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Items: 1 to 50 of 87

1.

Human iPSC modeling of a familial form of atrial fibrillation reveals a gain of function of If and ICaL in patient-derived cardiomyocytes.

Benzoni P, Campostrini G, Landi S, Bertini V, Marchina E, Iascone M, Ahlberg G, Olesen MS, Crescini E, Mora C, Bisleri G, Muneretto C, Ronca R, Presta M, Poliani PL, Piovani G, Verardi R, Pasquale ED, Consiglio A, Raya A, Torre E, Lodrini AM, Milanesi R, Rocchetti M, Baruscotti M, DiFrancesco D, Memo M, Barbuti A, Dell'Era P.

Cardiovasc Res. 2019 Aug 28. pii: cvz217. doi: 10.1093/cvr/cvz217. [Epub ahead of print]

PMID:
31504264
2.

The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach.

Rezzola S, Ronca R, Loda A, Nawaz MI, Tobia C, Paganini G, Maccarinelli F, Giacomini A, Semeraro F, Mor M, Presta M.

Cancers (Basel). 2019 Sep 4;11(9). pii: E1305. doi: 10.3390/cancers11091305.

3.

Long Pentraxin-3 Follows and Modulates Bladder Cancer Progression.

Matarazzo S, Melocchi L, Rezzola S, Grillo E, Maccarinelli F, Giacomini A, Turati M, Taranto S, Zammataro L, Cerasuolo M, Bugatti M, Vermi W, Presta M, Ronca R.

Cancers (Basel). 2019 Aug 30;11(9). pii: E1277. doi: 10.3390/cancers11091277.

4.

Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome.

Gatta LB, Melocchi L, Bugatti M, Missale F, Lonardi S, Zanetti B, Cristinelli L, Belotti S, Simeone C, Ronca R, Grillo E, Licini S, Bresciani D, Tardanico R, Chan SR, Giurisato E, Calza S, Vermi W.

Cancers (Basel). 2019 Aug 21;11(9). pii: E1219. doi: 10.3390/cancers11091219.

5.

Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.

Romagnoli R, Oliva P, Salvador MK, Camacho ME, Padroni C, Brancale A, Ferla S, Hamel E, Ronca R, Grillo E, Bortolozzi R, Rruga F, Mariotto E, Viola G.

Eur J Med Chem. 2019 Aug 1;181:111577. doi: 10.1016/j.ejmech.2019.111577. [Epub ahead of print]

PMID:
31400707
6.

Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones.

Bortolozzi R, Carta D, Prà MD, Antoniazzi G, Mattiuzzo E, Sturlese M, Di Paolo V, Calderan L, Moro S, Hamel E, Quintieri L, Ronca R, Viola G, Ferlin MG.

Eur J Med Chem. 2019 Sep 15;178:297-314. doi: 10.1016/j.ejmech.2019.05.092. Epub 2019 Jun 3.

PMID:
31195171
7.

Circulating microRNAs and Their Role in Multiple Myeloma.

Federico C, Sacco A, Belotti A, Ribolla R, Cancelli V, Giacomini A, Ronca R, Chiarini M, Imberti L, Marini M, Rossi G, Presta M, Paiva B, Roccaro AM.

Noncoding RNA. 2019 May 2;5(2). pii: E37. doi: 10.3390/ncrna5020037. Review.

8.

Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents.

Morigi R, Locatelli A, Leoni A, Rambaldi M, Bortolozzi R, Mattiuzzo E, Ronca R, Maccarinelli F, Hamel E, Bai R, Brancale A, Viola G.

Eur J Med Chem. 2019 Mar 15;166:514-530. doi: 10.1016/j.ejmech.2019.01.049. Epub 2019 Jan 26.

PMID:
30784885
9.

Caveolin-1 enhances metastasis formation in a human model of embryonal rhabdomyosarcoma through Erk signaling cooperation.

Codenotti S, Faggi F, Ronca R, Chiodelli P, Grillo E, Guescini M, Megiorni F, Marampon F, Fanzani A.

