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Items: 1 to 50 of 535

1.
2.

RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.

Yao Z, Gao Y, Su W, Yaeger R, Tao J, Na N, Zhang Y, Zhang C, Rymar A, Tao A, Timaul NM, Mcgriskin R, Outmezguine NA, Zhao H, Chang Q, Qeriqi B, Barbacid M, de Stanchina E, Hyman DM, Bollag G, Rosen N.

Nat Med. 2019 Feb;25(2):284-291. doi: 10.1038/s41591-018-0274-5. Epub 2018 Dec 17.

PMID:
30559419
3.

Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway.

Li Z, Razavi P, Li Q, Toy W, Liu B, Ping C, Hsieh W, Sanchez-Vega F, Brown DN, Da Cruz Paula AF, Morris L, Selenica P, Eichenberger E, Shen R, Schultz N, Rosen N, Scaltriti M, Brogi E, Baselga J, Reis-Filho JS, Chandarlapaty S.

Cancer Cell. 2018 Dec 10;34(6):893-905.e8. doi: 10.1016/j.ccell.2018.11.006.

PMID:
30537512
4.

Partners Experience Consequences, Too: A Comparison of the Sexual, Relational, and Psychological Adjustment of Women with Sexual Interest/Arousal Disorder and Their Partners to Control Couples.

Rosen NO, Dubé JP, Corsini-Munt S, Muise A.

J Sex Med. 2019 Jan;16(1):83-95. doi: 10.1016/j.jsxm.2018.10.018. Epub 2018 Dec 1.

PMID:
30509505
5.

When Mom Has Migraine: An Observational Study of the Impact of Parental Migraine on Adolescent Children.

Seng EK, Mauser ED, Marzouk M, Patel ZS, Rosen N, Buse DC.

Headache. 2019 Feb;59(2):224-234. doi: 10.1111/head.13433. Epub 2018 Oct 31.

PMID:
30378682
6.
7.

Sexual Distress Mediates the Associations Between Sexual Contingent Self-Worth and Well-Being in Women With Genitopelvic Pain: A Dyadic Daily Experience Study.

Glowacka M, Bergeron S, Delisle I, Rosen NO.

J Sex Res. 2018 Oct 9:1-13. doi: 10.1080/00224499.2018.1525334. [Epub ahead of print]

PMID:
30299977
8.

Genito-Pelvic Pain Through a Dyadic Lens: Moving Toward an Interpersonal Emotion Regulation Model of Women's Sexual Dysfunction.

Rosen NO, Bergeron S.

J Sex Res. 2018 Sep 25:1-22. doi: 10.1080/00224499.2018.1513987. [Epub ahead of print]

PMID:
30252510
9.

Update on the Comprehensive Approach to Fragility Fractures.

Cohn MR, Gianakos AL, Grueter K, Rosen N, Cong GT, Lane JM.

J Orthop Trauma. 2018 Sep;32(9):480-490. doi: 10.1097/BOT.0000000000001244.

PMID:
30036208
10.

Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer.

Golfmann K, Meder L, Koker M, Volz C, Borchmann S, Tharun L, Dietlein F, Malchers F, Florin A, Büttner R, Rosen N, Rodrik-Outmezguine V, Hallek M, Ullrich RT.

Oncogene. 2018 Oct;37(42):5682-5693. doi: 10.1038/s41388-018-0380-3. Epub 2018 Jul 3.

PMID:
29970903
11.

A Secondary Mutation in BRAF Confers Resistance to RAF Inhibition in a BRAFV600E-Mutant Brain Tumor.

Wang J, Yao Z, Jonsson P, Allen AN, Qin ACR, Uddin S, Dunkel IJ, Petriccione M, Manova K, Haque S, Rosenblum MK, Pisapia DJ, Rosen N, Taylor BS, Pratilas CA.

Cancer Discov. 2018 Sep;8(9):1130-1141. doi: 10.1158/2159-8290.CD-17-1263. Epub 2018 Jun 7.

PMID:
29880583
12.

Blunt traumatic scapular fractures are associated with great vessel injuries in children.

Abd El-Shafy I, Rosen LM, Prince JM, Letton RW, Rosen NG.

