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Items: 1 to 50 of 51

1.

Adoptive Regulatory T Cell Therapy in a Patient with Systemic Lupus Erythematosus.

Dall'Era M, Pauli ML, Remedios K, Taravati K, Sandoval PM, Putnam AL, Lares A, Haemel A, Tang Q, Hellerstein M, Fitch M, McNamara J, Welch B, Bluestone JA, Wofsy D, Rosenblum MD; Autoimmunity Centers of Excellence.

Arthritis Rheumatol. 2018 Oct 1. doi: 10.1002/art.40737. [Epub ahead of print]

PMID:
30277008
2.

Colitis interruptus: LAGing gut inflammation.

Mehta P, Rosenblum MD.

Sci Immunol. 2018 Sep 7;3(27). pii: eaav0447. doi: 10.1126/sciimmunol.aav0447.

PMID:
30194243
3.

Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization.

Chang HW, Yan D, Singh R, Liu J, Lu X, Ucmak D, Lee K, Afifi L, Fadrosh D, Leech J, Vasquez KS, Lowe MM, Rosenblum MD, Scharschmidt TC, Lynch SV, Liao W.

Microbiome. 2018 Sep 5;6(1):154. doi: 10.1186/s40168-018-0533-1.

4.

RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways.

Ahn R, Yan D, Chang HW, Lee K, Bhattarai S, Huang ZM, Nakamura M, Singh R, Afifi L, Taravati K, Munoz-Sandoval P, Pauli M, Rosenblum MD, Liao W.

Sci Rep. 2018 Jul 27;8(1):11368. doi: 10.1038/s41598-018-29472-w.

5.

A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.

Barry KC, Hsu J, Broz ML, Cueto FJ, Binnewies M, Combes AJ, Nelson AE, Loo K, Kumar R, Rosenblum MD, Alvarado MD, Wolf DM, Bogunovic D, Bhardwaj N, Daud AI, Ha PK, Ryan WR, Pollack JL, Samad B, Asthana S, Chan V, Krummel MF.

Nat Med. 2018 Aug;24(8):1178-1191. doi: 10.1038/s41591-018-0085-8. Epub 2018 Jun 25.

PMID:
29942093
6.

Targeting EZH2 Reprograms Intratumoral Regulatory T Cells to Enhance Cancer Immunity.

Wang D, Quiros J, Mahuron K, Pai CC, Ranzani V, Young A, Silveria S, Harwin T, Abnousian A, Pagani M, Rosenblum MD, Van Gool F, Fong L, Bluestone JA, DuPage M.

Cell Rep. 2018 Jun 12;23(11):3262-3274. doi: 10.1016/j.celrep.2018.05.050.

7.

Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.

Mande P, Zirak B, Ko WC, Taravati K, Bride KL, Brodeur TY, Deng A, Dresser K, Jiang Z, Ettinger R, Fitzgerald KA, Rosenblum MD, Harris JE, Marshak-Rothstein A.

J Clin Invest. 2018 Jul 2;128(7):2966-2978. doi: 10.1172/JCI98219. Epub 2018 Jun 11.

8.

Say it isn't pso: IL-25 drives skin inflammation.

Kalekar LA, Rosenblum MD.

Sci Immunol. 2018 May 4;3(23). pii: eaat9662. doi: 10.1126/sciimmunol.aat9662.

PMID:
29728428
9.

Skin-Resident T Cells Drive Dermal Dendritic Cell Migration in Response to Tissue Self-Antigen.

Ali N, Zirak B, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD.

J Immunol. 2018 May 1;200(9):3100-3108. doi: 10.4049/jimmunol.1701206. Epub 2018 Mar 21.

PMID:
29563179
10.

HDAC inhibition potentiates immunotherapy in triple negative breast cancer.

Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN.

Oncotarget. 2017 Dec 12;8(69):114156-114172. doi: 10.18632/oncotarget.23169. eCollection 2017 Dec 26.

11.

SJS/TEN 2017: Building Multidisciplinary Networks to Drive Science and Translation.

White KD, Abe R, Ardern-Jones M, Beachkofsky T, Bouchard C, Carleton B, Chodosh J, Cibotti R, Davis R, Denny JC, Dodiuk-Gad RP, Ergen EN, Goldman JL, Holmes JH 4th, Hung SI, Lacouture ME, Lehloenya RJ, Mallal S, Manolio TA, Micheletti RG, Mitchell CM, Mockenhaupt M, Ostrov DA, Pavlos R, Pirmohamed M, Pope E, Redwood A, Rosenbach M, Rosenblum MD, Roujeau JC, Saavedra AP, Saeed HN, Struewing JP, Sueki H, Sukasem C, Sung C, Trubiano JA, Weintraub J, Wheatley LM, Williams KB, Worley B, Chung WH, Shear NH, Phillips EJ.

