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Items: 1 to 50 of 142

1.

Experimentally guided computational antibody affinity maturation with de novo docking, modelling and rational design.

Cannon DA, Shan L, Du Q, Shirinian L, Rickert KW, Rosenthal KL, Korade M 3rd, van Vlerken-Ysla LE, Buchanan A, Vaughan TJ, Damschroder MM, Popovic B.

PLoS Comput Biol. 2019 May 1;15(5):e1006980. doi: 10.1371/journal.pcbi.1006980. eCollection 2019 May.

2.

TLR10 Senses HIV-1 Proteins and Significantly Enhances HIV-1 Infection.

Henrick BM, Yao XD, Zahoor MA, Abimiku A, Osawe S, Rosenthal KL.

Front Immunol. 2019 Mar 15;10:482. doi: 10.3389/fimmu.2019.00482. eCollection 2019.

3.

Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.

Shan L, Mody N, Sormani P, Rosenthal KL, Damschroder MM, Esfandiary R.

Mol Pharm. 2018 Dec 3;15(12):5697-5710. doi: 10.1021/acs.molpharmaceut.8b00867. Epub 2018 Nov 15.

PMID:
30395473
4.

Breastfeeding mitigates the effects of maternal HIV on infant infectious morbidity in the Option B+ era.

Tchakoute CT, Sainani KL, Osawe S, Datong P, Kiravu A, Rosenthal KL, Gray CM, Cameron DW, Abimiku A, Jaspan HB; INFANT study team.

AIDS. 2018 Oct 23;32(16):2383-2391. doi: 10.1097/QAD.0000000000001974.

PMID:
30134300
5.

Breastfeeding Behaviors and the Innate Immune System of Human Milk: Working Together to Protect Infants against Inflammation, HIV-1, and Other Infections.

Henrick BM, Yao XD, Nasser L, Roozrogousheh A, Rosenthal KL.

Front Immunol. 2017 Nov 29;8:1631. doi: 10.3389/fimmu.2017.01631. eCollection 2017. Review.

6.

Insights into Soluble Toll-Like Receptor 2 as a Downregulator of Virally Induced Inflammation.

Henrick BM, Yao XD, Taha AY, German JB, Rosenthal KL.

Front Immunol. 2016 Aug 2;7:291. doi: 10.3389/fimmu.2016.00291. eCollection 2016. Review.

7.

Generation and Characterization of an IgG4 Monomeric Fc Platform.

Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V.

PLoS One. 2016 Aug 1;11(8):e0160345. doi: 10.1371/journal.pone.0160345. eCollection 2016.

8.

Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava.

Calicchio KW, Bennett RA, Laraio LC, Weisse C, Zwingenberger AL, Rosenthal KL, Johnston MS, Campbell VL, Solomon JA.

Am J Vet Res. 2016 May;77(5):540-7. doi: 10.2460/ajvr.77.5.540.

PMID:
27111022
9.

HIV-1 Structural Proteins Serve as PAMPs for TLR2 Heterodimers Significantly Increasing Infection and Innate Immune Activation.

Henrick BM, Yao XD, Rosenthal KL; INFANT study team.

Front Immunol. 2015 Aug 19;6:426. doi: 10.3389/fimmu.2015.00426. eCollection 2015.

10.

Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection.

Jeyanathan M, Thanthrige-Don N, Afkhami S, Lai R, Damjanovic D, Zganiacz A, Feng X, Yao XD, Rosenthal KL, Medina MF, Gauldie J, Ertl HC, Xing Z.

Mucosal Immunol. 2015 Nov;8(6):1373-87. doi: 10.1038/mi.2015.29. Epub 2015 Apr 15.

PMID:
25872483
11.

Soluble toll-like receptor 2 is significantly elevated in HIV-1 infected breast milk and inhibits HIV-1 induced cellular activation, inflammation and infection.

Henrick BM, Yao XD, Drannik AG, Abimiku A, Rosenthal KL; INFANT Study Team.

AIDS. 2014 Sep 10;28(14):2023-32. doi: 10.1097/QAD.0000000000000381.

PMID:
25265071
12.

Acting locally: innate mucosal immunity in resistance to HIV-1 infection in Kenyan commercial sex workers.

Yao XD, Omange RW, Henrick BM, Lester RT, Kimani J, Ball TB, Plummer FA, Rosenthal KL.

Mucosal Immunol. 2014 Mar;7(2):268-79. doi: 10.1038/mi.2013.44. Epub 2013 Jun 26.

PMID:
23801306
13.

Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.

Drannik AG, Nag K, Sallenave JM, Rosenthal KL.

J Virol. 2013 Jul;87(13):7526-38. doi: 10.1128/JVI.02243-12. Epub 2013 May 1.

14.

Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells.

Drannik AG, Nag K, Yao XD, Henrick BM, Ball TB, Plummer FA, Wachihi C, Kimani J, Rosenthal KL.

PLoS One. 2012;7(12):e52738. doi: 10.1371/journal.pone.0052738. Epub 2012 Dec 27.

15.

