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Response: Or both?

Roos G, Rosenquist R, Stilgenbauer S.

Blood. 2008 Jun 15;111(12):5756-5757. doi: 10.1182/blood-2008-04-149401. No abstract available.


DNA methylation associates with survival in non-metastatic clear cell renal cell carcinoma.

Evelönn EA, Landfors M, Haider Z, Köhn L, Ljungberg B, Roos G, Degerman S.

BMC Cancer. 2019 Jan 14;19(1):65. doi: 10.1186/s12885-019-5291-3.


Molecular mechanism of substrate selectivity of the arginine-agmatine Antiporter AdiC.

Krammer EM, Gibbons A, Roos G, Prévost M.

Sci Rep. 2018 Oct 23;8(1):15607. doi: 10.1038/s41598-018-33963-1.


[A man with thoracic pain after visiting the tropics].

Elsinger F, Roos GKR, Sulzer MA.

Ned Tijdschr Geneeskd. 2018 Aug 30;162. pii: D2700. Dutch.


How Biochemical Environments Fine-Tune a Redox Process: From Theoretical Models to Practical Applications.

Roos G, Miranda-Quintana RA, Martínez González M.

J Phys Chem B. 2018 Aug 30;122(34):8157-8165. doi: 10.1021/acs.jpcb.8b04736. Epub 2018 Aug 17.


Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation-The Example of FimH.

Krammer EM, de Ruyck J, Roos G, Bouckaert J, Lensink MF.

Molecules. 2018 Jul 5;23(7). pii: E1641. doi: 10.3390/molecules23071641. Review.


How Mg2+ ions lower the SN2@P barrier in enzymatic triphosphate hydrolysis.

van Bochove MA, Roos G, Fonseca Guerra C, Hamlin TA, Bickelhaupt FM.

Chem Commun (Camb). 2018 Apr 3;54(28):3448-3451. doi: 10.1039/c8cc00700d.


Novel variants in Nordic patients referred for genetic testing of telomere-related disorders.

Norberg A, Rosén A, Raaschou-Jensen K, Kjeldsen L, Moilanen JS, Paulsson-Karlsson Y, Baliakas P, Lohi O, Ahmed A, Kittang AO, Larsson P, Roos G, Degerman S, Hultdin M.

Eur J Hum Genet. 2018 Jun;26(6):858-867. doi: 10.1038/s41431-018-0112-8. Epub 2018 Feb 26.


Views of policy makers and health promotion professionals on factors facilitating implementation and maintenance of interventions and policies promoting physical activity and healthy eating: results of the DEDIPAC project.

Muellmann S, Steenbock B, De Cocker K, De Craemer M, Hayes C, O'Shea MP, Horodyska K, Bell J, Luszczynska A, Roos G, Langøien LJ, Rugseth G, Terragni L, De Bourdeaudhuij I, Brug J, Pischke CR.

BMC Public Health. 2017 Dec 6;17(1):932. doi: 10.1186/s12889-017-4929-9.


Developing a systems-based framework of the factors influencing dietary and physical activity behaviours in ethnic minority populations living in Europe - a DEDIPAC study.

Holdsworth M, Nicolaou M, Langøien LJ, Osei-Kwasi HA, Chastin SFM, Stok FM, Capranica L, Lien N, Terragni L, Monsivais P, Mazzocchi M, Maes L, Roos G, Mejean C, Powell K, Stronks K.

Int J Behav Nutr Phys Act. 2017 Nov 7;14(1):154. doi: 10.1186/s12966-017-0608-6.


Determinants of diet and physical activity (DEDIPAC): a summary of findings.

Brug J, van der Ploeg HP, Loyen A, Ahrens W, Allais O, Andersen LF, Cardon G, Capranica L, Chastin S, De Bourdeaudhuij I, De Craemer M, Donnelly A, Ekelund U, Finglas P, Flechtner-Mors M, Hebestreit A, Kubiak T, Lanza M, Lien N, MacDonncha C, Mazzocchi M, Monsivais P, Murphy M, Nicolaou M, Nöthlings U, O'Gorman DJ, Renner B, Roos G, van den Berg M, Schulze MB, Steinacker JM, Stronks K, Volkert D, Lakerveld J; DEDIPAC consortium.

Int J Behav Nutr Phys Act. 2017 Nov 3;14(1):150. doi: 10.1186/s12966-017-0609-5.


