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Items: 1 to 50 of 844

1.

Safety and Efficacy of Ledipasvir-Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6-11.

Murray KF, Balistreri WF, Bansal S, Whitworth S, Evans HM, Gonzalez-Peralta RP, Wen J, Massetto B, Kersey K, Shao J, Garrison KL, Parhy B, Brainard DM, Arnon R, Gillis LA, Jonas MM, Chuan-Hao L, Narkewicz MR, Schwarz K, Rosenthal P.

Hepatology. 2018 Aug 2. doi: 10.1002/hep.30123. [Epub ahead of print]

PMID:
30070726
2.

Bone Density in Children with Chronic Liver Disease Correlates with Growth and Cholestasis.

Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Rosenthal P, Hertel PM, Karpen SJ, Molleston JP, Murray KF, Schwarz KB, Squires RH, Teckman J, Turmelle YP, Alonso EM, Sherker AH, Magee JC, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN).

Hepatology. 2018 Jul 31. doi: 10.1002/hep.30196. [Epub ahead of print]

PMID:
30063078
3.

Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure.

Rodriguez-Barraquer I, Arinaitwe E, Jagannathan P, Kamya MR, Rosenthal PJ, Rek J, Dorsey G, Nankabirwa J, Staedke SG, Kilama M, Drakeley C, Ssewanyana I, Smith DL, Greenhouse B.

Elife. 2018 Jul 25;7. pii: e35832. doi: 10.7554/eLife.35832. [Epub ahead of print]

4.

Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance.

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2.

5.

Editorial: an expert consensus for the management of chronic hepatitis B in Asian Americans.

Ebel NH, Rosenthal P.

Aliment Pharmacol Ther. 2018 Jun;47(11):1541-1542. doi: 10.1111/apt.14620. No abstract available.

PMID:
29878412
6.

Association between Recent Overnight Travel and Risk of Malaria: A Prospective Cohort Study at Three Sites in Uganda.

Arinaitwe E, Dorsey G, Nankabirwa JI, Kigozi SP, Katureebe A, Kakande E, Rek J, Rosenthal PJ, Drakeley C, Kamya MR, Staedke SG.

Clin Infect Dis. 2018 Jun 4. doi: 10.1093/cid/ciy478. [Epub ahead of print]

PMID:
29868722
7.

Reconciling Conflicting Results From Pediatric Sepsis Studies: The Need for Context-Specific Sepsis Bundles.

Kortz T, Rosenthal PJ.

Pediatr Crit Care Med. 2018 Jun;19(6):594-595. doi: 10.1097/PCC.0000000000001568. No abstract available.

PMID:
29863649
8.

Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies.

Bull LN, Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Dodge JL, Emerick K, Wanty C, Wali S, Blanchard S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Houwen R, Lobritto S, Hupertz V, McClean P, Mieli-Vergani G, Sokal E, Rosenthal P, Whitington PF, Pawlowska J, Thompson RJ.

Hepatol Commun. 2018 Mar 30;2(5):515-528. doi: 10.1002/hep4.1168. eCollection 2018 May.

9.

A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.

Narkewicz MR, Horslen S, Hardison RM, Shneider BL, Rodriguez-Baez N, Alonso EM, Ng VL, Leonis MA, Loomes KM, Rudnick DA, Rosenthal P, Romero R, Subbarao GC, Li R, Belle SH, Squires RH; Pediatric Acute Liver Failure Study Group.

Clin Gastroenterol Hepatol. 2018 Apr 30. pii: S1542-3565(18)30455-5. doi: 10.1016/j.cgh.2018.04.050. [Epub ahead of print]

PMID:
29723692
10.

De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation.

Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H.

Nature. 2018 May;557(7704):247-251. doi: 10.1038/s41586-018-0075-5. Epub 2018 May 2.

PMID:
29720662
11.

Does reduced zona pellucida binding protein 2 (ZPBP2) expression on chromosome 17q21 protect against asthma?

Miller M, Vuong C, Garcia MF, Rosenthal P, Das S, Weng N, Pham A, Kim YJ, Broide DH.

J Allergy Clin Immunol. 2018 Aug;142(2):706-709.e4. doi: 10.1016/j.jaci.2018.04.011. Epub 2018 Apr 28. No abstract available.

PMID:
29709669
12.

Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease.

Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).

J Pediatr. 2018 Jul;198:76-83.e2. doi: 10.1016/j.jpeds.2018.02.038. Epub 2018 Apr 13.

PMID:
29661561
13.

Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance.

Siddiqui FA, Cabrera M, Wang M, Brashear A, Kemirembe K, Wang Z, Miao J, Chookajorn T, Yang Z, Cao Y, Dong G, Rosenthal PJ, Cui L.

