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Items: 1 to 50 of 322

1.

Glutamine independence is a selectable feature of pluripotent stem cells.

Vardhana SA, Arnold PK, Rosen BP, Chen Y, Carey BW, Huangfu D, Fontaine CC, Thompson CB, Finley LWS.

Nat Metab. 2019 Jul;1(7):676-687. doi: 10.1038/s42255-019-0082-3. Epub 2019 Jul 8.

PMID:
31511848
2.

Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency.

Li QV, Rosen BP, Huangfu D.

Wiley Interdiscip Rev Syst Biol Med. 2019 Aug 13:e1464. doi: 10.1002/wsbm.1464. [Epub ahead of print] Review.

PMID:
31407519
3.

Structures of two ArsR As(III)-responsive transcriptional repressors: Implications for the mechanism of derepression.

Prabaharan C, Kandavelu P, Packianathan C, Rosen BP, Thiyagarajan S.

J Struct Biol. 2019 Aug 1;207(2):209-217. doi: 10.1016/j.jsb.2019.05.009. Epub 2019 May 25.

PMID:
31136796
4.

Correlation of differential ascites volume with primary cytoreductive surgery outcome, lymph node involvement, and disease recurrence in advanced ovarian cancer.

Lai I, Daniel MN, Rosen BP, May T, Massey C, Feigenberg T.

Int J Gynecol Cancer. 2019 May 20. pii: ijgc-2019-000310. doi: 10.1136/ijgc-2019-000310. [Epub ahead of print]

PMID:
31113847
5.

Genome-scale screens identify JNK-JUN signaling as a barrier for pluripotency exit and endoderm differentiation.

Li QV, Dixon G, Verma N, Rosen BP, Gordillo M, Luo R, Xu C, Wang Q, Soh CL, Yang D, Crespo M, Shukla A, Xiang Q, Dündar F, Zumbo P, Witkin M, Koche R, Betel D, Chen S, Massagué J, Garippa R, Evans T, Beer MA, Huangfu D.

Nat Genet. 2019 Jun;51(6):999-1010. doi: 10.1038/s41588-019-0408-9. Epub 2019 May 20.

PMID:
31110351
6.

Role of ArsEFG in Roxarsone and Nitarsone Detoxification and Resistance.

Chen J, Zhang J, Rosen BP.

Environ Sci Technol. 2019 Jun 4;53(11):6182-6191. doi: 10.1021/acs.est.9b01187. Epub 2019 May 14.

PMID:
31059239
7.

Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic.

Nadar VS, Chen J, Dheeman DS, Galván AE, Yoshinaga-Sakurai K, Kandavelu P, Sankaran B, Kuramata M, Ishikawa S, Rosen BP, Yoshinaga M.

Commun Biol. 2019 Apr 15;2:131. doi: 10.1038/s42003-019-0365-y. eCollection 2019.

8.

Pathways of arsenic uptake and efflux.

Garbinski LD, Rosen BP, Chen J.

Environ Int. 2019 May;126:585-597. doi: 10.1016/j.envint.2019.02.058. Epub 2019 Mar 8. Review.

9.

Identification of Steps in the Pathway of Arsenosugar Biosynthesis.

Xue XM, Ye J, Raber G, Rosen BP, Francesconi K, Xiong C, Zhu Z, Rensing C, Zhu YG.

Environ Sci Technol. 2019 Jan 15;53(2):634-641. doi: 10.1021/acs.est.8b04389. Epub 2018 Dec 24.

PMID:
30525501
10.

The antibiotic action of methylarsenite is an emergent property of microbial communities.

Chen J, Yoshinaga M, Rosen BP.

Mol Microbiol. 2019 Feb;111(2):487-494. doi: 10.1111/mmi.14169. Epub 2018 Dec 5.

PMID:
30520200
11.

Directed Evolution of Saccharomyces cerevisiae for Increased Selenium Accumulation.

Yoshinaga M, How S, Blanco D, Murdoch IS, Grudny M, Powers SL, Molina N, Rosen BP, Welch AZ.

