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Molecular basis of inhibition of acid sensing ion channel 1A by diminazene.

Krauson AJ, Rooney JG, Carattino MD.

PLoS One. 2018 May 21;13(5):e0196894. doi: 10.1371/journal.pone.0196894. eCollection 2018.


Multicentre, cross-cultural, population-based, case-control study of physical activity as risk factor for amyotrophic lateral sclerosis.

Visser AE, Rooney JPK, D'Ovidio F, Westeneng HJ, Vermeulen RCH, Beghi E, Chiò A, Logroscino G, Hardiman O, Veldink JH, van den Berg LH; Euro-MOTOR consortium.

J Neurol Neurosurg Psychiatry. 2018 Aug;89(8):797-803. doi: 10.1136/jnnp-2017-317724. Epub 2018 Apr 23.


Referral bias in ALS epidemiological studies.

Logroscino G, Marin B, Piccininni M, Arcuti S, Chiò A, Hardiman O, Rooney J, Zoccolella S, Couratier P, Preux PM, Beghi E; for EURALS.

PLoS One. 2018 Apr 16;13(4):e0195821. doi: 10.1371/journal.pone.0195821. eCollection 2018.


Genetic polymorphisms of GRIN2A and GRIN2B modify the neurobehavioral effects of low-level lead exposure in children.

Rooney JPK, Woods NF, Martin MD, Woods JS.

Environ Res. 2018 Aug;165:1-10. doi: 10.1016/j.envres.2018.04.001. Epub 2018 Apr 11.


Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model.

Westeneng HJ, Debray TPA, Visser AE, van Eijk RPA, Rooney JPK, Calvo A, Martin S, McDermott CJ, Thompson AG, Pinto S, Kobeleva X, Rosenbohm A, Stubendorff B, Sommer H, Middelkoop BM, Dekker AM, van Vugt JJFA, van Rheenen W, Vajda A, Heverin M, Kazoka M, Hollinger H, Gromicho M, Körner S, Ringer TM, Rödiger A, Gunkel A, Shaw CE, Bredenoord AL, van Es MA, Corcia P, Couratier P, Weber M, Grosskreutz J, Ludolph AC, Petri S, de Carvalho M, Van Damme P, Talbot K, Turner MR, Shaw PJ, Al-Chalabi A, Chiò A, Hardiman O, Moons KGM, Veldink JH, van den Berg LH.

Lancet Neurol. 2018 May;17(5):423-433. doi: 10.1016/S1474-4422(18)30089-9. Epub 2018 Mar 26.


ASIC3 fine-tunes bladder sensory signaling.

Montalbetti N, Rooney JG, Marciszyn AL, Carattino MD.

Am J Physiol Renal Physiol. 2018 Mar 21. doi: 10.1152/ajprenal.00630.2017. [Epub ahead of print]


Daily and Nondaily Oral Preexposure Prophylaxis in Men and Transgender Women Who Have Sex With Men: The Human Immunodeficiency Virus Prevention Trials Network 067/ADAPT Study.

Grant RM, Mannheimer S, Hughes JP, Hirsch-Moverman Y, Loquere A, Chitwarakorn A, Curlin ME, Li M, Amico KR, Hendrix CW, Anderson PL, Dye BJ, Marzinke MA, Piwowar-Manning E, McKinstry L, Elharrar V, Stirratt M, Rooney JF, Eshleman SH, McNicholl JM, van Griensven F, Holtz TH.

Clin Infect Dis. 2018 May 17;66(11):1712-1721. doi: 10.1093/cid/cix1086.


Exploring the disclosure decisions made by physiotherapists with a specific learning difficulty.

Yeowell G, Rooney J, Goodwin PC.

Physiotherapy. 2018 Jun;104(2):203-208. doi: 10.1016/ Epub 2017 Oct 27.


The researchers' role in knowledge translation: a realist evaluation of the development and implementation of diagnostic pathways for cancer in two United Kingdom localities.

Banks J, Wye L, Hall N, Rooney J, Walter FM, Hamilton W, Gjini A, Rubin G.

Health Res Policy Syst. 2017 Dec 13;15(1):103. doi: 10.1186/s12961-017-0267-8.


Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder.

Walker G, Römann P, Poller B, Löbmann K, Grohganz H, Rooney JS, Huff GS, Smith GPS, Rades T, Gordon KC, Strachan CJ, Fraser-Miller SJ.

Mol Pharm. 2017 Dec 4;14(12):4675-4684. doi: 10.1021/acs.molpharmaceut.7b00803. Epub 2017 Nov 16.


