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Items: 1 to 50 of 97

1.

Myosin IIA suppresses glioblastoma development in a mechanically sensitive manner.

Picariello HS, Kenchappa RS, Rai V, Crish JF, Dovas A, Pogoda K, McMahon M, Bell ES, Chandrasekharan U, Luu A, West R, Lammerding J, Canoll P, Odde DJ, Janmey PA, Egelhoff T, Rosenfeld SS.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15550-15559. doi: 10.1073/pnas.1902847116. Epub 2019 Jun 24.

PMID:
31235578
2.

Progress Toward Long-Term Survivors of Glioblastoma.

Cantrell JN, Waddle MR, Rotman M, Peterson JL, Ruiz-Garcia H, Heckman MG, Quiñones-Hinojosa A, Rosenfeld SS, Brown PD, Trifiletti DM.

Mayo Clin Proc. 2019 Jul;94(7):1278-1286. doi: 10.1016/j.mayocp.2018.11.031. Epub 2019 Jun 20.

PMID:
31230743
3.

Potential influence of IDH1 mutation and MGMT gene promoter methylation on glioma-related preoperative seizures and postoperative seizure control.

Feyissa AM, Worrell GA, Tatum WO, Chaichana KL, Jentoft ME, Guerrero Cazares H, Ertekin-Taner N, Rosenfeld SS, ReFaey K, Quinones-Hinojosa A.

Seizure. 2019 Jul;69:283-289. doi: 10.1016/j.seizure.2019.05.018. Epub 2019 May 20.

PMID:
31141785
4.

Survival trends in glioblastoma and association with treating facility volume.

Aulakh S, DeDeo MR, Free J, Rosenfeld SS, Quinones-Hinojosa A, Paulus A, Manna A, Manochakian R, Chanan-Khan AA, Ailawadhi S.

J Clin Neurosci. 2019 Oct;68:271-274. doi: 10.1016/j.jocn.2019.04.028. Epub 2019 May 24.

PMID:
31133366
5.

A Brownian dynamics tumor progression simulator with application to glioblastoma.

Klank RL, Rosenfeld SS, Odde DJ.

Converg Sci Phys Oncol. 2018 Mar;4(1). pii: 015001. doi: 10.1088/2057-1739/aa9e6e. Epub 2018 Jan 3.

6.

Microtubule-Based Control of Motor-Clutch System Mechanics in Glioma Cell Migration.

Prahl LS, Bangasser PF, Stopfer LE, Hemmat M, White FM, Rosenfeld SS, Odde DJ.

Cell Rep. 2018 Nov 27;25(9):2591-2604.e8. doi: 10.1016/j.celrep.2018.10.101.

7.

National care among patients with WHO grade I intracranial meningioma.

Dutta SW, Peterson JL, Vallow LA, Mahajan A, Rosenfeld SS, Quiñones-Hinojosa A, Trifiletti DM.

J Clin Neurosci. 2018 Sep;55:17-24. doi: 10.1016/j.jocn.2018.06.026. Epub 2018 Jun 15.

PMID:
29910033
8.

High-frequency oscillations in awake patients undergoing brain tumor-related epilepsy surgery.

Feyissa AM, Worrell GA, Tatum WO, Mahato D, Brinkmann BH, Rosenfeld SS, ReFaey K, Bechtle PS, Quinones-Hinojosa A.

Neurology. 2018 Mar 27;90(13):e1119-e1125. doi: 10.1212/WNL.0000000000005216. Epub 2018 Feb 28.

9.

A posttranslational modification of the mitotic kinesin Eg5 that enhances its mechanochemical coupling and alters its mitotic function.

Muretta JM, Reddy BJN, Scarabelli G, Thompson AF, Jariwala S, Major J, Venere M, Rich JN, Willard B, Thomas DD, Stumpff J, Grant BJ, Gross SP, Rosenfeld SS.

Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1779-E1788. doi: 10.1073/pnas.1718290115. Epub 2018 Feb 5. Erratum in: Proc Natl Acad Sci U S A. 2018 Mar 5;:.

10.

The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry.

Atherton J, Yu IM, Cook A, Muretta JM, Joseph A, Major J, Sourigues Y, Clause J, Topf M, Rosenfeld SS, Houdusse A, Moores CA.