J Trauma Acute Care Surg. 2018 Nov;85(5):932-935. doi: 10.1097/TA.0000000000001980.

PMID:
29787531
13.

Expression of Pain Behaviors and Perceived Partner Responses in Individuals With Chronic Pain: The Mediating Role of Partner Burden and Relationship Quality.

Mohammadi S, Chambers CT, Rosen NO.

Clin J Pain. 2018 Oct;34(10):927-935. doi: 10.1097/AJP.0000000000000610.

PMID:
29554033
14.

Sexual Cues Mediate the Daily Associations Between Interpersonal Goals, Pain, and Well-being in Couples Coping With Vulvodynia.

Rosen NO, Muise A, Impett EA, Delisle I, Baxter ML, Bergeron S.

Ann Behav Med. 2018 Feb 17;52(3):216-227. doi: 10.1093/abm/kax046.

PMID:
29538663
15.

Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties.

Gao Y, Chang MT, McKay D, Na N, Zhou B, Yaeger R, Torres NM, Muniz K, Drosten M, Barbacid M, Caponigro G, Stuart D, Moebitz H, Solit DB, Abdel-Wahab O, Taylor BS, Yao Z, Rosen N.

Cancer Discov. 2018 May;8(5):648-661. doi: 10.1158/2159-8290.CD-17-1452. Epub 2018 Feb 26.

PMID:
29483135
16.

Communal motivation in couples coping with vulvodynia: Sexual distress mediates associations with pain, depression, and anxiety.

Muise A, Bergeron S, Impett EA, Delisle I, Rosen NO.

J Psychosom Res. 2018 Mar;106:34-40. doi: 10.1016/j.jpsychores.2018.01.006. Epub 2018 Jan 10.

PMID:
29455897
17.

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.

Yaeger R, Chatila WK, Lipsyc MD, Hechtman JF, Cercek A, Sanchez-Vega F, Jayakumaran G, Middha S, Zehir A, Donoghue MTA, You D, Viale A, Kemeny N, Segal NH, Stadler ZK, Varghese AM, Kundra R, Gao J, Syed A, Hyman DM, Vakiani E, Rosen N, Taylor BS, Ladanyi M, Berger MF, Solit DB, Shia J, Saltz L, Schultz N.

Cancer Cell. 2018 Jan 8;33(1):125-136.e3. doi: 10.1016/j.ccell.2017.12.004.

18.

Daily Anxiety and Depressive Symptoms in Couples Coping With Vulvodynia: Associations With Women's Pain, Women's Sexual Function, and Both Partners' Sexual Distress.

Pâquet M, Rosen NO, Steben M, Mayrand MH, Santerre-Baillargeon M, Bergeron S.

J Pain. 2018 May;19(5):552-561. doi: 10.1016/j.jpain.2017.12.264. Epub 2018 Jan 5.

PMID:
29309891
19.

When Self-Worth Is Tied to One's Sexual and Romantic Relationship: Associations with Well-Being in Couples Coping with Genito-Pelvic Pain.

Glowacka M, Bergeron S, Dubé J, Rosen NO.

Arch Sex Behav. 2018 Aug;47(6):1649-1661. doi: 10.1007/s10508-017-1126-y. Epub 2018 Jan 5.

PMID:
29305775
20.

Does Self-compassion Benefit Couples Coping With Vulvodynia? Associations With Psychological, Sexual, and Relationship Adjustment.

Santerre-Baillargeon M, Rosen NO, Steben M, Pâquet M, Macabena Perez R, Bergeron S.

Clin J Pain. 2018 Jul;34(7):629-637. doi: 10.1097/AJP.0000000000000579.

PMID:
29271798
21.

Accelerating Discovery of Functional Mutant Alleles in Cancer.

Chang MT, Bhattarai TS, Schram AM, Bielski CM, Donoghue MTA, Jonsson P, Chakravarty D, Phillips S, Kandoth C, Penson A, Gorelick A, Shamu T, Patel S, Harris C, Gao J, Sumer SO, Kundra R, Razavi P, Li BT, Reales DN, Socci ND, Jayakumaran G, Zehir A, Benayed R, Arcila ME, Chandarlapaty S, Ladanyi M, Schultz N, Baselga J, Berger MF, Rosen N, Solit DB, Hyman DM, Taylor BS.

