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Items: 1 to 50 of 331

1.

Discovery and characterization of potent IL-21 neutralizing antibodies via a novel alternating antigen immunization and humanization strategy.

Varkey R, Du Q, Karnell JL, Xiao X, Casey KA, Woods R, Rosenthal K, Wilson S, Dall'Acqua WF, Wu H, Herbst R, Ettinger R, Damschroder M.

PLoS One. 2019 Jan 25;14(1):e0211236. doi: 10.1371/journal.pone.0211236. eCollection 2019.

2.

Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.

Shan L, Mody N, Sormani P, Rosenthal KL, Damschroder MM, Esfandiary R.

Mol Pharm. 2018 Nov 15. doi: 10.1021/acs.molpharmaceut.8b00867. [Epub ahead of print]

PMID:
30395473
3.

Adaptation of the Roseman 6-Point Mastery Learning Model to the College of Medicine Program.

Lazerson J, Rosenthal J, Glaubensklee C, Hunt T, Morgenstern B, Pamidimukkala J, Penn DM, Rosenthal K, Sarsekeyeva M, Wragg S.

J Med Educ Curric Dev. 2018 Oct 4;5:2382120518803111. doi: 10.1177/2382120518803111. eCollection 2018 Jan-Dec.

4.

Evaluation of alpha-II-spectrin breakdown products as potential biomarkers for early recognition and severity of aneurysmal subarachnoid hemorrhage.

Papa L, Rosenthal K, Silvestri F, Axley JC, Kelly JM, Lewis SB.

Sci Rep. 2018 Sep 6;8(1):13308. doi: 10.1038/s41598-018-31631-y.

5.

Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models.

Tkaczyk C, Semenova E, Shi YY, Rosenthal K, Oganesyan V, Warrener P, Stover CK, Sellman BR.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01033-18. doi: 10.1128/AAC.01033-18. Print 2018 Nov.

6.

Breastfeeding mitigates the effects of maternal HIV on infant infectious morbidity in the Option B+ era.

Tchakoute CT, Sainani KL, Osawe S, Datong P, Kiravu A, Rosenthal KL, Gray CM, Cameron DW, Abimiku A, Jaspan HB; INFANT study team.

AIDS. 2018 Oct 23;32(16):2383-2391. doi: 10.1097/QAD.0000000000001974.

PMID:
30134300
7.

Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates.

Tabor DE, Oganesyan V, Keller AE, Yu L, McLaughlin RE, Song E, Warrener P, Rosenthal K, Esser M, Qi Y, Ruzin A, Stover CK, DiGiandomenico A.

J Infect Dis. 2018 Nov 5;218(12):1983-1994. doi: 10.1093/infdis/jiy438.

PMID:
30016475
8.

Structural insights into the mechanism of action of a biparatopic anti-HER2 antibody.

Oganesyan V, Peng L, Bee JS, Li J, Perry SR, Comer F, Xu L, Cook K, Senthil K, Clarke L, Rosenthal K, Gao C, Damschroder M, Wu H, Dall'Acqua W.

J Biol Chem. 2018 Jun 1;293(22):8439-8448. doi: 10.1074/jbc.M117.818013. Epub 2018 Apr 18.

9.

Tumor uptake of pegylated diabodies: Balancing systemic clearance and vascular transport.

Li Q, White JB, Peterson NC, Rickert KW, Lloyd CO, Allen KL, Rosenthal K, Gao X, Wu H, Dall'Acqua WF, Borrok MJ, Tsui P.

J Control Release. 2018 Jun 10;279:126-135. doi: 10.1016/j.jconrel.2018.04.013. Epub 2018 Apr 11.

PMID:
29653224
10.

Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus.

Riggs JM, Hanna RN, Rajan B, Zerrouki K, Karnell JL, Sagar D, Vainshtein I, Farmer E, Rosenthal K, Morehouse C, de Los Reyes M, Schifferli K, Liang M, Sanjuan MA, Sims GP, Kolbeck R.

Lupus Sci Med. 2018 Apr 5;5(1):e000261. doi: 10.1136/lupus-2018-000261. eCollection 2018.

11.

Evaluation of SNAP cPL, Spec cPL, VetScan cPL Rapid Test, and Precision PSL Assays for the Diagnosis of Clinical Pancreatitis in Dogs.

Cridge H, MacLeod AG, Pachtinger GE, Mackin AJ, Sullivant AM, Thomason JM, Archer TM, Lunsford KV, Rosenthal K, Wills RW.

