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Items: 30


SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.

Hart PC, Chiyoda T, Liu X, Weigert M, Curtis M, Chiang CY, Loth R, Lastra R, McGregor SM, Locasale JW, Lengyel E, Romero IL.

Mol Cancer Res. 2019 Apr;17(4):870-881. doi: 10.1158/1541-7786.MCR-18-0409. Epub 2019 Jan 17.


Intensive Surveillance with Biannual Dynamic Contrast-Enhanced Magnetic Resonance Imaging Downstages Breast Cancer in BRCA1 Mutation Carriers.

Guindalini RSC, Zheng Y, Abe H, Whitaker K, Yoshimatsu TF, Walsh T, Schacht D, Kulkarni K, Sheth D, Verp MS, Bradbury AR, Churpek J, Obeid E, Mueller J, Khramtsova G, Liu F, Raoul A, Cao H, Romero IL, Hong S, Livingston R, Jaskowiak N, Wang X, Debiasi M, Pritchard CC, King MC, Karczmar G, Newstead GM, Huo D, Olopade OI.

Clin Cancer Res. 2019 Mar 15;25(6):1786-1794. doi: 10.1158/1078-0432.CCR-18-0200. Epub 2018 Aug 28.


Lesbian Pregnancy: Care and Considerations.

Bushe S, Romero IL.

Semin Reprod Med. 2017 Sep;35(5):420-425. doi: 10.1055/s-0037-1606385. Epub 2017 Oct 26. Review.


Obstetrics and Gynecology: A Specialty at the Forefront of Care for LGBTQ Patients.

Romero IL.

Semin Reprod Med. 2017 Sep;35(5):395-396. doi: 10.1055/s-0037-1607044. Epub 2017 Oct 26. No abstract available.


Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.

Chiyoda T, Hart PC, Eckert MA, McGregor SM, Lastra RR, Hamamoto R, Nakamura Y, Yamada SD, Olopade OI, Lengyel E, Romero IL.

Cancer Prev Res (Phila). 2017 Apr;10(4):255-266. doi: 10.1158/1940-6207.CAPR-16-0281. Epub 2017 Mar 6.


Metformin Targets Central Carbon Metabolism and Reveals Mitochondrial Requirements in Human Cancers.

Liu X, Romero IL, Litchfield LM, Lengyel E, Locasale JW.

Cell Metab. 2016 Nov 8;24(5):728-739. doi: 10.1016/j.cmet.2016.09.005. Epub 2016 Oct 13.


Association of Metformin Use with Outcomes in Advanced Endometrial Cancer Treated with Chemotherapy.

Ezewuiro O, Grushko TA, Kocherginsky M, Habis M, Hurteau JA, Mills KA, Hunn J, Olopade OI, Fleming GF, Romero IL.

PLoS One. 2016 Jan 20;11(1):e0147145. doi: 10.1371/journal.pone.0147145. eCollection 2016.


Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.

Bowtell DD, Böhm S, Ahmed AA, Aspuria PJ, Bast RC Jr, Beral V, Berek JS, Birrer MJ, Blagden S, Bookman MA, Brenton JD, Chiappinelli KB, Martins FC, Coukos G, Drapkin R, Edmondson R, Fotopoulou C, Gabra H, Galon J, Gourley C, Heong V, Huntsman DG, Iwanicki M, Karlan BY, Kaye A, Lengyel E, Levine DA, Lu KH, McNeish IA, Menon U, Narod SA, Nelson BH, Nephew KP, Pharoah P, Powell DJ Jr, Ramos P, Romero IL, Scott CL, Sood AK, Stronach EA, Balkwill FR.

Nat Rev Cancer. 2015 Nov;15(11):668-79. doi: 10.1038/nrc4019. Review.


Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer.

Litchfield LM, Mukherjee A, Eckert MA, Johnson A, Mills KA, Pan S, Shridhar V, Lengyel E, Romero IL.

Oncotarget. 2015 Sep 15;6(27):23548-60.


Molecular pathways: trafficking of metabolic resources in the tumor microenvironment.

Romero IL, Mukherjee A, Kenny HA, Litchfield LM, Lengyel E.

Clin Cancer Res. 2015 Feb 15;21(4):680-6. doi: 10.1158/1078-0432.CCR-14-2198. Review.


Old drug, new trick: repurposing metformin for gynecologic cancers?

Febbraro T, Lengyel E, Romero IL.

Gynecol Oncol. 2014 Dec;135(3):614-21. doi: 10.1016/j.ygyno.2014.10.011. Epub 2014 Oct 23. Review.


Metformin inhibits ovarian cancer growth and increases sensitivity to paclitaxel in mouse models.

Lengyel E, Litchfield LM, Mitra AK, Nieman KM, Mukherjee A, Zhang Y, Johnson A, Bradaric M, Lee W, Romero IL.

Am J Obstet Gynecol. 2015 Apr;212(4):479.e1-479.e10. doi: 10.1016/j.ajog.2014.10.026. Epub 2014 Oct 19.


Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.

Kenny HA, Chiang CY, White EA, Schryver EM, Habis M, Romero IL, Ladanyi A, Penicka CV, George J, Matlin K, Montag A, Wroblewski K, Yamada SD, Mazar AP, Bowtell D, Lengyel E.

J Clin Invest. 2014 Oct;124(10):4614-28. doi: 10.1172/JCI74778. Epub 2014 Sep 9.


