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Items: 1 to 50 of 242

1.

Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.

Smith BD, Kaufman MD, Lu WP, Gupta A, Leary CB, Wise SC, Rutkoski TJ, Ahn YM, Al-Ani G, Bulfer SL, Caldwell TM, Chun L, Ensinger CL, Hood MM, McKinley A, Patt WC, Ruiz-Soto R, Su Y, Telikepalli H, Town A, Turner BA, Vogeti L, Vogeti S, Yates K, Janku F, Abdul Razak AR, Rosen O, Heinrich MC, Flynn DL.

Cancer Cell. 2019 May 13;35(5):738-751.e9. doi: 10.1016/j.ccell.2019.04.006.

PMID:
31085175
2.

A high-throughput inhibition assay to study MERS-CoV antibody interactions using image cytometry.

Rosen O, Chan LL, Abiona OM, Gough P, Wang L, Shi W, Zhang Y, Wang N, Kong WP, McLellan JS, Graham BS, Corbett KS.

J Virol Methods. 2019 Mar;265:77-83. doi: 10.1016/j.jviromet.2018.11.009. Epub 2018 Nov 20.

PMID:
30468747
3.

Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials.

Gupta S, Lau K, Harding CO, Shepherd G, Boyer R, Atkinson JP, Knight V, Olbertz J, Larimore K, Gu Z, Li M, Rosen O, Zoog SJ, Weng HH, Schweighardt B.

EBioMedicine. 2018 Nov;37:366-373. doi: 10.1016/j.ebiom.2018.10.038. Epub 2018 Oct 23.

4.

Induction, titration, and maintenance dosing regimen in a phase 2 study of pegvaliase for control of blood phenylalanine in adults with phenylketonuria.

Zori R, Thomas JA, Shur N, Rizzo WB, Decker C, Rosen O, Li M, Schweighardt B, Larimore K, Longo N.

Mol Genet Metab. 2018 Nov;125(3):217-227. doi: 10.1016/j.ymgme.2018.06.010. Epub 2018 Aug 23.

PMID:
30146451
5.

Studying the differential efficacy of postsymptom antitoxin treatment in type A versus type B botulism using a rabbit spirometry model.

Torgeman A, Schwartz A, Diamant E, Baruchi T, Dor E, Ben David A, Pass A, Barnea A, Tal A, Rosner A, Rosen O, Zichel R.

Dis Model Mech. 2018 Sep 27;11(9). pii: dmm035089. doi: 10.1242/dmm.035089.

6.

Meningomyelocele Simulation Model: Pre-surgical Management-Technical Report.

Rosen O, Angert RM.

Cureus. 2018 Feb 26;10(2):e2231. doi: 10.7759/cureus.2231.

7.

A Novel Rabbit Spirometry Model of Type E Botulism and Its Use for the Evaluation of Postsymptom Antitoxin Efficacy.

Diamant E, Pass A, Rosen O, Ben David A, Torgeman A, Barnea A, Tal A, Rosner A, Zichel R.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e02379-17. doi: 10.1128/AAC.02379-17. Print 2018 Apr.

8.

Conditional Spectral Analysis of Replicated Multiple Time Series with Application to Nocturnal Physiology.

Krafty RT, Rosen O, Stoffer DS, Buysse DJ, Hall MH.

J Am Stat Assoc. 2017;112(520):1405-1416. doi: 10.1080/01621459.2017.1281811. Epub 2017 Jan 20.

9.

The gene encoding the insulin-like androgenic gland hormone in an all-female parthenogenetic crayfish.

Levy T, Rosen O, Simons O, Savaya Alkalay A, Sagi A.

PLoS One. 2017 Dec 20;12(12):e0189982. doi: 10.1371/journal.pone.0189982. eCollection 2017.

10.

Development of a multiplex Endopep-MS assay for simultaneous detection of botulinum toxins A, B and E.

Rosen O, Feldberg L, Yamin TS, Dor E, Barnea A, Weissberg A, Zichel R.

Sci Rep. 2017 Nov 1;7(1):14859. doi: 10.1038/s41598-017-14911-x.

11.

Improving admission medication reconciliation with pharmacists or pharmacy technicians in the emergency department: a randomised controlled trial.

Pevnick JM, Nguyen C, Jackevicius CA, Palmer KA, Shane R, Cook-Wiens G, Rogatko A, Bear M, Rosen O, Seki D, Doyle B, Desai A, Bell DS.

BMJ Qual Saf. 2018 Jul;27(7):512-520. doi: 10.1136/bmjqs-2017-006761. Epub 2017 Oct 6.

