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The sixth international RASopathies symposium: Precision medicine-From promise to practice.

Gripp KW, Schill L, Schoyer L, Stronach B, Bennett AM, Blaser S, Brown A, Burdine R, Burkitt-Wright E, Castel P, Darilek S, Dias A, Dyer T, Ellis M, Erickson G, Gelb BD, Green T, Gross A, Ho A, Holder JL Jr, Inoue SI, Jelin AC, Kennedy A, Klein R, Kontaridis MI, Magoulas P, McConnell DB, McCormick F, Neel BG, Prada CE, Rauen KA, Roberts A, Rodriguez-Viciana P, Rosen N, Rumbaugh G, Sablina A, Solman M, Tartaglia M, Thomas A, Timmer WC, Venkatachalam K, Walsh KS, Wolters PL, Yi JS, Zenker M, Ratner N.

Am J Med Genet A. 2019 Dec 11. doi: 10.1002/ajmg.a.61434. [Epub ahead of print]


Recommendations for the Study of Vulvar Pain in Women, Part 1: Review of Assessment Tools.

Rosen NO, Bergeron S, Pukall CF.

J Sex Med. 2019 Dec 4. pii: S1743-6095(19)31519-X. doi: 10.1016/j.jsxm.2019.10.023. [Epub ahead of print]


The Influence of Migraine on Driving: Current Understanding, Future Directions, and Potential Implications of Findings.

Tepper SJ, Silberstein SD, Rosen NL, Lipton RB, Dennehy EB, Dowsett SA, Doty E.

Headache. 2019 Dec 2. doi: 10.1111/head.13716. [Epub ahead of print]


A Descriptive and Longitudinal Analysis of Pain During Intercourse in Pregnancy.

Rossi MA, Mooney KM, Binik YM, Rosen NO.

J Sex Med. 2019 Dec;16(12):1966-1977. doi: 10.1016/j.jsxm.2019.09.011. Epub 2019 Oct 21.


Sexual well-being and perceived stress in couples transitioning to parenthood: A dyadic analysis.

Tavares IM, Schlagintweit HE, Nobre PJ, Rosen NO.

Int J Clin Health Psychol. 2019 Sep;19(3):198-208. doi: 10.1016/j.ijchp.2019.07.004. Epub 2019 Aug 13.


Response to Anti-EGFR Therapy in Patients with BRAF non-V600-Mutant Metastatic Colorectal Cancer.

Yaeger R, Kotani D, Mondaca S, Parikh AR, Bando H, Van Seventer EE, Taniguchi H, Zhao H, Thant CN, de Stanchina E, Rosen N, Corcoran RB, Yoshino T, Yao Z, Ebi H.

Clin Cancer Res. 2019 Dec 1;25(23):7089-7097. doi: 10.1158/1078-0432.CCR-19-2004. Epub 2019 Sep 12.


Emotion Regulation in Couples Affected by Female Sexual Interest/Arousal Disorder.

Dubé JP, Corsini-Munt S, Muise A, Rosen NO.

Arch Sex Behav. 2019 Nov;48(8):2491-2506. doi: 10.1007/s10508-019-01465-4. Epub 2019 Aug 29.


Adaptation to temperature stress by Vibrio fischeri facilitates this microbe's symbiosis with the Hawaiian bobtail squid (Euprymna scolopes).

Cohen ML, Mashanova EV, Rosen NM, Soto W.

Evolution. 2019 Sep;73(9):1885-1897. doi: 10.1111/evo.13819. Epub 2019 Aug 26.


Testing the intergenerational model of transmission of risk for chronic pain from parents to their children: an empirical investigation of social transmission pathways.

Higgins KS, Chambers CT, Rosen NO, Sherry S, Mohammadi S, Lynch M, Campbell-Yeo M, Clark AJ.

Pain. 2019 Nov;160(11):2544-2553. doi: 10.1097/j.pain.0000000000001658.


The Importance of Interpersonal Context When Conceptualizing Sexual Pain After Female Genital Cutting.

Rosen NO.

Arch Sex Behav. 2019 Aug 1. doi: 10.1007/s10508-019-01523-x. [Epub ahead of print] No abstract available.


Global view of the RAF-MEK-ERK module and its immediate downstream effectors.

Santini CC, Longden J, Schoof EM, Simpson CD, Jeschke GR, Creixell P, Kim J, Wu X, Turk BE, Rosen N, Poulikakos PI, Linding R.

Sci Rep. 2019 Jul 26;9(1):10865. doi: 10.1038/s41598-019-47245-x.


The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression.

Su W, Han HH, Wang Y, Zhang B, Zhou B, Cheng Y, Rumandla A, Gurrapu S, Chakraborty G, Su J, Yang G, Liang X, Wang G, Rosen N, Scher HI, Ouerfelli O, Giancotti FG.

