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Future prospects for dissecting inter-individual variability in the absorption, distribution and elimination of plant bioactives of relevance for cardiometabolic endpoints.

Landberg R, Manach C, Kerckhof FM, Minihane AM, Saleh RNM, De Roos B, Tomas-Barberan F, Morand C, Van de Wiele T.

Eur J Nutr. 2019 Nov;58(Suppl 2):21-36. doi: 10.1007/s00394-019-02095-1. Epub 2019 Oct 23. Review.


Targeting the delivery of dietary plant bioactives to those who would benefit most: from science to practical applications.

de Roos B, Aura AM, Bronze M, Cassidy A, Conesa MG, Gibney ER, Greyling A, Kaput J, Kerem Z, Knežević N, Kroon P, Landberg R, Manach C, Milenkovic D, Rodriguez-Mateos A, Tomás-Barberán FA, van de Wiele T, Morand C.

Eur J Nutr. 2019 Nov;58(Suppl 2):65-73. doi: 10.1007/s00394-019-02075-5. Epub 2019 Oct 22. Review.


Factors influencing the cardiometabolic response to (poly)phenols and phytosterols: a review of the COST Action POSITIVe activities.

Gibney ER, Milenkovic D, Combet E, Ruskovska T, Greyling A, González-Sarrías A, de Roos B, Tomás-Barberán F, Morand C, Rodriguez-Mateos A.

Eur J Nutr. 2019 Nov;58(Suppl 2):37-47. doi: 10.1007/s00394-019-02066-6. Epub 2019 Sep 6. Review.


Linking agroecosystems producing farmed seafood with food security and health status to better address the nutritional challenges in Bangladesh.

de Roos B, Roos N, Mamun AA, Ahmed T, Sneddon AA, Murray F, Grieve E, Little DC.

Public Health Nutr. 2019 Nov;22(16):2941-2949. doi: 10.1017/S1368980019002295. Epub 2019 Sep 5.


Moderate hyperoxia induces senescence in developing human lung fibroblasts.

You K, Parikh P, Khandalavala K, Wicher SA, Manlove L, Yang B, Roesler A, Roos BB, Teske JJ, Britt RD Jr, Pabelick CM, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L525-L536. doi: 10.1152/ajplung.00067.2019. Epub 2019 Aug 14.


Myocilin Mutations in Patients With Normal-Tension Glaucoma.

Alward WLM, van der Heide C, Khanna CL, Roos BR, Sivaprasad S, Kam J, Ritch R, Lotery A, Igo RP Jr, Cooke Bailey JN, Stone EM, Scheetz TE, Kwon YH, Pasquale LR, Wiggs JL, Fingert JH; NEIGHBORHOOD Consortium.

JAMA Ophthalmol. 2019 May 1;137(5):559-563. doi: 10.1001/jamaophthalmol.2019.0005.


Effect of nonmeat, high-protein supplementation on quality of life and clinical outcomes in older residents of care homes: a systematic review and meta-analysis.

Donaldson AIC, Smith TO, Alder S, Johnstone AM, De Roos B, Aucott LS, Gordon AL, Myint PK.

Nutr Rev. 2019 Feb 1;77(2):116-127. doi: 10.1093/nutrit/nuy061.


SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice.

Sergi D, Campbell FM, Grant C, Morris AC, Bachmair EM, Koch C, McLean FH, Muller A, Hoggard N, de Roos B, Porteiro B, Boekschoten MV, McGillicuddy FC, Kahn D, Nicol P, Benzler J, Mayer CD, Drew JE, Roche HM, Muller M, Nogueiras R, Dieguez C, Tups A, Williams LM.

Genes Nutr. 2018 Nov 29;13:28. doi: 10.1186/s12263-018-0619-1. eCollection 2018.


Selenium and sulphur derivatives of hydroxytyrosol: inhibition of lipid peroxidation in liver microsomes of vitamin E-deficient rats.

