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Items: 32


Proof of region-specific multipotent progenitors in human breast epithelia.

Fridriksdottir AJ, Villadsen R, Morsing M, Klitgaard MC, Kim J, Petersen OW, Rønnov-Jessen L.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10102-E10111. doi: 10.1073/pnas.1714063114. Epub 2017 Nov 6.


Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.

Hopkinson BM, Klitgaard MC, Petersen OW, Villadsen R, Rønnov-Jessen L, Kim J.

Oncotarget. 2017 Feb 7;8(6):10580-10593. doi: 10.18632/oncotarget.14554.


Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.

Morsing M, Klitgaard MC, Jafari A, Villadsen R, Kassem M, Petersen OW, Rønnov-Jessen L.

Breast Cancer Res. 2016 Nov 3;18(1):108.


Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture.

Fridriksdottir AJ, Kim J, Villadsen R, Klitgaard MC, Hopkinson BM, Petersen OW, Rønnov-Jessen L.

Nat Commun. 2015 Nov 13;6:8786. doi: 10.1038/ncomms9786.


Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.

Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6124-9. doi: 10.1073/pnas.1203203109. Epub 2012 Mar 27.


Mammary gland stem cells: current status and future challenges.

Fridriksdottir AJ, Petersen OW, Rønnov-Jessen L.

Int J Dev Biol. 2011;55(7-9):719-29. doi: 10.1387/ijdb.113373af. Review.


The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.

Lauritzen G, Stock CM, Lemaire J, Lund SF, Jensen MF, Damsgaard B, Petersen KS, Wiwel M, Rønnov-Jessen L, Schwab A, Pedersen SF.

Cancer Lett. 2012 Apr 28;317(2):172-83. doi: 10.1016/j.canlet.2011.11.023. Epub 2011 Nov 25.


Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment.

de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L.

Am J Pathol. 2010 Mar;176(3):1229-40. doi: 10.2353/ajpath.2010.090648. Epub 2010 Feb 4.


Breast cancer by proxy: can the microenvironment be both the cause and consequence?

Rønnov-Jessen L, Bissell MJ.

Trends Mol Med. 2009 Jan;15(1):5-13. doi: 10.1016/j.molmed.2008.11.001. Epub 2008 Dec 16.


Evidence for a stem cell hierarchy in the adult human breast.

Villadsen R, Fridriksdottir AJ, Rønnov-Jessen L, Gudjonsson T, Rank F, LaBarge MA, Bissell MJ, Petersen OW.

J Cell Biol. 2007 Apr 9;177(1):87-101.


Immortalization protocols used in cell culture models of human breast morphogenesis.

Gudjonsson T, Villadsen R, Rønnov-Jessen L, Petersen OW.

Cell Mol Life Sci. 2004 Oct;61(19-20):2523-34. Review.


Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia.

Petersen OW, Gudjonsson T, Villadsen R, Bissell MJ, Rønnov-Jessen L.

Cell Prolif. 2003 Oct;36 Suppl 1:33-44. Review.


Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression.

Nielsen HL, Gudjonsson T, Villadsen R, Rønnov-Jessen L, Petersen OW.

In Vitro Cell Dev Biol Anim. 2003 Jul-Aug;39(7):297-303.


To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia.

Gudjonsson T, Rønnov-Jessen L, Villadsen R, Bissell MJ, Petersen OW.

Methods. 2003 Jul;30(3):247-55.


Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma.

Petersen OW, Nielsen HL, Gudjonsson T, Villadsen R, Rank F, Niebuhr E, Bissell MJ, Rønnov-Jessen L.

Am J Pathol. 2003 Feb;162(2):391-402.


Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer.

Nielsen HL, Rønnov-Jessen L, Villadsen R, Petersen OW.

Genomics. 2002 May;79(5):703-10.


Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties.

Gudjonsson T, Villadsen R, Nielsen HL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Genes Dev. 2002 Mar 15;16(6):693-706.


Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition.

Gudjonsson T, Rønnov-Jessen L, Villadsen R, Rank F, Bissell MJ, Petersen OW.

J Cell Sci. 2002 Jan 1;115(Pt 1):39-50.


The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion.

Petersen OW, Lind Nielsen H, Gudjonsson T, Villadsen R, Rønnov-Jessen L, Bissell MJ.

Breast Cancer Res. 2001;3(4):213-7. Epub 2001 Jun 12. Review.


Human mammary luminal epithelial cells contain progenitors to myoepithelial cells.

Péchoux C, Gudjonsson T, Ronnov-Jessen L, Bissell MJ, Petersen OW.

Dev Biol. 1999 Feb 1;206(1):88-99.


Differentiation and cancer in the mammary gland: shedding light on an old dichotomy.

Petersen OW, Rønnov-Jessen L, Weaver VM, Bissell MJ.

Adv Cancer Res. 1998;75:135-61. Review.


Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction.

Rønnov-Jessen L, Petersen OW, Bissell MJ.

Physiol Rev. 1996 Jan;76(1):69-125. Review.


Effects of lymphocytes and fibroblasts on the growth of human mammary carcinoma cells studied in short-term primary cultures.

Ogmundsdóttir HM, Pétursdóttir I, Gudmundsdóttir I, Amundadóttir L, Rønnov-Jessen L, Petersen OW.

In Vitro Cell Dev Biol Anim. 1993 Dec;29A(12):936-42.


Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

Petersen OW, Rønnov-Jessen L, Howlett AR, Bissell MJ.

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):9064-8. Erratum in: Proc Natl Acad Sci U S A 1993 Mar 15;90(6):2556.


Identification, paracrine generation, and possible function of human breast carcinoma myofibroblasts in culture.

Rønnov-Jessen L, Van Deurs B, Nielsen M, Petersen OW.

In Vitro Cell Dev Biol. 1992 Apr;28A(4):273-83.


A fibroblast-associated antigen: characterization in fibroblasts and immunoreactivity in smooth muscle differentiated stromal cells.

Rønnov-Jessen L, Celis JE, Van Deurs B, Petersen OW.

J Histochem Cytochem. 1992 Apr;40(4):475-86.


Smooth muscle differentiation in cultured human breast gland stromal cells.

Rønnov-Jessen L, van Deurs B, Celis JE, Petersen OW.

Lab Invest. 1990 Oct;63(4):532-43.


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