12.

Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Brain Metastases Working Group.

Lin NU, Prowell T, Tan AR, Kozak M, Rosen O, Amiri-Kordestani L, White J, Sul J, Perkins L, Beal K, Gaynor R, Kim ES.

J Clin Oncol. 2017 Nov 20;35(33):3760-3773. doi: 10.1200/JCO.2017.74.0761. Epub 2017 Oct 2.

PMID:
28968165
13.

Noise Reduction in the Neonatal Intensive Care Unit: A Quality Improvement Initiative.

Ahamed MF, Campbell D, Horan S, Rosen O.

Am J Med Qual. 2018 Mar/Apr;33(2):177-184. doi: 10.1177/1062860617711563. Epub 2017 Jun 6.

PMID:
28587516
14.

Role of Homologous Fc Fragment in the Potency and Efficacy of Anti-Botulinum Antibody Preparations.

Torgeman A, Ozeri E, Ben David A, Diamant E, Rosen O, Schwartz A, Barnea A, Makovitzki A, Mimran A, Zichel R.

Toxins (Basel). 2017 May 29;9(6). pii: E180. doi: 10.3390/toxins9060180.

15.

Medication adherence as a predictor of 30-day hospital readmissions.

Rosen OZ, Fridman R, Rosen BT, Shane R, Pevnick JM.

Patient Prefer Adherence. 2017 Apr 20;11:801-810. doi: 10.2147/PPA.S125672. eCollection 2017.

16.

Optimization of SNAP-25-derived peptide substrate for improved detection of botulinum A in the Endopep-MS assay.

Rosen O, Feldberg L, Dor E, Gura S, Zichel R.

Anal Biochem. 2017 Jul 1;528:34-37. doi: 10.1016/j.ab.2017.04.012. Epub 2017 Apr 24.

PMID:
28450105
17.

Gastroschisis Simulation Model: Pre-surgical Management Technical Report.

Rosen O, Angert RM.

Cureus. 2017 Mar 22;9(3):e1109. doi: 10.7759/cureus.1109.

18.

Phase 1 dose-finding study of rebastinib (DCC-2036) in patients with relapsed chronic myeloid leukemia and acute myeloid leukemia.

Cortes J, Talpaz M, Smith HP, Snyder DS, Khoury J, Bhalla KN, Pinilla-Ibarz J, Larson R, Mitchell D, Wise SC, Rutkoski TJ, Smith BD, Flynn DL, Kantarjian HM, Rosen O, Van Etten RA.

Haematologica. 2017 Mar;102(3):519-528. doi: 10.3324/haematol.2016.152710. Epub 2016 Dec 7.

19.

Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins.

Rosen O, Ozeri E, Barnea A, David AB, Zichel R.

Toxins (Basel). 2016 Sep 24;8(10). pii: E276. doi: 10.3390/toxins8100276.

20.

A Single Injection of Hypertrophied Androgenic Gland Cells Produces All-Female Aquaculture.

Levy T, Rosen O, Eilam B, Azulay D, Aflalo ED, Manor R, Shechter A, Sagi A.

Mar Biotechnol (NY). 2016 Oct;18(5):554-563. Epub 2016 Sep 21.

PMID:
27650072
21.

Long-term follow-up of fertility and pregnancy in autoimmune diseases after autologous haematopoietic stem cell transplantation.

Massenkeil G, Alexander T, Rosen O, Dörken B, Burmester G, Radbruch A, Hiepe F, Arnold R.

Rheumatol Int. 2016 Nov;36(11):1563-1568. Epub 2016 Aug 13.

PMID:
27522225
22.

Oscillations-free PID control of anesthetic drug delivery in neuromuscular blockade.

Medvedev A, Zhusubaliyev ZT, Rosén O, Silva MM.

Comput Methods Programs Biomed. 2019 Apr;171:119-131. doi: 10.1016/j.cmpb.2016.07.025. Epub 2016 Jul 25.

PMID:
27481776
23.

Simulation as a tool for improving acquisition of neonatal resuscitation skills for obstetric residents.

Bruno CJ, Angert R, Rosen O, Lee C, Vega M, Kim M, Yu Y, Bernstein PS, Goffman D.

J Matern Fetal Neonatal Med. 2016;29(16):2625-9. doi: 10.3109/14767058.2015.1095179. Epub 2015 Oct 12.

PMID:
26456348
24.

Early, Real-Time Medical Diagnosis of Botulism by Endopeptidase-Mass Spectrometry.