Microorganisms. 2018 Aug 6;6(3). pii: E81. doi: 10.3390/microorganisms6030081.

12.

The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.

Packianathan C, Kandavelu P, Rosen BP.

Biochemistry. 2018 Jul 17;57(28):4083-4092. doi: 10.1021/acs.biochem.8b00457. Epub 2018 Jun 26.

13.

Arsenic methylation by a genetically engineered Rhizobium-legume symbiont.

Zhang J, Xu Y, Cao T, Chen J, Rosen BP, Zhao FJ.

Plant Soil. 2017 Jul;416(1-2):259-269. doi: 10.1007/s11104-017-3207-z. Epub 2017 Feb 27.

14.

Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S-Adenosylmethionine Methyltransferase Reaction.

Packianathan C, Li J, Kandavelu P, Sankaran B, Rosen BP.

ACS Omega. 2018 Mar;3(3):3104-3112. doi: 10.1021/acsomega.8b00197. Epub 2018 Mar 14.

15.

Arsenic methylation by a novel ArsM As(III) S-adenosylmethionine methyltransferase that requires only two conserved cysteine residues.

Huang K, Xu Y, Packianathan C, Gao F, Chen C, Zhang J, Shen Q, Rosen BP, Zhao FJ.

Mol Microbiol. 2018 Jan;107(2):265-276. doi: 10.1111/mmi.13882. Epub 2017 Nov 23.

16.

Biochemical Characterization of ArsI: A Novel C-As Lyase for Degradation of Environmental Organoarsenicals.

Pawitwar SS, Nadar VS, Kandegedara A, Stemmler TL, Rosen BP, Yoshinaga M.

Environ Sci Technol. 2017 Oct 3;51(19):11115-11125. doi: 10.1021/acs.est.7b03180. Epub 2017 Sep 22.

17.

A novel MAs(III)-selective ArsR transcriptional repressor.

Chen J, Nadar VS, Rosen BP.

Mol Microbiol. 2017 Nov;106(3):469-478. doi: 10.1111/mmi.13826. Epub 2017 Sep 13.

18.

Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic.

Chen SC, Sun GX, Rosen BP, Zhang SY, Deng Y, Zhu BK, Rensing C, Zhu YG.

Sci Rep. 2017 Aug 10;7(1):7741. doi: 10.1038/s41598-017-08313-2.

19.

Linking Genes to Microbial Biogeochemical Cycling: Lessons from Arsenic.

Zhu YG, Xue XM, Kappler A, Rosen BP, Meharg AA.

Environ Sci Technol. 2017 Jul 5;51(13):7326-7339. doi: 10.1021/acs.est.7b00689. Epub 2017 Jun 23.

20.

Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity.

Li J, Packianathan C, Rossman TG, Rosen BP.

Chem Res Toxicol. 2017 Jul 17;30(7):1481-1491. doi: 10.1021/acs.chemrestox.7b00113. Epub 2017 Jun 19.

21.

Bacterial resistance to arsenic protects against protist killing.

Hao X, Li X, Pal C, Hobman J, Larsson DG, Saquib Q, Alwathnani HA, Rosen BP, Zhu YG, Rensing C.

Biometals. 2017 Apr;30(2):307-311. doi: 10.1007/s10534-017-0003-4. Epub 2017 Feb 16.

22.

Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus.

Chen J, Li J, Jiang X, Rosen BP.

Mol Microbiol. 2017 Apr;104(2):250-259. doi: 10.1111/mmi.13628. Epub 2017 Mar 13.

23.

The organoarsenical biocycle and the primordial antibiotic methylarsenite.

Li J, Pawitwar SS, Rosen BP.

Metallomics. 2016 Oct 1;8(10):1047-1055. doi: 10.1039/c6mt00168h. Review.

24.

Organoarsenical Biotransformations by Shewanella putrefaciens.

Chen J, Rosen BP.

Environ Sci Technol. 2016 Aug 2;50(15):7956-63. doi: 10.1021/acs.est.6b00235. Epub 2016 Jul 13.

25.

Efficient Arsenic Methylation and Volatilization Mediated by a Novel Bacterium from an Arsenic-Contaminated Paddy Soil.