Milk matters: soluble Toll-like receptor 2 (sTLR2) in breast milk significantly inhibits HIV-1 infection and inflammation.

Henrick BM, Nag K, Yao XD, Drannik AG, Aldrovandi GM, Rosenthal KL.

PLoS One. 2012;7(7):e40138. doi: 10.1371/journal.pone.0040138. Epub 2012 Jul 6.

16.

Trappin-2/elafin modulate innate immune responses of human endometrial epithelial cells to PolyI:C.

Drannik AG, Nag K, Yao XD, Henrick BM, Sallenave JM, Rosenthal KL.

PLoS One. 2012;7(4):e35866. doi: 10.1371/journal.pone.0035866. Epub 2012 Apr 24.

17.

Anti-HIV-1 activity of elafin is more potent than its precursor's, trappin-2, in genital epithelial cells.

Drannik AG, Nag K, Yao XD, Henrick BM, Jain S, Ball TB, Plummer FA, Wachihi C, Kimani J, Rosenthal KL.

J Virol. 2012 Apr;86(8):4599-610. doi: 10.1128/JVI.06561-11. Epub 2012 Feb 15.

18.

Bilateral traumatic temporomandibular joint luxation in a rat.

Shientag LJ, Rosenthal KL, Chandler HK, Wheeler SM.

Comp Med. 2011 Dec;61(6):510-3.

19.

War and peace between WAP and HIV: role of SLPI, trappin-2, elafin and ps20 in susceptibility to HIV infection.

Drannik AG, Henrick BM, Rosenthal KL.

Biochem Soc Trans. 2011 Oct;39(5):1427-32. doi: 10.1042/BST0391427. Review.

PMID:
21936827
20.

Herpes simplex virus type 2 virion host shutoff protein suppresses innate dsRNA antiviral pathways in human vaginal epithelial cells.

Yao XD, Rosenthal KL.

J Gen Virol. 2011 Sep;92(Pt 9):1981-93. doi: 10.1099/vir.0.030296-0. Epub 2011 Jun 1.

PMID:
21632561
21.

The gp41 epitope, QARVLAVERY, is highly conserved and a potent inducer of IgA that neutralizes HIV-1 and inhibits viral transcytosis.

Jain S, Rosenthal KL.

Mucosal Immunol. 2011 Sep;4(5):539-53. doi: 10.1038/mi.2011.21. Epub 2011 Apr 27. Erratum in: Mucosal Immunol. 2011 Nov;4(6):695.

PMID:
21525865
22.

IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells.

Boudreau JE, Stephenson KB, Wang F, Ashkar AA, Mossman KL, Lenz LL, Rosenthal KL, Bramson JL, Lichty BD, Wan Y.

Cancer Res. 2011 Apr 1;71(7):2497-506. doi: 10.1158/0008-5472.CAN-10-3025. Epub 2011 Feb 9.

23.
24.

Multiple tandem copies of conserved gp41 epitopes incorporated in gag virus-like particles elicit systemic and mucosal antibodies in an optimized heterologous vector delivery regimen.

Jain S, Patrick AJ, Rosenthal KL.

Vaccine. 2010 Oct 8;28(43):7070-80. doi: 10.1016/j.vaccine.2010.08.009. Epub 2010 Aug 17.

PMID:
20723627
25.

Intravaginal infection with herpes simplex virus type-2 (HSV-2) generates a functional effector memory T cell population that persists in the murine genital tract.

Tang VA, Rosenthal KL.

J Reprod Immunol. 2010 Dec;87(1-2):39-44. doi: 10.1016/j.jri.2010.06.155. Epub 2010 Aug 4.

PMID:
20688399
26.

Development of functional human NK cells in an immunodeficient mouse model with the ability to provide protection against tumor challenge.

Kwant-Mitchell A, Pek EA, Rosenthal KL, Ashkar AA.

PLoS One. 2009 Dec 21;4(12):e8379. doi: 10.1371/journal.pone.0008379.

27.

Mucosal innate and adaptive immune responses against herpes simplex virus type 2 in a humanized mouse model.

Kwant-Mitchell A, Ashkar AA, Rosenthal KL.

J Virol. 2009 Oct;83(20):10664-76. doi: 10.1128/JVI.02584-08. Epub 2009 Aug 5.

28.

HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers.

Lester RT, Yao XD, Ball TB, McKinnon LR, Omange WR, Kaul R, Wachihi C, Jaoko W, Rosenthal KL, Plummer FA.

PLoS One. 2009 May 21;4(5):e5644. doi: 10.1371/journal.pone.0005644.

29.

Evaluation of mucosal and seborrheic sites for staphylococci in two populations of captive psittacines.

Briscoe JA, Morris DO, Rosenthal KL, Shofer FS, Rankin SC.

J Am Vet Med Assoc. 2009 Apr 1;234(7):901-5. doi: 10.2460/javma.234.7.901.

PMID:
19335240
30.

Methicillin-resistant Staphylococcus aureus-associated dermatitis in a Congo African grey parrot (Psittacus erithacus erithacus).

