Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54

1.

Prenatal stress and child development: A scoping review of research in low- and middle-income countries.

Buffa G, Dahan S, Sinclair I, St-Pierre M, Roofigari N, Mutran D, Rondeau JJ, Dancause KN.

PLoS One. 2018 Dec 28;13(12):e0207235. doi: 10.1371/journal.pone.0207235. eCollection 2018.

2.

The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.

Neumann U, Ufer M, Jacobson LH, Rouzade-Dominguez ML, Huledal G, Kolly C, Lüönd RM, Machauer R, Veenstra SJ, Hurth K, Rueeger H, Tintelnot-Blomley M, Staufenbiel M, Shimshek DR, Perrot L, Frieauff W, Dubost V, Schiller H, Vogg B, Beltz K, Avrameas A, Kretz S, Pezous N, Rondeau JM, Beckmann N, Hartmann A, Vormfelde S, David OJ, Galli B, Ramos R, Graf A, Lopez Lopez C.

EMBO Mol Med. 2018 Nov;10(11). pii: e9316. doi: 10.15252/emmm.201809316.

3.

Discovery of amino-1,4-oxazines as potent BACE-1 inhibitors.

Veenstra SJ, Rueeger H, Voegtle M, Lueoend R, Holzer P, Hurth K, Tintelnot-Blomley M, Frederiksen M, Rondeau JM, Jacobson L, Staufenbiel M, Neumann U, Machauer R.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2195-2200. doi: 10.1016/j.bmcl.2018.05.003. Epub 2018 May 3.

PMID:
29764741
4.

At-home and in-group delivery of constraint-induced movement therapy in children with hemiparesis: A systematic review.

Durand E, Plante P, Pelletier AA, Rondeau J, Simard F, Voisin J.

Ann Phys Rehabil Med. 2018 Jul;61(4):245-261. doi: 10.1016/j.rehab.2017.10.004. Epub 2017 Nov 11. Review.

PMID:
29132970
5.

Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.

Morvan F, Rondeau JM, Zou C, Minetti G, Scheufler C, Scharenberg M, Jacobi C, Brebbia P, Ritter V, Toussaint G, Koelbing C, Leber X, Schilb A, Witte F, Lehmann S, Koch E, Geisse S, Glass DJ, Lach-Trifilieff E.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12448-12453. doi: 10.1073/pnas.1707925114. Epub 2017 Nov 6.

6.

The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties.

Goepfert A, Lehmann S, Wirth E, Rondeau JM.

Sci Rep. 2017 Aug 21;7(1):8906. doi: 10.1038/s41598-017-08360-9.

7.

Validation of noninvasive hemoglobin measurements using co-oximetry in anesthetized dogs.

Read MR, Rondeau J, Kwong GP.

Can Vet J. 2016 Nov;57(11):1161-1165.

8.

A General Strategy for Targeting Drugs to Bone.

Jahnke W, Bold G, Marzinzik AL, Ofner S, Pellé X, Cotesta S, Bourgier E, Lehmann S, Henry C, Hemmig R, Stauffer F, Hartwieg JC, Green JR, Rondeau JM.

Angew Chem Int Ed Engl. 2015 Nov 23;54(48):14575-9. doi: 10.1002/anie.201507064. Epub 2015 Oct 12.

PMID:
26457482
9.

Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.

Marzinzik AL, Amstutz R, Bold G, Bourgier E, Cotesta S, Glickman JF, Götte M, Henry C, Lehmann S, Hartwieg JC, Ofner S, Pellé X, Roddy TP, Rondeau JM, Stauffer F, Stout SJ, Widmer A, Zimmermann J, Zoller T, Jahnke W.

ChemMedChem. 2015 Nov;10(11):1884-91. doi: 10.1002/cmdc.201500338. Epub 2015 Sep 18.

PMID:
26381451
10.

The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β.

Rondeau JM, Ramage P, Zurini M, Gram H.

MAbs. 2015;7(6):1151-60. doi: 10.1080/19420862.2015.1081323. Epub 2015 Aug 18.

11.

SEC-TID: A Label-Free Method for Small-Molecule Target Identification.

