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Items: 1 to 50 of 53

1.

Lung disease in STAT3 hyper-IgE syndrome requires intense therapy.

Kröner C, Neumann J, Ley-Zaporozhan J, Hagl B, Meixner I, Spielberger BD, Dückers G, Belohradsky BH, Niehues T, Borte M, Rosenecker J, Kappler M, Nährig S, Reu S, Griese M, Renner ED.

Allergy. 2019 Sep;74(9):1691-1702. doi: 10.1111/all.13753. Epub 2019 Apr 4.

PMID:
30793327
2.

Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis.

Guan S, Munder A, Hedtfeld S, Braubach P, Glage S, Zhang L, Lienenklaus S, Schultze A, Hasenpusch G, Garrels W, Stanke F, Miskey C, Johler SM, Kumar Y, Tümmler B, Rudolph C, Ivics Z, Rosenecker J.

Nat Nanotechnol. 2019 Mar;14(3):287-297. doi: 10.1038/s41565-018-0358-x. Epub 2019 Jan 28.

PMID:
30692673
3.

Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems.

Guan S, Rosenecker J.

Gene Ther. 2017 Mar;24(3):133-143. doi: 10.1038/gt.2017.5. Epub 2017 Jan 17. Review.

PMID:
28094775
4.

Nebulisation of IVT mRNA Complexes for Intrapulmonary Administration.

Johler SM, Rejman J, Guan S, Rosenecker J.

PLoS One. 2015 Sep 9;10(9):e0137504. doi: 10.1371/journal.pone.0137504. eCollection 2015.

5.

Cystic fibrosis transmembrane conductance regulator-mRNA delivery: a novel alternative for cystic fibrosis gene therapy.

Bangel-Ruland N, Tomczak K, Fernández Fernández E, Leier G, Leciejewski B, Rudolph C, Rosenecker J, Weber WM.

J Gene Med. 2013 Nov-Dec;15(11-12):414-26. doi: 10.1002/jgm.2748.

PMID:
24123772
6.

Lentiviral small hairpin RNA delivery reduces apical sodium channel activity in differentiated human airway epithelial cells.

Aarbiou J, Copreni E, Buijs-Offerman RM, van der Wegen P, Castellani S, Carbone A, Tilesi F, Fradiani P, Hiemstra PS, Yueksekdag G, Diana A, Rosenecker J, Ascenzioni F, Conese M, Scholte BJ.

J Gene Med. 2012 Dec;14(12):733-45. doi: 10.1002/jgm.2672.

PMID:
23074129
7.

Formation of solid lipid nanoparticle (SLN)-gene vector complexes for transfection of mammalian cells in vitro.

Rudolph C, Rosenecker J.

Cold Spring Harb Protoc. 2012 Mar 1;2012(3):357-60. doi: 10.1101/pdb.prot068122.

PMID:
22383641
8.

Characterization of Ku70(2)-NLS as bipartite nuclear localization sequence for non-viral gene delivery.

Matschke J, Bohla A, Maucksch C, Mittal R, Rudolph C, Rosenecker J.

PLoS One. 2012;7(2):e24615. doi: 10.1371/journal.pone.0024615. Epub 2012 Feb 8.

9.

Albert Uffenheimer: pediatrician and public health advocate before Nazi rule.

Autenrieth A, Thal W, Rosenecker J.

Isr Med Assoc J. 2011 May;13(5):270-2.

10.

Gene and cell therapy for cystic fibrosis: from bench to bedside.

Conese M, Ascenzioni F, Boyd AC, Coutelle C, De Fino I, De Smedt S, Rejman J, Rosenecker J, Schindelhauer D, Scholte BJ.

J Cyst Fibros. 2011 Jun;10 Suppl 2:S114-28. doi: 10.1016/S1569-1993(11)60017-9. Review.

11.

PEGylation improves nanoparticle formation and transfection efficiency of messenger RNA.