Briscoe JA, Morris DO, Rankin SC, Hendrick MJ, Rosenthal KL.

J Avian Med Surg. 2008 Dec;22(4):336-43.

PMID:
19216263
31.

Immunization with adenovirus at the large intestinal mucosa as an effective vaccination strategy against sexually transmitted viral infection.

Zhu Q, Thomson CW, Rosenthal KL, McDermott MR, Collins SM, Gauldie J.

Mucosal Immunol. 2008 Jan;1(1):78-88. doi: 10.1038/mi.2007.3.

PMID:
19079163
32.

Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women.

Nazli A, Yao XD, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C.

Antiviral Res. 2009 Feb;81(2):103-12. doi: 10.1016/j.antiviral.2008.10.005. Epub 2008 Nov 12.

PMID:
19013198
33.

Tweaking Innate Immunity: the Promise of Innate Immunologicals As Anti-infectives.

Rosenthal KL.

Can J Infect Dis Med Microbiol. 2006 Sep;17(5):307-14.

34.

Toll-like receptor expression and responsiveness are increased in viraemic HIV-1 infection.

Lester RT, Yao XD, Ball TB, McKinnon LR, Kaul R, Wachihi C, Jaoko W, Plummer FA, Rosenthal KL.

AIDS. 2008 Mar 30;22(6):685-94. doi: 10.1097/QAD.0b013e3282f4de35.

PMID:
18356597
35.

Persistently HIV-1 seronegative Nairobi sex workers are susceptible to in vitro infection.

Bienzle D, Macdonald KS, Copeland KF, Bwayo JJ, Plummer FA, Rosenthal KL.

Can J Infect Dis. 2000 Sep;11(5):259-63.

36.

Infiltrative lipoma in a blue-crowned conure (Aratinga acuticaudata).

Mehler SJ, Briscoe JA, Hendrick MJ, Rosenthal KL.

J Avian Med Surg. 2007 Jun;21(2):146-9.

PMID:
18065137
38.

Susceptibility of human female primary genital epithelial cells to herpes simplex virus, type-2 and the effect of TLR3 ligand and sex hormones on infection.

MacDonald EM, Savoy A, Gillgrass A, Fernandez S, Smieja M, Rosenthal KL, Ashkar AA, Kaushic C.

Biol Reprod. 2007 Dec;77(6):1049-59. Epub 2007 Sep 19.

PMID:
17881767
39.

Cutaneous neoplasms in pet rabbits: a retrospective study.

von Bomhard W, Goldschmidt MH, Shofer FS, Perl L, Rosenthal KL, Mauldin EA.

Vet Pathol. 2007 Sep;44(5):579-88.

PMID:
17846230
40.

Expression of Toll-like receptors in murine vaginal epithelium is affected by the estrous cycle and stromal cells.

Yao XD, Fernandez S, Kelly MM, Kaushic C, Rosenthal KL.

J Reprod Immunol. 2007 Oct;75(2):106-19. Epub 2007 Jun 18.

PMID:
17572507
41.

Immune-mediated hemolytic anemia in an eclectus parrot.

Johnston MS, Son TT, Rosenthal KL.

J Am Vet Med Assoc. 2007 Apr 1;230(7):1028-31.

PMID:
17397343
42.

Plasma biochemical reference intervals for koi.

Palmeiro BS, Rosenthal KL, Lewbart GA, Shofer FS.

J Am Vet Med Assoc. 2007 Mar 1;230(5):708-12.

PMID:
17331056
43.

Distribution of Malassezia organisms on the skin of unaffected psittacine birds and psittacine birds with feather-destructive behavior.

Preziosi DE, Morris DO, Johnston MS, Rosenthal KL, O'Shea K, Rankin SC.

J Am Vet Med Assoc. 2006 Jan 15;228(2):216-21.

PMID:
16426189
44.

Treatment of intravaginal HSV-2 infection in mice: a comparison of CpG oligodeoxynucleotides and resiquimod (R-848).

McCluskie MJ, Cartier JL, Patrick AJ, Sajic D, Weeratna RD, Rosenthal KL, Davis HL.

Antiviral Res. 2006 Feb;69(2):77-85. Epub 2005 Dec 5.

PMID:
16377001
45.

Psittacine plasma concentrations of elements: daily fluctuations and clinical implications.

Rosenthal KL, Johnston MS, Shofer FS, Poppenga RH.

J Vet Diagn Invest. 2005 May;17(3):239-44.

PMID:
15945379
46.

Assessment of the reliability of plasma electrophoresis in birds.

Rosenthal KL, Johnston MS, Shofer FS.

Am J Vet Res. 2005 Mar;66(3):375-8.

PMID:
15822578
47.

Vaccines in the public eye.

Ritvo P, Wilson K, Willms D, Upshur R, Goldman A, Kelvin D, Rosenthal KL, Rinfret A, Kaul R, Krahn M; CANVAC Sociobehavioural Study Group.

Nat Med. 2005 Apr;11(4 Suppl):S20-4.

PMID:
15812485
48.
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