Salcius M, Bauer AJ, Hao Q, Li S, Tutter A, Raphael J, Jahnke W, Rondeau JM, Bourgier E, Tallarico J, Michaud GA.

J Biomol Screen. 2014 Jul;19(6):917-27. doi: 10.1177/1087057114522691. Epub 2014 Feb 19.

PMID:
24554445
12.

Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid β-peptides.

Rueeger H, Lueoend R, Machauer R, Veenstra SJ, Jacobson LH, Staufenbiel M, Desrayaud S, Rondeau JM, Möbitz H, Neumann U.

Bioorg Med Chem Lett. 2013 Oct 1;23(19):5300-6. doi: 10.1016/j.bmcl.2013.07.071. Epub 2013 Aug 9.

PMID:
23981898
13.

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling.

Cai X, Xu Y, Cheung AK, Tomlinson RC, Alcázar-Román A, Murphy L, Billich A, Zhang B, Feng Y, Klumpp M, Rondeau JM, Fazal AN, Wilson CJ, Myer V, Joberty G, Bouwmeester T, Labow MA, Finan PM, Porter JA, Ploegh HL, Baird D, De Camilli P, Tallarico JA, Huang Q.

Chem Biol. 2013 Jul 25;20(7):912-21. doi: 10.1016/j.chembiol.2013.05.010.

14.

Protein crystallization in stirred systems--scale-up via the maximum local energy dissipation.

Smejkal B, Helk B, Rondeau JM, Anton S, Wilke A, Scheyerer P, Fries J, Hekmat D, Weuster-Botz D.

Biotechnol Bioeng. 2013 Jul;110(7):1956-63. doi: 10.1002/bit.24845. Epub 2013 Feb 9.

PMID:
23335375
15.

Discovery of cyclic sulfone hydroxyethylamines as potent and selective β-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure-based design and in vivo reduction of amyloid β-peptides.

Rueeger H, Lueoend R, Rogel O, Rondeau JM, Möbitz H, Machauer R, Jacobson L, Staufenbiel M, Desrayaud S, Neumann U.

J Med Chem. 2012 Apr 12;55(7):3364-86. doi: 10.1021/jm300069y. Epub 2012 Mar 21.

PMID:
22380629
16.

Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors.

Rueeger H, Rondeau JM, McCarthy C, Möbitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S.

Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. doi: 10.1016/j.bmcl.2011.02.038. Epub 2011 Feb 15.

PMID:
21388807
17.

Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.

Jahnke W, Rondeau JM, Cotesta S, Marzinzik A, Pellé X, Geiser M, Strauss A, Götte M, Bitsch F, Hemmig R, Henry C, Lehmann S, Glickman JF, Roddy TP, Stout SJ, Green JR.

Nat Chem Biol. 2010 Sep;6(9):660-6. doi: 10.1038/nchembio.421. Epub 2010 Aug 15.

PMID:
20711197
18.

Structure-based design and synthesis of novel P2/P3 modified, non-peptidic beta-secretase (BACE-1) inhibitors.

Hanessian S, Shao Z, Betschart C, Rondeau JM, Neumann U, Tintelnot-Blomley M.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):1924-7. doi: 10.1016/j.bmcl.2010.01.139. Epub 2010 Feb 2. Erratum in: Bioorg Med Chem Lett. 2013 Apr 15;23(8):2460-1.

PMID:
20172717
19.

Macrocyclic BACE-1 inhibitors acutely reduce Abeta in brain after po application.

Lerchner A, Machauer R, Betschart C, Veenstra S, Rueeger H, McCarthy C, Tintelnot-Blomley M, Jaton AL, Rabe S, Desrayaud S, Enz A, Staufenbiel M, Paganetti P, Rondeau JM, Neumann U.

Bioorg Med Chem Lett. 2010 Jan 15;20(2):603-7. doi: 10.1016/j.bmcl.2009.11.092. Epub 2009 Nov 22.

PMID:
19963375
20.

Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo.

Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. doi: 10.1016/j.bmcl.2009.01.055. Epub 2009 Jan 22.

PMID:
19195887
21.

Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors.