Trauma and amyotrophic lateral sclerosis: a european population-based case-control study from the EURALS consortium.

Pupillo E, Poloni M, Bianchi E, Giussani G, Logroscino G, Zoccolella S, Chiò A, Calvo A, Corbo M, Lunetta C, Marin B, Mitchell D, Hardiman O, Rooney J, Stevic Z, Bandettini di Poggio M, Filosto M, Cotelli MS, Perini M, Riva N, Tremolizzo L, Vitelli E, Damiani D, Beghi E; EURALS Consortium†.

Amyotroph Lateral Scler Frontotemporal Degener. 2018 Feb;19(1-2):118-125. doi: 10.1080/21678421.2017.1386687. Epub 2017 Oct 24.


Daily and non-daily pre-exposure prophylaxis in African women (HPTN 067/ADAPT Cape Town Trial): a randomised, open-label, phase 2 trial.

Bekker LG, Roux S, Sebastien E, Yola N, Amico KR, Hughes JP, Marzinke MA, Hendrix CW, Anderson PL, Elharrar V, Stirratt M, Rooney JF, Piwowar-Manning E, Eshleman SH, McKinstry L, Li M, Dye BJ, Grant RM; HPTN 067 (ADAPT) study team.

Lancet HIV. 2018 Feb;5(2):e68-e78. doi: 10.1016/S2352-3018(17)30156-X. Epub 2017 Oct 3.


From the Cover: Genomic Effects of Androstenedione and Sex-Specific Liver Cancer Susceptibility in Mice.

Rooney JP, Ryan N, Chorley BN, Hester SD, Kenyon EM, Schmid JE, George BJ, Hughes MF, Sey YM, Tennant A, MacMillan DK, Simmons JE, McQueen CA, Pandiri A, Wood CE, Corton JC.

Toxicol Sci. 2017 Nov 1;160(1):15-29. doi: 10.1093/toxsci/kfx153.


A qualitative study exploring midwives' perceptions and knowledge of maternal obesity: Reflecting on their experiences of providing healthy eating and weight management advice to pregnant women.

McCann MT, Newson L, Burden C, Rooney JS, Charnley MS, Abayomi JC.

Matern Child Nutr. 2018 Apr;14(2):e12520. doi: 10.1111/mcn.12520. Epub 2017 Sep 25.


Plasma Tenofovir Levels to Support Adherence to TDF/FTC Preexposure Prophylaxis for HIV Prevention in MSM in Los Angeles, California.

Landovitz RJ, Beymer M, Kofron R, Amico KR, Psaros C, Bushman L, Anderson PL, Flynn R, Lee DP, Bolan RK, Jordan WC, Tseng CH, Dierst-Davies R, Rooney J, Wohl AR.

J Acquir Immune Defic Syndr. 2017 Dec 15;76(5):501-511. doi: 10.1097/QAI.0000000000001538.


Safety and Feasibility of Antiretroviral Preexposure Prophylaxis for Adolescent Men Who Have Sex With Men Aged 15 to 17 Years in the United States.

Hosek SG, Landovitz RJ, Kapogiannis B, Siberry GK, Rudy B, Rutledge B, Liu N, Harris DR, Mulligan K, Zimet G, Mayer KH, Anderson P, Kiser JJ, Lally M, Brothers J, Bojan K, Rooney J, Wilson CM.

JAMA Pediatr. 2017 Nov 1;171(11):1063-1071. doi: 10.1001/jamapediatrics.2017.2007.


A case-control study of hormonal exposures as etiologic factors for ALS in women: Euro-MOTOR.

Rooney JPK, Visser AE, D'Ovidio F, Vermeulen R, Beghi E, Chio A, Veldink JH, Logroscino G, van den Berg LH, Hardiman O; Euro-MOTOR Consortium.

Neurology. 2017 Sep 19;89(12):1283-1290. doi: 10.1212/WNL.0000000000004390. Epub 2017 Aug 23.


Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women: A Phase 2 Randomized Trial.

Gulick RM, Wilkin TJ, Chen YQ, Landovitz RJ, Amico KR, Young AM, Richardson P, Marzinke MA, Hendrix CW, Eshleman SH, McGowan I, Cottle LM, Andrade A, Marcus C, Klingman KL, Chege W, Rinehart AR, Rooney JF, Andrew P, Salata RA, Siegel M, Manabe YC, Frank I, Ho K, Santana J, Stekler JD, Swaminathan S, McCauley M, Hodder S, Mayer KH.

Ann Intern Med. 2017 Sep 19;167(6):384-393. doi: 10.7326/M17-0520. Epub 2017 Aug 22.