Systematic mapping review of the factors influencing physical activity and sedentary behaviour in ethnic minority groups in Europe: a DEDIPAC study.

Langøien LJ, Terragni L, Rugseth G, Nicolaou M, Holdsworth M, Stronks K, Lien N, Roos G; DEDIPAC consortium.

Int J Behav Nutr Phys Act. 2017 Jul 24;14(1):99. doi: 10.1186/s12966-017-0554-3. Review.


Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.

Rabbani S, Krammer EM, Roos G, Zalewski A, Preston R, Eid S, Zihlmann P, Prévost M, Lensink MF, Thompson A, Ernst B, Bouckaert J.

IUCrJ. 2017 Jan 1;4(Pt 1):7-23. doi: 10.1107/S2052252516016675. eCollection 2017 Jan 1.


Long leukocyte telomere length in prostate cancer patients at diagnosis is associated with poor metastasis-free and cancer-specific survival.

Svenson U, Roos G, Wikström P.

Tumour Biol. 2017 Feb;39(2):1010428317692236. doi: 10.1177/1010428317692236.


Decreased telomere length in children with cartilage-hair hypoplasia.

Kostjukovits S, Degerman S, Pekkinen M, Klemetti P, Landfors M, Roos G, Taskinen M, Mäkitie O.

J Med Genet. 2017 May;54(5):365-370. doi: 10.1136/jmedgenet-2016-104279. Epub 2016 Dec 16.


Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study.

Aldib I, Gelbcke M, Soubhye J, Prévost M, Furtmüller PG, Obinger C, Elfving B, Alard IC, Roos G, Delporte C, Berger G, Dufour D, Zouaoui Boudjeltia K, Nève J, Dufrasne F, Van Antwerpen P.

Eur J Med Chem. 2016 Nov 10;123:746-762. doi: 10.1016/j.ejmech.2016.07.053. Epub 2016 Jul 25.


Influencing factors of children's fruit, vegetable and sugar-enriched food intake in a Finnish preschool setting - Preschool personnel's perceptions.

Ray C, Määttä S, Lehto R, Roos G, Roos E.

Appetite. 2016 Aug 1;103:72-79. doi: 10.1016/j.appet.2016.03.020. Epub 2016 Mar 25.


Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes.

Machiela MJ, Lan Q, Slager SL, Vermeulen RC, Teras LR, Camp NJ, Cerhan JR, Spinelli JJ, Wang SS, Nieters A, Vijai J, Yeager M, Wang Z, Ghesquières H, McKay J, Conde L, de Bakker PI, Cox DG, Burdett L, Monnereau A, Flowers CR, De Roos AJ, Brooks-Wilson AR, Giles GG, Melbye M, Gu J, Jackson RD, Kane E, Purdue MP, Vajdic CM, Albanes D, Kelly RS, Zucca M, Bertrand KA, Zeleniuch-Jacquotte A, Lawrence C, Hutchinson A, Zhi D, Habermann TM, Link BK, Novak AJ, Dogan A, Asmann YW, Liebow M, Thompson CA, Ansell SM, Witzig TE, Tilly H, Haioun C, Molina TJ, Hjalgrim H, Glimelius B, Adami HO, Roos G, Bracci PM, Riby J, Smith MT, Holly EA, Cozen W, Hartge P, Morton LM, Severson RK, Tinker LF, North KE, Becker N, Benavente Y, Boffetta P, Brennan P, Foretova L, Maynadie M, Staines A, Lightfoot T, Crouch S, Smith A, Roman E, Diver WR, Offit K, Zelenetz A, Klein RJ, Villano DJ, Zheng T, Zhang Y, Holford TR, Turner J, Southey MC, Clavel J, Virtamo J, Weinstein S, Riboli E, Vineis P, Kaaks R, Boeing H, Tjønneland A, Angelucci E, Di Lollo S, Rais M, De Vivo I, Giovannucci E, Kraft P, Huang J, Ma B, Ye Y, Chiu BC, Liang L, Park JH, Chung CC, Weisenburger DD, Fraumeni JF Jr, Salles G, Glenn M, Cannon-Albright L, Curtin K, Wu X, Smedby KE, de Sanjose S, Skibola CF, Berndt SI, Birmann BM, Chanock SJ, Rothman N.

Hum Mol Genet. 2016 Apr 15;25(8):1663-76. doi: 10.1093/hmg/ddw027. Epub 2016 Feb 9.


The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut.