Cancer Cell. 2019 Aug 12;36(2):139-155.e10. doi: 10.1016/j.ccell.2019.06.009. Epub 2019 Jul 18.


Sexual communal motivation in couples coping with low sexual interest/arousal: Associations with sexual well-being and sexual goals.

Hogue JV, Rosen NO, Bockaj A, Impett EA, Muise A.

PLoS One. 2019 Jul 17;14(7):e0219768. doi: 10.1371/journal.pone.0219768. eCollection 2019.


V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer.

Gao Y, Maria A, Na N, da Cruz Paula A, Gorelick AN, Hechtman JF, Carson J, Lefkowitz RA, Weigelt B, Taylor BS, Zhao H, Reis-Filho JS, de Stanchina E, Rosen N, Yao Z, Yaeger R.

Cancer Discov. 2019 Sep;9(9):1182-1191. doi: 10.1158/2159-8290.CD-19-0356. Epub 2019 Jun 21.


Sexual Motivation in Couples Coping with Female Sexual Interest/Arousal Disorder: A Comparison with Control Couples.

Bockaj A, Rosen NO, Muise A.

J Sex Marital Ther. 2019;45(8):796-808. doi: 10.1080/0092623X.2019.1623356. Epub 2019 Jun 18.


Call for Proposals: Special Section of Archives of Sexual Behavior on Innovative Knowledge Translation in Sex Research.

Rosen NO, Brotto LA.

Arch Sex Behav. 2019 Jul;48(5):1263-1264. doi: 10.1007/s10508-019-01469-0. Epub 2019 May 23. No abstract available.


Perceived Partner Responsiveness Moderates the Associations Between Sexual Talk and Sexual and Relationship Well-Being in Individuals in Long-Term Relationships.

Merwin KE, Rosen NO.

J Sex Res. 2019 May 15:1-14. doi: 10.1080/00224499.2019.1610151. [Epub ahead of print]


Are Depressive Symptoms and Attachment Styles Associated with Observed and Perceived Partner Responsiveness in Couples Coping With Genito-Pelvic Pain ?

Bosisio M, Pâquet M, Bois K, Rosen NO, Bergeron S.

J Sex Res. 2019 May 15:1-11. doi: 10.1080/00224499.2019.1610691. [Epub ahead of print]


Trends in Shoulder Arthroplasty in Israel.

Rosen N, Chechik O, Goldstein Y, Dolkart O, Mozes G, Rak O, Dalich A, Geron Y, Maman E.

Isr Med Assoc J. 2019 Apr;21(4):275-278.


Response to Misused and Misleading: 100% Response Rate to Galcanezumab in Patients With Episodic Migraine.

Rosen N, Pearlman E, Ruff D, Day K, Nagy AJ.

Headache. 2019 Apr;59(4):627-628. doi: 10.1111/head.13514. No abstract available.


Efficacy of MEK inhibition in patients with histiocytic neoplasms.

Diamond EL, Durham BH, Ulaner GA, Drill E, Buthorn J, Ki M, Bitner L, Cho H, Young RJ, Francis JH, Rampal R, Lacouture M, Brody LA, Ozkaya N, Dogan A, Rosen N, Iasonos A, Abdel-Wahab O, Hyman DM.

Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.


Treatment of Vulvodynia: Pharmacological and Non-Pharmacological Approaches.

Rosen NO, Dawson SJ, Brooks M, Kellogg-Spadt S.

Drugs. 2019 Apr;79(5):483-493. doi: 10.1007/s40265-019-01085-1. Review.


Author Correction: The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.

Okada T, Sinha S, Esposito I, Schiavon G, López-Lago MA, Su W, Pratilas CA, Abele C, Hernandez JM, Ohara M, Okada M, Viale A, Heguy A, Socci ND, Sapino A, Seshan VE, Long S, Inghirami G, Rosen N, Giancotti FG.

Nat Cell Biol. 2019 Apr;21(4):534. doi: 10.1038/s41556-019-0288-3.


Acquired BRAF Rearrangements Induce Secondary Resistance to EGFR therapy in EGFR-Mutated Lung Cancers.

Vojnic M, Kubota D, Kurzatkowski C, Offin M, Suzawa K, Benayed R, Schoenfeld AJ, Plodkowski AJ, Poirier JT, Rudin CM, Kris MG, Rosen NX, Yu HA, Riely GJ, Arcila ME, Somwar R, Ladanyi M.

J Thorac Oncol. 2019 May;14(5):802-815. doi: 10.1016/j.jtho.2018.12.038. Epub 2019 Mar 1.


RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.

Yao Z, Gao Y, Su W, Yaeger R, Tao J, Na N, Zhang Y, Zhang C, Rymar A, Tao A, Timaul NM, Mcgriskin R, Outmezguine NA, Zhao H, Chang Q, Qeriqi B, Barbacid M, de Stanchina E, Hyman DM, Bollag G, Rosen N.