Huang K, Chen C, Zhang J, Tang Z, Shen Q, Rosen BP, Zhao FJ.

Environ Sci Technol. 2016 Jun 21;50(12):6389-96. doi: 10.1021/acs.est.6b01974. Epub 2016 Jun 10.

26.

Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes.

Zhu Z, Li QV, Lee K, Rosen BP, González F, Soh CL, Huangfu D.

Cell Stem Cell. 2016 Jun 2;18(6):755-68. doi: 10.1016/j.stem.2016.03.015. Epub 2016 Apr 28.

27.

Structure of the ArsI C-As Lyase: Insights into the Mechanism of Degradation of Organoarsenical Herbicides and Growth Promoters.

Nadar VS, Yoshinaga M, Pawitwar SS, Kandavelu P, Sankaran B, Rosen BP.

J Mol Biol. 2016 Jun 5;428(11):2462-2473. doi: 10.1016/j.jmb.2016.04.022. Epub 2016 Apr 20.

28.

New mechanisms of bacterial arsenic resistance.

Yang HC, Rosen BP.

Biomed J. 2016 Feb;39(1):5-13. doi: 10.1016/j.bj.2015.08.003. Epub 2016 Apr 1. Review.

29.

Expression of arsenic resistance genes in the obligate anaerobe Bacteroides vulgatus ATCC 8482, a gut microbiome bacterium.

Li J, Mandal G, Rosen BP.

Anaerobe. 2016 Jun;39:117-23. doi: 10.1016/j.anaerobe.2016.03.012. Epub 2016 Mar 31.

30.

Inositol transporters AtINT2 and AtINT4 regulate arsenic accumulation in Arabidopsis seeds.

Duan GL, Hu Y, Schneider S, McDermott J, Chen J, Sauer N, Rosen BP, Daus B, Liu Z, Zhu YG.

Nat Plants. 2015 Dec 21;2(1):15202. doi: 10.1038/nplants.2015.202. eCollection 2016 Jan.

31.

Arsenic Methylation in Arabidopsis thaliana Expressing an Algal Arsenite Methyltransferase Gene Increases Arsenic Phytotoxicity.

Tang Z, Lv Y, Chen F, Zhang W, Rosen BP, Zhao FJ.

J Agric Food Chem. 2016 Apr 6;64(13):2674-81. doi: 10.1021/acs.jafc.6b00462. Epub 2016 Mar 28.

32.

Synergistic interaction of glyceraldehydes-3-phosphate dehydrogenase and ArsJ, a novel organoarsenical efflux permease, confers arsenate resistance.

Chen J, Yoshinaga M, Garbinski LD, Rosen BP.

Mol Microbiol. 2016 Jun;100(6):945-53. doi: 10.1111/mmi.13371. Epub 2016 Apr 20.

33.

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.

Kumar NV, Yang J, Pillai JK, Rawat S, Solano C, Kumar A, Grøtli M, Stemmler TL, Rosen BP, Tamás MJ.

Mol Cell Biol. 2015 Dec 28;36(6):913-22. doi: 10.1128/MCB.00842-15.

34.

Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT).

Dong H, Madegowda M, Nefzi A, Houghten RA, Giulianotti MA, Rosen BP.

Chem Res Toxicol. 2015 Dec 21;28(12):2419-25. doi: 10.1021/acs.chemrestox.5b00432. Epub 2015 Dec 6.

35.
36.

ArsP: a methylarsenite efflux permease.

Chen J, Madegowda M, Bhattacharjee H, Rosen BP.

Mol Microbiol. 2015 Nov;98(4):625-35. doi: 10.1111/mmi.13145. Epub 2015 Aug 22.

37.

Genetically Engineering Bacillus subtilis with a Heat-Resistant Arsenite Methyltransferase for Bioremediation of Arsenic-Contaminated Organic Waste.

Huang K, Chen C, Shen Q, Rosen BP, Zhao FJ.

Appl Environ Microbiol. 2015 Oct;81(19):6718-24. doi: 10.1128/AEM.01535-15. Epub 2015 Jul 17.

