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Depressive symptoms and cerebral microvascular disease in adults with Type 1 diabetes mellitus.

Nunley KA, Karp JF, Orchard TJ, Costacou T, Aizenstein HJ, Jennings JR, Rosano C.

Diabet Med. 2018 Dec 15. doi: 10.1111/dme.13879. [Epub ahead of print]


Neural correlates of perceived physical and mental fatigability in older adults: A pilot study.

Wasson E, Rosso AL, Santanasto AJ, Rosano C, Butters MA, Rejeski WJ, Boudreau RM, Aizenstein H, Gmelin T, Glynn NW; LIFE Study Group.

Exp Gerontol. 2019 Jan;115:139-147. doi: 10.1016/j.exger.2018.12.003. Epub 2018 Dec 4.


Greater progression of coronary artery calcification is associated with clinically relevant cognitive impairment in type 1 diabetes.

Guo J, Nunley KA, Costacou T, Miller RG, Rosano C, Edmundowicz D, Orchard TJ.

Atherosclerosis. 2019 Jan;280:58-65. doi: 10.1016/j.atherosclerosis.2018.11.003. Epub 2018 Nov 8.


Sex-dependent effect of the BDNF Val66Met polymorphism on executive functioning and processing speed in older adults: evidence from the health ABC study.

Barha CK, Liu-Ambrose T, Best JR, Yaffe K, Rosano C; Health, Aging and Body Composition Study.

Neurobiol Aging. 2019 Feb;74:161-170. doi: 10.1016/j.neurobiolaging.2018.10.021. Epub 2018 Oct 23.


Vision Impairment and Cognitive Outcomes in Older Adults: The Health ABC Study.

Swenor BK, Wang J, Varadaraj V, Rosano C, Yaffe K, Albert M, Simonsick EM.

J Gerontol A Biol Sci Med Sci. 2018 Oct 25. doi: 10.1093/gerona/gly244. [Epub ahead of print]


Inhibition of Human Topoisomerase II by N,N,N-Trimethylethanammonium Iodide Alkylcarbazole Derivatives.

Saturnino C, Caruso A, Iacopetta D, Rosano C, Ceramella J, Muià N, Mariconda A, Bonomo MG, Ponassi M, Rosace G, Sinicropi MS, Longo P.

ChemMedChem. 2018 Dec 20;13(24):2635-2643. doi: 10.1002/cmdc.201800546. Epub 2018 Nov 30.


Hydrophilic and amphiphilic water-soluble dendrimer prodrugs suitable for parenteral administration of a non-soluble non-nucleoside HIV-1 reverse transcriptase inhibitor thiocarbamate derivative.

Alfei S, Catena S, Ponassi M, Rosano C, Zoppi V, Spallarossa A.

Eur J Pharm Sci. 2018 Nov 1;124:153-164. doi: 10.1016/j.ejps.2018.08.036. Epub 2018 Aug 28.


Neuroimaging correlates of lateral postural control in older ambulatory adults.

Massa RE, Rosso A, Metti AL, Sparto PJ, Aizenstein H, Ferrucci L, Divecha A, Rosano C; Health ABC Study.

Aging Clin Exp Res. 2018 Aug 28. doi: 10.1007/s40520-018-1028-4. [Epub ahead of print]


Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA).

Montero-Odasso M, Almeida QJ, Bherer L, Burhan AM, Camicioli R, Doyon J, Fraser S, Muir-Hunter S, Li KZH, Liu-Ambrose T, McIlroy W, Middleton L, Morais JA, Sakurai R, Speechley M, Vasudev A, Beauchet O, Hausdorff JM, Rosano C, Studenski S, Verghese J; Canadian Gait and Cognition Network.

J Gerontol A Biol Sci Med Sci. 2018 Jun 21. doi: 10.1093/gerona/gly148. [Epub ahead of print]


A novel calix[4]pyrrole derivative as a potential anticancer agent that forms genotoxic adducts with DNA.