Cancer Discov. 2018 Feb;8(2):174-183. doi: 10.1158/2159-8290.CD-17-0321. Epub 2017 Dec 15.

22.

Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer.

Janjigian YY, Sanchez-Vega F, Jonsson P, Chatila WK, Hechtman JF, Ku GY, Riches JC, Tuvy Y, Kundra R, Bouvier N, Vakiani E, Gao J, Heins ZJ, Gross BE, Kelsen DP, Zhang L, Strong VE, Schattner M, Gerdes H, Coit DG, Bains M, Stadler ZK, Rusch VW, Jones DR, Molena D, Shia J, Robson ME, Capanu M, Middha S, Zehir A, Hyman DM, Scaltriti M, Ladanyi M, Rosen N, Ilson DH, Berger MF, Tang L, Taylor BS, Solit DB, Schultz N.

Cancer Discov. 2018 Jan;8(1):49-58. doi: 10.1158/2159-8290.CD-17-0787. Epub 2017 Nov 9.

23.

Vulvodynia: a consideration of clinical and methodological research challenges and recommended solutions.

Corsini-Munt S, Rancourt KM, Dubé JP, Rossi MA, Rosen NO.

J Pain Res. 2017 Oct 9;10:2425-2436. doi: 10.2147/JPR.S126259. eCollection 2017. Review.

24.

A Comparison of Approach and Avoidance Sexual Goals in Couples With Vulvodynia and Community Controls.

Dubé JP, Bergeron S, Muise A, Impett EA, Rosen NO.

J Sex Med. 2017 Nov;14(11):1412-1420. doi: 10.1016/j.jsxm.2017.09.002. Epub 2017 Sep 28.

PMID:
28964711
25.

Mechanisms of Acquired Resistance to BRAF V600E Inhibition in Colon Cancers Converge on RAF Dimerization and Are Sensitive to Its Inhibition.

Yaeger R, Yao Z, Hyman DM, Hechtman JF, Vakiani E, Zhao H, Su W, Wang L, Joelson A, Cercek A, Baselga J, de Stanchina E, Saltz L, Berger MF, Solit DB, Rosen N.

Cancer Res. 2017 Dec 1;77(23):6513-6523. doi: 10.1158/0008-5472.CAN-17-0768. Epub 2017 Sep 26.

26.

Headache Interest in Academic Neurology Leadership: A Cross-Sectional Study.

Robbins MS, Rosen NL.

Headache. 2018 Jan;58(1):102-108. doi: 10.1111/head.13186. Epub 2017 Sep 21.

PMID:
28940337
27.

A Braf kinase-inactive mutant induces lung adenocarcinoma.

Nieto P, Ambrogio C, Esteban-Burgos L, Gómez-López G, Blasco MT, Yao Z, Marais R, Rosen N, Chiarle R, Pisano DG, Barbacid M, Santamaría D.

Nature. 2017 Aug 10;548(7666):239-243. doi: 10.1038/nature23297. Epub 2017 Aug 2.

28.

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Yao Z, Yaeger R, Rodrik-Outmezguine VS, Tao A, Torres NM, Chang MT, Drosten M, Zhao H, Cecchi F, Hembrough T, Michels J, Baumert H, Miles L, Campbell NM, de Stanchina E, Solit DB, Barbacid M, Taylor BS, Rosen N.

Nature. 2017 Aug 10;548(7666):234-238. doi: 10.1038/nature23291. Epub 2017 Aug 2.

29.

An approach to suppress the evolution of resistance in BRAFV600E-mutant cancer.

Xue Y, Martelotto L, Baslan T, Vides A, Solomon M, Mai TT, Chaudhary N, Riely GJ, Li BT, Scott K, Cechhi F, Stierner U, Chadalavada K, de Stanchina E, Schwartz S, Hembrough T, Nanjangud G, Berger MF, Nilsson J, Lowe SW, Reis-Filho JS, Rosen N, Lito P.

Nat Med. 2017 Aug;23(8):929-937. doi: 10.1038/nm.4369. Epub 2017 Jul 17.

30.

Prevalence and Predictors of Chronic Pain in Pregnancy and Postpartum.