Statin therapy is associated with improved survival in patients with non-serous-papillary epithelial ovarian cancer: a retrospective cohort analysis.

Habis M, Wroblewski K, Bradaric M, Ismail N, Yamada SD, Litchfield L, Lengyel E, Romero IL.

PLoS One. 2014 Aug 13;9(8):e104521. doi: 10.1371/journal.pone.0104521. eCollection 2014.


Adipose tissue and adipocytes support tumorigenesis and metastasis.

Nieman KM, Romero IL, Van Houten B, Lengyel E.

Biochim Biophys Acta. 2013 Oct;1831(10):1533-41. doi: 10.1016/j.bbalip.2013.02.010. Epub 2013 Mar 14. Review.


Evaluation of silicon oil on bacterial growth.

Adams F, Romero IL, Silva CB, Manzano RP.

Arq Bras Oftalmol. 2012 Mar-Apr;75(2):89-91.


The use of 1% toluidine blue eye drops in the diagnosis of ocular surface squamous neoplasia.

Romero IL, Barros Jde N, Martins MC, Ballalai PL.

Cornea. 2013 Jan;32(1):36-9. doi: 10.1097/ICO.0b013e318243f61f.


Direct fluorescent antibody assay and polymerase chain reaction for the detection of Chlamydia trachomatis in patients with vernal keratoconjunctivitis.

Nishiwaki-Dantas MC, de Abreu MT, de Melo CM, Romero IL, Neto RB, Dantas PE.

Clinics (Sao Paulo). 2011;66(12):2013-8.


Relationship of type II diabetes and metformin use to ovarian cancer progression, survival, and chemosensitivity.

Romero IL, McCormick A, McEwen KA, Park S, Karrison T, Yamada SD, Pannain S, Lengyel E.

Obstet Gynecol. 2012 Jan;119(1):61-7. doi: 10.1097/AOG.0b013e3182393ab3.


Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.

Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E.

Nat Med. 2011 Oct 30;17(11):1498-503. doi: 10.1038/nm.2492.


The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.

Romero IL, Lee W, Mitra AK, Gordon IO, Zhao Y, Leonhardt P, Penicka CV, Mui KL, Krausz TN, Greene GL, Lengyel E.

Gynecol Oncol. 2012 Jan;124(1):134-41. doi: 10.1016/j.ygyno.2011.08.026. Epub 2011 Oct 11.


Foretinib (GSK1363089), an orally available multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces anoikis, and impairs ovarian cancer metastasis.

Zillhardt M, Park SM, Romero IL, Sawada K, Montag A, Krausz T, Yamada SD, Peter ME, Lengyel E.

Clin Cancer Res. 2011 Jun 15;17(12):4042-51. doi: 10.1158/1078-0432.CCR-10-3387. Epub 2011 May 6.


CD95 promotes tumour growth.

Chen L, Park SM, Tumanov AV, Hau A, Sawada K, Feig C, Turner JR, Fu YX, Romero IL, Lengyel E, Peter ME.

Nature. 2010 May 27;465(7297):492-6. doi: 10.1038/nature09075. Erratum in: Nature. 2011 Jul 14;475(7355):254. Nature. 2011 Mar 10;471(7337):254. Nature. 2012 Nov 29;491(7426):784.


[Epstein-Barr virus bilateral dacryoadenitis: case report].

Moscovici BK, Romero IL, Vital Filho J, Bison SH.

Arq Bras Oftalmol. 2009 Nov-Dec;72(6):826-8. Portuguese.


Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice.

Romero IL, Gordon IO, Jagadeeswaran S, Mui KL, Lee WS, Dinulescu DM, Krausz TN, Kim HH, Gilliam ML, Lengyel E.

Cancer Prev Res (Phila). 2009 Sep;2(9):792-9. doi: 10.1158/1940-6207.CAPR-08-0236. Epub 2009 Sep 8.


Antibacterial properties of cyanoacrylate tissue adhesive: Does the polymerization reaction play a role?

Romero IL, Malta JB, Silva CB, Mimica LM, Soong KH, Hida RY.

Indian J Ophthalmol. 2009 Sep-Oct;57(5):341-4. doi: 10.4103/0301-4738.55065.


Plasmacytoma of the orbit involving lacrimal gland with secondary transformation into multiple myeloma: case report.

Romero IL, Campos FA, Damasceno RW, Vital Filho J, Bison SH.

Arq Bras Oftalmol. 2009 Mar-Apr;72(2):236-8.


[Primary peripheral primitive neuroectodermal tumour of the orbit: case report].

Romero IL, Pereira LS, Campos FA, Vital Filho J, Bison SH.

Arq Bras Oftalmol. 2008 Nov-Dec;71(6):871-3. Portuguese.


Different application volumes of ethyl-cyanoacrylate tissue adhesive can change its antibacterial effects against ocular pathogens in vitro.

Romero IL, Paiato TP, Silva CB, Nigro JB, Malta S, Jenne Mimica LM, Soong HK, Hida RY.

Curr Eye Res. 2008 Oct;33(10):813-8. doi: 10.1080/02713680802437692.


Southwick's head-shaft angles: normal standards and abnormal values observed in obesity and in patients with epiphysiolysis.

Santili C, de Assis MC, Kusabara FI, Romero IL, Sartini CM, Longui CA.

J Pediatr Orthop B. 2004 Jul;13(4):244-7.


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