Geretto M, Ponassi M, Casale M, Pulliero A, Cafeo G, Malagreca F, Profumo A, Balza E, Bersimbaev R, Kohnke FH, Rosano C, Izzotti A.

Sci Rep. 2018 Jul 23;8(1):11075. doi: 10.1038/s41598-018-29314-9.


Dopamine-Related Genotypes and Physical Activity Change During an Intervention: The Lifestyle Interventions and Independence for Elders Study.

Rosso AL, Metti AL, Glynn NW, Boudreau RM, Rejeski WJ, Bohnen N, Chen H, Johannsen NM, King AC, Manini TM, Pahor M, Studenski SA, Fragoso CAV, Rosano C; LIFE Study Group.

J Am Geriatr Soc. 2018 Jul;66(6):1172-1179. doi: 10.1111/jgs.15369. Epub 2018 Apr 10.


Association of Hippocampal Substructure Resting-State Functional Connectivity with Memory Performance in Older Adults.

Smagula SF, Karim HT, Rangarajan A, Santos FP, Wood SC, Santini T, Jakicic JM, Reynolds CF 3rd, Cameron JL, Vallejo AN, Butters MA, Rosano C, Ibrahim TS, Erickson KI, Aizenstein HJ.

Am J Geriatr Psychiatry. 2018 Jun;26(6):690-699. doi: 10.1016/j.jagp.2018.03.003. Epub 2018 Mar 13.


Predicting Dementia from Decline in Gait Speed: Are We There Yet?

Rosano C, Snitz BE.

J Am Geriatr Soc. 2018 Sep;66(9):1659-1660. doi: 10.1111/jgs.15368. Epub 2018 Apr 2. No abstract available.


Longitudinal changes in physical function and physical activity in older adults.

Metti AL, Best JR, Shaaban CE, Ganguli M, Rosano C.

Age Ageing. 2018 Mar 13. doi: 10.1093/ageing/afy025. [Epub ahead of print]


Localization-controlled two-color luminescence imaging via environmental modulation of energy transfer in a multichromophoric species.

Bonaccorsi P, Papalia T, Barattucci A, Salerno TMG, Rosano C, Castagnola P, Viale M, Monticone M, Campagna S, Puntoriero F.

Dalton Trans. 2018 Mar 26;47(13):4733-4738. doi: 10.1039/c7dt04850e.


Long-term changes in retinal vascular diameter and cognitive impairment in type 1 diabetes.

Nunley KA, Metti AL, Klein R, Klein BE, Saxton JA, Orchard TJ, Costacou T, Aizenstein HJ, Rosano C.

Diab Vasc Dis Res. 2018 May;15(3):223-232. doi: 10.1177/1479164118758581. Epub 2018 Feb 28.


A population neuroscience approach to the study of cerebral small vessel disease in midlife and late life: an invited review.

Jorgensen DR, Shaaban CE, Wiley CA, Gianaros PJ, Mettenburg J, Rosano C.

Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1117-H1136. doi: 10.1152/ajpheart.00535.2017. Epub 2018 Feb 2. Review.


N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation.

Sinicropi MS, Iacopetta D, Rosano C, Randino R, Caruso A, Saturnino C, Muià N, Ceramella J, Puoci F, Rodriquez M, Longo P, Plutino MR.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):434-444. doi: 10.1080/14756366.2017.1419216.


Disease severity and slower psychomotor speed in adults with sickle cell disease.

Jorgensen DR, Metti A, Butters MA, Mettenburg JM, Rosano C, Novelli EM.

Blood Adv. 2017 Sep 14;1(21):1790-1795. doi: 10.1182/bloodadvances.2017008219. eCollection 2017 Sep 26.


Late-Life Depressive Symptoms as Partial Mediators in the Associations between Subclinical Cardiovascular Disease with Onset of Mild Cognitive Impairment and Dementia.

