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Items: 1 to 50 of 377

1.

Correction: Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression.

Kim SJ, Garcia-Recio S, Creighton CJ, Perou CM, Rosen JM.

Oncogene. 2019 Sep 26. doi: 10.1038/s41388-019-1017-x. [Epub ahead of print]

PMID:
31558798
2.

Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms.

Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH.

Nat Cell Biol. 2019 Sep;21(9):1113-1126. doi: 10.1038/s41556-019-0373-7. Epub 2019 Aug 26.

PMID:
31451770
3.

Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression.

Kim SJ, Garcia-Recio S, Creighton CJ, Perou CM, Rosen JM.

Oncogene. 2019 Aug;38(31):5942-5958. doi: 10.1038/s41388-019-0852-0. Epub 2019 Jul 9. Erratum in: Oncogene. 2019 Sep 26;:.

PMID:
31289359
4.

The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor.

Pfefferle AD, Darr DB, Calhoun BC, Mott KR, Rosen JM, Perou CM.

Dis Model Mech. 2019 Jul 5;12(7). pii: dmm037192. doi: 10.1242/dmm.037192.

5.

Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy.

Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA.

Cancers (Basel). 2019 May 24;11(5). pii: E714. doi: 10.3390/cancers11050714. Review.

6.

Metastasis Organotropism: Redefining the Congenial Soil.

Gao Y, Bado I, Wang H, Zhang W, Rosen JM, Zhang XH.

Dev Cell. 2019 May 6;49(3):375-391. doi: 10.1016/j.devcel.2019.04.012. Review.

PMID:
31063756
7.

GSK3β regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer.

Vijay GV, Zhao N, Den Hollander P, Toneff MJ, Joseph R, Pietila M, Taube JH, Sarkar TR, Ramirez-Pena E, Werden SJ, Shariati M, Gao R, Sobieski M, Stephan CC, Sphyris N, Miura N, Davies P, Chang JT, Soundararajan R, Rosen JM, Mani SA.

Breast Cancer Res. 2019 Mar 7;21(1):37. doi: 10.1186/s13058-019-1125-0.

8.

miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution.

Lu Y, Cao J, Napoli M, Xia Z, Zhao N, Creighton CJ, Li W, Chen X, Flores ER, McManus MT, Rosen JM.

Stem Cells. 2018 Dec;36(12):1875-1889. doi: 10.1002/stem.2914. Epub 2018 Oct 31.

9.

Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target?

Janghorban M, Xin L, Rosen JM, Zhang XH.

Front Immunol. 2018 Jul 16;9:1649. doi: 10.3389/fimmu.2018.01649. eCollection 2018. Review.

10.

Freeze-cast Porous Chitosan Conduit for Peripheral Nerve Repair.

Yin K, Divakar P, Hong J, Moodie KL, Rosen JM, Sundback CA, Matthew MK, Wegst UGK.

MRS Adv. 2018;3(30):1677-1683. doi: 10.1557/adv.2018.194. Epub 2018 Feb 20.

11.

The role of undifferentiated adipose-derived stem cells in peripheral nerve repair.

Zhang R, Rosen JM.

Neural Regen Res. 2018 May;13(5):757-763. doi: 10.4103/1673-5374.232457.

12.

FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.

Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM.

Cancer Res. 2018 Aug 1;78(15):4229-4240. doi: 10.1158/0008-5472.CAN-18-0631. Epub 2018 May 29.

13.

TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain.

Rosen JM, Yaggie RE, Woida PJ, Miller RJ, Schaeffer AJ, Klumpp DJ.

Sci Rep. 2018 May 8;8(1):7188. doi: 10.1038/s41598-018-24056-0.

14.

Overlap between functional abdominal pain disorders and organic diseases in children.

Langshaw AH, Rosen JM, Pensabene L, Borrelli O, Salvatore S, Thapar N, Concolino D, Saps M.

Rev Gastroenterol Mex. 2018 Jul - Sep;83(3):268-274. doi: 10.1016/j.rgmx.2018.02.002. Epub 2018 Apr 3. Review. English, Spanish.

15.

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.

Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X.

J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26.

16.

A nationwide study on the prevalence of functional gastrointestinal disorders in school-children.

Saps M, Moreno-Gomez JE, Ramírez-Hernández CR, Rosen JM, Velasco-Benitez CA.

Bol Med Hosp Infant Mex. 2017 Nov - Dec;74(6):407-412. doi: 10.1016/j.bmhimx.2017.05.005. Epub 2017 Sep 1.

17.

Genome-wide identification and differential analysis of translational initiation.

Zhang P, He D, Xu Y, Hou J, Pan BF, Wang Y, Liu T, Davis CM, Ehli EA, Tan L, Zhou F, Hu J, Yu Y, Chen X, Nguyen TM, Rosen JM, Hawke DH, Ji Z, Chen Y.

Nat Commun. 2017 Nov 23;8(1):1749. doi: 10.1038/s41467-017-01981-8.

18.