Cancer Lett. 2019 May 1;449:135-144. doi: 10.1016/j.canlet.2019.02.013. Epub 2019 Feb 13.

PMID:
30771426
10.

Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway.

Vrijens P, Noppen S, Boogaerts T, Vanstreels E, Ronca R, Chiodelli P, Laporte M, Vanderlinden E, Liekens S, Stevaert A, Naesens L.

J Gen Virol. 2019 Apr;100(4):583-601. doi: 10.1099/jgv.0.001235. Epub 2019 Feb 14.

PMID:
30762518
11.

Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors.

Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Schiaffino Ortega S, Chayah M, Kimatrai Salvador M, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Mattiuzzo E, Viola G.

J Med Chem. 2019 Feb 14;62(3):1274-1290. doi: 10.1021/acs.jmedchem.8b01391. Epub 2019 Jan 18.

PMID:
30633509
12.

Long Pentraxin 3-Mediated Fibroblast Growth Factor Trapping Impairs Fibrosarcoma Growth.

Rodrigues PF, Matarazzo S, Maccarinelli F, Foglio E, Giacomini A, Silva Nunes JP, Presta M, Dias AAM, Ronca R.

Front Oncol. 2018 Nov 1;8:472. doi: 10.3389/fonc.2018.00472. eCollection 2018.

13.

Choline Kinase Alpha Inhibition by EB-3D Triggers Cellular Senescence, Reduces Tumor Growth and Metastatic Dissemination in Breast Cancer.

Mariotto E, Viola G, Ronca R, Persano L, Aveic S, Bhujwalla ZM, Mori N, Accordi B, Serafin V, López-Cara LC, Bortolozzi R.

Cancers (Basel). 2018 Oct 22;10(10). pii: E391. doi: 10.3390/cancers10100391.

14.

Long Pentraxin-3 Modulates the Angiogenic Activity of Fibroblast Growth Factor-2.

Presta M, Foglio E, Churruca Schuind A, Ronca R.

Front Immunol. 2018 Oct 8;9:2327. doi: 10.3389/fimmu.2018.02327. eCollection 2018. Review.

15.

Improvement and extension of anti-EGFR targeting in breast cancer therapy by integration with the Avidin-Nucleic-Acid-Nano-Assemblies.

Roncato F, Rruga F, Porcù E, Casarin E, Ronca R, Maccarinelli F, Realdon N, Basso G, Alon R, Viola G, Morpurgo M.

Nat Commun. 2018 Oct 4;9(1):4070. doi: 10.1038/s41467-018-06602-6.

16.

Future applications of FGF/FGFR inhibitors in cancer.

Ghedini GC, Ronca R, Presta M, Giacomini A.

Expert Rev Anticancer Ther. 2018 Sep;18(9):861-872. doi: 10.1080/14737140.2018.1491795. Epub 2018 Jul 2. Review.

PMID:
29936878
17.

Dendritic cells in inflammatory angiogenesis and lymphangiogenesis.

Bosisio D, Ronca R, Salvi V, Presta M, Sozzani S.

Curr Opin Immunol. 2018 Aug;53:180-186. doi: 10.1016/j.coi.2018.05.011. Epub 2018 Jun 4. Review.

PMID:
29879585
18.

Uptake Profiles of Human Serum Exosomes by Murine and Human Tumor Cells through Combined Use of Colloidal Nanoplasmonics and Flow Cytofluorimetric Analysis.

Busatto S, Giacomini A, Montis C, Ronca R, Bergese P.

Anal Chem. 2018 Jul 3;90(13):7855-7861. doi: 10.1021/acs.analchem.7b04374. Epub 2018 Jun 15.

PMID:
29870225
19.

Biochemical characterization of a thermostable endomannanase/endoglucanase from Dictyoglomus turgidum.

Fusco FA, Ronca R, Fiorentino G, Pedone E, Contursi P, Bartolucci S, Limauro D.

Extremophiles. 2018 Jan;22(1):131-140. doi: 10.1007/s00792-017-0983-6. Epub 2017 Nov 25.