J Vet Intern Med. 2018 Mar;32(2):658-664. doi: 10.1111/jvim.15039. Epub 2018 Feb 9.

12.

Interactive Journal Club: Teaching an Old Dog New Tricks.

Rosenthal J, Rosenthal KS.

J Med Educ Curric Dev. 2017 Jul 21;4:2382120517719710. doi: 10.1177/2382120517719710. eCollection 2017 Jan-Dec.

13.

Breastfeeding Behaviors and the Innate Immune System of Human Milk: Working Together to Protect Infants against Inflammation, HIV-1, and Other Infections.

Henrick BM, Yao XD, Nasser L, Roozrogousheh A, Rosenthal KL.

Front Immunol. 2017 Nov 29;8:1631. doi: 10.3389/fimmu.2017.01631. eCollection 2017. Review.

14.

A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.

Kroh HK, Chandrasekaran R, Zhang Z, Rosenthal K, Woods R, Jin X, Nyborg AC, Rainey GJ, Warrener P, Melnyk RA, Spiller BW, Lacy DB.

J Biol Chem. 2018 Jan 19;293(3):941-952. doi: 10.1074/jbc.M117.813428. Epub 2017 Nov 27.

15.

Enzyme-Based Electrobiotechnological Synthesis.

Schmitz LM, Rosenthal K, Lütz S.

Adv Biochem Eng Biotechnol. 2019;167:87-134. doi: 10.1007/10_2017_33.

PMID:
29134460
16.

Beyond the bulk: disclosing the life of single microbial cells.

Rosenthal K, Oehling V, Dusny C, Schmid A.

FEMS Microbiol Rev. 2017 Nov 1;41(6):751-780. doi: 10.1093/femsre/fux044. Review.

17.

Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.

Kroh HK, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi MD, Nyborg AC, Rainey GJ, Warrener P, Spiller BW, Lacy DB.

J Biol Chem. 2017 Sep 1;292(35):14401-14412. doi: 10.1074/jbc.M117.781112. Epub 2017 Jul 13.

18.

Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.

Tkaczyk C, Kasturirangan S, Minola A, Jones-Nelson O, Gunter V, Shi YY, Rosenthal K, Aleti V, Semenova E, Warrener P, Tabor D, Stover CK, Corti D, Rainey G, Sellman BR.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00629-17. doi: 10.1128/AAC.00629-17. Print 2017 Aug.

19.

An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritis.

Mikecz K, Glant TT, Markovics A, Rosenthal KS, Kurko J, Carambula RE, Cress S, Steiner HL Rd, Zimmerman DH.

Vaccine. 2017 Jul 13;35(32):4048-4056. doi: 10.1016/j.vaccine.2017.05.009. Epub 2017 Jun 3.

20.

Technique to avoid cortical entrapment in early insertion of capsular tension rings.

Rosenthal KJ.

J Cataract Refract Surg. 2017 Apr;43(4):577. doi: 10.1016/j.jcrs.2017.01.019. No abstract available.

PMID:
28532953
21.

LEAPS Vaccine Incorporating HER-2/neu Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread of Breast Cancer in a Mouse Model.

Rosenthal KS, Stone S, Koski G, Zimmerman DH.

J Immunol Res. 2017;2017:3613505. doi: 10.1155/2017/3613505. Epub 2017 Mar 26.

22.
23.

Insights into Soluble Toll-Like Receptor 2 as a Downregulator of Virally Induced Inflammation.

Henrick BM, Yao XD, Taha AY, German JB, Rosenthal KL.

Front Immunol. 2016 Aug 2;7:291. doi: 10.3389/fimmu.2016.00291. eCollection 2016. Review.

24.

Accessory renal arteries: Prevalence in resistant hypertension and an important role in nonresponse to radiofrequency renal denervation.

VonAchen P, Hamann J, Houghland T, Lesser JR, Wang Y, Caye D, Rosenthal K, Garberich RF, Daniels M, Schwartz RS.

Cardiovasc Revasc Med. 2016 Oct - Nov;17(7):470-473. doi: 10.1016/j.carrev.2016.07.009. Epub 2016 Jul 21.

PMID:
27493150
25.

Generation and Characterization of an IgG4 Monomeric Fc Platform.

Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V.

PLoS One. 2016 Aug 1;11(8):e0160345. doi: 10.1371/journal.pone.0160345. eCollection 2016.

26.

Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava.

Calicchio KW, Bennett RA, Laraio LC, Weisse C, Zwingenberger AL, Rosenthal KL, Johnston MS, Campbell VL, Solomon JA.