J Allergy Clin Immunol Pract. 2018 Jan - Feb;6(1):38-69. doi: 10.1016/j.jaip.2017.11.023. Review.

PMID:
29310768
12.

Genomic analysis of atypical fibroxanthoma.

Lai K, Harwood CA, Purdie KJ, Proby CM, Leigh IM, Ravi N, Mully TW, Brooks L, Sandoval PM, Rosenblum MD, Arron ST.

PLoS One. 2017 Nov 15;12(11):e0188272. doi: 10.1371/journal.pone.0188272. eCollection 2017.

13.

Injectable Polymeric Cytokine-Binding Nanowires Are Effective Tissue-Specific Immunomodulators.

Zamecnik CR, Lowe MM, Patterson DM, Rosenblum MD, Desai TA.

ACS Nano. 2017 Nov 28;11(11):11433-11440. doi: 10.1021/acsnano.7b06094. Epub 2017 Nov 15.

14.

Partially exhausted tumor-infiltrating lymphocytes predict response to combination immunotherapy.

Loo K, Tsai KK, Mahuron K, Liu J, Pauli ML, Sandoval PM, Nosrati A, Lee J, Chen L, Hwang J, Levine LS, Krummel MF, Algazi AP, Pampaloni M, Alvarado MD, Rosenblum MD, Daud AI.

JCI Insight. 2017 Jul 20;2(14). pii: 93433. doi: 10.1172/jci.insight.93433. [Epub ahead of print]

15.

Regulatory T cells in skin.

Ali N, Rosenblum MD.

Immunology. 2017 Nov;152(3):372-381. doi: 10.1111/imm.12791. Epub 2017 Aug 4. Review.

PMID:
28699278
16.

Skin-infiltrating, interleukin-22-producing T cells differentiate pediatric psoriasis from adult psoriasis.

Cordoro KM, Hitraya-Low M, Taravati K, Sandoval PM, Kim E, Sugarman J, Pauli ML, Liao W, Rosenblum MD.

J Am Acad Dermatol. 2017 Sep;77(3):417-424. doi: 10.1016/j.jaad.2017.05.017. Epub 2017 Jun 16.

PMID:
28624119
17.

Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.

Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD.

Cell. 2017 Jun 1;169(6):1119-1129.e11. doi: 10.1016/j.cell.2017.05.002. Epub 2017 May 25.

18.

Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.

Scharschmidt TC, Vasquez KS, Pauli ML, Leitner EG, Chu K, Truong HA, Lowe MM, Sanchez Rodriguez R, Ali N, Laszik ZG, Sonnenburg JL, Millar SE, Rosenblum MD.

Cell Host Microbe. 2017 Apr 12;21(4):467-477.e5. doi: 10.1016/j.chom.2017.03.001. Epub 2017 Mar 23.

19.

Warfarin-Associated Nonuremic Calciphylaxis.

Yu WY, Bhutani T, Kornik R, Pincus LB, Mauro T, Rosenblum MD, Fox LP.

JAMA Dermatol. 2017 Mar 1;153(3):309-314. doi: 10.1001/jamadermatol.2016.4821. Review.

20.

Response to Interleukin (IL)-17 Inhibition in an Adolescent With Severe Manifestations of IL-36 Receptor Antagonist Deficiency (DITRA).

Cordoro KM, Ucmak D, Hitraya-Low M, Rosenblum MD, Liao W.

JAMA Dermatol. 2017 Jan 1;153(1):106-108. doi: 10.1001/jamadermatol.2016.3490. No abstract available.

PMID:
27760239
21.

Tumor immune profiling predicts response to anti-PD-1 therapy in human melanoma.

Daud AI, Loo K, Pauli ML, Sanchez-Rodriguez R, Sandoval PM, Taravati K, Tsai K, Nosrati A, Nardo L, Alvarado MD, Algazi AP, Pampaloni MH, Lobach IV, Hwang J, Pierce RH, Gratz IK, Krummel MF, Rosenblum MD.

J Clin Invest. 2016 Sep 1;126(9):3447-52. doi: 10.1172/JCI87324. Epub 2016 Aug 15.

22.

Plasmacytoid dendritic cells (pDCs) and regulatory T (Treg) cells may be the key to viral reactivation in drug-induced hypersensitivity syndrome (DIHS).