Nat Med. 2019 Feb;25(2):284-291. doi: 10.1038/s41591-018-0274-5. Epub 2018 Dec 17.


Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway.

Li Z, Razavi P, Li Q, Toy W, Liu B, Ping C, Hsieh W, Sanchez-Vega F, Brown DN, Da Cruz Paula AF, Morris L, Selenica P, Eichenberger E, Shen R, Schultz N, Rosen N, Scaltriti M, Brogi E, Baselga J, Reis-Filho JS, Chandarlapaty S.

Cancer Cell. 2018 Dec 10;34(6):893-905.e8. doi: 10.1016/j.ccell.2018.11.006.


Partners Experience Consequences, Too: A Comparison of the Sexual, Relational, and Psychological Adjustment of Women with Sexual Interest/Arousal Disorder and Their Partners to Control Couples.

Rosen NO, Dubé JP, Corsini-Munt S, Muise A.

J Sex Med. 2019 Jan;16(1):83-95. doi: 10.1016/j.jsxm.2018.10.018. Epub 2018 Dec 1.


When Mom Has Migraine: An Observational Study of the Impact of Parental Migraine on Adolescent Children.

Seng EK, Mauser ED, Marzouk M, Patel ZS, Rosen N, Buse DC.

Headache. 2019 Feb;59(2):224-234. doi: 10.1111/head.13433. Epub 2018 Oct 31.


Sexual Distress Mediates the Associations Between Sexual Contingent Self-Worth and Well-Being in Women With Genitopelvic Pain: A Dyadic Daily Experience Study.

Glowacka M, Bergeron S, Delisle I, Rosen NO.

J Sex Res. 2019 Mar-Apr;56(3):314-326. doi: 10.1080/00224499.2018.1525334. Epub 2018 Oct 9.


Genito-Pelvic Pain Through a Dyadic Lens: Moving Toward an Interpersonal Emotion Regulation Model of Women's Sexual Dysfunction.

Rosen NO, Bergeron S.

J Sex Res. 2019 May-Jun;56(4-5):440-461. doi: 10.1080/00224499.2018.1513987. Epub 2018 Sep 25.


Update on the Comprehensive Approach to Fragility Fractures.

Cohn MR, Gianakos AL, Grueter K, Rosen N, Cong GT, Lane JM.

J Orthop Trauma. 2018 Sep;32(9):480-490. doi: 10.1097/BOT.0000000000001244. Review.


Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer.

Golfmann K, Meder L, Koker M, Volz C, Borchmann S, Tharun L, Dietlein F, Malchers F, Florin A, Büttner R, Rosen N, Rodrik-Outmezguine V, Hallek M, Ullrich RT.

Oncogene. 2018 Oct;37(42):5682-5693. doi: 10.1038/s41388-018-0380-3. Epub 2018 Jul 3.


A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.

Wang J, Yao Z, Jonsson P, Allen AN, Qin ACR, Uddin S, Dunkel IJ, Petriccione M, Manova K, Haque S, Rosenblum MK, Pisapia DJ, Rosen N, Taylor BS, Pratilas CA.

Cancer Discov. 2018 Sep;8(9):1130-1141. doi: 10.1158/2159-8290.CD-17-1263. Epub 2018 Jun 7.


Blunt traumatic scapular fractures are associated with great vessel injuries in children.

Abd El-Shafy I, Rosen LM, Prince JM, Letton RW, Rosen NG.

J Trauma Acute Care Surg. 2018 Nov;85(5):932-935. doi: 10.1097/TA.0000000000001980.


Expression of Pain Behaviors and Perceived Partner Responses in Individuals With Chronic Pain: The Mediating Role of Partner Burden and Relationship Quality.

Mohammadi S, Chambers CT, Rosen NO.

Clin J Pain. 2018 Oct;34(10):927-935. doi: 10.1097/AJP.0000000000000610.


Sexual Cues Mediate the Daily Associations Between Interpersonal Goals, Pain, and Well-being in Couples Coping With Vulvodynia.

Rosen NO, Muise A, Impett EA, Delisle I, Baxter ML, Bergeron S.

Ann Behav Med. 2018 Feb 17;52(3):216-227. doi: 10.1093/abm/kax046.


Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties.

Gao Y, Chang MT, McKay D, Na N, Zhou B, Yaeger R, Torres NM, Muniz K, Drosten M, Barbacid M, Caponigro G, Stuart D, Moebitz H, Solit DB, Abdel-Wahab O, Taylor BS, Yao Z, Rosen N.

Cancer Discov. 2018 May;8(5):648-661. doi: 10.1158/2159-8290.CD-17-1452. Epub 2018 Feb 26.