Rodríguez-Gutiérrez G, Rubio-Senent F, Gómez-Carretero A, Maya I, Fernández-Bolaños J, Duthie GG, de Roos B.

Eur J Nutr. 2019 Aug;58(5):1847-1851. doi: 10.1007/s00394-018-1733-y. Epub 2018 May 28.


First-Pass CYP3A-Mediated Metabolism of Midazolam in the Gut Wall and Liver in Preterm Neonates.

Brussee JM, Yu H, Krekels EHJ, de Roos B, Brill MJE, van den Anker JN, Rostami-Hodjegan A, de Wildt SN, Knibbe CAJ.

CPT Pharmacometrics Syst Pharmacol. 2018 Jun;7(6):374-383. doi: 10.1002/psp4.12295. Epub 2018 May 10.


A novel mutation (LEU396ARG) in OPA1 is associated with a severe phenotype in a large dominant optic atrophy pedigree.

Schnieders MJ, Goar W, Griess M, Roos BR, Scheetz TE, Stone EM, Fingert JH.

Eye (Lond). 2018 Apr;32(4):843-845. doi: 10.1038/eye.2017.303. Epub 2018 Jan 19. No abstract available.


Open versus arthroscopic approach in the treatment of femoroacetabular impingement: a case-control study with two-years follow up.

Roos BD, Roos MV, Camisa Júnior A, Lima EMU, Betto MD.

Rev Bras Ortop. 2017 Aug 9;52(Suppl 1):21-28. doi: 10.1016/j.rboe.2017.07.007. eCollection 2017.


Personalised Interventions-A Precision Approach for the Next Generation of Dietary Intervention Studies.

de Roos B, Brennan L.

Nutrients. 2017 Aug 9;9(8). pii: E847. doi: 10.3390/nu9080847. Review.


Acute Consumption of Flavan-3-ol-Enriched Dark Chocolate Affects Human Endogenous Metabolism.

Ostertag LM, Philo M, Colquhoun IJ, Tapp HS, Saha S, Duthie GG, Kemsley EK, de Roos B, Kroon PA, Le Gall G.

J Proteome Res. 2017 Jul 7;16(7):2516-2526. doi: 10.1021/acs.jproteome.7b00089. Epub 2017 Jun 15.


The potential impact of compositional changes in farmed fish on its health-giving properties: is it time to reconsider current dietary recommendations?

de Roos B, Sneddon AA, Sprague M, Horgan GW, Brouwer IA.

Public Health Nutr. 2017 Aug;20(11):2042-2049. doi: 10.1017/S1368980017000696. Epub 2017 May 24.


LADD syndrome with glaucoma is caused by a novel gene.

Simpson A, Avdic A, Roos BR, DeLuca A, Miller K, Schnieders MJ, Scheetz TE, Alward WL, Fingert JH.

Mol Vis. 2017 Mar 30;23:179-184. eCollection 2017.


Assessment of a three-generation pedigree with Fuchs endothelial corneal dystrophy with anticipation for expansion of the triplet repeat in the TCF4 gene.

Greiner MA, Terveen DC, Vislisel JM, Roos BR, Fingert JH.

Eye (Lond). 2017 Aug;31(8):1250-1252. doi: 10.1038/eye.2017.60. Epub 2017 Apr 7. No abstract available.


The colonic metabolites dihydrocaffeic acid and dihydroferulic acid are more effective inhibitors of in vitro platelet activation than their phenolic precursors.

Baeza G, Bachmair EM, Wood S, Mateos R, Bravo L, de Roos B.

Food Funct. 2017 Mar 22;8(3):1333-1342. doi: 10.1039/c6fo01404f.


Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis.

Berends LM, Struys EA, Roos B, Holwerda U, Jansen EEW, Salomons GS, Wamelink MMC.

JIMD Rep. 2017;37:13-17. doi: 10.1007/8904_2017_4. Epub 2017 Feb 21.


