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Items: 1 to 50 of 71

1.

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.

Gantenbein N, Bernhart E, Anders I, Golob-Schwarzl N, Krassnig S, Wodlej C, Brcic L, Lindenmann J, Fink-Neuboeck N, Gollowitsch F, Stacher-Priehse E, Asslaber M, Gogg-Kamerer M, Rolff J, Hoffmann J, Silvestri A, Regenbrecht C, Reinhard C, Pehserl AM, Pichler M, Sokolova O, Naumann M, Mitterer V, Pertschy B, Bergler H, Popper H, Sattler W, Haybaeck J.

Eur J Cancer. 2018 Sep;101:165-180. doi: 10.1016/j.ejca.2018.07.001. Epub 2018 Aug 1.

2.

Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance.

Grasse S, Lienhard M, Frese S, Kerick M, Steinbach A, Grimm C, Hussong M, Rolff J, Becker M, Dreher F, Schirmer U, Boerno S, Ramisch A, Leschber G, Timmermann B, Grohé C, Lüders H, Vingron M, Fichtner I, Klein S, Odenthal M, Büttner R, Lehrach H, Sültmann H, Herwig R, Schweiger MR.

Genome Med. 2018 Jul 20;10(1):55. doi: 10.1186/s13073-018-0562-1.

3.

A constitutively expressed antifungal peptide protects Tenebrio molitor during a natural infection by the entomopathogenic fungus Beauveria bassiana.

Maistrou S, Paris V, Jensen AB, Rolff J, Meyling NV, Zanchi C.

Dev Comp Immunol. 2018 Sep;86:26-33. doi: 10.1016/j.dci.2018.04.015. Epub 2018 Apr 23.

PMID:
29698631
4.

GADD45A and CDKN1A are involved in apoptosis and cell cycle modulatory effects of viscumTT with further inactivation of the STAT3 pathway.

Kleinsimon S, Longmuss E, Rolff J, Jäger S, Eggert A, Delebinski C, Seifert G.

Sci Rep. 2018 Apr 10;8(1):5750. doi: 10.1038/s41598-018-24075-x.

5.

Cationic antimicrobial peptides do not change recombination frequency in Escherichia coli.

Rodríguez-Rojas A, Moreno-Morales J, Mason AJ, Rolff J.

Biol Lett. 2018 Mar;14(3). pii: 20180006. doi: 10.1098/rsbl.2018.0006.

PMID:
29563281
6.

Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics.

Yu G, Baeder DY, Regoes RR, Rolff J.

Proc Biol Sci. 2018 Mar 14;285(1874). pii: 20172687. doi: 10.1098/rspb.2017.2687.

PMID:
29540517
7.

Construction of Functional Coatings with Durable and Broad-Spectrum Antibacterial Potential Based on Mussel-Inspired Dendritic Polyglycerol and in Situ-Formed Copper Nanoparticles.

Li M, Gao L, Schlaich C, Zhang J, Donskyi IS, Yu G, Li W, Tu Z, Rolff J, Schwerdtle T, Haag R, Ma N.

ACS Appl Mater Interfaces. 2017 Oct 11;9(40):35411-35418. doi: 10.1021/acsami.7b10541. Epub 2017 Sep 27.

PMID:
28914053
8.

Synergistic Antitumour Properties of viscumTT in Alveolar Rhabdomyosarcoma.

Stammer RM, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, Delebinski CI.

J Immunol Res. 2017;2017:4874280. doi: 10.1155/2017/4874280. Epub 2017 Jul 16.

9.

Evolution of defence cocktails: Antimicrobial peptide combinations reduce mortality and persistent infection.

Zanchi C, Johnston PR, Rolff J.

Mol Ecol. 2017 Oct;26(19):5334-5343. doi: 10.1111/mec.14267. Epub 2017 Aug 30.

PMID:
28762573
10.

Animal models for personalized treatment options.

Fichtner I, Klinghammer K, Behrens D, Flechsig S, Rolff J, Becker M, Wulf-Goldenberg A, Stecklum M, Rivera M, Brzezicha B, Jandrig B, Hoffmann J.

Int J Clin Pharmacol Ther. 2017 Aug;55(8):698-700. doi: 10.5414/CPXCES15EA09. No abstract available.

PMID:
28696202
11.

Complete Genome Sequence of the Livestock-Associated Methicillin-Resistant Strain Staphylococcus aureus subsp. aureus 08S00974 (Sequence Type 398).