Communal motivation in couples coping with vulvodynia: Sexual distress mediates associations with pain, depression, and anxiety.

Muise A, Bergeron S, Impett EA, Delisle I, Rosen NO.

J Psychosom Res. 2018 Mar;106:34-40. doi: 10.1016/j.jpsychores.2018.01.006. Epub 2018 Jan 10.


Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.

Yaeger R, Chatila WK, Lipsyc MD, Hechtman JF, Cercek A, Sanchez-Vega F, Jayakumaran G, Middha S, Zehir A, Donoghue MTA, You D, Viale A, Kemeny N, Segal NH, Stadler ZK, Varghese AM, Kundra R, Gao J, Syed A, Hyman DM, Vakiani E, Rosen N, Taylor BS, Ladanyi M, Berger MF, Solit DB, Shia J, Saltz L, Schultz N.

Cancer Cell. 2018 Jan 8;33(1):125-136.e3. doi: 10.1016/j.ccell.2017.12.004.


Daily Anxiety and Depressive Symptoms in Couples Coping With Vulvodynia: Associations With Women's Pain, Women's Sexual Function, and Both Partners' Sexual Distress.

Pâquet M, Rosen NO, Steben M, Mayrand MH, Santerre-Baillargeon M, Bergeron S.

J Pain. 2018 May;19(5):552-561. doi: 10.1016/j.jpain.2017.12.264. Epub 2018 Jan 5.


When Self-Worth Is Tied to One's Sexual and Romantic Relationship: Associations with Well-Being in Couples Coping with Genito-Pelvic Pain.

Glowacka M, Bergeron S, Dubé J, Rosen NO.

Arch Sex Behav. 2018 Aug;47(6):1649-1661. doi: 10.1007/s10508-017-1126-y. Epub 2018 Jan 5.


Does Self-compassion Benefit Couples Coping With Vulvodynia? Associations With Psychological, Sexual, and Relationship Adjustment.

Santerre-Baillargeon M, Rosen NO, Steben M, Pâquet M, Macabena Perez R, Bergeron S.

Clin J Pain. 2018 Jul;34(7):629-637. doi: 10.1097/AJP.0000000000000579.


Accelerating Discovery of Functional Mutant Alleles in Cancer.

Chang MT, Bhattarai TS, Schram AM, Bielski CM, Donoghue MTA, Jonsson P, Chakravarty D, Phillips S, Kandoth C, Penson A, Gorelick A, Shamu T, Patel S, Harris C, Gao J, Sumer SO, Kundra R, Razavi P, Li BT, Reales DN, Socci ND, Jayakumaran G, Zehir A, Benayed R, Arcila ME, Chandarlapaty S, Ladanyi M, Schultz N, Baselga J, Berger MF, Rosen N, Solit DB, Hyman DM, Taylor BS.

Cancer Discov. 2018 Feb;8(2):174-183. doi: 10.1158/2159-8290.CD-17-0321. Epub 2017 Dec 15.


Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.

Janjigian YY, Sanchez-Vega F, Jonsson P, Chatila WK, Hechtman JF, Ku GY, Riches JC, Tuvy Y, Kundra R, Bouvier N, Vakiani E, Gao J, Heins ZJ, Gross BE, Kelsen DP, Zhang L, Strong VE, Schattner M, Gerdes H, Coit DG, Bains M, Stadler ZK, Rusch VW, Jones DR, Molena D, Shia J, Robson ME, Capanu M, Middha S, Zehir A, Hyman DM, Scaltriti M, Ladanyi M, Rosen N, Ilson DH, Berger MF, Tang L, Taylor BS, Solit DB, Schultz N.

Cancer Discov. 2018 Jan;8(1):49-58. doi: 10.1158/2159-8290.CD-17-0787. Epub 2017 Nov 9.


Vulvodynia: a consideration of clinical and methodological research challenges and recommended solutions.

Corsini-Munt S, Rancourt KM, Dubé JP, Rossi MA, Rosen NO.

J Pain Res. 2017 Oct 9;10:2425-2436. doi: 10.2147/JPR.S126259. eCollection 2017. Review.


A Comparison of Approach and Avoidance Sexual Goals in Couples With Vulvodynia and Community Controls.

Dubé JP, Bergeron S, Muise A, Impett EA, Rosen NO.

J Sex Med. 2017 Nov;14(11):1412-1420. doi: 10.1016/j.jsxm.2017.09.002. Epub 2017 Sep 28.


Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.

Yaeger R, Yao Z, Hyman DM, Hechtman JF, Vakiani E, Zhao H, Su W, Wang L, Joelson A, Cercek A, Baselga J, de Stanchina E, Saltz L, Berger MF, Solit DB, Rosen N.

Cancer Res. 2017 Dec 1;77(23):6513-6523. doi: 10.1158/0008-5472.CAN-17-0768. Epub 2017 Sep 26.

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