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Items: 31

1.

GeNets: a unified web platform for network-based genomic analyses.

Li T, Kim A, Rosenbluh J, Horn H, Greenfeld L, An D, Zimmer A, Liberzon A, Bistline J, Natoli T, Li Y, Tsherniak A, Narayan R, Subramanian A, Liefeld T, Wong B, Thompson D, Calvo S, Carr S, Boehm J, Jaffe J, Mesirov J, Hacohen N, Regev A, Lage K.

Nat Methods. 2018 Jul;15(7):543-546. doi: 10.1038/s41592-018-0039-6. Epub 2018 Jun 18.

2.

Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression.

Rosenbluh J, Xu H, Harrington W, Gill S, Wang X, Vazquez F, Root DE, Tsherniak A, Hahn WC.

Nat Commun. 2017 May 23;8:15403. doi: 10.1038/ncomms15403.

3.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

Rosenbluh J, Mercer J, Shrestha Y, Oliver R, Tamayo P, Doench JG, Tirosh I, Piccioni F, Hartenian E, Horn H, Fagbami L, Root DE, Jaffe J, Lage K, Boehm JS, Hahn WC.

Cell Syst. 2016 Sep 28;3(3):302-316.e4. doi: 10.1016/j.cels.2016.09.001.

4.

Characterizing genomic alterations in cancer by complementary functional associations.

Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, Ghandi M, Greulich H, Vazquez F, Weir BA, Van Allen EM, Tsherniak A, Shao DD, Zack TI, Noble M, Getz G, Beroukhim R, Garraway LA, Ardakani M, Romualdi C, Sales G, Barbie DA, Boehm JS, Hahn WC, Mesirov JP, Tamayo P.

Nat Biotechnol. 2016 May;34(5):539-46. doi: 10.1038/nbt.3527. Epub 2016 Apr 18.

5.

RNF43 is frequently mutated in colorectal and endometrial cancers.

Giannakis M, Hodis E, Jasmine Mu X, Yamauchi M, Rosenbluh J, Cibulskis K, Saksena G, Lawrence MS, Qian ZR, Nishihara R, Van Allen EM, Hahn WC, Gabriel SB, Lander ES, Getz G, Ogino S, Fuchs CS, Garraway LA.

Nat Genet. 2014 Dec;46(12):1264-6. doi: 10.1038/ng.3127. Epub 2014 Oct 26.

6.

KRAS and YAP1 converge to regulate EMT and tumor survival.

Shao DD, Xue W, Krall EB, Bhutkar A, Piccioni F, Wang X, Schinzel AC, Sood S, Rosenbluh J, Kim JW, Zwang Y, Roberts TM, Root DE, Jacks T, Hahn WC.

Cell. 2014 Jul 3;158(1):171-84. doi: 10.1016/j.cell.2014.06.004. Epub 2014 Jun 19.

7.

Genomic insights into WNT/β-catenin signaling.

Rosenbluh J, Wang X, Hahn WC.

Trends Pharmacol Sci. 2014 Feb;35(2):103-9. doi: 10.1016/j.tips.2013.11.007. Epub 2013 Dec 20. Review.

8.

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers.

Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC.

Cancer Discov. 2013 Sep;3(9):1044-57. doi: 10.1158/2159-8290.CD-12-0592. Epub 2013 Jun 13.

9.

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.

Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC.

Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Erratum in: Cell. 2013 Mar 28;153(1):267-70.

10.

Cancer vulnerabilities unveiled by genomic loss.

Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC.

Cell. 2012 Aug 17;150(4):842-54. doi: 10.1016/j.cell.2012.07.023.

11.

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.

Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N, Meeker AK; ALT Starr Cancer Consortium.

PLoS Genet. 2012;8(7):e1002772. Epub 2012 Jul 19.

12.

RMRP is a non-coding RNA essential for early murine development.

Rosenbluh J, Nijhawan D, Chen Z, Wong KK, Masutomi K, Hahn WC.

PLoS One. 2011;6(10):e26270. doi: 10.1371/journal.pone.0026270. Epub 2011 Oct 19.

13.

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM.

Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, Zhuang L, Rosenbluh J, Chen S, Xiao Y, Shapiro GI, Hahn WC, Chin L.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11501-6. doi: 10.1073/pnas.1001613107. Epub 2010 Jun 7.

14.

BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat.

Bugatti A, Chiodelli P, Rosenbluh J, Loyter A, Rusnati M.

Antiviral Res. 2010 Jul;87(1):30-9. doi: 10.1016/j.antiviral.2010.04.004. Epub 2010 Apr 14.

PMID:
20398703
15.

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal.

Levin A, Armon-Omer A, Rosenbluh J, Melamed-Book N, Graessmann A, Waigmann E, Loyter A.