Arthroscopic subcapital realignment osteotomy in chronic and stable slipped capital femoral epiphysis: early results.

Roos BD, Assis MC, Roos MV, Camisa Júnior A, Lima EM, Pagani RC.

Rev Bras Ortop. 2016 Dec 29;52(1):87-94. doi: 10.1016/j.rboe.2016.12.007. eCollection 2017 Jan-Feb.


Transgenic TBK1 mice have features of normal tension glaucoma.

Fingert JH, Miller K, Hedberg-Buenz A, Roos BR, Lewis CJ, Mullins RF, Anderson MG.

Hum Mol Genet. 2017 Jan 1;26(1):124-132. doi: 10.1093/hmg/ddw372.


An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high-fat "Western-type" diet in mice.

Jurado-Ruiz E, Varela LM, Luque A, Berná G, Cahuana G, Martinez-Force E, Gallego-Durán R, Soria B, de Roos B, Romero Gómez M, Martín F.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600549. Epub 2016 Dec 13.


Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.

Scheetz TE, Faga B, Ortega L, Roos BR, Gordon MO, Kass MA, Wang K, Fingert JH.

Ophthalmology. 2016 Dec;123(12):2527-2536. doi: 10.1016/j.ophtha.2016.08.036. Epub 2016 Oct 1.


Differences in expenditure and amounts of fresh foods, fruits and vegetables, and fish purchased in urban and rural Scotland.

de Roos B, Binacchi F, Whybrow S, Sneddon AA.

Public Health Nutr. 2017 Feb;20(3):524-533. doi: 10.1017/S1368980016002688. Epub 2016 Oct 5.


Addressing the inter-individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction.

Manach C, Milenkovic D, Van de Wiele T, Rodriguez-Mateos A, de Roos B, Garcia-Conesa MT, Landberg R, Gibney ER, Heinonen M, Tomás-Barberán F, Morand C.

Mol Nutr Food Res. 2017 Jun;61(6). doi: 10.1002/mnfr.201600557. Epub 2016 Nov 15. Review.


Availability and dose response of phytophenols from a wheat bran rich cereal product in healthy human volunteers.

Neacsu M, McMonagle J, Fletcher RJ, Hulshof T, Duncan SH, Scobbie L, Duncan GJ, Cantlay L, Horgan G, de Roos B, Duthie GG, Russell WR.

Mol Nutr Food Res. 2017 Mar;61(3). doi: 10.1002/mnfr.201600202. Epub 2017 Jan 25.


Clinical and genetic characterization of a large primary open angle glaucoma pedigree.

Kader MA, Namburi P, Ramugade S, Ramakrishnan R, Krishnadas SR, Roos BR, Periasamy S, Robin AL, Fingert JH.

Ophthalmic Genet. 2017 May-Jun;38(3):222-225. doi: 10.1080/13816810.2016.1193883. Epub 2016 Jun 29.


SQSTM1 Mutations and Glaucoma.

Scheetz TE, Roos BR, Solivan-Timpe F, Miller K, DeLuca AP, Stone EM, Kwon YH, Alward WL, Wang K, Fingert JH.

PLoS One. 2016 Jun 8;11(6):e0156001. doi: 10.1371/journal.pone.0156001. eCollection 2016.


Mutations in TKT Are the Cause of a Syndrome Including Short Stature, Developmental Delay, and Congenital Heart Defects.

Boyle L, Wamelink MMC, Salomons GS, Roos B, Pop A, Dauber A, Hwa V, Andrew M, Douglas J, Feingold M, Kramer N, Saitta S, Retterer K, Cho MT, Begtrup A, Monaghan KG, Wynn J, Chung WK.

Am J Hum Genet. 2016 Jun 2;98(6):1235-1242. doi: 10.1016/j.ajhg.2016.03.030.


Is life longer with a box of chocolates?

Donaldson AI, de Roos B, Johnstone AM, Myint PK.