Chen YC, Rosenblum MD, Shinkai K.

J Am Acad Dermatol. 2016 Jun;74(6):1288-9. doi: 10.1016/j.jaad.2015.11.031. No abstract available.

PMID:
27185444
23.

Cutting Edge: Regulatory T Cells Facilitate Cutaneous Wound Healing.

Nosbaum A, Prevel N, Truong HA, Mehta P, Ettinger M, Scharschmidt TC, Ali NH, Pauli ML, Abbas AK, Rosenblum MD.

J Immunol. 2016 Mar 1;196(5):2010-4. doi: 10.4049/jimmunol.1502139. Epub 2016 Jan 29.

24.

The distribution of cutaneous metastases correlates with local immunologic milieu.

Schulman JM, Pauli ML, Neuhaus IM, Sanchez Rodriguez R, Taravati K, Shin US, McCalmont TH, Rosenblum MD.

J Am Acad Dermatol. 2016 Mar;74(3):470-6. doi: 10.1016/j.jaad.2015.10.012. Epub 2016 Jan 9.

25.

Regulatory T cell memory.

Rosenblum MD, Way SS, Abbas AK.

Nat Rev Immunol. 2016 Feb;16(2):90-101. doi: 10.1038/nri.2015.1. Epub 2015 Dec 21. Review.

26.

A Wave of Regulatory T Cells into Neonatal Skin Mediates Tolerance to Commensal Microbes.

Scharschmidt TC, Vasquez KS, Truong HA, Gearty SV, Pauli ML, Nosbaum A, Gratz IK, Otto M, Moon JJ, Liese J, Abbas AK, Fischbach MA, Rosenblum MD.

Immunity. 2015 Nov 17;43(5):1011-21. doi: 10.1016/j.immuni.2015.10.016.

27.

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis.

Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, Kwok PY, Hicks J, Jones KD, Penney S, Jhangiani SN, Rosenblum MD, Dell SD, Waterfield MR, Papa FR, Muzny DM, Zaitlen N, Leal SM, Gonzaga-Jauregui C; Baylor-Hopkins Center for Mendelian Genomics, Boerwinkle E, Eissa NT, Gibbs RA, Lupski JR, Orange JS, Shum AK.

Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20.

28.

Mechanisms of human autoimmunity.

Rosenblum MD, Remedios KA, Abbas AK.

J Clin Invest. 2015 Jun;125(6):2228-33. doi: 10.1172/JCI78088. Epub 2015 Jun 1. Review.

29.

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF.

Cancer Cell. 2014 Dec 8;26(6):938. doi: 10.1016/j.ccell.2014.11.010. Epub 2014 Dec 8. No abstract available.

30.

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity.

Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF.

Cancer Cell. 2014 Nov 10;26(5):638-52. doi: 10.1016/j.ccell.2014.09.007. Epub 2014 Oct 16.

31.

Melanoma immunotherapy.

Sanlorenzo M, Vujic I, Posch C, Dajee A, Yen A, Kim S, Ashworth M, Rosenblum MD, Algazi A, Osella-Abate S, Quaglino P, Daud A, Ortiz-Urda S.

Cancer Biol Ther. 2014 Jun 1;15(6):665-74. doi: 10.4161/cbt.28555. Epub 2014 Mar 20. Review.

32.

Plaque-based sub-blistering dosimetry: Reaching PASI-75 after two treatments with 308-nm excimer laser in a generalized psoriasis patient.

Debbaneh MG, Levin E, Sanchez Rodriguez R, Leon A, Koo J, Rosenblum MD.

J Dermatolog Treat. 2015 Feb;26(1):45-8. doi: 10.3109/09546634.2013.879094. Epub 2014 Feb 20.

PMID:
24552548
33.

A case of Wong-type dermatomyositis with concomitant anti-MDA5 features.

Canavan T, Sidorsky T, Doan LT, Ricardo-Gonzalez RR, Shen G, Rosenblum MD.

J Am Acad Dermatol. 2014 Mar;70(3):e62-4. doi: 10.1016/j.jaad.2013.10.035. No abstract available.

34.

Memory regulatory T cells reside in human skin.

Sanchez Rodriguez R, Pauli ML, Neuhaus IM, Yu SS, Arron ST, Harris HW, Yang SH, Anthony BA, Sverdrup FM, Krow-Lucal E, MacKenzie TC, Johnson DS, Meyer EH, Löhr A, Hsu A, Koo J, Liao W, Gupta R, Debbaneh MG, Butler D, Huynh M, Levin EC, Leon A, Hoffman WY, McGrath MH, Alvarado MD, Ludwig CH, Truong HA, Maurano MM, Gratz IK, Abbas AK, Rosenblum MD.