Acyloxyacyl hydrolase modulates pelvic pain severity.

Yang W, Yaggie RE, Jiang MC, Rudick CN, Done J, Heckman CJ, Rosen JM, Schaeffer AJ, Klumpp DJ.

Am J Physiol Regul Integr Comp Physiol. 2018 Mar 1;314(3):R353-R365. doi: 10.1152/ajpregu.00239.2017. Epub 2017 Nov 8.

19.

WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis.

Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM.

Dev Cell. 2017 Nov 20;43(4):436-448.e6. doi: 10.1016/j.devcel.2017.10.007. Epub 2017 Nov 2.

20.

Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression.

Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM.

Oncogene. 2017 Oct 26;36(43):5958-5968. doi: 10.1038/onc.2017.206. Epub 2017 Jun 26.

21.

Utility of Gastric and Duodenal Biopsies During Follow-up Endoscopy in Children With Eosinophilic Esophagitis.

Kaur S, Rosen JM, Kriegermeier AA, Wechsler JB, Kagalwalla AF, Brown JB.

J Pediatr Gastroenterol Nutr. 2017 Oct;65(4):399-403. doi: 10.1097/MPG.0000000000001528.

22.

Repurposing Antiestrogens for Tumor Immunotherapy.

Welte T, Zhang XH, Rosen JM.

Cancer Discov. 2017 Jan;7(1):17-19. doi: 10.1158/2159-8290.CD-16-1308.

23.

The Cellular Origin and Evolution of Breast Cancer.

Zhang M, Lee AV, Rosen JM.

Cold Spring Harb Perspect Med. 2017 Mar 1;7(3). pii: a027128. doi: 10.1101/cshperspect.a027128. Review.

24.

TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway.

Su X, Napoli M, Abbas HA, Venkatanarayan A, Bui NHB, Coarfa C, Gi YJ, Kittrell F, Gunaratne PH, Medina D, Rosen JM, Behbod F, Flores ER.

Oncogene. 2017 Apr 27;36(17):2377-2393. doi: 10.1038/onc.2016.388. Epub 2016 Nov 21.

25.

Fatal attraction: TICs and MDSCs.

Welte T, Rosen JM, Zhang XH.

Cell Cycle. 2016 Oct;15(19):2545-2546. Epub 2016 Aug 30. No abstract available.

26.

Prevalence of overlap syndromes and symptoms in pediatric functional dyspepsia.

Friesen CA, Rosen JM, Schurman JV.

BMC Gastroenterol. 2016 Jul 25;16(1):75. doi: 10.1186/s12876-016-0495-3.

27.

Advances in Pain-Predominant Functional Gastrointestinal Disorders in the Adolescent.

Rosen JM, Alioto A, Saps M.

Adolesc Med State Art Rev. 2016 Spring;27(1):34-56. Review. No abstract available.

PMID:
27363232
28.

Cybercare 2.0: meeting the challenge of the global burden of disease in 2030.

Rosen JM, Kun L, Mosher RE, Grigg E, Merrell RC, Macedonia C, Klaudt-Moreau J, Price-Smith A, Geiling J.

Health Technol (Berl). 2016;6:35-51. Epub 2016 May 27.

29.

Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH.

Nat Cell Biol. 2016 Jun 28;18(7):822. doi: 10.1038/ncb3379. No abstract available.

PMID:
27350446
30.

The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states.

Toneff MJ, Sreekumar A, Tinnirello A, Hollander PD, Habib S, Li S, Ellis MJ, Xin L, Mani SA, Rosen JM.

BMC Biol. 2016 Jun 17;14:47. doi: 10.1186/s12915-016-0269-y.

31.

Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth.

Werden SJ, Sphyris N, Sarkar TR, Paranjape AN, LaBaff AM, Taube JH, Hollier BG, Ramirez-Peña EQ, Soundararajan R, den Hollander P, Powell E, Echeverria GV, Miura N, Chang JT, Piwnica-Worms H, Rosen JM, Mani SA.

Oncogene. 2016 Nov 17;35(46):5977-5988. doi: 10.1038/onc.2016.203. Epub 2016 Jun 13.

32.

Perceptions of the Feasibility and Practicalities of Text Messaging-Based Infectious Disease Surveillance: A Questionnaire Survey.

Dang LT, Vu NC, Vu TD, James SL, Katona P, Katona L, Rosen JM, Nguyen CK.

JMIR Mhealth Uhealth. 2016 May 25;4(2):e65. doi: 10.2196/mhealth.4509.

33.

Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation.

Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH.

Nat Cell Biol. 2016 Jun;18(6):632-44. doi: 10.1038/ncb3355. Epub 2016 May 16. Erratum in: Nat Cell Biol. 2016 Jun 28;18(7):822.

34.

Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.

Pfefferle AD, Agrawal YN, Koboldt DC, Kanchi KL, Herschkowitz JI, Mardis ER, Rosen JM, Perou CM.

Dis Model Mech. 2016 Jul 1;9(7):749-57. doi: 10.1242/dmm.025239. Epub 2016 May 5.

