Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 166

1.

TDP-43 proteinopathy in Theiler's murine encephalomyelitis virus infection.

Masaki K, Sonobe Y, Ghadge G, Pytel P, Roos RP.

PLoS Pathog. 2019 Feb 11;15(2):e1007574. doi: 10.1371/journal.ppat.1007574. eCollection 2019 Feb.

2.

Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice.

Ghadge GD, Kay BK, Drigotas C, Roos RP.

Neurobiol Dis. 2019 Jan;121:131-137. doi: 10.1016/j.nbd.2018.08.021. Epub 2018 Aug 31.

PMID:
30176351
3.

Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress.

Sonobe Y, Ghadge G, Masaki K, Sendoel A, Fuchs E, Roos RP.

Neurobiol Dis. 2018 Aug;116:155-165. doi: 10.1016/j.nbd.2018.05.009. Epub 2018 May 22.

4.

Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS.

Riehm JJ, Wang L, Ghadge G, Teng M, Correa AM, Marks JD, Roos RP, Allen MJ.

Neurobiol Dis. 2018 Jul;115:115-126. doi: 10.1016/j.nbd.2018.03.014. Epub 2018 Apr 5.

5.

2017 Year in Review and Message from the Editors to Our Reviewers.

Pulst SM, Johnson NE, Pandolfo M, Roos RP, Vance JM.

Neurol Genet. 2018 Feb 16;4(1):e221. doi: 10.1212/NXG.0000000000000221. eCollection 2018 Feb. No abstract available.

6.

A Masked Marauder: Hepatitis C Neuropathy.

Rezania K, Pytel P, Derani L, Greenwald R, Roos RP.

Am J Med. 2018 Jan;131(1):33-36. doi: 10.1016/j.amjmed.2017.08.015. Epub 2017 Sep 4. No abstract available.

PMID:
28882660
7.

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics.

Mackenzie IR, Nicholson AM, Sarkar M, Messing J, Purice MD, Pottier C, Annu K, Baker M, Perkerson RB, Kurti A, Matchett BJ, Mittag T, Temirov J, Hsiung GR, Krieger C, Murray ME, Kato M, Fryer JD, Petrucelli L, Zinman L, Weintraub S, Mesulam M, Keith J, Zivkovic SA, Hirsch-Reinshagen V, Roos RP, Züchner S, Graff-Radford NR, Petersen RC, Caselli RJ, Wszolek ZK, Finger E, Lippa C, Lacomis D, Stewart H, Dickson DW, Kim HJ, Rogaeva E, Bigio E, Boylan KB, Taylor JP, Rademakers R.

Neuron. 2017 Aug 16;95(4):808-816.e9. doi: 10.1016/j.neuron.2017.07.025.

8.

Evidence for an early innate immune response in the motor cortex of ALS.

Jara JH, Genç B, Stanford MJ, Pytel P, Roos RP, Weintraub S, Mesulam MM, Bigio EH, Miller RJ, Özdinler PH.

J Neuroinflammation. 2017 Jun 26;14(1):129. doi: 10.1186/s12974-017-0896-4.

9.

2016 in Review and Message from the Editors to our Reviewers.

Pulst SM, Johnson NE, Durr A, Pandolfo M, Roos RP, Vance JM.

Neurol Genet. 2017 Feb 15;3(1):e132. doi: 10.1212/NXG.0000000000000132. eCollection 2017 Feb. No abstract available.

10.

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS.

Genç B, Jara JH, Lagrimas AK, Pytel P, Roos RP, Mesulam MM, Geula C, Bigio EH, Özdinler PH.

Sci Rep. 2017 Feb 6;7:41765. doi: 10.1038/srep41765.

11.

S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects.

Antinone SE, Ghadge GD, Ostrow LW, Roos RP, Green WN.

Sci Rep. 2017 Jan 25;7:41141. doi: 10.1038/srep41141.

12.

Gastrostomy tube placement is safe in advanced amyotrophic lateral sclerosis.