Heart. 2016 Jul 1;102(13):990-1. doi: 10.1136/heartjnl-2016-309468. Epub 2016 Apr 11. No abstract available.


Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle.

Arrabal S, Lucena MA, Canduela MJ, Ramos-Uriarte A, Rivera P, Serrano A, Pavón FJ, Decara J, Vargas A, Baixeras E, Martín-Rufián M, Márquez J, Fernández-Llébrez P, De Roos B, Grandes P, Rodríguez de Fonseca F, Suárez J.

PLoS One. 2015 Dec 15;10(12):e0145244. doi: 10.1371/journal.pone.0145244. eCollection 2015.


Extracapsular approach for arthroscopic treatment of femoroacetabular impingement: clinical and radiographic results and complications.

Roos BD, Roos MV, Júnior AC, Lima EM, Gyboski DP, Martins LS.

Rev Bras Ortop. 2015 Jul 3;50(4):430-7. doi: 10.1016/j.rboe.2015.06.011. eCollection 2015 Jul-Aug.


Novel TMEM98 mutations in pedigrees with autosomal dominant nanophthalmos.

Khorram D, Choi M, Roos BR, Stone EM, Kopel T, Allen R, Alward WL, Scheetz TE, Fingert JH.

Mol Vis. 2015 Sep 1;21:1017-23. eCollection 2015.


Supplementation with a 9c,11t-rich conjugated linoleic acid blend shows no clear inhibitory effects on platelet function in healthy subjects at low and moderate cardiovascular risk: a randomized controlled trial.

Bachmair EM, Wood SG, Keizer HG, Horgan GW, Ford I, de Roos B.

Mol Nutr Food Res. 2015 Apr;59(4):741-50. doi: 10.1002/mnfr.201400495. Epub 2015 Feb 23.


Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly.

Hazlewood RJ, Roos BR, Solivan-Timpe F, Honkanen RA, Jampol LM, Gieser SC, Meyer KJ, Mullins RF, Kuehn MH, Scheetz TE, Kwon YH, Alward WL, Stone EM, Fingert JH.

Hum Mutat. 2015 Mar;36(3):369-78. doi: 10.1002/humu.22754.


Role of dietary pro-oxidants in the maintenance of health and resilience to oxidative stress.

de Roos B, Duthie GG.

Mol Nutr Food Res. 2015 Jul;59(7):1229-48. doi: 10.1002/mnfr.201400568. Epub 2015 Jan 22. Review.


Inhibitory and synergistic effects of natural olive phenols on human platelet aggregation and lipid peroxidation of microsomes from vitamin E-deficient rats.

Rubio-Senent F, de Roos B, Duthie G, Fernández-Bolaños J, Rodríguez-Gutiérrez G.

Eur J Nutr. 2015 Dec;54(8):1287-95. doi: 10.1007/s00394-014-0807-8. Epub 2014 Dec 14.


Copy number variations of TBK1 in Australian patients with primary open-angle glaucoma.

Awadalla MS, Fingert JH, Roos BE, Chen S, Holmes R, Graham SL, Chehade M, Galanopolous A, Ridge B, Souzeau E, Zhou T, Siggs OM, Hewitt AW, Mackey DA, Burdon KP, Craig JE.

Am J Ophthalmol. 2015 Jan;159(1):124-30.e1. doi: 10.1016/j.ajo.2014.09.044. Epub 2014 Oct 2.


Transcriptome analysis of peripheral blood mononuclear cells in human subjects following a 36 h fast provides evidence of effects on genes regulating inflammation, apoptosis and energy metabolism.

Elliott RM, de Roos B, Duthie SJ, Bouwman FG, Rubio-Aliaga I, Crosley LK, Mayer C, Polley AC, Heim C, Coort SL, Evelo CT, Mulholland F, Daniel H, Mariman EC, Johnson IT.

