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Items: 25


Anti-ADAMTS13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura do not hamper ELISA-based quantification of ADAMTS13 antigen.

Dekimpe C, Roose E, Tersteeg C, Joly BS, Dewaele A, Horta S, Pareyn I, Vandenbulcke A, Deckmyn H, Feys HB, Tellier E, Kaplanski G, Scully M, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K.

J Thromb Haemost. 2020 Jan 27. doi: 10.1111/jth.14747. [Epub ahead of print]


Transfer of ADAMTS13 antibody-mediated thrombotic thrombocytopenic purpura via kidney transplantation.

Zafrani L, Dekimpe C, Joly BS, Roose E, Fieux F, Azoulay E, Peraldi MN, Durrbach A, Coppo P, Vanhoorelbeke K, Veyradier A.

Haematologica. 2019 Jun;104(6):e277-e280. doi: 10.3324/haematol.2019.219063. Epub 2019 Feb 28. No abstract available.


Generation of anti-idiotypic antibodies to detect anti-spacer antibody idiotopes in acute thrombotic thrombocytopenic purpura patients.

Schelpe AS, Roose E, Joly BS, Pareyn I, Mancini I, Biganzoli M, Deckmyn H, Voorberg J, Fijnheer R, Peyvandi F, De Meyer SF, Coppo P, Veyradier A, Vanhoorelbeke K.

Haematologica. 2019 Jun;104(6):1268-1276. doi: 10.3324/haematol.2018.205666. Epub 2018 Dec 6.


ADAMTS13 Gene Mutations Influence ADAMTS13 Conformation and Disease Age-Onset in the French Cohort of Upshaw-Schulman Syndrome.

Joly BS, Boisseau P, Roose E, Stepanian A, Biebuyck N, Hogan J, Provot F, Delmas Y, Garrec C, Vanhoorelbeke K, Coppo P, Veyradier A; French Reference Center for Thrombotic Microangiopathies.

Thromb Haemost. 2018 Nov;118(11):1902-1917. doi: 10.1055/s-0038-1673686. Epub 2018 Oct 12.


Anti-ADAMTS13 Autoantibodies against Cryptic Epitopes in Immune-Mediated Thrombotic Thrombocytopenic Purpura.

Roose E, Vidarsson G, Kangro K, Verhagen OJHM, Mancini I, Desender L, Pareyn I, Vandeputte N, Vandenbulcke A, Vendramin C, Schelpe AS, Voorberg J, Azerad MA, Gilardin L, Scully M, Dierickx D, Deckmyn H, De Meyer SF, Peyvandi F, Vanhoorelbeke K.

Thromb Haemost. 2018 Oct;118(10):1729-1742. doi: 10.1055/s-0038-1669459. Epub 2018 Sep 20.


Preemptive rituximab prevents long-term relapses in immune-mediated thrombotic thrombocytopenic purpura.

Jestin M, Benhamou Y, Schelpe AS, Roose E, Provôt F, Galicier L, Hié M, Presne C, Poullin P, Wynckel A, Saheb S, Deligny C, Servais A, Girault S, Delmas Y, Kanouni T, Lautrette A, Chauveau D, Mousson C, Perez P, Halimi JM, Charvet-Rumpler A, Hamidou M, Cathébras P, Vanhoorelbeke K, Veyradier A, Coppo P; French Thrombotic Microangiopathies Reference Center.

Blood. 2018 Nov 15;132(20):2143-2153. doi: 10.1182/blood-2018-04-840090. Epub 2018 Sep 10.


Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13.

Schelpe AS, Orlando C, Ercig B, Geeroms C, Pareyn I, Vandeputte N, Velásquez Pereira LC, Roose E, Fostier K, Nicolaes GAF, Deckmyn H, De Meyer SF, Vanhoorelbeke K, Jochmans K.

Eur J Haematol. 2018 May 15. doi: 10.1111/ejh.13094. [Epub ahead of print]


Anti-ADAMTS13 Antibodies and a Novel Heterozygous p.R1177Q Mutation in a Case of Pregnancy-Onset Immune-Mediated Thrombotic Thrombocytopenic Purpura.

Roose E, Tersteeg C, Demeersseman R, Schelpe AS, Deforche L, Pareyn I, Vandenbulcke A, Vandeputte N, Dierickx D, Voorberg J, Deckmyn H, De Meyer SF, Vanhoorelbeke K.

TH Open. 2018 Jan 8;2(1):e8-e15. doi: 10.1055/s-0037-1615252. eCollection 2018 Jan.


An open conformation of ADAMTS-13 is a hallmark of acute acquired thrombotic thrombocytopenic purpura.

Roose E, Schelpe AS, Joly BS, Peetermans M, Verhamme P, Voorberg J, Greinacher A, Deckmyn H, De Meyer SF, Coppo P, Veyradier A, Vanhoorelbeke K.

