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Items: 2

1.

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A.

Rivero-Ríos P, Romo-Lozano M, Madero-Pérez J, Thomas AP, Biosa A, Greggio E, Hilfiker S.

J Biol Chem. 2019 Mar 29;294(13):4738-4758. doi: 10.1074/jbc.RA118.005008. Epub 2019 Feb 1.

2.

Cellular effects mediated by pathogenic LRRK2: homing in on Rab-mediated processes.

Madero-Pérez J, Fdez E, Fernández B, Lara Ordóñez AJ, Blanca Ramírez M, Romo Lozano M, Rivero-Ríos P, Hilfiker S.

Biochem Soc Trans. 2017 Feb 8;45(1):147-154. doi: 10.1042/BST20160392. Review.

PMID:
28202668

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