Genes Nutr. 2014 Nov;9(6):432. doi: 10.1007/s12263-014-0432-4. Epub 2014 Sep 27.


N-acetylaspartate and neurofilaments as biomarkers of axonal damage in patients with progressive forms of multiple sclerosis.

Trentini A, Comabella M, Tintoré M, Koel-Simmelink MJ, Killestein J, Roos B, Rovira A, Korth C, Ottis P, Blankenstein MA, Montalban X, Bellini T, Teunissen CE.

J Neurol. 2014 Dec;261(12):2338-43. doi: 10.1007/s00415-014-7507-4. Epub 2014 Sep 17.


Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma.

Tucker BA, Solivan-Timpe F, Roos BR, Anfinson KR, Robin AL, Wiley LA, Mullins RF, Fingert JH.

J Stem Cell Res Ther. 2014 Jan 25;3(5):161.


Dietary manipulation of platelet function.

Bachmair EM, Ostertag LM, Zhang X, de Roos B.

Pharmacol Ther. 2014 Nov;144(2):97-113. doi: 10.1016/j.pharmthera.2014.05.008. Epub 2014 May 21. Review.


TBK1 gene duplication and normal-tension glaucoma.

Ritch R, Darbro B, Menon G, Khanna CL, Solivan-Timpe F, Roos BR, Sarfarzi M, Kawase K, Yamamoto T, Robin AL, Lotery AJ, Fingert JH.

JAMA Ophthalmol. 2014 May;132(5):544-8. doi: 10.1001/jamaophthalmol.2014.104.


Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells.

Aenlle KK, Curtis KM, Roos BA, Howard GA.

Mol Endocrinol. 2014 May;28(5):722-30. doi: 10.1210/me.2013-1286. Epub 2014 Mar 27.


Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 diabetes.

Zhang X, McGeoch SC, Megson IL, MacRury SM, Johnstone AM, Abraham P, Pearson DW, de Roos B, Holtrop G, O'Kennedy N, Lobley GE.

Mol Nutr Food Res. 2014 Jun;58(6):1322-32. doi: 10.1002/mnfr.201300820. Epub 2014 Mar 7.


24R,25-dihydroxyvitamin D3 promotes the osteoblastic differentiation of human mesenchymal stem cells.

Curtis KM, Aenlle KK, Roos BA, Howard GA.

Mol Endocrinol. 2014 May;28(5):644-58. doi: 10.1210/me.2013-1241. Epub 2014 Mar 5.


Platelet-derived microparticle count and surface molecule expression differ between subjects with and without type 2 diabetes, independently of obesity status.

Zhang X, McGeoch SC, Johnstone AM, Holtrop G, Sneddon AA, MacRury SM, Megson IL, Pearson DW, Abraham P, De Roos B, Lobley GE, O'Kennedy N.

J Thromb Thrombolysis. 2014 May;37(4):455-63. doi: 10.1007/s11239-013-1000-2.


Bound phytophenols from ready-to-eat cereals: comparison with other plant-based foods.

Neacsu M, McMonagle J, Fletcher RJ, Scobbie L, Duncan GJ, Cantlay L, de Roos B, Duthie GG, Russell WR.

Food Chem. 2013 Dec 1;141(3):2880-6. doi: 10.1016/j.foodchem.2013.05.023. Epub 2013 May 17.


Circumferential proximal femoral allografts in revision hip arthroplasty: four to 20 years follow-up.

Roos BD, Roos MV, Camisa A Jr.

Hip Int. 2013 Jan-Feb;23(1):66-71. doi: 10.5301/HIP.2013.10757.


TBK1 and flanking genes in human retina.

Fingert JH, Darbro BW, Qian Q, Van Rheeden R, Miller K, Riker M, Solivan-Timpe F, Roos BR, Robin AL, Mullins RF.

Ophthalmic Genet. 2014 Mar;35(1):35-40. doi: 10.3109/13816810.2013.768674. Epub 2013 Feb 20.

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