J Clin Invest. 2014 Mar;124(3):1027-36. doi: 10.1172/JCI72932. Epub 2014 Feb 10.

35.

Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues.

Gratz IK, Rosenblum MD, Maurano MM, Paw JS, Truong HA, Marshak-Rothstein A, Abbas AK.

J Immunol. 2014 Feb 15;192(4):1351-5. doi: 10.4049/jimmunol.1301777. Epub 2014 Jan 17.

36.

An open-label study of anakinra for the treatment of moderate to severe hidradenitis suppurativa.

Leslie KS, Tripathi SV, Nguyen TV, Pauli M, Rosenblum MD.

J Am Acad Dermatol. 2014 Feb;70(2):243-51. doi: 10.1016/j.jaad.2013.09.044. Epub 2013 Dec 4.

PMID:
24314876
37.

Cutting edge: ABIN-1 protects against psoriasis by restricting MyD88 signals in dendritic cells.

Callahan JA, Hammer GE, Agelides A, Duong BH, Oshima S, North J, Advincula R, Shifrin N, Truong HA, Paw J, Barrera J, DeFranco A, Rosenblum MD, Malynn BA, Ma A.

J Immunol. 2013 Jul 15;191(2):535-9. doi: 10.4049/jimmunol.1203335. Epub 2013 Jun 19.

38.

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors.

Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, Levy R.

J Clin Invest. 2013 Jun;123(6):2447-63. Erratum in: J Clin Invest. 2013 Nov;123(11):4980.

39.

Cutting Edge: memory regulatory t cells require IL-7 and not IL-2 for their maintenance in peripheral tissues.

Gratz IK, Truong HA, Yang SH, Maurano MM, Lee K, Abbas AK, Rosenblum MD.

J Immunol. 2013 May 1;190(9):4483-7. doi: 10.4049/jimmunol.1300212. Epub 2013 Mar 29.

40.

The life of regulatory T cells.

Gratz IK, Rosenblum MD, Abbas AK.

Ann N Y Acad Sci. 2013 Apr;1283:8-12. doi: 10.1111/nyas.12011. Epub 2013 Feb 12. Review.

PMID:
23402657
41.

Treating human autoimmunity: current practice and future prospects.

Rosenblum MD, Gratz IK, Paw JS, Abbas AK.

Sci Transl Med. 2012 Mar 14;4(125):125sr1. doi: 10.1126/scitranslmed.3003504. Review.

42.

Response to self antigen imprints regulatory memory in tissues.

Rosenblum MD, Gratz IK, Paw JS, Lee K, Marshak-Rothstein A, Abbas AK.

Nature. 2011 Nov 27;480(7378):538-42. doi: 10.1038/nature10664.

43.

Opposing functions of IL-2 and IL-7 in the regulation of immune responses.

Katzman SD, Hoyer KK, Dooms H, Gratz IK, Rosenblum MD, Paw JS, Isakson SH, Abbas AK.

Cytokine. 2011 Oct;56(1):116-21. doi: 10.1016/j.cyto.2011.07.005. Epub 2011 Jul 31. Review.

44.

CD200, a "no danger" signal for hair follicles.

Rosenblum MD, Yancey KB, Olasz EB, Truitt RL.

J Dermatol Sci. 2006 Mar;41(3):165-74. Epub 2006 Jan 4. Review.

PMID:
16386879
45.

Characterization of CD 200-receptor expression in the murine epidermis.

Rosenblum MD, Woodliff JE, Madsen NA, McOlash LJ, Keller MR, Truitt RL.

J Invest Dermatol. 2005 Dec;125(6):1130-8.

46.

Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?

Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL.

J Invest Dermatol. 2004 Nov;123(5):880-7.

47.

Efficacy of alemtuzumab treatment for refractory T-cell large granular lymphocytic leukemia.

Rosenblum MD, LaBelle JL, Chang CC, Margolis DA, Schauer DW, Vesole DH.

Blood. 2004 Mar 1;103(5):1969-71. No abstract available.

48.

CD200 is a novel p53-target gene involved in apoptosis-associated immune tolerance.

Rosenblum MD, Olasz E, Woodliff JE, Johnson BD, Konkol MC, Gerber KA, Orentas RJ, Sandford G, Truitt RL.

Blood. 2004 Apr 1;103(7):2691-8. Epub 2003 Nov 26.

49.
50.

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