Munro A, George RB, Chorney J, Snelgrove-Clarke E, Rosen NO.

J Obstet Gynaecol Can. 2017 Sep;39(9):734-741. doi: 10.1016/j.jogc.2017.01.026. Epub 2017 Jun 16.

PMID:
28624445
31.

Injectable DaxibotulinumtoxinA for the Treatment of Glabellar Lines: A Phase 2, Randomized, Dose-Ranging, Double-Blind, Multicenter Comparison With OnabotulinumtoxinA and Placebo.

Carruthers J, Solish N, Humphrey S, Rosen N, Muhn C, Bertucci V, Swift A, Metelitsa A, Rubio RG, Waugh J, Quiring J, Shears G, Carruthers A.

Dermatol Surg. 2017 Nov;43(11):1321-1331. doi: 10.1097/DSS.0000000000001206.

PMID:
28614091
32.

GeneHancer: genome-wide integration of enhancers and target genes in GeneCards.

Fishilevich S, Nudel R, Rappaport N, Hadar R, Plaschkes I, Iny Stein T, Rosen N, Kohn A, Twik M, Safran M, Lancet D, Cohen D.

Database (Oxford). 2017 Jan 1;2017. doi: 10.1093/database/bax028.

33.

Degree and Direction of Sexual Desire Discrepancy are Linked to Sexual and Relationship Satisfaction in Couples Transitioning to Parenthood.

Rosen NO, Bailey K, Muise A.

J Sex Res. 2018 Feb;55(2):214-225. doi: 10.1080/00224499.2017.1321732. Epub 2017 May 19.

PMID:
28524698
34.

Very long term success of pterygium surgery with conjunctival graft.

Zloto O, Rosen N, Leshno A, Rosner M.

Cont Lens Anterior Eye. 2017 Aug;40(4):267-269. doi: 10.1016/j.clae.2017.05.004. Epub 2017 May 15.

PMID:
28522251
35.

Fear-based reasons for not engaging in sexual activity during pregnancy: associations with sexual and relationship well-being.

Beveridge JK, Vannier SA, Rosen NO.

J Psychosom Obstet Gynaecol. 2018 Jun;39(2):138-145. doi: 10.1080/0167482X.2017.1312334. Epub 2017 Apr 12.

PMID:
28401772
36.

Understanding When a Partner Is Not in the Mood: Sexual Communal Strength in Couples Transitioning to Parenthood.

Muise A, Kim JJ, Impett EA, Rosen NO.

Arch Sex Behav. 2017 Oct;46(7):1993-2006. doi: 10.1007/s10508-016-0920-2. Epub 2017 Mar 21.

PMID:
28324220
37.

Rotator interval closure has no additional effect on shoulder stability compared to Bankart repair alone.

Maman E, Dolkart O, Kazum E, Rosen N, Mozes G, Drexler M, Chechik O.

Arch Orthop Trauma Surg. 2017 May;137(5):673-677. doi: 10.1007/s00402-017-2665-3. Epub 2017 Mar 7.

PMID:
28271283
38.

Evaluation of Online and In-Person Nutrition Education Related to Salt Knowledge and Behaviors among Special Supplemental Nutrition Program for Women, Infants, and Children Participants.

Au LE, Whaley SE, Gurzo K, Meza M, Rosen NJ, Ritchie LD.

J Acad Nutr Diet. 2017 Sep;117(9):1384-1395. doi: 10.1016/j.jand.2016.12.013. Epub 2017 Feb 9.

PMID:
28196620
39.

It Takes Two: Sexual Communication Patterns and the Sexual and Relational Adjustment of Couples Coping With Provoked Vestibulodynia.

Rancourt KM, Flynn M, Bergeron S, Rosen NO.

J Sex Med. 2017 Mar;14(3):434-443. doi: 10.1016/j.jsxm.2017.01.009. Epub 2017 Feb 8.

PMID:
28189562
40.

The costs and benefits of sexual communal motivation for couples coping with vulvodynia.

Muise A, Bergeron S, Impett EA, Rosen NO.

Health Psychol. 2017 Aug;36(8):819-827. doi: 10.1037/hea0000470. Epub 2017 Feb 6.