Makarova O, Johnston P, Walther B, Rolff J, Roesler U.

Genome Announc. 2017 May 11;5(19). pii: e00294-17. doi: 10.1128/genomeA.00294-17.

12.

Complete Genome Sequence of the Disinfectant Susceptibility Testing Reference Strain Staphylococcus aureus subsp. aureus ATCC 6538.

Makarova O, Johnston P, Walther B, Rolff J, Roesler U.

Genome Announc. 2017 May 11;5(19). pii: e00293-17. doi: 10.1128/genomeA.00293-17.

13.

Correction to 'Early life inflammation, immune response and ageing'.

Khan I, Agashe D, Rolff J.

Proc Biol Sci. 2017 Apr 12;284(1852). pii: 20170574. doi: 10.1098/rspb.2017.0574. No abstract available.

14.

Early-life inflammation, immune response and ageing.

Khan I, Agashe D, Rolff J.

Proc Biol Sci. 2017 Mar 15;284(1850). pii: 20170125. doi: 10.1098/rspb.2017.0125. Erratum in: Proc Biol Sci. 2017 Apr 12;284(1852):.

15.

The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.

Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL.

Sci Signal. 2017 Jan 3;10(460). pii: eaag1064. doi: 10.1126/scisignal.aag1064.

PMID:
28049763
16.

QSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.

Lienhard M, Grasse S, Rolff J, Frese S, Schirmer U, Becker M, Börno S, Timmermann B, Chavez L, Sültmann H, Leschber G, Fichtner I, Schweiger MR, Herwig R.

Nucleic Acids Res. 2017 Apr 7;45(6):e44. doi: 10.1093/nar/gkw1193.

17.

Multiple Active Compounds from Viscum album L. Synergistically Converge to Promote Apoptosis in Ewing Sarcoma.

Twardziok M, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, Delebinski CI.

PLoS One. 2016 Sep 2;11(9):e0159749. doi: 10.1371/journal.pone.0159749. eCollection 2016.

18.

Correction to: 'Antimicrobial defence and persistent infection in insects revisited'.

Makarova O, Rodríguez-Rojas A, Eravci M, Weise C, Dobson A, Johnston P, Rolff J.

Philos Trans R Soc Lond B Biol Sci. 2016 Jul 19;371(1699). pii: 20160263. doi: 10.1098/rstb.2016.0263. No abstract available.

19.

Genomic Signatures of Experimental Adaptation to Antimicrobial Peptides in Staphylococcus aureus.

Johnston PR, Dobson AJ, Rolff J.

G3 (Bethesda). 2016 Jun 1;6(6):1535-9. doi: 10.1534/g3.115.023622.

20.

Perspectives on the evolutionary ecology of arthropod antimicrobial peptides.

Rolff J, Schmid-Hempel P.

Philos Trans R Soc Lond B Biol Sci. 2016 May 26;371(1695). pii: 20150297. doi: 10.1098/rstb.2015.0297. Review.

21.

Antimicrobial defence and persistent infection in insects revisited.

Makarova O, Rodríguez-Rojas A, Eravci M, Weise C, Dobson A, Johnston P, Rolff J.

Philos Trans R Soc Lond B Biol Sci. 2016 May 26;371(1695). pii: 20150296. doi: 10.1098/rstb.2015.0296. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2016 Jul 19;371(1699). pii: 20160263. doi: 10.1098/rstb.2016.0263. Rodríguez-Rojas, Alex [corrected to Rodríguez-Rojas, Alexandro].

22.

Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models.

Baeder DY, Yu G, Hozé N, Rolff J, Regoes RR.

Philos Trans R Soc Lond B Biol Sci. 2016 May 26;371(1695). pii: 20150294. doi: 10.1098/rstb.2015.0294.

23.

Preclinical Study of a Combination of Erlotinib and Bevacizumab in Early Stages of Unselected Non-Small Cell Lung Cancer Patient-Derived Xenografts.

Rolff J, Becker M, Merk J, Hoffmann J, Fichtner I.

Target Oncol. 2016 Aug;11(4):507-14. doi: 10.1007/s11523-015-0415-4.

PMID:
26817645
24.

Intracellular survival of Staphylococcus aureus during persistent infection in the insect Tenebrio molitor.

McGonigle JE, Purves J, Rolff J.