Critical issues in ALS case-control studies: the case of the Euro-MOTOR study.

D'Ovidio F, Rooney JPK, Visser AE, Vermeulen RCH, Veldink JH, Van Den Berg LH, Hardiman O, Logroscino G, Chiò A, Beghi E; Euro-MOTOR Group.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Aug;18(5-6):411-418. doi: 10.1080/21678421.2017.1285939. Epub 2017 Feb 10.


PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling.

Rosen MB, Das KP, Rooney J, Abbott B, Lau C, Corton JC.

Toxicology. 2017 Jul 15;387:95-107. doi: 10.1016/j.tox.2017.05.013. Epub 2017 May 27.


Benefits, pitfalls, and future design of population-based registers in neurodegenerative disease.

Rooney JPK, Brayne C, Tobin K, Logroscino G, Glymour MM, Hardiman O.

Neurology. 2017 Jun 13;88(24):2321-2329. doi: 10.1212/WNL.0000000000004038. Epub 2017 May 17. Review.


Presentation and care of a family with Huntington disease in a resource-limited community.

Charles J, Lessey L, Rooney J, Prokop I, Yearwood K, Da Breo H, Rooney P, Walker RH, Sobering AK.

J Clin Mov Disord. 2017 Apr 12;4:4. doi: 10.1186/s40734-017-0050-6. eCollection 2017.


Single-dose pharmacokinetics of tenofovir alafenamide and its active metabolite in the mucosal tissues.

Cottrell ML, Garrett KL, Prince HMA, Sykes C, Schauer A, Emerson CW, Peery A, Rooney JF, McCallister S, Gay C, Kashuba ADM.

J Antimicrob Chemother. 2017 Jun 1;72(6):1731-1740. doi: 10.1093/jac/dkx064.


Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice.

Kumar R, Mota LC, Litoff EJ, Rooney JP, Boswell WT, Courter E, Henderson CM, Hernandez JP, Corton JC, Moore DD, Baldwin WS.

PLoS One. 2017 Mar 28;12(3):e0174355. doi: 10.1371/journal.pone.0174355. eCollection 2017.


The changing picture of amyotrophic lateral sclerosis: lessons from European registers.

Hardiman O, Al-Chalabi A, Brayne C, Beghi E, van den Berg LH, Chio A, Martin S, Logroscino G, Rooney J.

J Neurol Neurosurg Psychiatry. 2017 Jul;88(7):557-563. doi: 10.1136/jnnp-2016-314495. Epub 2017 Mar 11. Review.


Behaviours, thoughts and perceptions around mealtime insulin usage and wastage among people with type 1 and type 2 diabetes mellitus: A cross-sectional survey study.

Van Brunt K, Pedersini R, Rooney J, Corrigan SM.

Diabetes Res Clin Pract. 2017 Apr;126:30-42. doi: 10.1016/j.diabres.2016.12.002. Epub 2016 Dec 18.


MTN-017: A Rectal Phase 2 Extended Safety and Acceptability Study of Tenofovir Reduced-Glycerin 1% Gel.

Cranston RD, Lama JR, Richardson BA, Carballo-Diéguez A, Kunjara Na Ayudhya RP, Liu K, Patterson KB, Leu CS, Galaska B, Jacobson CE, Parikh UM, Marzinke MA, Hendrix CW, Johnson S, Piper JM, Grossman C, Ho KS, Lucas J, Pickett J, Bekker LG, Chariyalertsak S, Chitwarakorn A, Gonzales P, Holtz TH, Liu AY, Mayer KH, Zorrilla C, Schwartz JL, Rooney J, McGowan I; MTN-017 Protocol Team.

Clin Infect Dis. 2017 Mar 1;64(5):614-620. doi: 10.1093/cid/ciw832.


Correction: Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes.

Luz AL, Rooney JP, Kubik LL, Gonzalez CP, Song DH, Meyer JN.

PLoS One. 2016 Dec 15;11(12):e0168738. doi: 10.1371/journal.pone.0168738. eCollection 2016.


Comparison of Reef Fish Survey Data Gathered by Open and Closed Circuit SCUBA Divers Reveals Differences in Areas With Higher Fishing Pressure.

Gray AE, Williams ID, Stamoulis KA, Boland RC, Lino KC, Hauk BB, Leonard JC, Rooney JJ, Asher JM, Lopes KH Jr, Kosaki RK.

PLoS One. 2016 Dec 9;11(12):e0167724. doi: 10.1371/journal.pone.0167724. eCollection 2016.


Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI).

