Sort by
Items per page

Send to

Choose Destination

Search results

Items: 20


A novel gene delivery method transduces porcine pancreatic duct epithelial cells.

Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB Jr, Davidson BL, Divekar A, Uc A.

Gene Ther. 2014 Feb;21(2):123-30. doi: 10.1038/gt.2013.62. Epub 2013 Nov 21.


Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Abou Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, Wallen TJ, Wohlford-Lenane C, McMenimen JD, Chen JH, Bogan KL, Adam RJ, Hornick EE, Nelson GA 4th, Hoffman EA, Chang EH, Zabner J, McCray PB Jr, Prather RS, Meyerholz DK, Welsh MJ.

J Clin Invest. 2013 Jun;123(6):2685-93. doi: 10.1172/JCI68867. Epub 2013 May 8.


Simplified and versatile method for isolation of high-quality RNA from pancreas.

Griffin M, Abu-El-Haija M, Abu-El-Haija M, Rokhlina T, Uc A.

Biotechniques. 2012 May;52(5):332-4. doi: 10.2144/0000113862.


The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs.

Ostedgaard LS, Meyerholz DK, Chen JH, Pezzulo AA, Karp PH, Rokhlina T, Ernst SE, Hanfland RA, Reznikov LR, Ludwig PS, Rogan MP, Davis GJ, Dohrn CL, Wohlford-Lenane C, Taft PJ, Rector MV, Hornick E, Nassar BS, Samuel M, Zhang Y, Richter SS, Uc A, Shilyansky J, Prather RS, McCray PB Jr, Zabner J, Welsh MJ, Stoltz DA.

Sci Transl Med. 2011 Mar 16;3(74):74ra24. doi: 10.1126/scitranslmed.3001868.


Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.

Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S, Rogan MP, Davis GJ, Hanfland RA, Wohlford-Lenane C, Dohrn CL, Bartlett JA, Nelson GA 4th, Chang EH, Taft PJ, Ludwig PS, Estin M, Hornick EE, Launspach JL, Samuel M, Rokhlina T, Karp PH, Ostedgaard LS, Uc A, Starner TD, Horswill AR, Brogden KA, Prather RS, Richter SS, Shilyansky J, McCray PB Jr, Zabner J, Welsh MJ.

Sci Transl Med. 2010 Apr 28;2(29):29ra31. doi: 10.1126/scitranslmed.3000928.


Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs.

Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, Samuel M, Wax D, Murphy CN, Rieke A, Whitworth K, Uc A, Starner TD, Brogden KA, Shilyansky J, McCray PB Jr, Zabner J, Prather RS, Welsh MJ.

Science. 2008 Sep 26;321(5897):1837-41. doi: 10.1126/science.1163600.


Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer.

Rogers CS, Hao Y, Rokhlina T, Samuel M, Stoltz DA, Li Y, Petroff E, Vermeer DW, Kabel AC, Yan Z, Spate L, Wax D, Murphy CN, Rieke A, Whitworth K, Linville ML, Korte SW, Engelhardt JF, Welsh MJ, Prather RS.

J Clin Invest. 2008 Apr;118(4):1571-7. doi: 10.1172/JCI34773.


Processing and function of CFTR-DeltaF508 are species-dependent.

Ostedgaard LS, Rogers CS, Dong Q, Randak CO, Vermeer DW, Rokhlina T, Karp PH, Welsh MJ.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15370-5. Epub 2007 Sep 14.


Vaccinia virus entry, exit, and interaction with differentiated human airway epithelia.

Vermeer PD, McHugh J, Rokhlina T, Vermeer DW, Zabner J, Welsh MJ.

J Virol. 2007 Sep;81(18):9891-9. Epub 2007 Jun 20. Erratum in: J Virol. 2007 Dec;81(23):13278.


A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia.

Ostedgaard LS, Rokhlina T, Karp PH, Lashmit P, Afione S, Schmidt M, Zabner J, Stinski MF, Chiorini JA, Welsh MJ.

Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2952-7. Epub 2005 Feb 9.


Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H+-activated currents in hippocampal neurons.

Askwith CC, Wemmie JA, Price MP, Rokhlina T, Welsh MJ.

J Biol Chem. 2004 Apr 30;279(18):18296-305. Epub 2004 Feb 11.


Segregation of receptor and ligand regulates activation of epithelial growth factor receptor.

Vermeer PD, Einwalter LA, Moninger TO, Rokhlina T, Kern JA, Zabner J, Welsh MJ.

Nature. 2003 Mar 20;422(6929):322-6.


Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia.

Ostedgaard LS, Randak C, Rokhlina T, Karp P, Vermeer D, Ashbourne Excoffon KJ, Welsh MJ.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1937-42. Epub 2003 Feb 10.


CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo.

Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3093-8. Epub 2002 Feb 19.


Cystic fibrosis transmembrane conductance regulator Cl- channels with R domain deletions and translocations show phosphorylation-dependent and -independent activity.

Baldursson O, Ostedgaard LS, Rokhlina T, Cotten JF, Welsh MJ.

J Biol Chem. 2001 Jan 19;276(3):1904-10. Epub 2000 Oct 18.


Homozygosity mapping of achromatopsia to chromosome 2 using DNA pooling.

Arbour NC, Zlotogora J, Knowlton RG, Merin S, Rosenmann A, Kanis AB, Rokhlina T, Stone EM, Sheffield VC.

Hum Mol Genet. 1997 May;6(5):689-94.


Fine mapping of the autosomal dominant juvenile open angle glaucoma (GLC1A) region and evaluation of candidate genes.

Sunden SL, Alward WL, Nichols BE, Rokhlina TR, Nystuen A, Stone EM, Sheffield VC.

Genome Res. 1996 Sep;6(9):862-9.


Use of a DNA pooling strategy to identify a human obesity syndrome locus on chromosome 15.

Carmi R, Rokhlina T, Kwitek-Black AE, Elbedour K, Nishimura D, Stone EM, Sheffield VC.

Hum Mol Genet. 1995 Jan;4(1):9-13.


Identification of a Bardet-Biedl syndrome locus on chromosome 3 and evaluation of an efficient approach to homozygosity mapping.

Sheffield VC, Carmi R, Kwitek-Black A, Rokhlina T, Nishimura D, Duyk GM, Elbedour K, Sunden SL, Stone EM.

Hum Mol Genet. 1994 Aug;3(8):1331-5.


[Sequence of 3372 RNA nucleotide links in the hepatitis A virus coding for capsid VP4-VP1 and nonstructural proteins].

Ovchinnikov IuA, Sverdlov ED, Tsarev SA, Arsenian SG, Rokhlina TO.

Dokl Akad Nauk SSSR. 1985;285(4):1014-8. Russian. No abstract available.


Supplemental Content

Loading ...
Support Center