Dev Comp Immunol. 2016 Jun;59:34-8. doi: 10.1016/j.dci.2016.01.002. Epub 2016 Jan 9.

PMID:
26778297
25.

Combination Effects of Antimicrobial Peptides.

Yu G, Baeder DY, Regoes RR, Rolff J.

Antimicrob Agents Chemother. 2016 Jan 4;60(3):1717-24. doi: 10.1128/AAC.02434-15.

26.

Investigation of cell culture volatilomes using solid phase micro extraction: Options and pitfalls exemplified with adenocarcinoma cell lines.

Schallschmidt K, Becker R, Jung C, Rolff J, Fichtner I, Nehls I.

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Dec 1;1006:158-166. doi: 10.1016/j.jchromb.2015.10.004. Epub 2015 Oct 20.

PMID:
26551208
27.

Host and Symbiont Jointly Control Gut Microbiota during Complete Metamorphosis.

Johnston PR, Rolff J.

PLoS Pathog. 2015 Nov 6;11(11):e1005246. doi: 10.1371/journal.ppat.1005246. eCollection 2015.

28.

Predictive In Vivo Models for Oncology.

Behrens D, Rolff J, Hoffmann J.

Handb Exp Pharmacol. 2016;232:203-21. Review.

PMID:
26489829
29.

Cationic Peptides Facilitate Iron-induced Mutagenesis in Bacteria.

Rodríguez-Rojas A, Makarova O, Müller U, Rolff J.

PLoS Genet. 2015 Oct 2;11(10):e1005546. doi: 10.1371/journal.pgen.1005546. eCollection 2015 Oct.

30.

Priming and memory of stress responses in organisms lacking a nervous system.

Hilker M, Schwachtje J, Baier M, Balazadeh S, Bäurle I, Geiselhardt S, Hincha DK, Kunze R, Mueller-Roeber B, Rillig MC, Rolff J, Romeis T, Schmülling T, Steppuhn A, van Dongen J, Whitcomb SJ, Wurst S, Zuther E, Kopka J.

Biol Rev Camb Philos Soc. 2016 Nov;91(4):1118-1133. doi: 10.1111/brv.12215. Epub 2015 Aug 20. Review.

PMID:
26289992
31.

A Natural Combination Extract of Viscum album L. Containing Both Triterpene Acids and Lectins Is Highly Effective against AML In Vivo.

Delebinski CI, Twardziok M, Kleinsimon S, Hoff F, Mulsow K, Rolff J, Jäger S, Eggert A, Seifert G.

PLoS One. 2015 Aug 5;10(8):e0133892. doi: 10.1371/journal.pone.0133892. eCollection 2015.

32.

Relaxed predation results in reduced phenotypic integration in a suite of dragonflies.

Mikolajewski DJ, Rüsen L, Mauersberger R, Johansson F, Rolff J.

J Evol Biol. 2015 Jul;28(7):1354-63. doi: 10.1111/jeb.12658. Epub 2015 Jun 8.

33.

Community priming--effects of sequential stressors on microbial assemblages.

Rillig MC, Rolff J, Tietjen B, Wehner J, Andrade-Linares DR.

FEMS Microbiol Ecol. 2015 May;91(5). pii: fiv040. doi: 10.1093/femsec/fiv040. Epub 2015 Apr 6.

PMID:
25873462
34.

In vitro cultured lung cancer cells are not suitable for animal-based breath biomarker detection.

Schallschmidt K, Becker R, Zwaka H, Menzel R, Johnen D, Fischer-Tenhagen C, Rolff J, Nehls I.

J Breath Res. 2015 Feb 10;9(2):027103. doi: 10.1088/1752-7155/9/2/027103.

PMID:
25667342
35.

Increased survival of experimentally evolved antimicrobial peptide-resistant Staphylococcus aureus in an animal host.

Dobson AJ, Purves J, Rolff J.

Evol Appl. 2014 Sep;7(8):905-12. doi: 10.1111/eva.12184. Epub 2014 Jul 2.

36.

Antimicrobials, stress and mutagenesis.

Rodríguez-Rojas A, Makarova O, Rolff J.

PLoS Pathog. 2014 Oct 9;10(10):e1004445. doi: 10.1371/journal.ppat.1004445. eCollection 2014 Oct.

37.

Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib.