Rosen O, Feldberg L, Gura S, Brosh-Nissimov T, Guri A, Zimhony O, Shapiro E, Beth-Din A, Stein D, Ozeri E, Barnea A, Turgeman A, Ben David A, Schwartz A, Elhanany E, Diamant E, Yitzhaki S, Zichel R.

Clin Infect Dis. 2015 Dec 15;61(12):e58-61. doi: 10.1093/cid/civ861. Epub 2015 Sep 28.

PMID:
26420800
25.

Bayesian semiparametric copula estimation with application to psychiatric genetics.

Rosen O, Thompson WK.

Biom J. 2015 May;57(3):468-84. doi: 10.1002/bimj.201300130. Epub 2015 Feb 9.

26.

A new peptide substrate for enhanced botulinum neurotoxin type B detection by endopeptidase-liquid chromatography-tandem mass spectrometry/multiple reaction monitoring assay.

Rosen O, Feldberg L, Gura S, Zichel R.

Anal Biochem. 2015 Mar 15;473:7-10. doi: 10.1016/j.ab.2014.09.016. Epub 2014 Sep 30.

PMID:
25277815
27.

The prawn Macrobrachium vollenhovenii in the Senegal River basin: towards sustainable restocking of all-male populations for biological control of schistosomiasis.

Savaya Alkalay A, Rosen O, Sokolow SH, Faye YP, Faye DS, Aflalo ED, Jouanard N, Zilberg D, Huttinger E, Sagi A.

PLoS Negl Trop Dis. 2014 Aug 28;8(8):e3060. doi: 10.1371/journal.pntd.0003060. eCollection 2014 Aug.

28.

Optimizing dosing of oncology drugs.

Minasian L, Rosen O, Auclair D, Rahman A, Pazdur R, Schilsky RL.

Clin Pharmacol Ther. 2014 Nov;96(5):572-9. doi: 10.1038/clpt.2014.153. Epub 2014 Aug 8. Review.

PMID:
25105705
29.

Improved detection of botulinum type E by rational design of a new peptide substrate for endopeptidase-mass spectrometry assay.

Rosen O, Feldberg L, Gura S, Zichel R.

Anal Biochem. 2014 Jul 1;456:50-2. doi: 10.1016/j.ab.2014.03.024. Epub 2014 Apr 8.

PMID:
24721293
30.

A crayfish insulin-like-binding protein: another piece in the androgenic gland insulin-like hormone puzzle is revealed.

Rosen O, Weil S, Manor R, Roth Z, Khalaila I, Sagi A.

J Biol Chem. 2013 Aug 2;288(31):22289-98. doi: 10.1074/jbc.M113.484279. Epub 2013 Jun 17.

31.

The receptor binding domain of botulinum neurotoxin serotype A (BoNT/A) inhibits BoNT/A and BoNT/E intoxications in vivo.

Ben David A, Diamant E, Barnea A, Rosen O, Torgeman A, Zichel R.

Clin Vaccine Immunol. 2013 Aug;20(8):1266-73. doi: 10.1128/CVI.00268-13. Epub 2013 Jun 12.

32.

Analysis of early hypertension and clinical outcome with bevacizumab: results from seven phase III studies.

Hurwitz HI, Douglas PS, Middleton JP, Sledge GW, Johnson DH, Reardon DA, Chen D, Rosen O.

Oncologist. 2013;18(3):273-80. doi: 10.1634/theoncologist.2012-0339. Epub 2013 Mar 13.

33.

NMR mapping of RANTES surfaces interacting with CCR5 using linked extracellular domains.

Schnur E, Kessler N, Zherdev Y, Noah E, Scherf T, Ding FX, Rabinovich S, Arshava B, Kurbatska V, Leonciks A, Tsimanis A, Rosen O, Naider F, Anglister J.

FEBS J. 2013 May;280(9):2068-84. doi: 10.1111/febs.12230. Epub 2013 Apr 2.

34.

An androgenic gland membrane-anchored gene associated with the crustacean insulin-like androgenic gland hormone.

Rosen O, Manor R, Weil S, Aflalo ED, Bakhrat A, Abdu U, Sagi A.

J Exp Biol. 2013 Jun 1;216(Pt 11):2122-8. doi: 10.1242/jeb.080523. Epub 2013 Mar 7.

35.
36.

Stimulation of molt by RNA interference of the molt-inhibiting hormone in the crayfish Cherax quadricarinatus.

Pamuru RR, Rosen O, Manor R, Chung JS, Zmora N, Glazer L, Aflalo ED, Weil S, Tamone SL, Sagi A.

Gen Comp Endocrinol. 2012 Sep 1;178(2):227-36. doi: 10.1016/j.ygcen.2012.05.007. Epub 2012 Jun 1.