PMID:
29177717
20.

Long pentraxin 3: A novel multifaceted player in cancer.

Giacomini A, Ghedini GC, Presta M, Ronca R.

Biochim Biophys Acta Rev Cancer. 2018 Jan;1869(1):53-63. doi: 10.1016/j.bbcan.2017.11.004. Epub 2017 Nov 23. Review.

PMID:
29175552
21.

Specific Effects of Chronic Dietary Exposure to Chlorpyrifos on Brain Gene Expression-A Mouse Study.

Pallotta MM, Ronca R, Carotenuto R, Porreca I, Turano M, Ambrosino C, Capriglione T.

Int J Mol Sci. 2017 Nov 20;18(11). pii: E2467. doi: 10.3390/ijms18112467.

22.

Fibroblast growth factor modulates mast cell recruitment in a murine model of prostate cancer.

Ronca R, Tamma R, Coltrini D, Ruggieri S, Presta M, Ribatti D.

Oncotarget. 2017 Aug 1;8(47):82583-82592. doi: 10.18632/oncotarget.19773. eCollection 2017 Oct 10.

23.

Utilizing CT with Maximum Intensity Projection Reconstruction Bypassing CTA Improves Time to Groin Puncture in Large Vessel Occlusion Stroke Thrombectomy.

Atchaneeyasakul K, Tipirneni A, Khandelwal P, Saini V, Ronca R, Lord S, Sur S, Guada L, Ramdas K, Peterson E, Yavagal D.

Interv Neurol. 2017 Oct;6(3-4):147-152. doi: 10.1159/000464300. Epub 2017 Mar 29.

24.

Paracrine interactions of cancer-associated fibroblasts, macrophages and endothelial cells: tumor allies and foes.

Ronca R, Van Ginderachter JA, Turtoi A.

Curr Opin Oncol. 2018 Jan;30(1):45-53. doi: 10.1097/CCO.0000000000000420. Review.

PMID:
29084000
25.

Contribution of vascular endothelial growth factor receptor-2 sialylation to the process of angiogenesis.

Chiodelli P, Rezzola S, Urbinati C, Federici Signori F, Monti E, Ronca R, Presta M, Rusnati M.

Oncogene. 2017 Nov 23;36(47):6531-6541. doi: 10.1038/onc.2017.243. Epub 2017 Aug 7.

PMID:
28783175
26.

Tumor angiogenesis revisited: Regulators and clinical implications.

Ronca R, Benkheil M, Mitola S, Struyf S, Liekens S.

Med Res Rev. 2017 Nov;37(6):1231-1274. doi: 10.1002/med.21452. Epub 2017 Jun 23. Review.

PMID:
28643862
27.

Functional analyses yield detailed insight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae.

Pirone L, Ripoll-Rozada J, Leone M, Ronca R, Lombardo F, Fiorentino G, Andersen JF, Pereira PJB, Arcà B, Pedone E.

J Biol Chem. 2017 Jul 28;292(30):12632-12642. doi: 10.1074/jbc.M117.788042. Epub 2017 Jun 7.

28.

Fibroblast growth factors (FGFs) in cancer: FGF traps as a new therapeutic approach.

Presta M, Chiodelli P, Giacomini A, Rusnati M, Ronca R.

Pharmacol Ther. 2017 Nov;179:171-187. doi: 10.1016/j.pharmthera.2017.05.013. Epub 2017 May 28. Review.

PMID:
28564583
29.

U94 of human herpesvirus 6 down-modulates Src, promotes a partial mesenchymal-to-epithelial transition and inhibits tumor cell growth, invasion and metastasis.

Caccuri F, Ronca R, Laimbacher AS, Berenzi A, Steimberg N, Campilongo F, Mazzuca P, Giacomini A, Mazzoleni G, Benetti A, Caselli E, Presta M, Di Luca D, Fraefel C, Caruso A.

Oncotarget. 2017 Jul 4;8(27):44533-44549. doi: 10.18632/oncotarget.17817.