38.

Draft Genome Sequence of Burkholderia sp. MR1, a Methylarsenate-Reducing Bacterial Isolate from Florida Golf Course Soil.

Pawitwar SS, Utturkar SM, Brown SD, Yoshinaga M, Rosen BP.

Genome Announc. 2015 Jun 4;3(3). pii: e00608-15. doi: 10.1128/genomeA.00608-15.

39.

Draft Genome Sequence of Brevibacterium linens AE038-8, an Extremely Arsenic-Resistant Bacterium.

Maizel D, Utturkar SM, Brown SD, Ferrero MA, Rosen BP.

Genome Announc. 2015 Apr 16;3(2). pii: e00316-15. doi: 10.1128/genomeA.00316-15.

40.

High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity.

Dong H, Xu W, Pillai JK, Packianathan C, Rosen BP.

Anal Biochem. 2015 Jul 1;480:67-73. doi: 10.1016/j.ab.2015.04.011. Epub 2015 Apr 10.

41.

A disulfide-bond cascade mechanism for arsenic(III) S-adenosylmethionine methyltransferase.

Marapakala K, Packianathan C, Ajees AA, Dheeman DS, Sankaran B, Kandavelu P, Rosen BP.

Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):505-15. doi: 10.1107/S1399004714027552. Epub 2015 Feb 26.

42.
43.

Arsenic methylation and volatilization by arsenite S-adenosylmethionine methyltransferase in Pseudomonas alcaligenes NBRC14159.

Zhang J, Cao T, Tang Z, Shen Q, Rosen BP, Zhao FJ.

Appl Environ Microbiol. 2015 Apr;81(8):2852-60. doi: 10.1128/AEM.03804-14. Epub 2015 Feb 13.

44.

Biosensors for inorganic and organic arsenicals.

Chen J, Rosen BP.

Biosensors (Basel). 2014 Nov 25;4(4):494-512. doi: 10.3390/bios4040494. eCollection 2014 Dec. Review.

45.

Response to the letter to the editor regarding our article (Dheeman et al., 2014).

Dheeman DS, Packianathana C, Pillai JK, Rosen BP.

Chem Res Toxicol. 2014 Dec 15;27(12):2012. doi: 10.1021/tx500439e. Epub 2014 Nov 10. No abstract available.

PMID:
25383697
46.

Pathway of human AS3MT arsenic methylation.

Dheeman DS, Packianathan C, Pillai JK, Rosen BP.

Chem Res Toxicol. 2014 Nov 17;27(11):1979-89. doi: 10.1021/tx500313k. Epub 2014 Oct 30.

47.

Crystallization and preliminary X-ray crystallographic studies of CrArsM, an arsenic(III) S-adenosylmethionine methyltransferase from Chlamydomonas reinhardtii.

Packianathan C, Pillai JK, Riaz A, Kandavelu P, Sankaran B, Rosen BP.

Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1385-8. doi: 10.1107/S2053230X14018469. Epub 2014 Sep 25.

48.

Mutations in the ArsA ATPase that restore interaction with the ArsD metallochaperone.

Pillai JK, Venkadesh S, Ajees AA, Rosen BP, Bhattacharjee H.

Biometals. 2014 Dec;27(6):1263-75. doi: 10.1007/s10534-014-9788-6. Epub 2014 Sep 3.

49.

Volatilization of arsenic from polluted soil by Pseudomonas putida engineered for expression of the arsM Arsenic(III) S-adenosine methyltransferase gene.

Chen J, Sun GX, Wang XX, Lorenzo Vd, Rosen BP, Zhu YG.

Environ Sci Technol. 2014 Sep 2;48(17):10337-44. doi: 10.1021/es502230b. Epub 2014 Aug 14.

50.

Structure of Escherichia coli Grx2 in complex with glutathione: a dual-function hybrid of glutaredoxin and glutathione S-transferase.

Ye J, Nadar SV, Li J, Rosen BP.

Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1907-13. doi: 10.1107/S1399004714009250. Epub 2014 Jun 29.

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