J Infect Dis. 2018 Jul 2;218(3):434-442. doi: 10.1093/infdis/jiy188.

PMID:
29659945
14.

An OX40/OX40L interaction directs successful immunity to hepatitis B virus.

Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL.

Sci Transl Med. 2018 Mar 21;10(433). pii: eaah5766. doi: 10.1126/scitranslmed.aah5766.

15.

Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine.

Savic RM, Jagannathan P, Kajubi R, Huang L, Zhang N, Were M, Kakuru A, Muhindo MK, Mwebaza N, Wallender E, Clark TD, Opira B, Kamya M, Havlir DV, Rosenthal PJ, Dorsey G, Aweeka FT.

Clin Infect Dis. 2018 Mar 14. doi: 10.1093/cid/ciy218. [Epub ahead of print]

PMID:
29547881
16.

Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study.

Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, Haber BH, Sherker AH, Magee JC, Sokol RJ; Childhood Liver Disease Research Network (ChiLDReN).

J Pediatr. 2018 May;196:139-147.e3. doi: 10.1016/j.jpeds.2017.12.048. Epub 2018 Mar 5.

PMID:
29519540
17.

Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability.

Capela R, Magalhães J, Miranda D, Machado M, Sanches-Vaz M, Albuquerque IS, Sharma M, Gut J, Rosenthal PJ, Frade R, Perry MJ, Moreira R, Prudêncio M, Lopes F.

Eur J Med Chem. 2018 Apr 10;149:69-78. doi: 10.1016/j.ejmech.2018.02.048. Epub 2018 Feb 19.

PMID:
29499488
18.

Clinical consequences of submicroscopic malaria parasitaemia in Uganda.

Katrak S, Nayebare P, Rek J, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B.

Malar J. 2018 Feb 5;17(1):67. doi: 10.1186/s12936-018-2221-9.

19.

Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010.

Verstraete SG, Wojcicki JM, Perito ER, Rosenthal P.

Environ Health. 2018 Feb 1;17(1):12. doi: 10.1186/s12940-018-0356-3.

20.

Predicting Optimal Dihydroartemisinin-Piperaquine Regimens to Prevent Malaria During Pregnancy for Human Immunodeficiency Virus-Infected Women Receiving Efavirenz.

Wallender E, Vucicevic K, Jagannathan P, Huang L, Natureeba P, Kakuru A, Muhindo M, Nakalembe M, Havlir D, Kamya M, Aweeka F, Dorsey G, Rosenthal PJ, Savic RM.

J Infect Dis. 2018 Mar 5;217(6):964-972. doi: 10.1093/infdis/jix660.

PMID:
29272443
21.

Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors.

Perito ER, Phelps A, Vase T, Feldstein VA, Lustig RH, Rosenthal P.

J Pediatr. 2018 Feb;193:119-127.e1. doi: 10.1016/j.jpeds.2017.10.006. Epub 2017 Dec 7.

PMID:
29224938
22.

Quality of life in adolescents with hepatitis C treated with sofosbuvir and ribavirin.

Younossi ZM, Stepanova M, Schwarz KB, Wirth S, Rosenthal P, Gonzalez-Peralta R, Murray K, Henry L, Hunt S.

J Viral Hepat. 2018 Apr;25(4):354-362. doi: 10.1111/jvh.12830. Epub 2017 Dec 26.

PMID:
29193603
23.

"The Way We Were" Ken Warren's Legacy and Modern Investments in Global Health.

Panosian C, Rosenthal PJ.

Am J Trop Med Hyg. 2017 Dec;97(6):1955-1957. doi: 10.4269/ajtmh.17-0829. No abstract available.

24.

Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation.

Rani A, Singh A, Gut J, Rosenthal PJ, Kumar V.

Eur J Med Chem. 2018 Jan 1;143:150-156. doi: 10.1016/j.ejmech.2017.11.033. Epub 2017 Nov 16.

PMID:
29174811
25.

Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease.

Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B.

Hepatol Commun. 2017 Sep;1(7):609-622. doi: 10.1002/hep4.1068. Epub 2017 Jul 17.

26.

Performance of Loop-Mediated Isothermal Amplification for the Identification of Submicroscopic Plasmodium falciparum Infection in Uganda.

Katrak S, Murphy M, Nayebare P, Rek J, Smith M, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B.

Am J Trop Med Hyg. 2017 Dec;97(6):1777-1781. doi: 10.4269/ajtmh.17-0225. Epub 2017 Oct 5.

PMID:
29016335
27.

Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study.

Mpimbaza A, Ndeezi G, Katahoire A, Rosenthal PJ, Karamagi C.

Am J Trop Med Hyg. 2017 Nov;97(5):1513-1523. doi: 10.4269/ajtmh.17-0056. Epub 2017 Oct 10.

