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Items: 15


A protein-conjugate approach to develop a monoclonal antibody-based antigen detection test for the diagnosis of human brucellosis.

Patra KP, Saito M, Atluri VL, Rolán HG, Young B, Kerrinnes T, Smits H, Ricaldi JN, Gotuzzo E, Gilman RH, Tsolis RM, Vinetz JM.

PLoS Negl Trop Dis. 2014 Jun 5;8(6):e2926. doi: 10.1371/journal.pntd.0002926. eCollection 2014 Jun.


Identifying Yersinia YopH-targeted signal transduction pathways that impair neutrophil responses during in vivo murine infection.

Rolán HG, Durand EA, Mecsas J.

Cell Host Microbe. 2013 Sep 11;14(3):306-17. doi: 10.1016/j.chom.2013.08.013.


Innate immune recognition of flagellin limits systemic persistence of Brucella.

Terwagne M, Ferooz J, Rolán HG, Sun YH, Atluri V, Xavier MN, Franchi L, Núñez G, Legrand T, Flavell RA, De Bolle X, Letesson JJ, Tsolis RM.

Cell Microbiol. 2013 Jun;15(6):942-960. doi: 10.1111/cmi.12088. Epub 2013 Jan 7.


The small protein CydX is required for function of cytochrome bd oxidase in Brucella abortus.

Sun YH, de Jong MF, den Hartigh AB, Roux CM, Rolán HG, Tsolis RM.

Front Cell Infect Microbiol. 2012 Apr 13;2:47. doi: 10.3389/fcimb.2012.00047. eCollection 2012.


Innate immune encounters of the (Type) 4th kind: Brucella.

de Jong MF, Rolán HG, Tsolis RM.

Cell Microbiol. 2010 Sep 1;12(9):1195-202. doi: 10.1111/j.1462-5822.2010.01498.x. Epub 2010 Jul 28. Review.


ROS-inhibitory activity of YopE is required for full virulence of Yersinia in mice.

Songsungthong W, Higgins MC, Rolán HG, Murphy JL, Mecsas J.

Cell Microbiol. 2010 Jul;12(7):988-1001. doi: 10.1111/j.1462-5822.2010.01448.x. Epub 2010 Feb 9.


Natural antibody contributes to host defense against an attenuated Brucella abortus virB mutant.

Rolán HG, Xavier MN, Santos RL, Tsolis RM.

Infect Immun. 2009 Jul;77(7):3004-13. doi: 10.1128/IAI.01114-08. Epub 2009 Apr 13.


VirB3 to VirB6 and VirB8 to VirB11, but not VirB7, are essential for mediating persistence of Brucella in the reticuloendothelial system.

den Hartigh AB, Rolán HG, de Jong MF, Tsolis RM.

J Bacteriol. 2008 Jul;190(13):4427-36. doi: 10.1128/JB.00406-08. Epub 2008 May 9.


Inactivation of the type IV secretion system reduces the Th1 polarization of the immune response to Brucella abortus infection.

Rolán HG, Tsolis RM.

Infect Immun. 2008 Jul;76(7):3207-13. doi: 10.1128/IAI.00203-08. Epub 2008 May 5.


T cells help to amplify inflammatory responses induced by Salmonella enterica serotype Typhimurium in the intestinal mucosa.

Godinez I, Haneda T, Raffatellu M, George MD, Paixão TA, Rolán HG, Santos RL, Dandekar S, Tsolis RM, Bäumler AJ.

Infect Immun. 2008 May;76(5):2008-17. doi: 10.1128/IAI.01691-07. Epub 2008 Mar 17.


VirB12 is a serological marker of Brucella infection in experimental and natural hosts.

Rolán HG, den Hartigh AB, Kahl-McDonagh M, Ficht T, Adams LG, Tsolis RM.

Clin Vaccine Immunol. 2008 Feb;15(2):208-14. Epub 2007 Dec 12.


Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium.

Sun YH, Rolán HG, Tsolis RM.

J Biol Chem. 2007 Nov 23;282(47):33897-901. Epub 2007 Oct 1.


Brucella requires a functional Type IV secretion system to elicit innate immune responses in mice.

Roux CM, Rolán HG, Santos RL, Beremand PD, Thomas TL, Adams LG, Tsolis RM.

Cell Microbiol. 2007 Jul;9(7):1851-69. Epub 2007 Apr 17.


Mice lacking components of adaptive immunity show increased Brucella abortus virB mutant colonization.

Rolán HG, Tsolis RM.

Infect Immun. 2007 Jun;75(6):2965-73. Epub 2007 Apr 9.


Brucella abortus virB12 is expressed during infection but is not an essential component of the type IV secretion system.

Sun YH, Rolán HG, den Hartigh AB, Sondervan D, Tsolis RM.

Infect Immun. 2005 Sep;73(9):6048-54.

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