30.

Eukaryotic initiation factor eIF6 modulates the expression of Kermit 2/XGIPC in IGF- regulated eye development.

De Marco N, Tussellino M, Carotenuto R, Ronca R, Rizzolio S, Biffo S, Campanella C.

Dev Biol. 2017 Jul 1;427(1):148-154. doi: 10.1016/j.ydbio.2017.04.017. Epub 2017 May 1.

31.

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Salvador MK, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Porcù E, Basso G, Viola G.

Sci Rep. 2017 Apr 13;7:46356. doi: 10.1038/srep46356.

32.

Brain Gene Expression is Influenced by Incubation Temperature During Leopard Gecko (Eublepharis macularius) Development.

Pallotta MM, Turano M, Ronca R, Mezzasalma M, Petraccioli A, Odierna G, Capriglione T.

J Exp Zool B Mol Dev Evol. 2017 Jun;328(4):360-370. doi: 10.1002/jez.b.22736. Epub 2017 Mar 20.

PMID:
28317246
33.

Inflammation and N-formyl peptide receptors mediate the angiogenic activity of human vitreous humour in proliferative diabetic retinopathy.

Rezzola S, Corsini M, Chiodelli P, Cancarini A, Nawaz IM, Coltrini D, Mitola S, Ronca R, Belleri M, Lista L, Rusciano D, De Rosa M, Pavone V, Semeraro F, Presta M.

Diabetologia. 2017 Apr;60(4):719-728. doi: 10.1007/s00125-016-4204-0. Epub 2017 Jan 13.

PMID:
28083635
34.

Chlorpyrifos exposure affects fgf8, sox9, and bmp4 expression required for cranial neural crest morphogenesis and chondrogenesis in Xenopus laevis embryos.

Tussellino M, Ronca R, Carotenuto R, Pallotta MM, Furia M, Capriglione T.

Environ Mol Mutagen. 2016 Oct;57(8):630-640. doi: 10.1002/em.22057. Epub 2016 Sep 27.

PMID:
27669663
35.

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.

Porcù E, Persano L, Ronca R, Mitola S, Bortolozzi R, Romagnoli R, Oliva P, Basso G, Viola G.

Sci Rep. 2016 Jun 13;6:27886. doi: 10.1038/srep27886.

36.

Vascular disrupting activity of combretastatin analogues.

Porcù E, Salvador A, Primac I, Mitola S, Ronca R, Ravelli C, Bortolozzi R, Vedaldi D, Romagnoli R, Basso G, Viola G.

Vascul Pharmacol. 2016 Aug;83:78-89. doi: 10.1016/j.vph.2016.05.006. Epub 2016 May 25.

PMID:
27235861
37.

Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3',4',5'-Trimethoxyphenyl)-2-Aryl-1H-Imidazole.

Romagnoli R, Baraldi PG, Prencipe F, Oliva P, Baraldi S, Tabrizi MA, Lopez-Cara LC, Ferla S, Brancale A, Hamel E, Ronca R, Bortolozzi R, Mariotto E, Basso G, Viola G.

Sci Rep. 2016 May 24;6:26602. doi: 10.1038/srep26602.

38.

Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist.

Grillo E, Ravelli C, Corsini M, Ballmer-Hofer K, Zammataro L, Oreste P, Zoppetti G, Tobia C, Ronca R, Presta M, Mitola S.

Oncotarget. 2016 Jun 7;7(23):35353-68. doi: 10.18632/oncotarget.9286.

39.

Synthesis, Structural Elucidation, and Biological Evaluation of NSC12, an Orally Available Fibroblast Growth Factor (FGF) Ligand Trap for the Treatment of FGF-Dependent Lung Tumors.

Castelli R, Giacomini A, Anselmi M, Bozza N, Vacondio F, Rivara S, Matarazzo S, Presta M, Mor M, Ronca R.

J Med Chem. 2016 May 26;59(10):4651-63. doi: 10.1021/acs.jmedchem.5b02021. Epub 2016 May 3.