Elamin M, Pinto-Grau M, Burke T, Bede P, Rooney J, O'Sullivan M, Lonergan K, Kirby E, Quinlan E, Breen N, Vajda A, Heverin M, Pender N, Hardiman O.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 Feb;18(1-2):68-73. doi: 10.1080/21678421.2016.1248976. Epub 2016 Nov 28.


What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis.

Rooney J, Burke T, Vajda A, Heverin M, Hardiman O.

J Neurol Neurosurg Psychiatry. 2017 May;88(5):381-385. doi: 10.1136/jnnp-2016-314661. Epub 2016 Nov 25.


Phase 2 Study of the Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Men Who Have Sex With Men (HPTN 069/ACTG A5305).

Gulick RM, Wilkin TJ, Chen YQ, Landovitz RJ, Amico KR, Young AM, Richardson P, Marzinke MA, Hendrix CW, Eshleman SH, McGowan I, Cottle LM, Andrade A, Marcus C, Klingman KL, Chege W, Rinehart AR, Rooney JF, Andrew P, Salata RA, Magnus M, Farley JE, Liu A, Frank I, Ho K, Santana J, Stekler JD, McCauley M, Mayer KH.

J Infect Dis. 2017 Jan 15;215(2):238-246. doi: 10.1093/infdis/jiw525.


A comprehensive investigation of mesophotic coral ecosystems in the Hawaiian Archipelago.

Pyle RL, Boland R, Bolick H, Bowen BW, Bradley CJ, Kane C, Kosaki RK, Langston R, Longenecker K, Montgomery A, Parrish FA, Popp BN, Rooney J, Smith CM, Wagner D, Spalding HL.

PeerJ. 2016 Oct 4;4:e2475. eCollection 2016.


C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis.

Rooney J, Fogh I, Westeneng HJ, Vajda A, McLaughlin R, Heverin M, Jones A, van Eijk R, Calvo A, Mazzini L, Shaw C, Morrison K, Shaw PJ, Robberecht W, Van Damme P, Al-Chalabi A, van den Berg L, Chiò A, Veldink J, Hardiman O.

J Neurol Neurosurg Psychiatry. 2017 Apr;88(4):281. doi: 10.1136/jnnp-2016-314093. Epub 2016 Sep 23.


An HIV Preexposure Prophylaxis Demonstration Project and Safety Study for Young MSM.

Hosek SG, Rudy B, Landovitz R, Kapogiannis B, Siberry G, Rutledge B, Liu N, Brothers J, Mulligan K, Zimet G, Lally M, Mayer KH, Anderson P, Kiser J, Rooney JF, Wilson CM; Adolescent Trials Network (ATN) for HIVAIDS Interventions.

J Acquir Immune Defic Syndr. 2017 Jan 1;74(1):21-29.


Chemoprophylaxis With Oral Emtricitabine and Tenofovir Alafenamide Combination Protects Macaques From Rectal Simian/Human Immunodeficiency Virus Infection.

Massud I, Mitchell J, Babusis D, Deyounks F, Ray AS, Rooney JF, Heneine W, Miller MD, García-Lerma JG.

J Infect Dis. 2016 Oct 1;214(7):1058-62. doi: 10.1093/infdis/jiw312. Epub 2016 Jul 27.


The implementation of rare events logistic regression to predict the distribution of mesophotic hard corals across the main Hawaiian Islands.

Veazey LM, Franklin EC, Kelley C, Rooney J, Frazer LN, Toonen RJ.

PeerJ. 2016 Jul 6;4:e2189. doi: 10.7717/peerj.2189. eCollection 2016.


Head and Neck Soft Tissue Sarcomas Treated with Radiation Therapy.

Vitzthum LK, Brown LC, Rooney JW, Foote RL.

Rare Tumors. 2016 Jun 28;8(2):6165. doi: 10.4081/rt.2016.6165. eCollection 2016 Jun 28.


Age-period-cohort analysis of trends in amyotrophic lateral sclerosis incidence.

Tobin K, Gilthorpe MS, Rooney J, Heverin M, Vajda A, Staines A, Hardiman O.

J Neurol. 2016 Oct;263(10):1919-26. doi: 10.1007/s00415-016-8215-z. Epub 2016 Jul 2.


Mechanical Failure of Revision Knee Prosthesis at both Femoral and Tibial Modular Metaphyseal Stem Junctions.

Woodgate IG, Rooney J, Mulford JS, Gillies RM.

J Orthop Case Rep. 2016 Jan-Mar;6(1):40-3. doi: 10.13107/jocr.2250-0685.373.


Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.