PMID:
29016322
28.

Comparative Prevalence of Plasmodium falciparum Resistance-Associated Genetic Polymorphisms in Parasites Infecting Humans and Mosquitoes in Uganda.

Conrad MD, Mota D, Musiime A, Kilama M, Rek J, Kamya M, Dorsey G, Rosenthal PJ.

Am J Trop Med Hyg. 2017 Nov;97(5):1576-1580. doi: 10.4269/ajtmh.17-0351. Epub 2017 Oct 10.

PMID:
29016309
29.

Plasmodium Species Infecting Children Presenting with Malaria in Uganda.

Asua V, Tukwasibwe S, Conrad M, Walakira A, Nankabirwa JI, Mugenyi L, Kamya MR, Nsobya SL, Rosenthal PJ.

Am J Trop Med Hyg. 2017 Sep;97(3):753-757. doi: 10.4269/ajtmh.17-0345.

PMID:
28990911
30.

Let's Eliminate Diseases, Not Institutes: The Case for the Fogarty International Center.

Rosenthal PJ, Goraleski KA, Rabinovich NR, Walker PF.

Am J Trop Med Hyg. 2017 Sep;97(3):629-630. doi: 10.4269/ajtmh.17-0601. No abstract available.

31.

Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda.

Conrad MD, Mota D, Foster M, Tukwasibwe S, Legac J, Tumwebaze P, Whalen M, Kakuru A, Nayebare P, Wallender E, Havlir DV, Jagannathan P, Huang L, Aweeka F, Kamya MR, Dorsey G, Rosenthal PJ.

J Infect Dis. 2017 Nov 15;216(8):1008-1017. doi: 10.1093/infdis/jix421.

PMID:
28968782
32.

Activating transcription factor 6α (ATF6α) regulates airway hyperreactivity, smooth muscle proliferation, and contractility.

Unno H, Miller M, Rosenthal P, Beppu A, Das S, Broide DH.

J Allergy Clin Immunol. 2018 Jan;141(1):439-442.e4. doi: 10.1016/j.jaci.2017.07.053. Epub 2017 Sep 27. No abstract available.

PMID:
28958904
33.

Health-related Quality of Life in Adolescent Patients With Hepatitis C Genotype 1 Treated With Sofosbuvir and Ledipasvir.

Younossi ZM, Stepanova M, Balistreri W, Schwarz K, Murray KF, Rosenthal P, Bansal S, Hunt S.

J Pediatr Gastroenterol Nutr. 2018 Jan;66(1):112-116. doi: 10.1097/MPG.0000000000001754.

PMID:
28957984
34.

Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda.

Walakira A, Tukwasibwe S, Kiggundu M, Verra F, Kakeeto P, Ruhamyankaka E, Drakeley C, Dorsey G, Kamya MR, Nsobya SL, Rosenthal PJ.

Infect Genet Evol. 2017 Nov;55:281-287. doi: 10.1016/j.meegid.2017.09.021. Epub 2017 Sep 19.

PMID:
28939159
35.

Pediatric liver failure: we came, we saw, but have we conquered?

Smith SK, Rosenthal P.

F1000Res. 2017 Aug 22;6:1540. doi: 10.12688/f1000research.9623.1. eCollection 2017. Review.

36.

Changing Antimalarial Drug Sensitivities in Uganda.

Rasmussen SA, Ceja FG, Conrad MD, Tumwebaze PK, Byaruhanga O, Katairo T, Nsobya SL, Rosenthal PJ, Cooper RA.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01516-17. doi: 10.1128/AAC.01516-17. Print 2017 Dec.

37.

Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma.

Chen J, Miller M, Unno H, Rosenthal P, Sanderson MJ, Broide DH.

J Allergy Clin Immunol. 2018 Jul;142(1):207-218.e6. doi: 10.1016/j.jaci.2017.08.015. Epub 2017 Sep 7.

PMID:
28889952
38.

Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation.

Song DJ, Miller M, Beppu A, Rosenthal P, Das S, Karta M, Vuong C, Mehta AK, Croft M, Broide DH.

J Immunol. 2017 Oct 1;199(7):2215-2224. doi: 10.4049/jimmunol.1601412. Epub 2017 Aug 21.

PMID:
28827284
39.

Development of Novel Peptide-Based Michael Acceptors Targeting Rhodesain and Falcipain-2 for the Treatment of Neglected Tropical Diseases (NTDs).

Previti S, Ettari R, Cosconati S, Amendola G, Chouchene K, Wagner A, Hellmich UA, Ulrich K, Krauth-Siegel RL, Wich PR, Schmid I, Schirmeister T, Gut J, Rosenthal PJ, Grasso S, Zappalà M.