Machauer R, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Neumann U, Paganetti P.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1361-5. doi: 10.1016/j.bmcl.2009.01.036. Epub 2009 Jan 19. Erratum in: Bioorg Med Chem Lett. 2009 Apr 15;19(8):2366.

PMID:
19195886
22.

Conformationally constrained mimics of the membrane-proximal domain of Fc epsilonRIalpha.

Peters C, Bacher M, Buenemann CL, Kricek F, Rondeau JM, Weigand K.

Chembiochem. 2007 Oct 15;8(15):1785-9. No abstract available.

PMID:
17828717
23.

Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.

Rondeau JM, Bitsch F, Bourgier E, Geiser M, Hemmig R, Kroemer M, Lehmann S, Ramage P, Rieffel S, Strauss A, Green JR, Jahnke W.

ChemMedChem. 2006 Feb;1(2):267-73.

PMID:
16892359
24.

Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE).

Hanessian S, Yang G, Rondeau JM, Neumann U, Betschart C, Tintelnot-Blomley M.

J Med Chem. 2006 Jul 27;49(15):4544-67.

PMID:
16854060
25.

Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics.

Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C.

J Med Chem. 2005 Aug 11;48(16):5175-90.

PMID:
16078837
26.

Structure-based design and protein X-ray analysis of a protein kinase inhibitor.

Furet P, Meyer T, Strauss A, Raccuglia S, Rondeau JM.

Bioorg Med Chem Lett. 2002 Jan 21;12(2):221-4.

PMID:
11755359
27.

Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).

Ettmayer P, France D, Gounarides J, Jarosinski M, Martin MS, Rondeau JM, Sabio M, Topiol S, Weidmann B, Zurini M, Bair KW.

J Med Chem. 1999 Mar 25;42(6):971-80.

PMID:
10090780
28.

Monoaryl- and bisaryldihydroxytropolones as potent inhibitors of inositol monophosphatase.

Piettre SR, André C, Chanal MC, Ducep JB, Lesur B, Piriou F, Raboisson P, Rondeau JM, Schelcher C, Zimmermann P, Ganzhorn AJ.

J Med Chem. 1997 Dec 19;40(26):4208-21.

PMID:
9435892
29.

Combined tubal and cornual pregnancy in a patient without risk factors. A case report.

Rondeau JA, Hibbert ML, Nelson KM.

J Reprod Med. 1997 Oct;42(10):675-7.

PMID:
9350026
30.

Radioimmunoassay of meterelin and pharmacokinetics after single injection and implant administration in dogs.

Hudon E, Rondeau JJ, Lenaerts V, Würthrich P, Boutignon F, Deghenghi R, Marleau S, Yamaguchi N, Adam A, Ong H.

J Pharm Sci. 1997 Feb;86(2):172-8.

PMID:
9040091
31.

Localization by photoaffinity labeling of natriuretic peptide receptor-A binding domain.

McNicoll N, Gagnon J, Rondeau JJ, Ong H, De Léan A.

Biochemistry. 1996 Oct 1;35(39):12950-6.

PMID:
8841141
32.

The contribution of lysine-36 to catalysis by human myo-inositol monophosphatase.

Ganzhorn AJ, Lepage P, Pelton PD, Strasser F, Vincendon P, Rondeau JM.

Biochemistry. 1996 Aug 20;35(33):10957-66.

PMID:
8718889
33.

Radioimmunoassay of Antarelix, a luteinizing hormone releasing-hormone antagonist, in plasma and its application for pharmacokinetic study in dogs.

Sorensen S, Rondeau JJ, Lenaerts V, Boutignon F, Wüthrich P, Deghenghi R, Adam A, Ong H.

J Immunoassay. 1996 Aug;17(3):205-26.

PMID:
8842981
34.

Stoichiometry of the atrial natriuretic factor-R1 receptor complex in the bovine zona glomerulosa.

Rondeau JJ, McNicoll N, Gagnon J, Bouchard N, Ong H, De Léan A.

Biochemistry. 1995 Feb 21;34(7):2130-6.

PMID:
7857923
35.

Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.