Fogh I, Lin K, Tiloca C, Rooney J, Gellera C, Diekstra FP, Ratti A, Shatunov A, van Es MA, Proitsi P, Jones A, Sproviero W, Chiò A, McLaughlin RL, Sorarù G, Corrado L, Stahl D, Del Bo R, Cereda C, Castellotti B, Glass JD, Newhouse S, Dobson R, Smith BN, Topp S, van Rheenen W, Meininger V, Melki J, Morrison KE, Shaw PJ, Leigh PN, Andersen PM, Comi GP, Ticozzi N, Mazzini L, D'Alfonso S, Traynor BJ, Van Damme P, Robberecht W, Brown RH, Landers JE, Hardiman O, Lewis CM, van den Berg LH, Shaw CE, Veldink JH, Silani V, Al-Chalabi A, Powell J.

JAMA Neurol. 2016 Jul 1;73(7):812-20. doi: 10.1001/jamaneurol.2016.1114.


Survival analysis of geospatial factors in the Irish ALS cohort.

Rooney J, Heverin M, Vajda A, Burke T, Galvin M, Tobin K, Elamin M, Staines A, Hardiman O.

Amyotroph Lateral Scler Frontotemporal Degener. 2016 Oct - Nov;17(7-8):555-560. Epub 2016 May 4.


Comments on the "Effects of in utero exposure to polychlorinated biphenyls, methylmercury, and polyunsaturated fatty acids on birth size".

Dórea JG, Rooney J.

Sci Total Environ. 2016 Feb 15;544:1136-7. doi: 10.1016/j.scitotenv.2015.10.105. No abstract available.


No association between soil constituents and amyotrophic lateral sclerosis relative risk in Ireland.

Rooney J, Vajda A, Heverin M, Crampsie A, Tobin K, McLaughlin R, Staines A, Hardiman O.

Environ Res. 2016 May;147:102-7. doi: 10.1016/j.envres.2016.01.038. Epub 2016 Feb 6.


PCR-Based Analysis of Mitochondrial DNA Copy Number, Mitochondrial DNA Damage, and Nuclear DNA Damage.

Gonzalez-Hunt CP, Rooney JP, Ryde IT, Anbalagan C, Joglekar R, Meyer JN.

Curr Protoc Toxicol. 2016 Feb 1;67:20.11.1-20.11.25. doi: 10.1002/0471140856.tx2011s67.


On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.

Molina JM, Capitant C, Spire B, Pialoux G, Cotte L, Charreau I, Tremblay C, Le Gall JM, Cua E, Pasquet A, Raffi F, Pintado C, Chidiac C, Chas J, Charbonneau P, Delaugerre C, Suzan-Monti M, Loze B, Fonsart J, Peytavin G, Cheret A, Timsit J, Girard G, Lorente N, Préau M, Rooney JF, Wainberg MA, Thompson D, Rozenbaum W, Doré V, Marchand L, Simon MC, Etien N, Aboulker JP, Meyer L, Delfraissy JF; ANRS IPERGAY Study Group.

N Engl J Med. 2015 Dec 3;373(23):2237-46. doi: 10.1056/NEJMoa1506273. Epub 2015 Dec 1.


Spatial cluster analysis of population amyotrophic lateral sclerosis risk in Ireland.

Bradley WG, Stommel EW, Shi X, Torbick NM, Caller TA, Sabel CE, Rooney JP, Staines A, Hardiman O.

Neurology. 2015 Nov 17;85(20):1822-3. doi: 10.1212/01.wnl.0000473800.89178.a9. No abstract available.


Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans.

Luz AL, Smith LL, Rooney JP, Meyer JN.

Curr Protoc Toxicol. 2015 Nov 2;66:25.7.1-15. doi: 10.1002/0471140856.tx2507s66.


Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial.

McCormack S, Dunn DT, Desai M, Dolling DI, Gafos M, Gilson R, Sullivan AK, Clarke A, Reeves I, Schembri G, Mackie N, Bowman C, Lacey CJ, Apea V, Brady M, Fox J, Taylor S, Antonucci S, Khoo SH, Rooney J, Nardone A, Fisher M, McOwan A, Phillips AN, Johnson AM, Gazzard B, Gill ON.

Lancet. 2016 Jan 2;387(10013):53-60. doi: 10.1016/S0140-6736(15)00056-2. Epub 2015 Sep 9.


Dental amalgam fillings and Helicobacter pylori eradication rates: wide-ranging implications.

Rooney JP, Frissen MN, Bass GA, Dórea JG.

Eur J Gastroenterol Hepatol. 2015 Oct;27(10):1231. doi: 10.1097/MEG.0000000000000446. No abstract available.


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