Am J Vet Res. 2016 May;77(5):540-7. doi: 10.2460/ajvr.77.5.540.

PMID:
27111022
27.

Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action.

Geoghegan JC, Diedrich G, Lu X, Rosenthal K, Sachsenmeier KF, Wu H, Dall'Acqua WF, Damschroder MM.

MAbs. 2016;8(3):454-67. doi: 10.1080/19420862.2016.1143182. Epub 2016 Feb 8.

28.

Intestinal Leiomyositis: A Cause of Chronic Intestinal Pseudo-Obstruction in 6 Dogs.

Zacuto AC, Pesavento PA, Hill S, McAlister A, Rosenthal K, Cherbinsky O, Marks SL.

J Vet Intern Med. 2016 Jan-Feb;30(1):132-40. doi: 10.1111/jvim.13652. Epub 2015 Nov 26.

29.

HIV-1 Structural Proteins Serve as PAMPs for TLR2 Heterodimers Significantly Increasing Infection and Innate Immune Activation.

Henrick BM, Yao XD, Rosenthal KL; INFANT study team.

Front Immunol. 2015 Aug 19;6:426. doi: 10.3389/fimmu.2015.00426. eCollection 2015.

30.

Anterior Chamber Iris Claw Lens for the Treatment of Aphakia in a Patient with Megalocornea.

Saffra N, Rakhamimov A, Masini R, Rosenthal KJ.

Case Rep Ophthalmol. 2015 Jun 2;6(2):164-9. doi: 10.1159/000431251. eCollection 2015 May-Aug.

31.

Novel chimpanzee adenovirus-vectored respiratory mucosal tuberculosis vaccine: overcoming local anti-human adenovirus immunity for potent TB protection.

Jeyanathan M, Thanthrige-Don N, Afkhami S, Lai R, Damjanovic D, Zganiacz A, Feng X, Yao XD, Rosenthal KL, Medina MF, Gauldie J, Ertl HC, Xing Z.

Mucosal Immunol. 2015 Nov;8(6):1373-87. doi: 10.1038/mi.2015.29. Epub 2015 Apr 15.

PMID:
25872483
32.

Rheumatoid arthritis vaccine therapies: perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis.

Rosenthal KS, Mikecz K, Steiner HL 3rd, Glant TT, Finnegan A, Carambula RE, Zimmerman DH.

Expert Rev Vaccines. 2015 Jun;14(6):891-908. doi: 10.1586/14760584.2015.1026330. Epub 2015 Mar 18. Review.

33.

S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo.

Chen B, Miller AL, Rebelatto M, Brewah Y, Rowe DC, Clarke L, Czapiga M, Rosenthal K, Imamichi T, Chen Y, Chang CS, Chowdhury PS, Naiman B, Wang Y, Yang D, Humbles AA, Herbst R, Sims GP.

PLoS One. 2015 Feb 23;10(2):e0115828. doi: 10.1371/journal.pone.0115828. eCollection 2015.

34.

Reply: To PMID 25135548.

Dewey S, Beiko G, Braga-Mela R, Nixon DR, Raviv T, Rosenthal K.

J Cataract Refract Surg. 2015 Feb;41(2):480. doi: 10.1016/j.jcrs.2014.12.037. No abstract available.

PMID:
25661154
35.

Coronary computed tomographic angiographic findings in patients with Kawasaki disease.

Han BK, Lesser A, Rosenthal K, Dummer K, Grant K, Newell M.

Am J Cardiol. 2014 Dec 1;114(11):1676-81. doi: 10.1016/j.amjcard.2014.09.004. Epub 2014 Sep 16.

PMID:
25307199
36.

Soluble toll-like receptor 2 is significantly elevated in HIV-1 infected breast milk and inhibits HIV-1 induced cellular activation, inflammation and infection.

Henrick BM, Yao XD, Drannik AG, Abimiku A, Rosenthal KL; INFANT Study Team.

AIDS. 2014 Sep 10;28(14):2023-32. doi: 10.1097/QAD.0000000000000381.

PMID:
25265071
37.

Microincisions in cataract surgery.

Dewey S, Beiko G, Braga-Mele R, Nixon DR, Raviv T, Rosenthal K; ASCRS Cataract Clinical Committee, Instrumentation and IOLs Subcommittee.

J Cataract Refract Surg. 2014 Sep;40(9):1549-57. doi: 10.1016/j.jcrs.2014.07.006. Review.

PMID:
25135548
38.