Elife. 2017 Aug 11;6. pii: e27793. doi: 10.7554/eLife.27793.

11.

Shifting the optimal stiffness for cell migration.

Bangasser BL, Shamsan GA, Chan CE, Opoku KN, Tüzel E, Schlichtmann BW, Kasim JA, Fuller BJ, McCullough BR, Rosenfeld SS, Odde DJ.

Nat Commun. 2017 May 22;8:15313. doi: 10.1038/ncomms15313.

12.

Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level.

Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ.

Cell Rep. 2017 Apr 18;19(3):668. doi: 10.1016/j.celrep.2017.03.074. No abstract available.

13.

Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level.

Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ.

Cell Rep. 2017 Jan 3;18(1):23-31. doi: 10.1016/j.celrep.2016.12.024. Erratum in: Cell Rep. 2017 Apr 18;19(3):668.

14.

Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype.

Southern BD, Grove LM, Rahaman SO, Abraham S, Scheraga RG, Niese KA, Sun H, Herzog EL, Liu F, Tschumperlin DJ, Egelhoff TT, Rosenfeld SS, Olman MA.

J Biol Chem. 2016 Mar 18;291(12):6083-95. doi: 10.1074/jbc.M115.712380. Epub 2016 Jan 13.

15.

The structural kinetics of switch-1 and the neck linker explain the functions of kinesin-1 and Eg5.

Muretta JM, Jun Y, Gross SP, Major J, Thomas DD, Rosenfeld SS.

Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):E6606-13. doi: 10.1073/pnas.1512305112. Epub 2015 Nov 16.

16.

The mitotic kinesin KIF11 is a driver of invasion, proliferation, and self-renewal in glioblastoma.

Venere M, Horbinski C, Crish JF, Jin X, Vasanji A, Major J, Burrows AC, Chang C, Prokop J, Wu Q, Sims PA, Canoll P, Summers MK, Rosenfeld SS, Rich JN.

Sci Transl Med. 2015 Sep 9;7(304):304ra143. doi: 10.1126/scitranslmed.aac6762.

17.

Multicenter phase 2 study of patupilone for recurrent or progressive brain metastases from non-small cell lung cancer.

Nayak L, DeAngelis LM, Robins HI, Govindan R, Gadgeel S, Kelly K, Rigas JR, Peereboom DM, Rosenfeld SS, Muzikansky A, Zheng M, Urban P, Abrey LE, Omuro A, Wen PY.

Cancer. 2015 Dec 1;121(23):4165-72. doi: 10.1002/cncr.29636. Epub 2015 Aug 26.

18.

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins.

Atherton J, Farabella I, Yu IM, Rosenfeld SS, Houdusse A, Topf M, Moores CA.

Elife. 2014 Sep 10;3:e03680. doi: 10.7554/eLife.03680.

19.

Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010.

Gittleman HR, Ostrom QT, Rouse CD, Dowling JA, de Blank PM, Kruchko CA, Elder JB, Rosenfeld SS, Selman WR, Sloan AE, Barnholtz-Sloan JS.

Cancer. 2015 Jan 1;121(1):102-12. doi: 10.1002/cncr.29015. Epub 2014 Aug 25.

20.

Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family.

Goulet A, Major J, Jun Y, Gross SP, Rosenfeld SS, Moores CA.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1837-42. doi: 10.1073/pnas.1319848111. Epub 2014 Jan 21.

21.

Oculomotor nerve palsy as the presenting symptom of gummatous neurosyphilis and human immunodeficiency virus infection: clinical response to treatment.

Hess CW, Rosenfeld SS, Resor SR Jr.

JAMA Neurol. 2013 Dec;70(12):1582-3. doi: 10.1001/jamaneurol.2013.1485. No abstract available.

PMID:
24322513
22.

Loop L5 assumes three distinct orientations during the ATPase cycle of the mitotic kinesin Eg5: a transient and time-resolved fluorescence study.

Muretta JM, Behnke-Parks WM, Major J, Petersen KJ, Goulet A, Moores CA, Thomas DD, Rosenfeld SS.

J Biol Chem. 2013 Nov 29;288(48):34839-49. doi: 10.1074/jbc.M113.518845. Epub 2013 Oct 21.

23.