Alvarez Dorta D, Sivignon A, Chalopin T, Dumych TI, Roos G, Bilyy RO, Deniaud D, Krammer EM, de Ruyck J, Lensink MF, Bouckaert J, Barnich N, Gouin SG.

Chembiochem. 2016 May 17;17(10):936-52. doi: 10.1002/cbic.201600018. Epub 2016 Apr 8.


DNA Methylation Adds Prognostic Value to Minimal Residual Disease Status in Pediatric T-Cell Acute Lymphoblastic Leukemia.

Borssén M, Haider Z, Landfors M, Norén-Nyström U, Schmiegelow K, Åsberg AE, Kanerva J, Madsen HO, Marquart H, Heyman M, Hultdin M, Roos G, Forestier E, Degerman S.

Pediatr Blood Cancer. 2016 Jul;63(7):1185-92. doi: 10.1002/pbc.25958. Epub 2016 Feb 29.


Telomere length in peripheral leukocytes is associated with immune cell tumor infiltration and prognosis in colorectal cancer patients.

Svenson U, Öberg Å, Stenling R, Palmqvist R, Roos G.

Tumour Biol. 2016 Aug;37(8):10877-82. doi: 10.1007/s13277-016-4987-0. Epub 2016 Feb 16.


DNA methylation status defines clinicopathological parameters including survival for patients with clear cell renal cell carcinoma (ccRCC).

Evelönn EA, Degerman S, Köhn L, Landfors M, Ljungberg B, Roos G.

Tumour Biol. 2016 Aug;37(8):10219-28. doi: 10.1007/s13277-016-4893-5. Epub 2016 Jan 30.


Implementation conditions for diet and physical activity interventions and policies: an umbrella review.

Horodyska K, Luszczynska A, Hayes CB, O'Shea MP, Langøien LJ, Roos G, van den Berg M, Hendriksen M, De Bourdeaudhuij I, Brug J.

BMC Public Health. 2015 Dec 17;15:1250. doi: 10.1186/s12889-015-2585-5. Review.


Is Southern blotting necessary to measure telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements.

Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, Van Der Harst P, Bekaert S, De Meyer T, Roos G, Svenson U, Codd V, Samani NJ, Mcglynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, Von Zglinicki T.

Int J Epidemiol. 2015 Oct;44(5):1686-7. doi: 10.1093/ije/dyv169. Epub 2015 Sep 24. No abstract available.


Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic.

Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, Van Der Harst P, Bekaert S, De Meyer T, Roos G, Svenson U, Codd V, Samani NJ, Mcglynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, Von Zglinicki T.

Int J Epidemiol. 2015 Oct;44(5):1739-41. doi: 10.1093/ije/dyv170. Epub 2015 Sep 24. No abstract available.


Reproducibility of Telomere Length Assessment--An International Collaborative Study.

Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, van der Harst P, Bekaert S, de Meyer T, Roos G, Svenson U, Codd V, Samani NJ, McGlynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, von Zglinicki T.

Int J Epidemiol. 2015 Oct;44(5):1749-54. doi: 10.1093/ije/dyv171. Epub 2015 Sep 24. No abstract available.


Organic Food Consumption during Pregnancy and Hypospadias and Cryptorchidism at Birth: The Norwegian Mother and Child Cohort Study (MoBa).

Brantsæter AL, Torjusen H, Meltzer HM, Papadopoulou E, Hoppin JA, Alexander J, Lieblein G, Roos G, Holten JM, Swartz J, Haugen M.

Environ Health Perspect. 2016 Mar;124(3):357-64. doi: 10.1289/ehp.1409518. Epub 2015 Jul 9.


Convergence of atomic charges with the size of the enzymatic environment.

Vanpoucke DE, Oláh J, De Proft F, Van Speybroeck V, Roos G.

J Chem Inf Model. 2015 Mar 23;55(3):564-71. doi: 10.1021/ci5006417. Epub 2015 Feb 24.


Good practice characteristics of diet and physical activity interventions and policies: an umbrella review.

Horodyska K, Luszczynska A, van den Berg M, Hendriksen M, Roos G, De Bourdeaudhuij I, Brug J.

BMC Public Health. 2015 Jan 21;15:19. doi: 10.1186/s12889-015-1354-9. Review.


Long leukocyte telomere length at diagnosis is a risk factor for dementia progression in idiopathic parkinsonism.

Degerman S, Domellöf M, Landfors M, Linder J, Lundin M, Haraldsson S, Elgh E, Roos G, Forsgren L.

