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Items: 1 to 50 of 252

1.

Loricrin confers photoprotective function against UVB in corneocytes.

Ishitsuka Y, Roop DR.

J Invest Dermatol. 2018 Jun 19. pii: S0022-202X(18)32223-1. doi: 10.1016/j.jid.2018.06.164. [Epub ahead of print] No abstract available.

PMID:
29932941
2.

High-efficiency RNA-based reprogramming of human primary fibroblasts.

Kogut I, McCarthy SM, Pavlova M, Astling DP, Chen X, Jakimenko A, Jones KL, Getahun A, Cambier JC, Pasmooij AMG, Jonkman MF, Roop DR, Bilousova G.

Nat Commun. 2018 Feb 21;9(1):745. doi: 10.1038/s41467-018-03190-3.

3.

Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem Cells.

Goldstein NB, Koster MI, Jones KL, Gao B, Hoaglin LG, Robinson SE, Wright MJ, Birlea SI, Luman A, Lambert KA, Shellman YG, Fujita M, Robinson WA, Roop DR, Norris DA, Birlea SA.

J Invest Dermatol. 2018 Mar;138(3):657-668. doi: 10.1016/j.jid.2017.09.040. Epub 2017 Oct 17.

PMID:
29054607
4.

INTU is essential for oncogenic Hh signaling through regulating primary cilia formation in basal cell carcinoma.

Yang N, Leung EL, Liu C, Li L, Eguether T, Jun Yao XJ, Jones EC, Norris DA, Liu A, Clark RA, Roop DR, Pazour GJ, Shroyer KR, Chen J.

Oncogene. 2017 Aug 31;36(35):4997-5005. doi: 10.1038/onc.2017.117. Epub 2017 May 1.

5.

Shared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease.

Gaskill C, Marriott S, Pratap S, Menon S, Hedges LK, Fessel JP, Kropski JA, Ames D, Wheeler L, Loyd JE, Hemnes AR, Roop DR, Klemm DJ, Austin ED, Majka SM.

Pulm Circ. 2016 Dec;6(4):483-497. doi: 10.1086/688314.

6.

Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization.

Birlea SA, Costin GE, Roop DR, Norris DA.

Med Res Rev. 2017 Jul;37(4):907-935. doi: 10.1002/med.21426. Epub 2016 Dec 28. Review.

7.

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2.

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A.

J Natl Cancer Inst. 2016 Sep 15;109(1). pii: djw189. doi: 10.1093/jnci/djw189. Print 2017 Jan.

8.

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.

Zhang L, Ferreyros M, Feng W, Hupe M, Crumrine DA, Chen J, Elias PM, Holleran WM, Niswander L, Hohl D, Williams T, Torchia EC, Roop DR.

PLoS One. 2016 Aug 23;11(8):e0161465. doi: 10.1371/journal.pone.0161465. eCollection 2016.

9.

Proteomic Analysis of Loricrin Knockout Mouse Epidermis.

Rice RH, Durbin-Johnson BP, Ishitsuka Y, Salemi M, Phinney BS, Rocke DM, Roop DR.

J Proteome Res. 2016 Aug 5;15(8):2560-6. doi: 10.1021/acs.jproteome.6b00108. Epub 2016 Jul 26.

PMID:
27418529
10.

Isolating RNA from precursor and mature melanocytes from human vitiligo and normal skin using laser capture microdissection.

Goldstein NB, Koster MI, Hoaglin LG, Wright MJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA.

Exp Dermatol. 2016 Oct;25(10):805-11. doi: 10.1111/exd.13072.

11.

Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin.

Ishitsuka Y, Huebner AJ, Rice RH, Koch PJ, Speransky VV, Steven AC, Roop DR.

J Invest Dermatol. 2016 Aug;136(8):1656-63. doi: 10.1016/j.jid.2016.04.022. Epub 2016 May 7.

12.

Correction: A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

Kumar V, Bouameur JE, Bär J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Löffler-Wirth H, Seibel P, Magin TM.

J Cell Biol. 2016 Mar 28;212(7):877. doi: 10.1083/jcb.20140414703042016c. Epub 2016 Mar 21. No abstract available.

13.

Correction of Hair Shaft Defects through Allele-Specific Silencing of Mutant Krt75.

Liu Y, Snedecor ER, Zhang X, Xu Y, Huang L, Jones EC, Zhang L, Clark RA, Roop DR, Qin C, Chen J.

J Invest Dermatol. 2016 Jan;136(1):45-51. doi: 10.1038/JID.2015.375.

14.

A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma.

Bowles DW, Keysar SB, Eagles JR, Wang G, Glogowska MJ, McDermott JD, Le PN, Gao D, Ray CE, Rochon PJ, Roop DR, Tan AC, Serracino HS, Jimeno A.

Oral Oncol. 2016 Feb;53:74-9. doi: 10.1016/j.oraloncology.2015.11.014. Epub 2015 Dec 15.

15.

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

Kumar V, Bouameur JE, Bär J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Löffler-Wirth H, Seibel P, Magin TM.