J Thromb Haemost. 2018 Feb;16(2):378-388. doi: 10.1111/jth.13922. Epub 2018 Jan 23.


Platelet rescue by macrophage depletion in obese ADAMTS-13-deficient mice at risk of thrombotic thrombocytopenic purpura.

Geys L, Roose E, Scroyen I, Rottensteiner H, Tersteeg C, Hoylaerts MF, Vanhoorelbeke K, Lijnen HR.

J Thromb Haemost. 2018 Jan;16(1):150-163. doi: 10.1111/jth.13901. Epub 2017 Nov 28.


Role of ADAMTS13 in diet-induced liver steatosis.

Geys L, Roose E, Vanhoorelbeke K, Bedossa P, Scroyen I, Lijnen HR.

Mol Med Rep. 2017 Aug;16(2):1451-1458. doi: 10.3892/mmr.2017.6714. Epub 2017 Jun 7.


ADAMTS13 deficiency promotes microthrombosis in a murine model of diet-induced liver steatosis.

Geys L, Bauters D, Roose E, Tersteeg C, Vanhoorelbeke K, Hoylaerts MF, Lijnen RH, Scroyen I.

Thromb Haemost. 2017 Jan 5;117(1):19-26. doi: 10.1160/TH16-03-0195. Epub 2016 Sep 8.


Generation of Anti-Murine ADAMTS13 Antibodies and Their Application in a Mouse Model for Acquired Thrombotic Thrombocytopenic Purpura.

Deforche L, Tersteeg C, Roose E, Vandenbulcke A, Vandeputte N, Pareyn I, De Cock E, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K.

PLoS One. 2016 Aug 1;11(8):e0160388. doi: 10.1371/journal.pone.0160388. eCollection 2016.


ADAMTS13 and anti-ADAMTS13 autoantibodies in thrombotic thrombocytopenic purpura - current perspectives and new treatment strategies.

Tersteeg C, Verhenne S, Roose E, Schelpe AS, Deckmyn H, De Meyer SF, Vanhoorelbeke K.

Expert Rev Hematol. 2016;9(2):209-21. doi: 10.1586/17474086.2016.1122515. Epub 2015 Dec 8. Review.


Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.

Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K.

J Thromb Haemost. 2015 Nov;13(11):2063-75. doi: 10.1111/jth.13149. Epub 2015 Oct 20.


ADAMTS13 deficiency in mice does not affect adipose tissue development.

Geys L, Scroyen I, Roose E, Vanhoorelbeke K, Lijnen HR.

Biochim Biophys Acta. 2015 Jul;1850(7):1368-74. doi: 10.1016/j.bbagen.2015.03.008. Epub 2015 Mar 24.


Inuvialuit adults in the Canadian Arctic have a high body mass index and self-reported physical activity.

Hopping BN, Erber E, Beck L, De Roose E, Sharma S.

J Hum Nutr Diet. 2010 Oct;23 Suppl 1:115-9. doi: 10.1111/j.1365-277X.2010.01103.x.


Important psychosocial factors to target in nutrition interventions to improve diet in Inuvialuit communities in the Canadian Arctic.

Mead E, Gittelsohn J, De Roose E, Sharma S.

J Hum Nutr Diet. 2010 Oct;23 Suppl 1:92-9. doi: 10.1111/j.1365-277X.2010.01095.x.


Food patterns and socioeconomic indicators of food consumption amongst Inuvialuit in the Canadian Arctic.

Erber E, Beck L, Hopping BN, Sheehy T, De Roose E, Sharma S.

J Hum Nutr Diet. 2010 Oct;23 Suppl 1:59-66. doi: 10.1111/j.1365-277X.2010.01097.x.


Prevalence and risk factors for self-reported chronic disease amongst Inuvialuit populations.

Erber E, Beck L, De Roose E, Sharma S.

J Hum Nutr Diet. 2010 Oct;23 Suppl 1:43-50. doi: 10.1111/j.1365-277X.2010.01092.x.


Assessment of dietary adequacy in a remote Inuvialuit population.

Erber E, Hopping BN, Beck L, Sheehy T, De Roose E, Sharma S.

J Hum Nutr Diet. 2010 Oct;23 Suppl 1:35-42. doi: 10.1111/j.1365-277X.2010.01098.x.


Dietary intake in a population undergoing a rapid transition in diet and lifestyle: the Inuvialuit in the Northwest Territories of Arctic Canada.

Sharma S, De Roose E, Cao X, Pokiak A, Gittelsohn J, Corriveau A.

Can J Public Health. 2009 Nov-Dec;100(6):442-8.


Manual method for liquid-based cytology: a demonstration using 1,000 gynecological cytologies collected directly to vial and prepared by a smear-slide technique.

Maksem JA, Finnemore M, Belsheim BL, Roose EB, Makkapati SR, Eatwell L, Weidmann J.

Diagn Cytopathol. 2001 Nov;25(5):334-8.


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