J Med Chem. 2017 Aug 24;60(16):6911-6923. doi: 10.1021/acs.jmedchem.7b00405. Epub 2017 Aug 11.

PMID:
28763614
40.

4-Aminoquinoline-chalcone/-N-acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation.

Kumar S, Saini A, Gut J, Rosenthal PJ, Raj R, Kumar V.

Eur J Med Chem. 2017 Sep 29;138:993-1001. doi: 10.1016/j.ejmech.2017.07.041. Epub 2017 Jul 22.

PMID:
28756265
41.

Shorter Leukocyte Telomere Length in Relation to Presumed Nonalcoholic Fatty Liver Disease in Mexican-American Men in NHANES 1999-2002.

Wojcicki JM, Rehkopf D, Epel E, Rosenthal P.

Int J Hepatol. 2017;2017:8435178. doi: 10.1155/2017/8435178. Epub 2017 Jun 27.

42.

Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial.

O'Brien KS, Cotter SY, Amza A, Kadri B, Nassirou B, Stoller NE, Zhou Z, Cotter C, West SK, Bailey RL, Rosenthal PJ, Gaynor BD, Porco TC, Lietman TM.

Am J Trop Med Hyg. 2017 Sep;97(3):696-701. doi: 10.4269/ajtmh.16-0487. Epub 2017 Jul 19.

43.

Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.

Blank BR, Gut J, Rosenthal PJ, Renslo AR.

J Med Chem. 2017 Jul 27;60(14):6400-6407. doi: 10.1021/acs.jmedchem.7b00699. Epub 2017 Jul 10.

44.

Building bridges between cellular and molecular structural biology.

Patwardhan A, Brandt R, Butcher SJ, Collinson L, Gault D, Grünewald K, Hecksel C, Huiskonen JT, Iudin A, Jones ML, Korir PK, Koster AJ, Lagerstedt I, Lawson CL, Mastronarde D, McCormick M, Parkinson H, Rosenthal PB, Saalfeld S, Saibil HR, Sarntivijai S, Solanes Valero I, Subramaniam S, Swedlow JR, Tudose I, Winn M, Kleywegt GJ.

Elife. 2017 Jul 6;6. pii: e25835. doi: 10.7554/eLife.25835.

45.

Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.

Zhang YK, Plattner JJ, Easom EE, Jacobs RT, Guo D, Freund YR, Berry P, Ciaravino V, Erve JCL, Rosenthal PJ, Campo B, Gamo FJ, Sanz LM, Cao J.

J Med Chem. 2017 Jul 13;60(13):5889-5908. doi: 10.1021/acs.jmedchem.7b00621. Epub 2017 Jun 29.

PMID:
28635296
46.

Sofosbuvir and ribavirin in adolescents 12-17 years old with hepatitis C virus genotype 2 or 3 infection.

Wirth S, Rosenthal P, Gonzalez-Peralta RP, Jonas MM, Balistreri WF, Lin CH, Hardikar W, Kersey K, Massetto B, Kanwar B, Brainard DM, Shao J, Svarovskaia E, Kirby B, Arnon R, Murray KF, Schwarz KB.

Hepatology. 2017 Oct;66(4):1102-1110. doi: 10.1002/hep.29278. Epub 2017 Aug 26.

PMID:
28543053
47.

Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia?

Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Whitington PF, Rosenthal P, Squires RH, Guthery SL, Arnon R, Schwarz KB, Turmelle YP, Sherker AH, Sokol RJ; Childhood Liver Disease Research Network.

PLoS One. 2017 May 11;12(5):e0176275. doi: 10.1371/journal.pone.0176275. eCollection 2017.

48.

Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Exert Inverse Selective Pressure on Plasmodium Falciparum Drug Sensitivity-Associated Haplotypes in Uganda.

Taylor AR, Flegg JA, Holmes CC, Guérin PJ, Sibley CH, Conrad MD, Dorsey G, Rosenthal PJ.

Open Forum Infect Dis. 2016 Oct 25;4(1):ofw229. doi: 10.1093/ofid/ofw229. eCollection 2017 Winter.

49.

Hepatic steatosis after pediatric liver transplant.

Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA, Rosenthal P.

Liver Transpl. 2017 Jul;23(7):957-967. doi: 10.1002/lt.24773.

50.

The Relative Effects of Artemether-lumefantrine and Non-artemisinin Antimalarials on Gametocyte Carriage and Transmission of Plasmodium falciparum: A Systematic Review and Meta-analysis.

Ippolito MM, Johnson J, Mullin C, Mallow C, Morgan N, Wallender E, Li T, Rosenthal PJ.

Clin Infect Dis. 2017 Aug 1;65(3):486-494. doi: 10.1093/cid/cix336. Review.

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