PMID:
22664421
37.

Expression of an Androgenic Gland-Specific Insulin-Like Peptide during the Course of Prawn Sexual and Morphotypic Differentiation.

Ventura T, Manor R, Aflalo ED, Weil S, Khalaila I, Rosen O, Sagi A.

ISRN Endocrinol. 2011;2011:476283. doi: 10.5402/2011/476283. Epub 2011 Apr 11.

38.

Timing sexual differentiation: full functional sex reversal achieved through silencing of a single insulin-like gene in the prawn, Macrobrachium rosenbergii.

Ventura T, Manor R, Aflalo ED, Weil S, Rosen O, Sagi A.

Biol Reprod. 2012 Mar 30;86(3):90. doi: 10.1095/biolreprod.111.097261. Print 2012 Mar.

PMID:
22133694
39.

From the discovery of the crustacean androgenic gland to the insulin-like hormone in six decades.

Ventura T, Rosen O, Sagi A.

Gen Comp Endocrinol. 2011 Sep 15;173(3):381-8. doi: 10.1016/j.ygcen.2011.05.018. Epub 2011 Jun 7. Review.

PMID:
21679714
40.

A sexual shift induced by silencing of a single insulin-like gene in crayfish: ovarian upregulation and testicular degeneration.

Rosen O, Manor R, Weil S, Gafni O, Linial A, Aflalo ED, Ventura T, Sagi A.

PLoS One. 2010 Dec 9;5(12):e15281. doi: 10.1371/journal.pone.0015281.

41.

Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy.

Bagri A, Berry L, Gunter B, Singh M, Kasman I, Damico LA, Xiang H, Schmidt M, Fuh G, Hollister B, Rosen O, Plowman GD.

Clin Cancer Res. 2010 Aug 1;16(15):3887-900. doi: 10.1158/1078-0432.CCR-09-3100. Epub 2010 Jun 16.

42.

A Bayesian regression model for multivariate functional data.

Rosen O, Thompson WK.

Comput Stat Data Anal. 2009 Sep 1;53(11):3773-3786. doi: 10.1016/j.csda.2009.03.026. Epub 2009 Apr 8.

43.

HIV-1 peptide vaccine candidates: selecting constrained V3 peptides with highest affinity to antibody 447-52D.

Mester B, Manor R, Mor A, Arshava B, Rosen O, Ding FX, Naider F, Anglister J.

Biochemistry. 2009 Aug 25;48(33):7867-77. doi: 10.1021/bi900146g.

PMID:
19552398
44.

Epitope mapping of antibody-antigen complexes by nuclear magnetic resonance spectroscopy.

Rosen O, Anglister J.

Methods Mol Biol. 2009;524:37-57. doi: 10.1007/978-1-59745-450-6_3.

PMID:
19377935
45.

Mimicking the structure of the V3 epitope bound to HIV-1 neutralizing antibodies.

Mor A, Segal E, Mester B, Arshava B, Rosen O, Ding FX, Russo J, Dafni A, Schvartzman F, Scherf T, Naider F, Anglister J.

Biochemistry. 2009 Apr 21;48(15):3288-303. doi: 10.1021/bi802308n.

46.
47.

Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: pooled analysis of cohorts of older patients from two randomized clinical trials.

Kabbinavar FF, Hurwitz HI, Yi J, Sarkar S, Rosen O.

J Clin Oncol. 2009 Jan 10;27(2):199-205. doi: 10.1200/JCO.2008.17.7931. Epub 2008 Dec 8.

PMID:
19064978
48.

Leuconostoc septicemia in a preterm neonate on vancomycin therapy: case report and literature review.

Janow G, Lambert B, Scheiner M, Rosen O, Goldman DL, Soghier L.

Am J Perinatol. 2009 Jan;26(1):89-91. doi: 10.1055/s-0028-1103025. Epub 2008 Nov 21. Review.

PMID:
19031357
49.

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system.

Alexander T, Thiel A, Rosen O, Massenkeil G, Sattler A, Kohler S, Mei H, Radtke H, Gromnica-Ihle E, Burmester GR, Arnold R, Radbruch A, Hiepe F.

Blood. 2009 Jan 1;113(1):214-23. doi: 10.1182/blood-2008-07-168286. Epub 2008 Sep 29.

50.

Correlated mutations at gp120 positions 322 and 440: implications for gp120 structure.

Rosen O, Samson AO, Anglister J.

Proteins. 2008 May 15;71(3):1066-70. doi: 10.1002/prot.21982.

PMID:
18275085

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