PMID:
28165264
41.

Phenformin Enhances the Efficacy of ERK Inhibition in NF1-Mutant Melanoma.

Trousil S, Chen S, Mu C, Shaw FM, Yao Z, Ran Y, Shakuntala T, Merghoub T, Manstein D, Rosen N, Cantley LC, Zippin JH, Zheng B.

J Invest Dermatol. 2017 May;137(5):1135-1143. doi: 10.1016/j.jid.2017.01.013. Epub 2017 Jan 28.

42.

Sexual Distress and Sexual Problems During Pregnancy: Associations With Sexual and Relationship Satisfaction.

Vannier SA, Rosen NO.

J Sex Med. 2017 Mar;14(3):387-395. doi: 10.1016/j.jsxm.2016.12.239. Epub 2017 Jan 28.

PMID:
28143716
43.

We Need to Talk: Disclosure of Sexual Problems Is Associated With Depression, Sexual Functioning, and Relationship Satisfaction in Women.

Merwin KE, O'Sullivan LF, Rosen NO.

J Sex Marital Ther. 2017 Nov 17;43(8):786-800. doi: 10.1080/0092623X.2017.1283378. Epub 2017 Jan 20.

PMID:
28107110
44.

A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.

Sun Y, Alberta JA, Pilarz C, Calligaris D, Chadwick EJ, Ramkissoon SH, Ramkissoon LA, Garcia VM, Mazzola E, Goumnerova L, Kane M, Yao Z, Kieran MW, Ligon KL, Hahn WC, Garraway LA, Rosen N, Gray NS, Agar NY, Buhrlage SJ, Segal RA, Stiles CD.

Neuro Oncol. 2017 Jun 1;19(6):774-785. doi: 10.1093/neuonc/now261.

45.

Interpersonal Goals and Well-Being in Couples Coping with Genito-Pelvic Pain.

Rosen NO, Dewitte M, Merwin K, Bergeron S.

Arch Sex Behav. 2017 Oct;46(7):2007-2019. doi: 10.1007/s10508-016-0877-1. Epub 2016 Dec 27.

PMID:
28028667
46.

Comparing the Prevalence, Risk Factors, and Repercussions of Postpartum Genito-Pelvic Pain and Dyspareunia.

Rosen NO, Pukall C.

Sex Med Rev. 2016 Apr;4(2):126-135. doi: 10.1016/j.sxmr.2015.12.003. Epub 2016 Jan 11. Review.

PMID:
27872022
47.

Impact of Extent of Resection on Local Control and Survival in Patients From the COG A3973 Study With High-Risk Neuroblastoma.

von Allmen D, Davidoff AM, London WB, Van Ryn C, Haas-Kogan DA, Kreissman SG, Khanna G, Rosen N, Park JR, La Quaglia MP.

J Clin Oncol. 2017 Jan 10;35(2):208-216. Epub 2016 Nov 21.

48.

How implicit theories of sexuality shape sexual and relationship well-being.

Maxwell JA, Muise A, MacDonald G, Day LC, Rosen NO, Impett EA.

J Pers Soc Psychol. 2017 Feb;112(2):238-279. doi: 10.1037/pspi0000078. Epub 2016 Nov 3.

PMID:
27808534
49.

Kinase Regulation of Human MHC Class I Molecule Expression on Cancer Cells.

Brea EJ, Oh CY, Manchado E, Budhu S, Gejman RS, Mo G, Mondello P, Han JE, Jarvis CA, Ulmert D, Xiang Q, Chang AY, Garippa RJ, Merghoub T, Wolchok JD, Rosen N, Lowe SW, Scheinberg DA.

Cancer Immunol Res. 2016 Nov;4(11):936-947. Epub 2016 Sep 28.

50.

Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine.

Nagarajah J, Le M, Knauf JA, Ferrandino G, Montero-Conde C, Pillarsetty N, Bolaender A, Irwin C, Krishnamoorthy GP, Saqcena M, Larson SM, Ho AL, Seshan V, Ishii N, Carrasco N, Rosen N, Weber WA, Fagin JA.

J Clin Invest. 2016 Nov 1;126(11):4119-4124. doi: 10.1172/JCI89067. Epub 2016 Sep 26.

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