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Items: 15


TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence.

Bird TG, Müller M, Boulter L, Vincent DF, Ridgway RA, Lopez-Guadamillas E, Lu WY, Jamieson T, Govaere O, Campbell AD, Ferreira-Gonzalez S, Cole AM, Hay T, Simpson KJ, Clark W, Hedley A, Clarke M, Gentaz P, Nixon C, Bryce S, Kiourtis C, Sprangers J, Nibbs RJB, Van Rooijen N, Bartholin L, McGreal SR, Apte U, Barry ST, Iredale JP, Clarke AR, Serrano M, Roskams TA, Sansom OJ, Forbes SJ.

Sci Transl Med. 2018 Aug 15;10(454). pii: eaan1230. doi: 10.1126/scitranslmed.aan1230.


Cross-species immunohistochemical investigation of the activation of the liver progenitor cell niche in different types of liver disease.

Schotanus BA, van den Ingh TS, Penning LC, Rothuizen J, Roskams TA, Spee B.

Liver Int. 2009 Sep;29(8):1241-52. doi: 10.1111/j.1478-3231.2009.02024.x. Epub 2009 Apr 20.


Characterisation of the hepatic progenitor cell compartment in normal liver and in hepatitis: an immunohistochemical comparison between dog and man.

Ijzer J, Schotanus BA, Vander Borght S, Roskams TA, Kisjes R, Penning LC, Rothuizen J, van den Ingh TS.

Vet J. 2010 Jun;184(3):308-14. doi: 10.1016/j.tvjl.2009.02.016. Epub 2009 Apr 14.


Up-regulation and cytoprotective role of epithelial multidrug resistance-associated protein 1 in inflammatory bowel disease.

Blokzijl H, van Steenpaal A, Vander Borght S, Bok LI, Libbrecht L, Tamminga M, Geuken M, Roskams TA, Dijkstra G, Moshage H, Jansen PL, Faber KN.

J Biol Chem. 2008 Dec 19;283(51):35630-7. doi: 10.1074/jbc.M804374200. Epub 2008 Oct 6.


Up-regulation of breast cancer resistance protein expression in hepatoblastoma following chemotherapy: A study in patients and in vitro.

Vander Borght S, van Pelt J, van Malenstein H, Cassiman D, Renard M, Verslype C, Libbrecht L, Roskams TA.

Hepatol Res. 2008;38(11):1112-21. doi: 10.1111/j.1872-034X.2008.00381.x. Epub 2008 Jun 19.


Nuclear beta-catenin staining and absence of steatosis are indicators of hepatocellular adenomas with an increased risk of malignancy.

Van der Borght S, Libbrecht L, Katoonizadeh A, Aerts R, Nevens F, Verslype C, Roskams TA.

Histopathology. 2007 Dec;51(6):855-6. Epub 2007 Sep 28. No abstract available.


Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.

Blokzijl H, Vander Borght S, Bok LI, Libbrecht L, Geuken M, van den Heuvel FA, Dijkstra G, Roskams TA, Moshage H, Jansen PL, Faber KN.

Inflamm Bowel Dis. 2007 Jun;13(6):710-20.


Breast cancer resistance protein (BCRP/ABCG2) is expressed by progenitor cells/reactive ductules and hepatocytes and its expression pattern is influenced by disease etiology and species type: possible functional consequences.

Vander Borght S, Libbrecht L, Katoonizadeh A, van Pelt J, Cassiman D, Nevens F, Van Lommel A, Petersen BE, Fevery J, Jansen PL, Roskams TA.

J Histochem Cytochem. 2006 Sep;54(9):1051-9. Epub 2006 May 18.


Diagnostic and pathogenetic implications of the expression of hepatic transporters in focal lesions occurring in normal liver.

Vander Borght S, Libbrecht L, Blokzijl H, Faber KN, Moshage H, Aerts R, Van Steenbergen W, Jansen PL, Desmet VJ, Roskams TA.

J Pathol. 2005 Dec;207(4):471-82.


Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers.

Roskams TA, Theise ND, Balabaud C, Bhagat G, Bhathal PS, Bioulac-Sage P, Brunt EM, Crawford JM, Crosby HA, Desmet V, Finegold MJ, Geller SA, Gouw AS, Hytiroglou P, Knisely AS, Kojiro M, Lefkowitch JH, Nakanuma Y, Olynyk JK, Park YN, Portmann B, Saxena R, Scheuer PJ, Strain AJ, Thung SN, Wanless IR, West AB.

Hepatology. 2004 Jun;39(6):1739-45.


Progenitor cells in diseased human liver.

Roskams TA, Libbrecht L, Desmet VJ.

Semin Liver Dis. 2003 Nov;23(4):385-96. Review.


High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease.

Ros JE, Libbrecht L, Geuken M, Jansen PL, Roskams TA.

J Pathol. 2003 Aug;200(5):553-60.


ATP binding cassette transporter gene expression in rat liver progenitor cells.

Ros JE, Roskams TA, Geuken M, Havinga R, Splinter PL, Petersen BE, LaRusso NF, van der Kolk DM, Kuipers F, Faber KN, Müller M, Jansen PL.

Gut. 2003 Jul;52(7):1060-7.


NSP-encoded reticulons are neuroendocrine markers of a novel category in human lung cancer diagnosis.

van de Velde HJ, Senden NH, Roskams TA, Broers JL, Ramaekers FC, Roebroek AJ, Van de Ven WJ.

Cancer Res. 1994 Sep 1;54(17):4769-76.


Salivary gland involvement as initial presentation of Wegener's disease.

Vanhauwaert BG, Roskams TA, Vanneste SB, Knockaert DC.

Postgrad Med J. 1993 Aug;69(814):643-5.

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