Retrovirology. 2009 Dec 5;6:112. doi: 10.1186/1742-4690-6-112.

16.

Integration of HIV-1 DNA is regulated by interplay between viral rev and cellular LEDGF/p75 proteins.

Levin A, Rosenbluh J, Hayouka Z, Friedler A, Loyter A.

Mol Med. 2010 Jan-Feb;16(1-2):34-44. doi: 10.2119/molmed.2009.00133. Epub 2009 Oct 29.

17.

Regulating TERT: location, location, location.

Rosenbluh J, Nijhawan D, Hahn WC.

Cell Cycle. 2009 Oct 15;8(20):3257. Epub 2009 Oct 15. No abstract available.

PMID:
19823010
18.

Peptides derived from HIV-1 Rev inhibit HIV-1 integrase in a shiftide mechanism.

Hayouka Z, Rosenbluh J, Levin A, Maes M, Loyter A, Friedler A.

Biopolymers. 2008;90(4):481-7. doi: 10.1002/bip.20930.

PMID:
18219678
19.

Inhibiting HIV-1 integrase by shifting its oligomerization equilibrium.

Hayouka Z, Rosenbluh J, Levin A, Loya S, Lebendiker M, Veprintsev D, Kotler M, Hizi A, Loyter A, Friedler A.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8316-21. Epub 2007 May 8.

20.

Interaction between HIV-1 Rev and integrase proteins: a basis for the development of anti-HIV peptides.

Rosenbluh J, Hayouka Z, Loya S, Levin A, Armon-Omer A, Britan E, Hizi A, Kotler M, Friedler A, Loyter A.

J Biol Chem. 2007 May 25;282(21):15743-53. Epub 2007 Apr 2.

21.

Permeabilized mammalian cells as an experimental system for nuclear import of geminiviral karyophilic proteins and of synthetic peptides derived from their nuclear localization signal regions.

Kass G, Arad G, Rosenbluh J, Gafni Y, Graessmann A, Rojas MR, Gilbertson RL, Loyter A.

J Gen Virol. 2006 Sep;87(Pt 9):2709-20.

PMID:
16894212
22.

Positively charged peptides can interact with each other, as revealed by solid phase binding assays.

Rosenbluh J, Kapelnikov A, Shalev DE, Rusnati M, Bugatti A, Loyter A.

Anal Biochem. 2006 May 15;352(2):157-68. Epub 2006 Mar 20.

PMID:
16581010
23.

Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression.

Hariton-Gazal E, Rosenbluh J, Zakai N, Fridkin G, Brack-Werner R, Wolff H, Devaux C, Gilon C, Loyter A.

Biochemistry. 2005 Aug 30;44(34):11555-66.

PMID:
16114892
24.

The plant VirE2 interacting protein 1. a molecular link between the Agrobacterium T-complex and the host cell chromatin?

Loyter A, Rosenbluh J, Zakai N, Li J, Kozlovsky SV, Tzfira T, Citovsky V.

Plant Physiol. 2005 Jul;138(3):1318-21. No abstract available.

25.

Translocation of histone proteins across lipid bilayers and Mycoplasma membranes.

Rosenbluh J, Hariton-Gazal E, Dagan A, Rottem S, Graessmann A, Loyter A.

J Mol Biol. 2005 Jan 14;345(2):387-400.

PMID:
15571730
26.
27.

Direct translocation of histone molecules across cell membranes.

Hariton-Gazal E, Rosenbluh J, Graessmann A, Gilon C, Loyter A.

J Cell Sci. 2003 Nov 15;116(Pt 22):4577-86.

28.

[Ergometry separates sleep apnea syndrome from obesity-hypoventilation after therapy positive pressure ventilation therapy].

Schönhofer B, Rosenblüh J, Voshaar T, Köhler D.

Pneumologie. 1997 Dec;51(12):1115-9. German.

PMID:
9487773
29.

[Increase in hypercapnia in exercise--an unloading strategy?].

Schönhofer B, Geibel M, Wenzel M, Rosenblüh J, Köhler D.

Med Klin (Munich). 1995 Apr;90(1 Suppl 1):17-9. German.

PMID:
7616911
30.

[Effect of a face mask on work of breathing in patients with chronic obstructive respiratory disease].

Schönhofer B, Rosenblüh J, Kemper P, Voshaar T, Köhler D.

Pneumologie. 1995 Mar;49 Suppl 1:209-11. German.

PMID:
7617617
31.

[Evaluation of a portable device for measuring maximal inspiratory pressure (Pimax)].

Schönhofer B, Klauke M, Rosenblüh J, Voshaar T, Köhler D.

Pneumologie. 1993 Dec;47(12):666-9. German.

PMID:
8134324

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