Armstrong NM, Carlson MC, Schrack J, Xue QL, Carnethon MR, Rosano C, Chaves PHM, Gross AL.

Am J Geriatr Psychiatry. 2018 May;26(5):559-568. doi: 10.1016/j.jagp.2017.11.004. Epub 2017 Nov 20.


Vascular and dopaminergic contributors to mild parkinsonian signs in older adults.

Rosso AL, Bohnen NI, Launer LJ, Aizenstein HJ, Yaffe K, Rosano C.

Neurology. 2018 Jan 16;90(3):e223-e229. doi: 10.1212/WNL.0000000000004842. Epub 2017 Dec 15.


The relationship of health literacy to diabetes status differs by sex in older adults.

Quartuccio M, Simonsick EM, Langan S, Harris T, Sudore RL, Thorpe R, Rosano C, Hill-Briggs F, Golden S, Kalyani RR.

J Diabetes Complications. 2018 Apr;32(4):368-372. doi: 10.1016/j.jdiacomp.2017.10.012. Epub 2017 Oct 28.


Cognitive Performance Does not Limit Physical Activity Participation in the Lifestyle Interventions and Independence for Elders Pilot Study (LIFE-P).

Reid KF, Walkup MP, Katula JA, Sink KM, Anton S, Axtell R, Kerwin DR, King AC, Kramer F, Miller ME, Myers V, Rosano C, Studenski SA, Lopez OL, Verghese J, Fielding RA, Williamson J.

J Prev Alzheimers Dis. 2017;4(1):44-50. doi: 10.14283/jpad.2016.107.


Basal ganglia cerebral blood flow associates with psychomotor speed in adults with type 1 diabetes.

Ryan JP, Aizenstein HJ, Orchard TJ, Nunley KA, Karim H, Rosano C.

Brain Imaging Behav. 2018 Oct;12(5):1271-1278. doi: 10.1007/s11682-017-9783-y.


New insights for the use of quercetin analogs in cancer treatment.

Iacopetta D, Grande F, Caruso A, Mordocco RA, Plutino MR, Scrivano L, Ceramella J, Muià N, Saturnino C, Puoci F, Rosano C, Sinicropi MS.

Future Med Chem. 2017 Nov;9(17):2011-2028. doi: 10.4155/fmc-2017-0118. Epub 2017 Oct 27.


Longitudinal Associations Between Walking Speed and Amount of Self-reported Time Spent Walking Over a 9-Year Period in Older Women and Men.

Best JR, Liu-Ambrose T, Metti AL, Rosso AL, Satterfield S, Studenski S, Newman AB, Rosano C; Health, Aging and Body Composition Study.

J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1265-1271. doi: 10.1093/gerona/glx129.


Contributions to lateral balance control in ambulatory older adults.

Sparto PJ, Newman AB, Simonsick EM, Caserotti P, Strotmeyer ES, Kritchevsky SB, Yaffe K, Rosano C; Health ABC Study.

Aging Clin Exp Res. 2018 Jun;30(6):633-641. doi: 10.1007/s40520-017-0819-3. Epub 2017 Aug 23.


In Vivo Imaging of Venous Side Cerebral Small-Vessel Disease in Older Adults: An MRI Method at 7T.

Shaaban CE, Aizenstein HJ, Jorgensen DR, MacCloud RL, Meckes NA, Erickson KI, Glynn NW, Mettenburg J, Guralnik J, Newman AB, Ibrahim TS, Laurienti PJ, Vallejo AN, Rosano C; LIFE Study Group.

AJNR Am J Neuroradiol. 2017 Oct;38(10):1923-1928. doi: 10.3174/ajnr.A5327. Epub 2017 Aug 3.


Statin use and cognitive function in middle-aged adults with type 1 diabetes.

Nunley KA, Orchard TJ, Ryan CM, Miller R, Costacou T, Rosano C.