Kak M, Issa NP, Roos RP, Sweitzer BJ, Gottlieb O, Guralnick A, White SR, Semrad CE, Soliven B, Baroody J, Rezania K.

Neurol Res. 2017 Jan;39(1):16-22. Epub 2016 Nov 23.

PMID:
27876446
13.

Intermuscular coherence in amyotrophic lateral sclerosis: A preliminary assessment.

Issa NP, Frank S, Roos RP, Soliven B, Towle VL, Rezania K.

Muscle Nerve. 2017 Jun;55(6):862-868. doi: 10.1002/mus.25426. Epub 2017 Feb 3.

PMID:
27699797
14.

Zika Virus-A Public Health Emergency of International Concern.

Roos RP.

JAMA Neurol. 2016 Dec 1;73(12):1395-1396. doi: 10.1001/jamaneurol.2016.3677. No abstract available.

PMID:
27695847
15.

D. CARLETON GAJDUSEK.

Roos RP.

Proc Am Philos Soc. 2015 Mar;159(1):97-106. No abstract available.

PMID:
27011963
16.

Neoplastic cauda equina syndrome: a neuroimaging-based review.

Bennett SJ, Katzman GL, Roos RP, Mehta AS, Ali S.

Pract Neurol. 2016 Feb;16(1):35-41. doi: 10.1136/practneurol-2015-001236. Epub 2015 Oct 6. Review.

PMID:
26442520
17.

Animal extremists' threats to neurologic research continue: Neuroreality II.

Beversdorf DQ, Roos RP, Hauser WA, Lennon VA, Mehler MF.

Neurology. 2015 Aug 25;85(8):730-4. doi: 10.1212/WNL.0000000000001764. Epub 2015 Jul 8. Review. No abstract available.

18.

Corticospinal Motor Neurons Are Susceptible to Increased ER Stress and Display Profound Degeneration in the Absence of UCHL1 Function.

Jara JH, Genç B, Cox GA, Bohn MC, Roos RP, Macklis JD, Ulupınar E, Özdinler PH.

Cereb Cortex. 2015 Nov;25(11):4259-72. doi: 10.1093/cercor/bhu318. Epub 2015 Jan 16.

19.

Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.

Wang L, Popko B, Tixier E, Roos RP.

Neurobiol Dis. 2014 Nov;71:317-24. doi: 10.1016/j.nbd.2014.08.010. Epub 2014 Aug 15.

20.

Venous thromboembolism after diaphragm pacing in amyotrophic lateral sclerosis.

Rezania K, Gottlieb O, Guralnick A, Prachand V, Sweitzer BJ, Vigneswaran W, White SR, Roos RP.

Muscle Nerve. 2014 Nov;50(5):863-5. doi: 10.1002/mus.24420. Epub 2014 Sep 24.

PMID:
25111569
21.

An enhanced integrated stress response ameliorates mutant SOD1-induced ALS.

Wang L, Popko B, Roos RP.

Hum Mol Genet. 2014 May 15;23(10):2629-38. doi: 10.1093/hmg/ddt658. Epub 2013 Dec 23.

22.

Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants.

Antinone SE, Ghadge GD, Lam TT, Wang L, Roos RP, Green WN.

J Biol Chem. 2013 Jul 26;288(30):21606-17. doi: 10.1074/jbc.M113.487231. Epub 2013 Jun 12.

23.

Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1.

Ghadge GD, Pavlovic JD, Koduvayur SP, Kay BK, Roos RP.

Neurobiol Dis. 2013 Aug;56:74-8. doi: 10.1016/j.nbd.2013.04.007. Epub 2013 Apr 20. Erratum in: Neurobiol Dis. 2013 Oct;58:115.

24.

Spinal cord: motor neuron diseases.

Rezania K, Roos RP.

Neurol Clin. 2013 Feb;31(1):219-39. doi: 10.1016/j.ncl.2012.09.014. Review.

PMID:
23186902
25.

Selective knockdown of mutant SOD1 in Schwann cells ameliorates disease in G85R mutant SOD1 transgenic mice.