Determinants of maximal force transmission in a motor-clutch model of cell traction in a compliant microenvironment.

Bangasser BL, Rosenfeld SS, Odde DJ.

Biophys J. 2013 Aug 6;105(3):581-92. doi: 10.1016/j.bpj.2013.06.027.

24.

"Snapshots" of ispinesib-induced conformational changes in the mitotic kinesin Eg5.

Kaan HY, Major J, Tkocz K, Kozielski F, Rosenfeld SS.

J Biol Chem. 2013 Jun 21;288(25):18588-98. doi: 10.1074/jbc.M113.462648. Epub 2013 May 8.

25.

The structural basis of force generation by the mitotic motor kinesin-5.

Goulet A, Behnke-Parks WM, Sindelar CV, Major J, Rosenfeld SS, Moores CA.

J Biol Chem. 2012 Dec 28;287(53):44654-66. doi: 10.1074/jbc.M112.404228. Epub 2012 Nov 7.

26.

The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastoma.

D'Amico R, Lei L, Kennedy BC, Sisti J, Ebiana V, Crisman C, Christensen JG, Gil O, Rosenfeld SS, Canoll P, Bruce JN.

Neurol Res. 2012 Apr;34(3):252-61. doi: 10.1179/1743132812Y.0000000005. Epub 2012 Mar 5.

27.

Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens.

Ivkovic S, Beadle C, Noticewala S, Massey SC, Swanson KR, Toro LN, Bresnick AR, Canoll P, Rosenfeld SS.

Mol Biol Cell. 2012 Feb;23(4):533-42. doi: 10.1091/mbc.E11-01-0039. Epub 2012 Jan 4.

28.

A universal pathway for kinesin stepping.

Clancy BE, Behnke-Parks WM, Andreasson JO, Rosenfeld SS, Block SM.

Nat Struct Mol Biol. 2011 Aug 14;18(9):1020-7. doi: 10.1038/nsmb.2104.

29.

Regression of recurrent malignant gliomas with convection-enhanced delivery of topotecan.

Bruce JN, Fine RL, Canoll P, Yun J, Kennedy BC, Rosenfeld SS, Sands SA, Surapaneni K, Lai R, Yanes CL, Bagiella E, DeLaPaz RL.

Neurosurgery. 2011 Dec;69(6):1272-9; discussion 1279-80. doi: 10.1227/NEU.0b013e3182233e24.

30.

Loop L5 acts as a conformational latch in the mitotic kinesin Eg5.

Behnke-Parks WM, Vendome J, Honig B, Maliga Z, Moores C, Rosenfeld SS.

J Biol Chem. 2011 Feb 18;286(7):5242-53. doi: 10.1074/jbc.M110.192930. Epub 2010 Dec 9.

31.

The ATPase cycle of the mitotic motor CENP-E.

Rosenfeld SS, van Duffelen M, Behnke-Parks WM, Beadle C, Corrreia J, Xing J.

J Biol Chem. 2009 Nov 20;284(47):32858-68. doi: 10.1074/jbc.M109.041210. Epub 2009 Sep 16.

32.

Why kinesin is so processive.

Toprak E, Yildiz A, Hoffman MT, Rosenfeld SS, Selvin PR.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12717-22. doi: 10.1073/pnas.0808396106. Epub 2009 Jul 15.

33.

The role of myosin II in glioma invasion of the brain.

Beadle C, Assanah MC, Monzo P, Vallee R, Rosenfeld SS, Canoll P.

Mol Biol Cell. 2008 Aug;19(8):3357-68. doi: 10.1091/mbc.E08-03-0319. Epub 2008 May 21.

34.

The mitotic kinesin CENP-E is a processive transport motor.

Yardimci H, van Duffelen M, Mao Y, Rosenfeld SS, Selvin PR.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6016-21. doi: 10.1073/pnas.0711314105. Epub 2008 Apr 21.

35.

Myelosuppression in patients benefiting from imatinib with hydroxyurea for recurrent malignant gliomas.

Shah GD, Silver JS, Rosenfeld SS, Gavrilovic IT, Abrey LE, Lassman AB.

J Neurooncol. 2007 Nov;85(2):217-22. Epub 2007 Jun 27.

PMID:
17594055
36.