PMID:
27138345
40.

Blocking the FGF/FGFR system as a "two-compartment" antiangiogenic/antitumor approach in cancer therapy.

Giacomini A, Chiodelli P, Matarazzo S, Rusnati M, Presta M, Ronca R.

Pharmacol Res. 2016 May;107:172-185. doi: 10.1016/j.phrs.2016.03.024. Epub 2016 Mar 22. Review.

PMID:
27013279
41.

HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies.

Peixoto P, Blomme A, Costanza B, Ronca R, Rezzola S, Palacios AP, Schoysman L, Boutry S, Goffart N, Peulen O, Maris P, Di Valentin E, Hennequière V, Bianchi E, Henry A, Meunier P, Rogister B, Muller RN, Delvenne P, Bellahcène A, Castronovo V, Turtoi A.

Oncogene. 2016 Aug 25;35(34):4481-94. doi: 10.1038/onc.2015.506. Epub 2016 Feb 8.

PMID:
26853466
42.

Antibody acquisition models: A new tool for serological surveillance of malaria transmission intensity.

Yman V, White MT, Rono J, Arcà B, Osier FH, Troye-Blomberg M, Boström S, Ronca R, Rooth I, Färnert A.

Sci Rep. 2016 Feb 5;6:19472. doi: 10.1038/srep19472.

43.

Long-Pentraxin 3 Derivative as a Small-Molecule FGF Trap for Cancer Therapy.

Ronca R, Giacomini A, Di Salle E, Coltrini D, Pagano K, Ragona L, Matarazzo S, Rezzola S, Maiolo D, Torrella R, Moroni E, Mazzieri R, Escobar G, Mor M, Colombo G, Presta M.

Cancer Cell. 2015 Aug 10;28(2):225-39. doi: 10.1016/j.ccell.2015.07.002.

44.

The potential of fibroblast growth factor/fibroblast growth factor receptor signaling as a therapeutic target in tumor angiogenesis.

Ronca R, Giacomini A, Rusnati M, Presta M.

Expert Opin Ther Targets. 2015;19(10):1361-77. doi: 10.1517/14728222.2015.1062475. Epub 2015 Jun 30. Review.

PMID:
26125971
45.

A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice.

Ronca RD, Myers AM, Ganea D, Tuma RF, Walker EA, Ward SJ.

Life Sci. 2015 Oct 1;138:72-7. doi: 10.1016/j.lfs.2015.05.005. Epub 2015 May 30.

46.

A long pentraxin-3-derived pentapeptide for the therapy of FGF8b-driven steroid hormone-regulated cancers.

Giacomini A, Matarazzo S, Pagano K, Ragona L, Rezzola S, Corsini M, Di Salle E, Presta M, Ronca R.

Oncotarget. 2015 May 30;6(15):13790-802.

47.

Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.

Faggi F, Chiarelli N, Colombi M, Mitola S, Ronca R, Madaro L, Bouche M, Poliani PL, Vezzoli M, Longhena F, Monti E, Salani B, Maggi D, Keller C, Fanzani A.

Lab Invest. 2015 Jun;95(6):585-602. doi: 10.1038/labinvest.2015.45. Epub 2015 Mar 30.

48.

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G.

J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26.

49.

The Anopheles gambiae cE5 salivary protein: a sensitive biomarker to evaluate the efficacy of insecticide-treated nets in malaria vector control.

Marie A, Ronca R, Poinsignon A, Lombardo F, Drame PM, Cornelie S, Besnard P, Le Mire J, Fiorentino G, Fortes F, Carnevale P, Remoue F, Arcà B.

Microbes Infect. 2015 Jun;17(6):409-16. doi: 10.1016/j.micinf.2015.01.002. Epub 2015 Jan 28.

PMID:
25637950
50.

The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors.

Liekens S, Noppen S, Gijsbers S, Sienaert R, Ronca R, Tobia C, Presta M.

Oncotarget. 2015 Mar 10;6(7):4633-48.

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