Hülsmann HJ, Rolff J, Bender C, Jarahian M, Korf U, Herwig R, Fröhlich H, Thomas M, Merk J, Fichtner I, Sültmann H, Kuner R.

Lung Cancer. 2014 Nov;86(2):151-7. doi: 10.1016/j.lungcan.2014.09.001. Epub 2014 Sep 10.

PMID:
25240516
38.

Recognition, survival and persistence of Staphylococcus aureus in the model host Tenebrio molitor.

Dorling J, Moraes C, Rolff J.

Dev Comp Immunol. 2015 Feb;48(2):284-90. doi: 10.1016/j.dci.2014.08.010. Epub 2014 Aug 29.

PMID:
25179414
39.

Inducible defenses stay up late: temporal patterns of immune gene expression in Tenebrio molitor.

Johnston PR, Makarova O, Rolff J.

G3 (Bethesda). 2013 Dec 6;4(6):947-55. doi: 10.1534/g3.113.008516.

40.

Comparing selection on S. aureus between antimicrobial peptides and common antibiotics.

Dobson AJ, Purves J, Kamysz W, Rolff J.

PLoS One. 2013 Oct 18;8(10):e76521. doi: 10.1371/journal.pone.0076521. eCollection 2013.

41.

Immune- and wound-dependent differential gene expression in an ancient insect.

Johnston PR, Rolff J.

Dev Comp Immunol. 2013 Jul-Aug;40(3-4):320-4. doi: 10.1016/j.dci.2013.01.012. Epub 2013 Feb 8.

PMID:
23395998
42.

Identification of immunological expressed sequence tags in the mealworm beetle Tenebrio molitor.

Dobson AJ, Johnston PR, Vilcinskas A, Rolff J.

J Insect Physiol. 2012 Dec;58(12):1556-61. doi: 10.1016/j.jinsphys.2012.09.009. Epub 2012 Oct 4.

PMID:
23041376
43.

Quantitative genetics of immunity and life history under different photoperiods.

Hammerschmidt K, Deines P, Wilson AJ, Rolff J.

Heredity (Edinb). 2012 May;108(5):569-76. doi: 10.1038/hdy.2011.125. Epub 2011 Dec 21.

44.

Immune responses accelerate ageing: proof-of-principle in an insect model.

Pursall ER, Rolff J.

PLoS One. 2011;6(5):e19972. doi: 10.1371/journal.pone.0019972. Epub 2011 May 18.

45.

Immunology. Danger, microbes, and homeostasis.

Lazzaro BP, Rolff J.

Science. 2011 Apr 1;332(6025):43-4. doi: 10.1126/science.1200486. No abstract available.

PMID:
21454776
46.

Chemoresistance in non-small-cell lung cancer: can multidrug resistance markers predict the response of xenograft lung cancer models to chemotherapy?

Merk J, Rolff J, Dorn C, Leschber G, Fichtner I.

Eur J Cardiothorac Surg. 2011 Jul;40(1):e29-33. doi: 10.1016/j.ejcts.2011.02.010. Epub 2011 Mar 21.

PMID:
21420313
47.

Predator-driven trait diversification in a dragonfly genus: covariation in behavioral and morphological antipredator defense.

Mikolajewski DJ, De Block M, Rolff J, Johansson F, Beckerman AP, Stoks R.

Evolution. 2010 Nov;64(11):3327-25. doi: 10.1111/j.1558-5646.2010.01078.x.

PMID:
20624175
48.

Comparative profiling of the novel epothilone, sagopilone, in xenografts derived from primary non-small cell lung cancer.

Hammer S, Sommer A, Fichtner I, Becker M, Rolff J, Merk J, Klar U, Hoffmann J.

Clin Cancer Res. 2010 Mar 1;16(5):1452-65. doi: 10.1158/1078-0432.CCR-09-2455. Epub 2010 Feb 23.

49.

[Not Available].

Rolff J, Dorn C, Merk J, Fichtner I.

J Oncol. 2009;2009:814140. Epub 2009 Jun 14.

50.

Patient-derived xenografts of non-small-cell lung cancer: a pre-clinical model to evaluate adjuvant chemotherapy?

Merk J, Rolff J, Becker M, Leschber G, Fichtner I.

Eur J Cardiothorac Surg. 2009 Sep;36(3):454-9. doi: 10.1016/j.ejcts.2009.03.054. Epub 2009 Jun 6.

PMID:
19502076

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