J Cell Biol. 2015 Dec 7;211(5):1057-75. doi: 10.1083/jcb.201404147. Erratum in: J Cell Biol. 2016 Mar 28;212(7):877.

16.

MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells.

Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R.

Elife. 2015 Jul 23;4. doi: 10.7554/eLife.07004.

17.

XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer.

Morton JJ, Bird G, Keysar SB, Astling DP, Lyons TR, Anderson RT, Glogowska MJ, Estes P, Eagles JR, Le PN, Gan G, McGettigan B, Fernandez P, Padilla-Just N, Varella-Garcia M, Song JI, Bowles DW, Schedin P, Tan AC, Roop DR, Wang XJ, Refaeli Y, Jimeno A.

Oncogene. 2016 Jan 21;35(3):290-300. doi: 10.1038/onc.2015.94. Epub 2015 Apr 20.

18.

Narrow Band Ultraviolet B Treatment for Human Vitiligo Is Associated with Proliferation, Migration, and Differentiation of Melanocyte Precursors.

Goldstein NB, Koster MI, Hoaglin LG, Spoelstra NS, Kechris KJ, Robinson SE, Robinson WA, Roop DR, Norris DA, Birlea SA.

J Invest Dermatol. 2015 Aug;135(8):2068-2076. doi: 10.1038/jid.2015.126. Epub 2015 Mar 30.

19.

Induced pluripotent stem cells in dermatology: potentials, advances, and limitations.

Bilousova G, Roop DR.

Cold Spring Harb Perspect Med. 2014 Nov 3;4(11):a015164. doi: 10.1101/cshperspect.a015164. Review.

20.

Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.

Rorke EA, Adhikary G, Young CA, Roop DR, Eckert RL.

J Invest Dermatol. 2015 Jan;135(1):170-180. doi: 10.1038/jid.2014.310. Epub 2014 Aug 22.

21.

Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting.

van Steensel MAM, Coulombe PA, Kaspar RL, Milstone LM, McLean IWH, Roop DR, Smith FJD, Sprecher E, Schwartz ME.

J Invest Dermatol. 2014 Mar;134(3):588-591. doi: 10.1038/jid.2013.392. No abstract available.

22.

Differentiation of human induced pluripotent stem cells into a keratinocyte lineage.

Kogut I, Roop DR, Bilousova G.

Methods Mol Biol. 2014;1195:1-12. doi: 10.1007/7651_2013_64.

23.

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.

Schäfer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S.

EMBO Mol Med. 2014 Apr;6(4):442-57. doi: 10.1002/emmm.201303281. Epub 2014 Feb 6.

24.

Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation.

Dallaglio K, Petrachi T, Marconi A, Truzzi F, Lotti R, Saltari A, Morandi P, Puviani M, Maiorana A, Roop DR, Pincelli C.

Int J Mol Sci. 2013 Sep 26;14(10):19540-55. doi: 10.3390/ijms141019540.

25.

Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.

White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ.

J Clin Invest. 2013 Oct;123(10):4390-404. doi: 10.1172/JCI65856. Epub 2013 Sep 3.

26.

Genetic manipulation of keratinocyte stem cells with lentiviral vectors.

Yasuda M, Claypool DJ, Guevara E, Roop DR, Chen J.

Methods Mol Biol. 2013;989:143-51. doi: 10.1007/978-1-62703-330-5_12.

PMID:
23483393
27.

Generation of functional multipotent keratinocytes from mouse induced pluripotent stem cells.

Bilousova G, Roop DR.

Methods Mol Biol. 2013;961:337-50. doi: 10.1007/978-1-62703-227-8_22.

PMID:
23325655
28.

Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.

Huebner AJ, Dai D, Morasso M, Schmidt EE, Schäfer M, Werner S, Roop DR.

Dev Cell. 2012 Dec 11;23(6):1238-46. doi: 10.1016/j.devcel.2012.11.002.

29.

A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis.

Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA.

PLoS One. 2012;7(11):e50634. doi: 10.1371/journal.pone.0050634. Epub 2012 Nov 30. Erratum in: PLoS One. 2014;9(2):e91624.

30.

Mimicking hair disorders by genetic manipulation of organ-cultured human hair follicles.

Chen J, Roop DR.

J Invest Dermatol. 2012 Oct;132(10):2312-2314. doi: 10.1038/jid.2012.243.

31.

ALDH1A isozymes are markers of human melanoma stem cells and potential therapeutic targets.

Luo Y, Dallaglio K, Chen Y, Robinson WA, Robinson SE, McCarter MD, Wang J, Gonzalez R, Thompson DC, Norris DA, Roop DR, Vasiliou V, Fujita M.

Stem Cells. 2012 Oct;30(10):2100-13. doi: 10.1002/stem.1193.

32.

Aurora kinase-A deficiency during skin development impairs cell division and stratification.

Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR.

J Invest Dermatol. 2013 Jan;133(1):78-86. doi: 10.1038/jid.2012.249. Epub 2012 Jul 26.

33.

Side population cells from human melanoma tumors reveal diverse mechanisms for chemoresistance.