35.
36.

Developmental Insights into Breast Cancer Intratumoral Heterogeneity.

Zhang M, Rosen JM.

Trends Cancer. 2015 Dec 1;1(4):242-251.

37.

Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer.

Holdman XB, Welte T, Rajapakshe K, Pond A, Coarfa C, Mo Q, Huang S, Hilsenbeck SG, Edwards DP, Zhang X, Rosen JM.

Breast Cancer Res. 2015 Nov 18;17:141. doi: 10.1186/s13058-015-0649-1.

38.

PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland.

Shore AN, Chang CH, Kwon OJ, Weston MC, Zhang M, Xin L, Rosen JM.

Dev Biol. 2016 Jan 1;409(1):202-217. doi: 10.1016/j.ydbio.2015.10.023. Epub 2015 Oct 23.

39.

Constipation and Encopresis in Childhood.

Colombo JM, Wassom MC, Rosen JM.

Pediatr Rev. 2015 Sep;36(9):392-401; quiz 402. doi: 10.1542/pir.36-9-392. Review. No abstract available.

PMID:
26330473
40.

Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage.

Chang CH, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, Rosen JM.

Stem Cell Reports. 2015 Sep 8;5(3):378-91. doi: 10.1016/j.stemcr.2015.07.009. Epub 2015 Aug 20.

41.

The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes.

Sreekumar A, Roarty K, Rosen JM.

Endocr Relat Cancer. 2015 Dec;22(6):T161-76. doi: 10.1530/ERC-15-0263. Epub 2015 Jul 23. Review.

42.

Nitric Oxide-Releasing Nanoparticles Prevent Propionibacterium acnes-Induced Inflammation by Both Clearing the Organism and Inhibiting Microbial Stimulation of the Innate Immune Response.

Qin M, Landriscina A, Rosen JM, Wei G, Kao S, Olcott W, Agak GW, Paz KB, Bonventre J, Clendaniel A, Harper S, Adler BL, Krausz AE, Friedman JM, Nosanchuk JD, Kim J, Friedman AJ.

J Invest Dermatol. 2015 Nov;135(11):2723-2731. doi: 10.1038/jid.2015.277. Epub 2015 Jul 14.

43.

Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer.

Silva GO, He X, Parker JS, Gatza ML, Carey LA, Hou JP, Moulder SL, Marcom PK, Ma J, Rosen JM, Perou CM.

Breast Cancer Res Treat. 2015 Jul;152(2):347-56. doi: 10.1007/s10549-015-3476-2. Epub 2015 Jun 25.

44.

The cost effectiveness of the DIEP flap relative to the muscle-sparing TRAM flap in postmastectomy breast reconstruction.

Krishnan NM, Purnell C, Nahabedian MY, Freed GL, Nigriny JF, Rosen JM, Rosson GD.

Plast Reconstr Surg. 2015 Apr;135(4):948-58. doi: 10.1097/PRS.0000000000001125. Review.

PMID:
25811560
45.

Biafine topical emulsion accelerates excisional and burn wound healing in mice.

Krausz AE, Adler BL, Landriscina A, Rosen JM, Musaev T, Nosanchuk JD, Friedman AJ.

Arch Dermatol Res. 2015 Sep;307(7):583-94. doi: 10.1007/s00403-015-1559-x. Epub 2015 Mar 21.

PMID:
25794496
46.

Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential.

Knezevic J, Pfefferle AD, Petrovic I, Greene SB, Perou CM, Rosen JM.

Oncogene. 2015 Dec 3;34(49):5997-6006. doi: 10.1038/onc.2015.48. Epub 2015 Mar 9.

47.

Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer.

Zhang M, Tsimelzon A, Chang CH, Fan C, Wolff A, Perou CM, Hilsenbeck SG, Rosen JM.

Cancer Discov. 2015 May;5(5):520-33. doi: 10.1158/2159-8290.CD-14-1101. Epub 2015 Mar 3.

48.

Urinary tract infection in infancy is a risk factor for chronic abdominal pain in childhood.

Rosen JM, Kriegermeier A, Adams PN, Klumpp DJ, Saps M.

J Pediatr Gastroenterol Nutr. 2015 Feb;60(2):214-6. doi: 10.1097/MPG.0000000000000599.

PMID:
25625577
49.

Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.

Roarty K, Shore AN, Creighton CJ, Rosen JM.

J Cell Biol. 2015 Feb 2;208(3):351-66. doi: 10.1083/jcb.201408058. Epub 2015 Jan 26.

50.

The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells.

Wang H, Yu C, Gao X, Welte T, Muscarella AM, Tian L, Zhao H, Zhao Z, Du S, Tao J, Lee B, Westbrook TF, Wong ST, Jin X, Rosen JM, Osborne CK, Zhang XH.

Cancer Cell. 2015 Feb 9;27(2):193-210. doi: 10.1016/j.ccell.2014.11.017. Epub 2015 Jan 15.

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