6.

PMID:
15084917
28.

Collagen-induced arthritis mediated by HLA-DR1 (*0101) and HLA-DR4 (*0401).

Rosloniec EF, Whittington KB, He X, Stuart JM, Kang AH.

Am J Med Sci. 2004 Apr;327(4):169-79.

PMID:
15084912
29.

Estradiol treatment redirects the isotype of the autoantibody response and prevents the development of autoimmune arthritis.

Latham KA, Zamora A, Drought H, Subramanian S, Matejuk A, Offner H, Rosloniec EF.

J Immunol. 2003 Dec 1;171(11):5820-7.

30.

Immunopathogenesis of collagen arthritis.

Brand DD, Kang AH, Rosloniec EF.

Springer Semin Immunopathol. 2003 Aug;25(1):3-18. Review.

PMID:
12904888
31.

Peptide-induced suppression of collagen-induced arthritis in HLA-DR1 transgenic mice.

Myers LK, Sakurai Y, Tang B, He X, Rosloniec EF, Stuart JM, Kang AH.

Arthritis Rheum. 2002 Dec;46(12):3369-77.

32.

Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity.

Rosloniec EF, Latham K, Guedez YB.

Arthritis Res. 2002;4(6):333-6. Epub 2002 Jul 17. Review.

33.
34.

A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness.

Zuo L, Cullen CM, DeLay ML, Thornton S, Myers LK, Rosloniec EF, Boivin GP, Hirsch R.

J Immunol. 2002 Mar 1;168(5):2554-9.

35.

Detection of early changes in autoimmune T cell phenotype and function following intravenous administration of type II collagen in a TCR-transgenic model.

Brand DD, Myers LK, Whittington KB, Latham KA, Stuart JM, Kang AH, Rosloniec EF.

J Immunol. 2002 Jan 1;168(1):490-8.

36.
37.

Genetic ablation of interferon-gamma up-regulates interleukin-1beta expression and enables the elicitation of collagen-induced arthritis in a nonsusceptible mouse strain.

Guedez YB, Whittington KB, Clayton JL, Joosten LA, van de Loo FA, van den Berg WB, Rosloniec EF.

Arthritis Rheum. 2001 Oct;44(10):2413-24.

38.

The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis.

Myers LK, Kang AH, Postlethwaite AE, Rosloniec EF, Morham SG, Shlopov BV, Goorha S, Ballou LR.

Arthritis Rheum. 2000 Dec;43(12):2687-93.

40.

Use of soluble peptide-DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis.

Kotzin BL, Falta MT, Crawford F, Rosloniec EF, Bill J, Marrack P, Kappler J.

Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):291-6.

41.

Intravenous tolerization with type II collagen induces interleukin-4-and interleukin-10-producing CD4+ T cells.

Gumanovskaya ML, Myers LK, Rosloniec EF, Stuart JM, Kang AH.

Immunology. 1999 Jul;97(3):466-73.

42.

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice.

Nakagawa TY, Brissette WH, Lira PD, Griffiths RJ, Petrushova N, Stock J, McNeish JD, Eastman SE, Howard ED, Clarke SR, Rosloniec EF, Elliott EA, Rudensky AY.

Immunity. 1999 Feb;10(2):207-17.

43.

Characterization of recombinant type II collagen: arthritogenicity and tolerogenicity in DBA/1 mice.

Myers LK, Brand DD, Ye XJ, Cremer MA, Rosloniec EF, Bodo M, Myllyharju J, Helaakoski T, Nokelainen M, Pihlajaniemi T, Kivirikko K, Yang CL, Ala-Kokko L, Prockop DJ, Notbohm H, Fietzek P, Stuart JM, Kang AH.

Immunology. 1998 Dec;95(4):631-9.

44.

Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones.

Fridkis-Hareli M, Rosloniec EF, Fugger L, Strominger JL.

Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12528-31.

45.

Characterization of a peptide analog of a determinant of type II collagen that suppresses collagen-induced arthritis.

Myers LK, Tang B, Rosloniec EF, Stuart JM, Chiang TM, Kang AH.

J Immunol. 1998 Oct 1;161(7):3589-95.

47.

Characterization of signal transduction through the TCR-zeta chain following T cell stimulation with analogue peptides of type II collagen 260-267.

Tang B, Myers LK, Rosloniec EF, Whittington KB, Stuart JM, Kang AH.

J Immunol. 1998 Apr 1;160(7):3135-42.

48.

Induction of autoimmune arthritis in HLA-DR4 (DRB1*0401) transgenic mice by immunization with human and bovine type II collagen.

Rosloniec EF, Brand DD, Myers LK, Esaki Y, Whittington KB, Zaller DM, Woods A, Stuart JM, Kang AH.

J Immunol. 1998 Mar 15;160(6):2573-8.

49.

Restricted TCR V alpha repertoire in the T cell response to a tolerogenic determinant of type II collagen.

Kawamura S, Miyahara H, Esaki Y, Myers LK, Rosloniec EF, Stuart JM, Kang AH.

J Immunol. 1997 Jun 15;158(12):6013-8.

PMID:
9190956
50.

An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen.

Rosloniec EF, Brand DD, Myers LK, Whittington KB, Gumanovskaya M, Zaller DM, Woods A, Altmann DM, Stuart JM, Kang AH.

J Exp Med. 1997 Mar 17;185(6):1113-22.

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