World J Diabetes. 2017 Jun 15;8(6):286-296. doi: 10.4239/wjd.v8.i6.286.


Resistance to cancer chemotherapeutic drugs is determined by pivotal microRNA regulators.

Geretto M, Pulliero A, Rosano C, Zhabayeva D, Bersimbaev R, Izzotti A.

Am J Cancer Res. 2017 Jun 1;7(6):1350-1371. eCollection 2017.


Slowing gait and risk for cognitive impairment: The hippocampus as a shared neural substrate.

Rosso AL, Verghese J, Metti AL, Boudreau RM, Aizenstein HJ, Kritchevsky S, Harris T, Yaffe K, Satterfield S, Studenski S, Rosano C.

Neurology. 2017 Jul 25;89(4):336-342. doi: 10.1212/WNL.0000000000004153. Epub 2017 Jun 28.


Long-term changes in time spent walking and subsequent cognitive and structural brain changes in older adults.

Best JR, Rosano C, Aizenstein HJ, Tian Q, Boudreau RM, Ayonayon HN, Satterfield S, Simonsick EM, Studenski S, Yaffe K, Liu-Ambrose T; Health, Aging and Body Composition Study.

Neurobiol Aging. 2017 Sep;57:153-161. doi: 10.1016/j.neurobiolaging.2017.05.023. Epub 2017 Jun 6.


Catechol-O-Methyltransferase Genotype and Gait Speed Changes over 10 Years in Older Adults.

Metti AL, Rosano C, Boudreau R, Massa R, Yaffe K, Satterfield S, Harris T, Rosso AL.

J Am Geriatr Soc. 2017 Sep;65(9):2016-2022. doi: 10.1111/jgs.14980. Epub 2017 Jun 22.


Associations of Musculoskeletal Pain With Mobility in Older Adults: Potential Cerebral Mechanisms.

Cruz-Almeida Y, Rosso A, Marcum Z, Harris T, Newman AB, Nevitt M, Satterfield S, Yaffe K, Rosano C; Health ABC Study.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1270-1276. doi: 10.1093/gerona/glx084.


Corrigendum to "Brain Activation and Psychomotor Speed in Middle-Aged Patients with Type 1 Diabetes: Relationships with Hyperglycemia and Brain Small Vessel Disease".

Hwang M, Tudorascu DL, Nunley K, Karim H, Aizenstein HJ, Orchard TJ, Rosano C.

J Diabetes Res. 2017;2017:4295645. doi: 10.1155/2017/4295645. Epub 2017 Mar 16.


Cognitive Status, Gray Matter Atrophy, and Lower Orthostatic Blood Pressure in Older Adults.

O'Hare C, Kenny RA, Aizenstein H, Boudreau R, Newman A, Launer L, Satterfield S, Yaffe K, Rosano C; Health ABC Study.

J Alzheimers Dis. 2017;57(4):1239-1250. doi: 10.3233/JAD-161228.


Physical activity and hippocampal volume in middle-aged patients with type 1 diabetes.

Nunley KA, Leckie RL, Orchard TJ, Costacou T, Aizenstein HJ, Jennings JR, Erickson KI, Rosano C.

Neurology. 2017 Apr 18;88(16):1564-1570. doi: 10.1212/WNL.0000000000003805. Epub 2017 Mar 10.


Natural antimicrobial peptide complexes in the fighting of antibiotic resistant biofilms: Calliphora vicina medicinal maggots.

Gordya N, Yakovlev A, Kruglikova A, Tulin D, Potolitsina E, Suborova T, Bordo D, Rosano C, Chernysh S.

PLoS One. 2017 Mar 9;12(3):e0173559. doi: 10.1371/journal.pone.0173559. eCollection 2017.


Synthesis of short retinoidal amides related to fenretinide: antioxidant activities and differentiation-inducing ability.

Anzaldi M, Viale M, Macciò C, Castagnola P, Oliveri V, Rosano C, Balbi A.