Uzgün S, Nica G, Pfeifer C, Bosinco M, Michaelis K, Lutz JF, Schneider M, Rosenecker J, Rudolph C.

Pharm Res. 2011 Sep;28(9):2223-32. doi: 10.1007/s11095-011-0464-z. Epub 2011 May 19.

PMID:
21594715
12.

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice.

Kormann MS, Hasenpusch G, Aneja MK, Nica G, Flemmer AW, Herber-Jonat S, Huppmann M, Mays LE, Illenyi M, Schams A, Griese M, Bittmann I, Handgretinger R, Hartl D, Rosenecker J, Rudolph C.

Nat Biotechnol. 2011 Feb;29(2):154-7. doi: 10.1038/nbt.1733. Epub 2011 Jan 9.

PMID:
21217696
13.

The long and winding road to clinical success in gene therapy.

Rosenecker J.

Curr Opin Mol Ther. 2010 Oct;12(5):507-8. Review. No abstract available.

PMID:
20931738
14.

Dynamics of magnetic particles in cylindrical Halbach array: implications for magnetic cell separation and drug targeting.

Babinec P, Krafcík A, Babincová M, Rosenecker J.

Med Biol Eng Comput. 2010 Aug;48(8):745-53. doi: 10.1007/s11517-010-0636-8. Epub 2010 Jun 2.

PMID:
20517710
15.

Repeated siRNA application is a precondition for successful mRNA gammaENaC knockdown in the murine airways.

Yueksekdag G, Drechsel M, Rössner M, Schmidt C, Kormann M, Illenyi MC, Rudolph C, Rosenecker J.

Eur J Pharm Biopharm. 2010 Aug;75(3):305-10. doi: 10.1016/j.ejpb.2010.04.005. Epub 2010 Apr 18.

PMID:
20403432
16.

Magnetofection: the use of magnetic nanoparticles for nucleic acid delivery.

Plank C, Rosenecker J.

Cold Spring Harb Protoc. 2009 Jun;2009(6):pdb.prot5230. doi: 10.1101/pdb.prot5230. No abstract available.

PMID:
20147188
17.

Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesium.

Rosenecker J, Naundorf S, Rudolph C.

Eur J Med Res. 2009 Jul 22;14(7):304-8.

18.

Recent advances in magnetofection and its potential to deliver siRNAs in vitro.

Mykhaylyk O, Zelphati O, Hammerschmid E, Anton M, Rosenecker J, Plank C.

Methods Mol Biol. 2009;487:111-46. doi: 10.1007/978-1-60327-547-7_6.

PMID:
19301645
19.

Current prospects for mRNA gene delivery.

Yamamoto A, Kormann M, Rosenecker J, Rudolph C.

Eur J Pharm Biopharm. 2009 Mar;71(3):484-9. doi: 10.1016/j.ejpb.2008.09.016. Epub 2008 Oct 10. Review.

PMID:
18948192
20.

siRNA delivery by magnetofection.

Mykhaylyk O, Zelphati O, Rosenecker J, Plank C.

Curr Opin Mol Ther. 2008 Oct;10(5):493-505. Review.

PMID:
18830925
21.

Epithelial sodium channel inhibition in primary human bronchial epithelia by transfected siRNA.

Caci E, Melani R, Pedemonte N, Yueksekdag G, Ravazzolo R, Rosenecker J, Galietta LJ, Zegarra-Moran O.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):211-6. doi: 10.1165/rcmb.2007-0456OC. Epub 2008 Aug 21.

PMID:
18723440
22.

Cell type differences in activity of the Streptomyces bacteriophage phiC31 integrase.

Maucksch C, Aneja MK, Hennen E, Bohla A, Hoffmann F, Elfinger M, Rosenecker J, Rudolph C.

Nucleic Acids Res. 2008 Oct;36(17):5462-71. doi: 10.1093/nar/gkn532. Epub 2008 Aug 21.

23.

Targeted delivery of magnetic aerosol droplets to the lung.