Wang L, Pytel P, Feltri ML, Wrabetz L, Roos RP.

Neurobiol Dis. 2012 Oct;48(1):52-7. doi: 10.1016/j.nbd.2012.05.014. Epub 2012 Jun 2. Erratum in: Neurobiol Dis. 2013 Jul;55:36.

PMID:
22668777
26.

Mutant SOD1 forms ion channel: implications for ALS pathophysiology.

Allen MJ, Lacroix JJ, Ramachandran S, Capone R, Whitlock JL, Ghadge GD, Arnsdorf MF, Roos RP, Lal R.

Neurobiol Dis. 2012 Mar;45(3):831-8. doi: 10.1016/j.nbd.2011.08.031. Epub 2011 Sep 10.

27.

The L-coding region of the DA strain of Theiler's murine encephalomyelitis virus causes dysfunction and death of myelin-synthesizing cells.

Ghadge GD, Wollmann R, Baida G, Traka M, Roos RP.

J Virol. 2011 Sep;85(18):9377-84. doi: 10.1128/JVI.00178-11. Epub 2011 Jul 13.

28.

Apoptotic and antiapoptotic activity of L protein of Theiler's murine encephalomyelitis virus.

Stavrou S, Ghadge G, Roos RP.

J Virol. 2011 Jul;85(14):7177-85. doi: 10.1128/JVI.00009-11. Epub 2011 May 11.

29.

Impaired glucose tolerance and metabolic syndrome in idiopathic polyneuropathy: the role of pain and depression.

Rezania K, Soliven B, Rezai KA, Roos RP.

Med Hypotheses. 2011 Apr;76(4):538-42. doi: 10.1016/j.mehy.2010.12.012. Epub 2011 Jan 20.

PMID:
21255940
30.

The unfolded protein response in familial amyotrophic lateral sclerosis.

Wang L, Popko B, Roos RP.

Hum Mol Genet. 2011 Mar 1;20(5):1008-15. doi: 10.1093/hmg/ddq546. Epub 2010 Dec 15.

31.

Astrocyte loss of mutant SOD1 delays ALS disease onset and progression in G85R transgenic mice.

Wang L, Gutmann DH, Roos RP.

Hum Mol Genet. 2011 Jan 15;20(2):286-93. doi: 10.1093/hmg/ddq463. Epub 2010 Oct 20.

PMID:
20962037
32.

Different strains of Theiler's murine encephalomyelitis virus antagonize different sites in the type I interferon pathway.

Stavrou S, Feng Z, Lemon SM, Roos RP.

J Virol. 2010 Sep;84(18):9181-9. doi: 10.1128/JVI.00603-10. Epub 2010 Jul 7.

33.

Mutant SOD1 knockdown in all cell types ameliorates disease in G85R SOD1 mice with a limited additional effect over knockdown restricted to motor neurons.

Wang L, Grisotti G, Roos RP.

J Neurochem. 2010 Apr;113(1):166-74. doi: 10.1111/j.1471-4159.2010.06594.x. Epub 2010 Feb 2.

34.

GCP II inhibition rescues neurons from gp120IIIB-induced neurotoxicity.

Thomas AG, Bodner A, Ghadge G, Roos RP, Slusher BS.

J Neurovirol. 2009 Sep;15(5-6):449-57. doi: 10.3109/13550280903350598.

PMID:
19995130
35.

Theiler's murine encephalomyelitis virus L* amino acid position 93 is important for virus persistence and virus-induced demyelination.

Stavrou S, Baida G, Viktorova E, Ghadge G, Agol VI, Roos RP.

J Virol. 2010 Feb;84(3):1348-54. doi: 10.1128/JVI.01585-09. Epub 2009 Nov 18.

36.

The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis.

Wang L, Sharma K, Grisotti G, Roos RP.

Neurobiol Dis. 2009 Aug;35(2):234-40. doi: 10.1016/j.nbd.2009.05.002. Epub 2009 May 12.

37.

Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.

Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP.

