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Items: 10

1.

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K.

Bushell SR, Pike ACW, Falzone ME, Rorsman NJG, Ta CM, Corey RA, Newport TD, Christianson JC, Scofano LF, Shintre CA, Tessitore A, Chu A, Wang Q, Shrestha L, Mukhopadhyay SMM, Love JD, Burgess-Brown NA, Sitsapesan R, Stansfeld PJ, Huiskonen JT, Tammaro P, Accardi A, Carpenter EP.

Nat Commun. 2019 Sep 2;10(1):3956. doi: 10.1038/s41467-019-11753-1.

2.

Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.

Vergari E, Knudsen JG, Ramracheya R, Salehi A, Zhang Q, Adam J, Asterholm IW, Benrick A, Briant LJB, Chibalina MV, Gribble FM, Hamilton A, Hastoy B, Reimann F, Rorsman NJG, Spiliotis II, Tarasov A, Wu Y, Ashcroft FM, Rorsman P.

Nat Commun. 2019 Jan 11;10(1):139. doi: 10.1038/s41467-018-08193-8.

3.

CPT1a-Dependent Long-Chain Fatty Acid Oxidation Contributes to Maintaining Glucagon Secretion from Pancreatic Islets.

Briant LJB, Dodd MS, Chibalina MV, Rorsman NJG, Johnson PRV, Carmeliet P, Rorsman P, Knudsen JG.

Cell Rep. 2018 Jun 12;23(11):3300-3311. doi: 10.1016/j.celrep.2018.05.035.

4.

Defining the ionic mechanisms of optogenetic control of vascular tone by channelrhodopsin-2.

Rorsman NJG, Ta CM, Garnett H, Swietach P, Tammaro P.

Br J Pharmacol. 2018 Jun;175(11):2028-2045. doi: 10.1111/bph.14183. Epub 2018 Apr 17.

5.

Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes.

Adam J, Ramracheya R, Chibalina MV, Ternette N, Hamilton A, Tarasov AI, Zhang Q, Rebelato E, Rorsman NJG, Martín-Del-Río R, Lewis A, Özkan G, Do HW, Spégel P, Saitoh K, Kato K, Igarashi K, Kessler BM, Pugh CW, Tamarit-Rodriguez J, Mulder H, Clark A, Frizzell N, Soga T, Ashcroft FM, Silver A, Pollard PJ, Rorsman P.

Cell Rep. 2017 Sep 26;20(13):3135-3148. doi: 10.1016/j.celrep.2017.08.093.

6.

Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.

Ta CM, Acheson KE, Rorsman NJG, Jongkind RC, Tammaro P.

Br J Pharmacol. 2017 Sep;174(18):2984-2999. doi: 10.1111/bph.13913. Epub 2017 Aug 10.

7.

Mechanism of allosteric activation of TMEM16A/ANO1 channels by a commonly used chloride channel blocker.

Ta CM, Adomaviciene A, Rorsman NJ, Garnett H, Tammaro P.

Br J Pharmacol. 2016 Feb;173(3):511-28. doi: 10.1111/bph.13381. Epub 2016 Jan 18.

8.

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

Zhang Q, Chibalina MV, Bengtsson M, Groschner LN, Ramracheya R, Rorsman NJ, Leiss V, Nassar MA, Welling A, Gribble FM, Reimann F, Hofmann F, Wood JN, Ashcroft FM, Rorsman P.

J Physiol. 2014 Nov 1;592(21):4677-96. doi: 10.1113/jphysiol.2014.274209. Epub 2014 Aug 28.

9.

ATP-regulated potassium channels and voltage-gated calcium channels in pancreatic alpha and beta cells: similar functions but reciprocal effects on secretion.

Rorsman P, Ramracheya R, Rorsman NJ, Zhang Q.

Diabetologia. 2014 Sep;57(9):1749-61. doi: 10.1007/s00125-014-3279-8. Epub 2014 Jun 7. Review.

PMID:
24906950
10.

Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.

Zhang Q, Ramracheya R, Lahmann C, Tarasov A, Bengtsson M, Braha O, Braun M, Brereton M, Collins S, Galvanovskis J, Gonzalez A, Groschner LN, Rorsman NJ, Salehi A, Travers ME, Walker JN, Gloyn AL, Gribble F, Johnson PR, Reimann F, Ashcroft FM, Rorsman P.

Cell Metab. 2013 Dec 3;18(6):871-82. doi: 10.1016/j.cmet.2013.10.014.

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