Dames P, Gleich B, Flemmer A, Hajek K, Seidl N, Wiekhorst F, Eberbeck D, Bittmann I, Bergemann C, Weyh T, Trahms L, Rosenecker J, Rudolph C.

Nat Nanotechnol. 2007 Aug;2(8):495-9. doi: 10.1038/nnano.2007.217. Epub 2007 Jul 22.

PMID:
18654347
24.

Thyroid hormone (T3)-modification of polyethyleneglycol (PEG)-polyethyleneimine (PEI) graft copolymers for improved gene delivery to hepatocytes.

Rudolph C, Sieverling N, Schillinger U, Lesina E, Plank C, Thünemann AF, Schönberger H, Rosenecker J.

Biomaterials. 2007 Apr;28(10):1900-11. Epub 2006 Dec 28.

PMID:
17196251
25.

Aerosol gene delivery to the murine lung is mouse strain dependent.

Dames P, Ortiz A, Schillinger U, Lesina E, Plank C, Rosenecker J, Rudolph C.

J Mol Med (Berl). 2007 Apr;85(4):371-8. Epub 2006 Dec 8.

PMID:
17160403
26.

Gene therapy for cystic fibrosis lung disease: current status and future perspectives.

Rosenecker J, Huth S, Rudolph C.

Curr Opin Mol Ther. 2006 Oct;8(5):439-45. Review.

PMID:
17078386
27.

Interaction of polyamine gene vectors with RNA leads to the dissociation of plasmid DNA-carrier complexes.

Huth S, Hoffmann F, von Gersdorff K, Laner A, Reinhardt D, Rosenecker J, Rudolph C.

J Gene Med. 2006 Dec;8(12):1416-24.

PMID:
17029296
28.

Posaconazole for treatment of refractory invasive fungal disease.

Notheis G, Tarani L, Costantino F, Jansson A, Rosenecker J, Friederici D, Belohradsky BH, Reinhardt D, Seger R, Schweinitz DV, Wintergerst U.

Mycoses. 2006;49 Suppl 1:37-41.

PMID:
16961581
29.

Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers.

Weiss SI, Sieverling N, Niclasen M, Maucksch C, Thünemann AF, Möhwald H, Reinhardt D, Rosenecker J, Rudolph C.

Biomaterials. 2006 Apr;27(10):2302-12. Epub 2005 Dec 6.

PMID:
16337267
30.

Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium.

Rudolph C, Schillinger U, Ortiz A, Plank C, Golas MM, Sander B, Stark H, Rosenecker J.

Mol Ther. 2005 Sep;12(3):493-501.

31.

Methodological optimization of polyethylenimine (PEI)-based gene delivery to the lungs of mice via aerosol application.

Rudolph C, Ortiz A, Schillinger U, Jauernig J, Plank C, Rosenecker J.

J Gene Med. 2005 Jan;7(1):59-66.

PMID:
15538727
32.

Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo.

Rudolph C, Schillinger U, Ortiz A, Tabatt K, Plank C, Müller RH, Rosenecker J.

Pharm Res. 2004 Sep;21(9):1662-9.

PMID:
15497694
33.

Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei.

Zink D, Amaral MD, Englmann A, Lang S, Clarke LA, Rudolph C, Alt F, Luther K, Braz C, Sadoni N, Rosenecker J, Schindelhauer D.

J Cell Biol. 2004 Sep 13;166(6):815-25.

34.

Insights into the mechanism of magnetofection using PEI-based magnetofectins for gene transfer.

Huth S, Lausier J, Gersting SW, Rudolph C, Plank C, Welsch U, Rosenecker J.

J Gene Med. 2004 Aug;6(8):923-36.

PMID:
15293351
35.

Gene delivery to respiratory epithelial cells by magnetofection.

Gersting SW, Schillinger U, Lausier J, Nicklaus P, Rudolph C, Plank C, Reinhardt D, Rosenecker J.