Schreuder HA, Rondeau JM, Tardif C, Soffientini A, Sarubbi E, Akeson A, Bowlin TL, Yanofsky S, Barrett RW.

Eur J Biochem. 1995 Feb 1;227(3):838-47.

36.

Crystal structure of Aeromonas proteolytica aminopeptidase: a prototypical member of the co-catalytic zinc enzyme family.

Chevrier B, Schalk C, D'Orchymont H, Rondeau JM, Moras D, Tarnus C.

Structure. 1994 Apr 15;2(4):283-91.

PMID:
8087555
37.

Structure determination of aldose reductase: joys and traps of local symmetry averaging.

Tête-Favier F, Rondeau JM, Podjarny A, Moras D.

Acta Crystallogr D Biol Crystallogr. 1993 Mar 1;49(Pt 2):246-56.

PMID:
15299530
38.

Plant nurseries: a reliable resource for plant identification?

Rondeau ES, Everson GW, Savage W, Rondeau JH.

Vet Hum Toxicol. 1992 Dec;34(6):544-6.

PMID:
1287976
39.

Phosphorylation of atrial natriuretic factor R1 receptor by serine/threonine protein kinases: evidences for receptor regulation.

Larose L, Rondeau JJ, Ong H, De Léan A.

Mol Cell Biochem. 1992 Oct 7;115(2):203-11.

PMID:
1280321
40.

Purification and electrospray mass spectrometry of aldose reductase from pig lens.

Reymann JM, Rondeau JM, Barth P, Jaquinod M, Van Dorsselaer A, Biellmann JF.

Biochim Biophys Acta. 1992 Jul 13;1122(1):1-5.

PMID:
1633191
41.

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase.

Rondeau JM, Tête-Favier F, Podjarny A, Reymann JM, Barth P, Biellmann JF, Moras D.

Nature. 1992 Jan 30;355(6359):469-72.

PMID:
1734286
42.

Production of polyclonal antibody to the bovine adrenal atrial natriuretic factor-R1 receptor.

Rondeau JJ, McNicoll N, Lord C, Larose L, Meloche S, Gagnon J, Ong H, De Léan A.

J Recept Res. 1992;12(4):485-505.

PMID:
1281231
43.

Structural studies of pig lens aldose reductase: reversible dimerization of the enzyme.

Rondeau JM, Moras D, Tête F, Podjarny A, Van Dorsselaer A, Reymann JM, Barth P, Biellmann JF.

Adv Exp Med Biol. 1991;284:113-8. No abstract available.

PMID:
1905095
44.

Hydrodynamic properties of the angiotensin II receptor from bovine adrenal zona glomerulosa.

Rondeau JJ, McNicoll N, Escher E, Meloche S, Ong H, De Léan A.

Biochem J. 1990 Jun 1;268(2):443-8.

45.
46.

Comparisons between patients' and nurses' assessment of pain and medication efficacy in severe burn injuries.

Choinière M, Melzack R, Girard N, Rondeau J, Paquin MJ.

Pain. 1990 Feb;40(2):143-52.

PMID:
2308761
47.

The pain of burns: characteristics and correlates.

Choinière M, Melzack R, Rondeau J, Girard N, Paquin MJ.

J Trauma. 1989 Nov;29(11):1531-9.

PMID:
2585565
48.

Crystallization and preliminary X-ray data of a phleomycin-binding protein from Streptoalloteichus hindustanus.

Rondeau JM, Cagnon C, Moras D, Masson JM.

J Mol Biol. 1989 Jun 5;207(3):645-6.

PMID:
2474660
49.

Determination of opiates and other basic drugs by high-performance liquid chromatography with electrochemical detection.

Besner JG, Band C, Rondeau JJ, Yamlahi L, Caillé G, Varin F, Stewart J.

J Pharm Biomed Anal. 1989;7(12):1811-7.

PMID:
2490569
50.

Crystallization and preliminary X-ray study of pig lens aldose reductase.

Rondeau JM, Samama JP, Samama B, Barth P, Moras D, Biellmann JF.

J Mol Biol. 1987 Jun 20;195(4):945-8.

PMID:
3116267

Supplemental Content

Loading ...
Support Center