PLoS One. 2014 Dec 12;9(12):e113387. doi: 10.1371/journal.pone.0113387. eCollection 2014.


TERT promoter mutations in clear cell renal cell carcinoma.

Hosen I, Rachakonda PS, Heidenreich B, Sitaram RT, Ljungberg B, Roos G, Hemminki K, Kumar R.

Int J Cancer. 2015 May 15;136(10):2448-52. doi: 10.1002/ijc.29279. Epub 2014 Oct 30.


Reproducibility of telomere length assessment: an international collaborative study.

Martin-Ruiz CM, Baird D, Roger L, Boukamp P, Krunic D, Cawthon R, Dokter MM, van der Harst P, Bekaert S, de Meyer T, Roos G, Svenson U, Codd V, Samani NJ, McGlynn L, Shiels PG, Pooley KA, Dunning AM, Cooper R, Wong A, Kingston A, von Zglinicki T.

Int J Epidemiol. 2015 Oct;44(5):1673-83. doi: 10.1093/ije/dyu191. Epub 2014 Sep 19.


A case of disseminated histoplasmosis diagnosed after oral presentation in an old HIV-negative patient in Sweden.

Mota de Almeida FJ, Kivijärvi K, Roos G, Nylander K.

Gerodontology. 2015 Sep;32(3):234-6. doi: 10.1111/ger.12150. Epub 2014 Sep 10.


Reduced risk of pre-eclampsia with organic vegetable consumption: results from the prospective Norwegian Mother and Child Cohort Study.

Torjusen H, Brantsæter AL, Haugen M, Alexander J, Bakketeig LS, Lieblein G, Stigum H, Næs T, Swartz J, Holmboe-Ottesen G, Roos G, Meltzer HM.

BMJ Open. 2014 Sep 10;4(9):e006143. doi: 10.1136/bmjopen-2014-006143.


Stand up for health--avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people.

Sjögren P, Fisher R, Kallings L, Svenson U, Roos G, Hellénius ML.

Br J Sports Med. 2014 Oct;48(19):1407-9. doi: 10.1136/bjsports-2013-093342. Epub 2014 Sep 3.


Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias.

Degerman S, Landfors M, Siwicki JK, Revie J, Borssén M, Evelönn E, Forestier E, Chrzanowska KH, Rydén P, Keith WN, Roos G.

Neoplasia. 2014 Jul;16(7):606-15. doi: 10.1016/j.neo.2014.07.001. Epub 2014 Jul 22.


From thiol to sulfonic acid: modeling the oxidation pathway of protein thiols by hydrogen peroxide.

van Bergen LA, Roos G, De Proft F.

J Phys Chem A. 2014 Aug 7;118(31):6078-84. doi: 10.1021/jp5018339. Epub 2014 Jul 29.


Specific genomic aberrations predict survival, but low mutation rate in cancer hot spots, in clear cell renal cell carcinoma.

Köhn L, Svenson U, Ljungberg B, Roos G.

Appl Immunohistochem Mol Morphol. 2015 May-Jun;23(5):334-42. doi: 10.1097/PAI.0000000000000087.


A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.

Ueda Y, Calado RT, Norberg A, Kajigaya S, Roos G, Hellstrom-Lindberg E, Young NS.

BMC Med Genet. 2014 Jun 19;15:68. doi: 10.1186/1471-2350-15-68.


Validation of Reactivity Descriptors to Assess the Aromatic Stacking within the Tyrosine Gate of FimH.

Roos G, Wellens A, Touaibia M, Yamakawa N, Geerlings P, Roy R, Wyns L, Bouckaert J.

ACS Med Chem Lett. 2013 Sep 13;4(11):1085-90. doi: 10.1021/ml400269v. eCollection 2013 Nov 14.


How does the protein environment optimize the thermodynamics of thiol sulfenylation? Insights from model systems to QM/MM calculations on human 2-Cys peroxiredoxin.

Oláh J, van Bergen L, De Proft F, Roos G.

J Biomol Struct Dyn. 2015;33(3):584-96. doi: 10.1080/07391102.2014.907543. Epub 2014 Apr 24.


Towards the integration and development of a cross-European research network and infrastructure: the DEterminants of DIet and Physical ACtivity (DEDIPAC) Knowledge Hub.