Cancer Chemother Pharmacol. 2017 Apr;79(4):725-736. doi: 10.1007/s00280-017-3265-1. Epub 2017 Mar 9.


Effects on Energy Metabolism of Two Guanidine Molecules, (Boc)2 -Creatine and Metformin.

Garbati P, Ravera S, Scarfì S, Salis A, Rosano C, Poggi A, Damonte G, Millo E, Balestrino M.

J Cell Biochem. 2017 Sep;118(9):2700-2711. doi: 10.1002/jcb.25914. Epub 2017 Feb 13.


Regional Gray Matter Volumes as Related to Psychomotor Slowing in Adults with Type 1 Diabetes.

Nunley KA, Ryan CM, Aizenstein HJ, Jennings JR, MacCloud RL, Orchard TJ, Rosano C.

Psychosom Med. 2017 Jun;79(5):533-540. doi: 10.1097/PSY.0000000000000449.


Hippocampal Response to a 24-Month Physical Activity Intervention in Sedentary Older Adults.

Rosano C, Guralnik J, Pahor M, Glynn NW, Newman AB, Ibrahim TS, Erickson K, Cohen R, Shaaban CE, MacCloud RL, Aizenstein HJ.

Am J Geriatr Psychiatry. 2017 Mar;25(3):209-217. doi: 10.1016/j.jagp.2016.11.007. Epub 2016 Nov 15.


Tracking protons from respiratory chain complexes to ATP synthase c-subunit: The critical role of serine and threonine residues.

Panfoli I, Ponassi M, Ravera S, Calzia D, Beitia M, Morelli A, Rosano C.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):922-927. doi: 10.1016/j.bbrc.2016.11.134. Epub 2016 Nov 25.


N-heterocyclic carbene complexes of silver and gold as novel tools against breast cancer progression.

Saturnino C, Barone I, Iacopetta D, Mariconda A, Sinicropi MS, Rosano C, Campana A, Catalano S, Longo P, Andò S.

Future Med Chem. 2016 Dec;8(18):2213-2229. Epub 2016 Nov 22.


Contributors to Poor Mobility in Older Adults: Integrating White Matter Hyperintensities and Conditions Affecting Other Systems.

Rosso AL, Studenski SA, Longstreth WT Jr, Brach JS, Boudreau RM, Rosano C.

J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1246-1251. doi: 10.1093/gerona/glw224.


Multifaceted properties of 1,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitors.

Iacopetta D, Rosano C, Puoci F, Parisi OI, Saturnino C, Caruso A, Longo P, Ceramella J, Malzert-Fréon A, Dallemagne P, Rault S, Sinicropi MS.

Eur J Pharm Sci. 2017 Jan 1;96:263-272. doi: 10.1016/j.ejps.2016.09.039. Epub 2016 Oct 1.


Slow gait, white matter characteristics, and prior 10-year interleukin-6 levels in older adults.

Nadkarni NK, Boudreau RM, Studenski SA, Lopez OL, Liu G, Kritchevsky S, Yaffe K, Newman AB, Rosano C.

Neurology. 2016 Nov 8;87(19):1993-1999. Epub 2016 Oct 12.


Neurocognitive consequences of diabetes.

Ryan CM, van Duinkerken E, Rosano C.

Am Psychol. 2016 Oct;71(7):563-576. Review.


Can Neuroimaging Markers of Vascular Pathology Explain Cognitive Performance in Adults With Sickle Cell Anemia? A review of the Literature.

Jorgensen DR, Rosano C, Novelli EM.

Hemoglobin. 2016 Nov;40(6):381-387. doi: 10.1080/03630269.2016.1242493. Review.



Rosano C, Ikram MA, Ganguli M.

Handb Clin Neurol. 2016;138:ix-x. doi: 10.1016/B978-0-12-802973-2.09987-0. No abstract available.


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