How myosin VI coordinates its heads during processive movement.

Sweeney HL, Park H, Zong AB, Yang Z, Selvin PR, Rosenfeld SS.

EMBO J. 2007 Jun 6;26(11):2682-92. Epub 2007 May 17.

37.

Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma.

Nabors LB, Mikkelsen T, Rosenfeld SS, Hochberg F, Akella NS, Fisher JD, Cloud GA, Zhang Y, Carson K, Wittemer SM, Colevas AD, Grossman SA.

J Clin Oncol. 2007 May 1;25(13):1651-7.

38.

A pathway of structural changes produced by monastrol binding to Eg5.

Maliga Z, Xing J, Cheung H, Juszczak LJ, Friedman JM, Rosenfeld SS.

J Biol Chem. 2006 Mar 24;281(12):7977-82. Epub 2006 Jan 23.

39.

Central nervous system cancers: Clinical Practice Guidelines in Oncology.

Brem SS, Bierman PJ, Black P, Blumenthal DT, Brem H, Chamberlain MC, Chiocca EA, DeAngelis LM, Fenstermaker RA, Fine HA, Friedman A, Glass J, Grossman SA, Heimberger AB, Junck L, Levin V, Loeffler JJ, Maor MH, Narayana A, Newton HB, Olivi A, Portnow J, Prados M, Raizer JJ, Rosenfeld SS, Shrieve DC, Sills AK Jr, Spence AM, Vrionis FD; National Comprehensive Cancer Network.

J Natl Compr Canc Netw. 2005 Sep;3(5):644-90. No abstract available.

PMID:
16194456
40.

Docking and rolling, a model of how the mitotic motor Eg5 works.

Rosenfeld SS, Xing J, Jefferson GM, King PH.

J Biol Chem. 2005 Oct 21;280(42):35684-95. Epub 2005 Aug 22.

41.

Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains.

Höök P, Mikami A, Shafer B, Chait BT, Rosenfeld SS, Vallee RB.

J Biol Chem. 2005 Sep 23;280(38):33045-54. Epub 2005 Jul 18.

42.

Magnesium regulates ADP dissociation from myosin V.

Rosenfeld SS, Houdusse A, Sweeney HL.

J Biol Chem. 2005 Feb 18;280(7):6072-9. Epub 2004 Dec 4.

43.

A model of myosin V processivity.

Rosenfeld SS, Sweeney HL.

J Biol Chem. 2004 Sep 17;279(38):40100-11. Epub 2004 Jul 14.

44.

Myosin IIb is unconventionally conventional.

Rosenfeld SS, Xing J, Chen LQ, Sweeney HL.

J Biol Chem. 2003 Jul 25;278(30):27449-55. Epub 2003 May 11.

45.

Stepping and stretching. How kinesin uses internal strain to walk processively.

Rosenfeld SS, Fordyce PM, Jefferson GM, King PH, Block SM.

J Biol Chem. 2003 May 16;278(20):18550-6. Epub 2003 Mar 6.

46.

Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization.

Aslan M, Ryan TM, Townes TM, Coward L, Kirk MC, Barnes S, Alexander CB, Rosenfeld SS, Freeman BA.

J Biol Chem. 2003 Feb 7;278(6):4194-204. Epub 2002 Oct 24.

47.

Mechanism of regulation of Acanthamoeba myosin-IC by heavy-chain phosphorylation.

Ostap EM, Lin T, Rosenfeld SS, Tang N.

Biochemistry. 2002 Oct 15;41(41):12450-6.

PMID:
12369835
48.

Measuring kinesin's first step.

Rosenfeld SS, Xing J, Jefferson GM, Cheung HC, King PH.

J Biol Chem. 2002 Sep 27;277(39):36731-9. Epub 2002 Jul 16.

49.

The kinetic mechanism of Myo1e (human myosin-IC).

El Mezgueldi M, Tang N, Rosenfeld SS, Ostap EM.

J Biol Chem. 2002 Jun 14;277(24):21514-21. Epub 2002 Apr 8.

50.

ATP reorients the neck linker of kinesin in two sequential steps.

Rosenfeld SS, Jefferson GM, King PH.

J Biol Chem. 2001 Oct 26;276(43):40167-74. Epub 2001 Aug 16.

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