Luo Y, Ellis LZ, Dallaglio K, Takeda M, Robinson WA, Robinson SE, Liu W, Lewis KD, McCarter MD, Gonzalez R, Norris DA, Roop DR, Spritz RA, Ahn NG, Fujita M.

J Invest Dermatol. 2012 Oct;132(10):2440-2450. doi: 10.1038/jid.2012.161. Epub 2012 May 24.

34.

Montagna Symposium 2011: 60th Anniversary--Advances in Science and Medicine Catalyzed by Pioneering Skin Research.

Yuspa SH, Kraemer KH, Dlugosz AA, Roop DR, Kulesz-Martin M, Bickenbach JR.

J Invest Dermatol. 2012 May;132(5):1317-20. doi: 10.1038/jid.2011.480. No abstract available.

35.

A fitness model for melanoma-initiating cells.

Kubick BJ, Roop DR.

Pigment Cell Melanoma Res. 2011 Jun;24(3):396-7. No abstract available.

PMID:
22489315
36.

Myc, Aurora Kinase A, and mutant p53(R172H) co-operate in a mouse model of metastatic skin carcinoma.

Torchia EC, Caulin C, Acin S, Terzian T, Kubick BJ, Box NF, Roop DR.

Oncogene. 2012 May 24;31(21):2680-90. doi: 10.1038/onc.2011.441. Epub 2011 Oct 3.

37.

Gain-of-function mutant p53 but not p53 deletion promotes head and neck cancer progression in response to oncogenic K-ras.

Acin S, Li Z, Mejia O, Roop DR, El-Naggar AK, Caulin C.

J Pathol. 2011 Dec;225(4):479-89. doi: 10.1002/path.2971. Epub 2011 Sep 26.

38.

Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo.

Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC, Chow KS, Klemm DJ, Roop DR, Majka SM.

Stem Cells. 2011 Feb;29(2):206-16. doi: 10.1002/stem.566.

39.

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models.

Terzian T, Dumble M, Arbab F, Thaller C, Donehower LA, Lozano G, Justice MJ, Roop DR, Box NF.

J Pathol. 2011 Aug;224(4):540-52. doi: 10.1002/path.2891. Epub 2011 Jun 14.

40.

Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer.

Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y.

Oncogene. 2011 Oct 27;30(43):4399-409. doi: 10.1038/onc.2011.147. Epub 2011 May 2.

41.

Differentiation of mouse induced pluripotent stem cells into a multipotent keratinocyte lineage.

Bilousova G, Chen J, Roop DR.

J Invest Dermatol. 2011 Apr;131(4):857-64. doi: 10.1038/jid.2010.364. Epub 2010 Dec 9.

42.

Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.

Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J.

J Invest Dermatol. 2011 Feb;131(2):302-10. doi: 10.1038/jid.2010.306. Epub 2010 Oct 21.

43.

Altering cell fate: from thymus epithelium to skin stem cells.

Bilousova G, Roop DR.

Cell Stem Cell. 2010 Oct 8;7(4):419-20. doi: 10.1016/j.stem.2010.09.007.

44.

p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.

Terzian T, Torchia EC, Dai D, Robinson SE, Murao K, Stiegmann RA, Gonzalez V, Boyle GM, Powell MB, Pollock PM, Lozano G, Robinson WA, Roop DR, Box NF.

Pigment Cell Melanoma Res. 2010 Dec;23(6):781-94. doi: 10.1111/j.1755-148X.2010.00773.x.

45.

Are stem cell niches shared for skin cancers?

Box NF, Torchia EC, Roop DR.

Pigment Cell Melanoma Res. 2010 Aug;23(4):517-20. doi: 10.1111/j.1755-148X.2010.00727.x. Epub 2010 Jun 8. No abstract available.

46.

Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration.

Li F, Huang Q, Chen J, Peng Y, Roop DR, Bedford JS, Li CY.

Sci Signal. 2010 Feb 23;3(110):ra13. doi: 10.1126/scisignal.2000634.

47.

The effect of c-myc on stem cell fate influences skin tumor phenotype.

Honeycutt KA, Waikel RL, Koster MI, Wang XJ, Roop DR.

Mol Carcinog. 2010 Apr;49(4):315-9. doi: 10.1002/mc.20617.

PMID:
20146250
48.

Treasure or artifact: a decade of p63 research speaks for itself.

Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI.

Cell Death Differ. 2010 Jan;17(1):180-3; author reply 184-6. doi: 10.1038/cdd.2009.157. No abstract available.

49.

A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors.

Torchia EC, Chen Y, Sheng H, Katayama H, Fitzpatrick J, Brinkley WR, Caulin C, Sen S, Roop DR.

Cancer Res. 2009 Sep 15;69(18):7207-15. doi: 10.1158/0008-5472.CAN-09-1059. Epub 2009 Sep 8.

50.

DeltaNp63 knockdown mice: A mouse model for AEC syndrome.

Koster MI, Marinari B, Payne AS, Kantaputra PN, Costanzo A, Roop DR.

Am J Med Genet A. 2009 Sep;149A(9):1942-7. doi: 10.1002/ajmg.a.32794.

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