J Gene Med. 2004 Aug;6(8):913-22.

PMID:
15293350
36.

A novel transfecting peptide comprising a tetrameric nuclear localization sequence.

Ritter W, Plank C, Lausier J, Rudolph C, Zink D, Reinhardt D, Rosenecker J.

J Mol Med (Berl). 2003 Nov;81(11):708-17. Epub 2003 Oct 22.

PMID:
14574456
37.

Enhancing and targeting nucleic acid delivery by magnetic force.

Plank C, Anton M, Rudolph C, Rosenecker J, Krötz F.

Expert Opin Biol Ther. 2003 Aug;3(5):745-58. Review.

PMID:
12880375
38.

The magnetofection method: using magnetic force to enhance gene delivery.

Plank C, Schillinger U, Scherer F, Bergemann C, Rémy JS, Krötz F, Anton M, Lausier J, Rosenecker J.

Biol Chem. 2003 May;384(5):737-47. Review.

PMID:
12817470
39.

Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells.

Rudolph C, Plank C, Lausier J, Schillinger U, Müller RH, Rosenecker J.

J Biol Chem. 2003 Mar 28;278(13):11411-8. Epub 2003 Jan 8.

40.

Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: analysing the role of proteins and glycoproteins.

Rosenecker J, Naundorf S, Gersting SW, Hauck RW, Gessner A, Nicklaus P, Müller RH, Rudolph C.

J Gene Med. 2003 Jan;5(1):49-60.

PMID:
12516051
41.

Nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.

Rudolph C, Schillinger U, Plank C, Gessner A, Nicklaus P, Müller R, Rosenecker J.

Biochim Biophys Acta. 2002 Oct 10;1573(1):75-83.

PMID:
12383945
42.

Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency.

Rudolph C, Müller RH, Rosenecker J.

J Gene Med. 2002 Jan-Feb;4(1):66-74.

PMID:
11828389
43.

Diabetes mellitus and cystic fibrosis: comparison of clinical parameters in patients treated with insulin versus oral glucose-lowering agents.

Rosenecker J, Eichler I, Bärmeier H, von der Hardt H.

Pediatr Pulmonol. 2001 Nov;32(5):351-5.

PMID:
11596159
44.

Diabetes mellitus in patients with cystic fibrosis: the impact of diabetes mellitus on pulmonary function and clinical outcome.

Rosenecker J, Höfler R, Steinkamp G, Eichler I, Smaczny C, Ballmann M, Posselt HG, Bargon J, von der Hardt H.

Eur J Med Res. 2001 Aug 27;6(8):345-50.

PMID:
11549516
46.

In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers.

Rudolph C, Lausier J, Naundorf S, Müller RH, Rosenecker J.

J Gene Med. 2000 Jul-Aug;2(4):269-78.

PMID:
10953918
47.

Interaction of liposomal and polycationic transfection complexes with pulmonary surfactant.

Ernst N, Ulrichskötter S, Schmalix WA, Rädler J, Galneder R, Mayer E, Gersting S, Plank C, Reinhardt D, Rosenecker J.

J Gene Med. 1999 Sep-Oct;1(5):331-40.

PMID:
10738550
48.

Specific and rapid detection by fluorescent in situ hybridization of bacteria in clinical samples obtained from cystic fibrosis patients.

Hogardt M, Trebesius K, Geiger AM, Hornef M, Rosenecker J, Heesemann J.

J Clin Microbiol. 2000 Feb;38(2):818-25.

49.

Towards gene therapy of cystic fibrosis.

Rosenecker J, Schmalix WA, Schindelhauer D, Plank C, Reinhardt D.

Eur J Med Res. 1998 Mar 23;3(3):149-56. Review.

PMID:
9502755
50.

Increased liposome extravasation in selected tissues: effect of substance P.

Rosenecker J, Zhang W, Hong K, Lausier J, Geppetti P, Yoshihara S, Papahadjopoulos D, Nadel JA.

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7236-41.

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