Lakerveld J, van der Ploeg HP, Kroeze W, Ahrens W, Allais O, Andersen LF, Cardon G, Capranica L, Chastin S, Donnelly A, Ekelund U, Finglas P, Flechtner-Mors M, Hebestreit A, Hendriksen I, Kubiak T, Lanza M, Loyen A, MacDonncha C, Mazzocchi M, Monsivais P, Murphy M, Nöthlings U, O'Gorman DJ, Renner B, Roos G, Schuit AJ, Schulze M, Steinacker J, Stronks K, Volkert D, Van't Veer P, Lien N, De Bourdeaudhuij I, Brug J; DEDIPAC consortium.

Int J Behav Nutr Phys Act. 2014 Nov 22;11:143. doi: 10.1186/s12966-014-0143-7.


Gender and telomere length: systematic review and meta-analysis.

Gardner M, Bann D, Wiley L, Cooper R, Hardy R, Nitsch D, Martin-Ruiz C, Shiels P, Sayer AA, Barbieri M, Bekaert S, Bischoff C, Brooks-Wilson A, Chen W, Cooper C, Christensen K, De Meyer T, Deary I, Der G, Diez Roux A, Fitzpatrick A, Hajat A, Halaschek-Wiener J, Harris S, Hunt SC, Jagger C, Jeon HS, Kaplan R, Kimura M, Lansdorp P, Li C, Maeda T, Mangino M, Nawrot TS, Nilsson P, Nordfjall K, Paolisso G, Ren F, Riabowol K, Robertson T, Roos G, Staessen JA, Spector T, Tang N, Unryn B, van der Harst P, Woo J, Xing C, Yadegarfar ME, Park JY, Young N, Kuh D, von Zglinicki T, Ben-Shlomo Y; Halcyon study team.

Exp Gerontol. 2014 Mar;51:15-27. doi: 10.1016/j.exger.2013.12.004. Epub 2013 Dec 21. Review.


A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.

Speedy HE, Di Bernardo MC, Sava GP, Dyer MJ, Holroyd A, Wang Y, Sunter NJ, Mansouri L, Juliusson G, Smedby KE, Roos G, Jayne S, Majid A, Dearden C, Hall AG, Mainou-Fowler T, Jackson GH, Summerfield G, Harris RJ, Pettitt AR, Allsup DJ, Bailey JR, Pratt G, Pepper C, Fegan C, Rosenquist R, Catovsky D, Allan JM, Houlston RS.

Nat Genet. 2014 Jan;46(1):56-60. doi: 10.1038/ng.2843. Epub 2013 Dec 1.


How the disulfide conformation determines the disulfide/thiol redox potential.

Roos G, Fonseca Guerra C, Bickelhaupt FM.

J Biomol Struct Dyn. 2015;33(1):93-103. doi: 10.1080/07391102.2013.851034. Epub 2013 Nov 21.


Shorter telomere length is linked to brain atrophy and white matter hyperintensities.

Wikgren M, Karlsson T, Söderlund H, Nordin A, Roos G, Nilsson LG, Adolfsson R, Norrback KF.

Age Ageing. 2014 Mar;43(2):212-7. doi: 10.1093/ageing/aft172. Epub 2013 Nov 14.


TGF-βRI kinase activity mediates Emdogain-stimulated in vitro osteoclastogenesis.

Gruber R, Roos G, Caballé-Serrano J, Miron R, Bosshardt DD, Sculean A.

Clin Oral Investig. 2014 Jul;18(6):1639-46. doi: 10.1007/s00784-013-1129-6. Epub 2013 Nov 13.


Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn's disease patients.

Brument S, Sivignon A, Dumych TI, Moreau N, Roos G, Guérardel Y, Chalopin T, Deniaud D, Bilyy RO, Darfeuille-Michaud A, Bouckaert J, Gouin SG.

J Med Chem. 2013 Jul 11;56(13):5395-406. doi: 10.1021/jm400723n. Epub 2013 Jun 24.


Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia.

Borssén M, Palmqvist L, Karrman K, Abrahamsson J, Behrendtz M, Heldrup J, Forestier E, Roos G, Degerman S.

PLoS One. 2013 Jun 6;8(6):e65373. doi: 10.1371/journal.pone.0065373. Print 2013.


Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients.

Mansouri L, Grabowski P, Degerman S, Svenson U, Gunnarsson R, Cahill N, Smedby KE, Geisler C, Juliusson G, Roos G, Rosenquist R.

Am J Hematol. 2013 Aug;88(8):647-51. doi: 10.1002/ajh.23466. Epub 2013 Jun 20.

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