Hum Mol Genet. 2009 May 1;18(9):1642-51. doi: 10.1093/hmg/ddp085. Epub 2009 Feb 19.

38.

An elderly patient with Bickerstaff brainstem encephalitis and transient episodes of brainstem dysfunction.

Roos RP, Soliven B, Goldenberg F, Badruddin A, Baron JM.

Arch Neurol. 2008 Jun;65(6):821-4. doi: 10.1001/archneur.65.6.821.

PMID:
18541805
39.

A subgenomic segment of Theiler's murine encephalomyelitis virus RNA causes demyelination.

Baida G, Popko B, Wollmann RL, Stavrou S, Lin W, Tretiakova M, Krausz TN, Roos RP.

J Virol. 2008 Jun;82(12):5879-86. doi: 10.1128/JVI.02432-07. Epub 2008 Apr 9.

40.

Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology.

Wang L, Sharma K, Deng HX, Siddique T, Grisotti G, Liu E, Roos RP.

Neurobiol Dis. 2008 Mar;29(3):400-8. Epub 2007 Oct 23.

PMID:
18054242
41.

Truncated wild-type SOD1 and FALS-linked mutant SOD1 cause neural cell death in the chick embryo spinal cord.

Ghadge GD, Wang L, Sharma K, Monti AL, Bindokas V, Stevens FJ, Roos RP.

Neurobiol Dis. 2006 Jan;21(1):194-205. Epub 2005 Aug 9.

PMID:
16084730
42.

Molecular mechanisms of attenuation of the Sabin strain of poliovirus type 3.

Guest S, Pilipenko E, Sharma K, Chumakov K, Roos RP.

J Virol. 2004 Oct;78(20):11097-107.

43.

CD4+ T cells are important for clearance of DA strain of TMEV from the central nervous system of SJL/J mice.

Lin X, Ma X, Rodriguez M, Roos RP.

Int Immunol. 2004 Sep;16(9):1237-40. Epub 2004 Jul 19.

PMID:
15262897
44.

Failure to detect enterovirus in the spinal cord of ALS patients using a sensitive RT-PCR method.

Nix WA, Berger MM, Oberste MS, Brooks BR, McKenna-Yasek DM, Brown RH Jr, Roos RP, Pallansch MA.

Neurology. 2004 Apr 27;62(8):1372-7.

PMID:
15111676
45.

Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cells.

Mathiasen JR, McKenna BA, Saporito MS, Ghadge GD, Roos RP, Holskin BP, Wu ZL, Trusko SP, Connors TC, Maroney AC, Thomas BA, Thomas JC, Bozyczko-Coyne D.

Brain Res. 2004 Apr 2;1003(1-2):86-97.

PMID:
15019567
46.

Wrinkles and folds of the prion protein.

Mastrianni JA, Roos RP.

Neurology. 2003 Nov 11;61(9):1168-9. No abstract available.

PMID:
14610113
47.

A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy.

Rezania K, Yan J, Dellefave L, Deng HX, Siddique N, Pascuzzi RT, Siddique T, Roos RP.

Amyotroph Lateral Scler Other Motor Neuron Disord. 2003 Sep;4(3):162-6.

PMID:
13129803
48.

Membrane lymphotoxin is required for resistance to Theiler's virus infection.

Lin X, Ma X, Rodriguez M, Feng X, Zoecklein L, Fu YX, Roos RP.

Int Immunol. 2003 Aug;15(8):955-62.

PMID:
12882833
49.

Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models.

Ghadge GD, Slusher BS, Bodner A, Canto MD, Wozniak K, Thomas AG, Rojas C, Tsukamoto T, Majer P, Miller RJ, Monti AL, Roos RP.

Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9554-9. Epub 2003 Jul 22.

50.

No correlation between aggregates of Cu/Zn superoxide dismutase and cell death in familial amyotrophic lateral sclerosis.

Lee JP, Gerin C, Bindokas VP, Miller R, Ghadge G, Roos RP.

J Neurochem. 2002 Sep;82(5):1229-38.

Supplemental Content

Support Center