BRAF-Targeted Therapy to Treat Superior Vena Cava Syndrome in a Patient With Metastatic Cancer.

Mesko SM, Rosenthal KJ, Boasberg PD, Hamid O.

J Clin Oncol. 2015 Sep 1;33(25):e101-3. doi: 10.1200/JCO.2013.49.5622. Epub 2014 Apr 7. No abstract available.

PMID:
24711550
39.

Cardiovascular imaging trends in congenital heart disease: a single center experience.

Han BK, Lesser AM, Vezmar M, Rosenthal K, Rutten-Ramos S, Lindberg J, Caye D, Lesser JR.

J Cardiovasc Comput Tomogr. 2013 Nov-Dec;7(6):361-6. doi: 10.1016/j.jcct.2013.11.002. Epub 2013 Nov 8.

PMID:
24331931
40.

Non-sedated, free breathing cardiac CT for evaluation of complex congenital heart disease in neonates.

Han BK, Overman DM, Grant K, Rosenthal K, Rutten-Ramos S, Cook D, Lesser JR.

J Cardiovasc Comput Tomogr. 2013 Nov-Dec;7(6):354-60. doi: 10.1016/j.jcct.2013.11.006. Epub 2013 Nov 7.

PMID:
24331930
41.

November consultation #8.

Rosenthal KJ.

J Cataract Refract Surg. 2013 Nov;39(11):1786-7. doi: 10.1016/j.jcrs.2013.08.029. No abstract available.

PMID:
24160396
42.

Clinical and ultrasound biomicroscopic findings in a patient with anterior vaulting of a customized, flexible artificial iris.

Rosenthal KJ, Venkateswaran N.

J Refract Surg. 2013 Oct;29(10):663-4. doi: 10.3928/1081597X-20130919-01. No abstract available.

PMID:
24094308
43.

Acting locally: innate mucosal immunity in resistance to HIV-1 infection in Kenyan commercial sex workers.

Yao XD, Omange RW, Henrick BM, Lester RT, Kimani J, Ball TB, Plummer FA, Rosenthal KL.

Mucosal Immunol. 2014 Mar;7(2):268-79. doi: 10.1038/mi.2013.44. Epub 2013 Jun 26.

PMID:
23801306
44.

Antiviral activity of trappin-2 and elafin in vitro and in vivo against genital herpes.

Drannik AG, Nag K, Sallenave JM, Rosenthal KL.

J Virol. 2013 Jul;87(13):7526-38. doi: 10.1128/JVI.02243-12. Epub 2013 May 1.

45.

Aptamer-conjugated and doxorubicin-loaded unimolecular micelles for targeted therapy of prostate cancer.

Xu W, Siddiqui IA, Nihal M, Pilla S, Rosenthal K, Mukhtar H, Gong S.

Biomaterials. 2013 Jul;34(21):5244-53. doi: 10.1016/j.biomaterials.2013.03.006. Epub 2013 Apr 11.

46.

Concurrent treatment of chronic psoriasis and asthma with ustekinumab.

Amarnani A, Rosenthal KS, Mercado JM, Brodell RT.

J Dermatolog Treat. 2014 Feb;25(1):63-6. doi: 10.3109/09546634.2013.782095. Epub 2013 May 6.

PMID:
23469809
47.

LEAPS therapeutic vaccines as antigen specific suppressors of inflammation in infectious and autoimmune diseases.

Zimmerman DH, Steiner H 3rd, Carmabula R, Talor E, Rosenthal KS.

J Vaccines Vaccin. 2012 Sep 20;3(5). pii: 149.

48.

Extracellular ATP and Toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17.

Paustian C, Taylor P, Johnson T, Xu M, Ramirez N, Rosenthal KS, Shu S, Cohen PA, Czerniecki BJ, Koski GK.

PLoS One. 2013;8(1):e54804. doi: 10.1371/journal.pone.0054804. Epub 2013 Jan 31.

49.

Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells.

Drannik AG, Nag K, Yao XD, Henrick BM, Ball TB, Plummer FA, Wachihi C, Kimani J, Rosenthal KL.

PLoS One. 2012;7(12):e52738. doi: 10.1371/journal.pone.0052738. Epub 2012 Dec 27.

50.

Picoliter nDEP traps enable time-resolved contactless single bacterial cell analysis in controlled microenvironments.

Fritzsch FS, Rosenthal K, Kampert A, Howitz S, Dusny C, Blank LM, Schmid A.

Lab Chip. 2013 Feb 7;13(3):397-408. doi: 10.1039/c2lc41092c.

PMID:
23223864

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