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Items: 21

1.

RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE-dependent repression.

Liu P, Rojo de la Vega M, Sammani S, Mascarenhas JB, Kerins M, Dodson M, Sun X, Wang T, Ooi A, Garcia JGN, Zhang DD.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):E10352-E10361. doi: 10.1073/pnas.1812125115. Epub 2018 Oct 11.

2.

NRF2 and the Hallmarks of Cancer.

Rojo de la Vega M, Chapman E, Zhang DD.

Cancer Cell. 2018 Jul 9;34(1):21-43. doi: 10.1016/j.ccell.2018.03.022. Epub 2018 May 3. Review.

3.

NRF2 Induction for NASH Treatment: A New Hope Rises.

Rojo de la Vega M, Zhang DD.

Cell Mol Gastroenterol Hepatol. 2018 Jan 10;5(3):422-423. doi: 10.1016/j.jcmgh.2017.12.009. eCollection 2018 Mar. No abstract available.

4.

Topical Bixin Confers NRF2-Dependent Protection Against Photodamage and Hair Graying in Mouse Skin.

Rojo de la Vega M, Zhang DD, Wondrak GT.

Front Pharmacol. 2018 Mar 27;9:287. doi: 10.3389/fphar.2018.00287. eCollection 2018.

5.

Increased O-GlcNAcylation of SNAP29 Drives Arsenic-Induced Autophagic Dysfunction.

Dodson M, Liu P, Jiang T, Ambrose AJ, Luo G, Rojo de la Vega M, Cholanians AB, Wong PK, Chapman E, Zhang DD.

Mol Cell Biol. 2018 May 15;38(11). pii: e00595-17. doi: 10.1128/MCB.00595-17. Print 2018 Jun 1.

6.

Targeting NRF2 for Improved Skin Barrier Function and Photoprotection: Focus on the Achiote-Derived Apocarotenoid Bixin.

Rojo de la Vega M, Krajisnik A, Zhang DD, Wondrak GT.

Nutrients. 2017 Dec 18;9(12). pii: E1371. doi: 10.3390/nu9121371. Review.

7.

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).

Tian W, Rojo de la Vega M, Schmidlin CJ, Ooi A, Zhang DD.

J Biol Chem. 2018 Feb 9;293(6):2029-2040. doi: 10.1074/jbc.RA117.000428. Epub 2017 Dec 18.

8.

NRF2-targeted therapeutics: New targets and modes of NRF2 regulation.

Rojo de la Vega M, Dodson M, Chapman E, Zhang DD.

Curr Opin Toxicol. 2016 Dec;1:62-70. doi: 10.1016/j.cotox.2016.10.005. Epub 2016 Oct 12.

9.

The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer.

Tao S, Rojo de la Vega M, Chapman E, Ooi A, Zhang DD.

Mol Carcinog. 2018 Feb;57(2):182-192. doi: 10.1002/mc.22745. Epub 2017 Nov 6.

10.

p97 Negatively Regulates NRF2 by Extracting Ubiquitylated NRF2 from the KEAP1-CUL3 E3 Complex.

Tao S, Liu P, Luo G, Rojo de la Vega M, Chen H, Wu T, Tillotson J, Chapman E, Zhang DD.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00660-16. doi: 10.1128/MCB.00660-16. Print 2017 Apr 15.

11.

Response to comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis".

Wang H, Rojo de la Vega M, Zhang DD, Yu S, Zheng H.

Sci Transl Med. 2016 Jul 27;8(349):349lr1. doi: 10.1126/scitranslmed.aag1805.

PMID:
27464746
12.

Role of Nrf2 and Autophagy in Acute Lung Injury.

Rojo de la Vega M, Dodson M, Gross C, Mansour HM, Lantz RC, Chapman E, Wang T, Black SM, Garcia JG, Zhang DD.

Curr Pharmacol Rep. 2016 Apr;2(2):91-101. Epub 2016 Feb 6.

13.

NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis.

Wang H, Liu X, Long M, Huang Y, Zhang L, Zhang R, Zheng Y, Liao X, Wang Y, Liao Q, Li W, Tang Z, Tong Q, Wang X, Fang F, Rojo de la Vega M, Ouyang Q, Zhang DD, Yu S, Zheng H.

Sci Transl Med. 2016 Apr 13;8(334):334ra51. doi: 10.1126/scitranslmed.aad6095.

PMID:
27075625
14.

Bixin protects mice against ventilation-induced lung injury in an NRF2-dependent manner.

Tao S, Rojo de la Vega M, Quijada H, Wondrak GT, Wang T, Garcia JG, Zhang DD.

Sci Rep. 2016 Jan 5;6:18760. doi: 10.1038/srep18760.

15.

An Essential Role of NRF2 in Diabetic Wound Healing.

Long M, Rojo de la Vega M, Wen Q, Bharara M, Jiang T, Zhang R, Zhou S, Wong PK, Wondrak GT, Zheng H, Zhang DD.

Diabetes. 2016 Mar;65(3):780-93. doi: 10.2337/db15-0564. Epub 2015 Dec 30.

16.

Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention.

Harder B, Jiang T, Wu T, Tao S, Rojo de la Vega M, Tian W, Chapman E, Zhang DD.

Biochem Soc Trans. 2015 Aug;43(4):680-6. doi: 10.1042/BST20150020. Epub 2015 Aug 3. Review.

17.

Systemic administration of the apocarotenoid bixin protects skin against solar UV-induced damage through activation of NRF2.

Tao S, Park SL, Rojo de la Vega M, Zhang DD, Wondrak GT.

Free Radic Biol Med. 2015 Dec;89:690-700. doi: 10.1016/j.freeradbiomed.2015.08.028. Epub 2015 Nov 4.

18.

p62 links autophagy and Nrf2 signaling.

Jiang T, Harder B, Rojo de la Vega M, Wong PK, Chapman E, Zhang DD.

Free Radic Biol Med. 2015 Nov;88(Pt B):199-204. doi: 10.1016/j.freeradbiomed.2015.06.014. Epub 2015 Jun 24. Review.

19.

Nrf2-dependent suppression of azoxymethane/dextran sulfate sodium-induced colon carcinogenesis by the cinnamon-derived dietary factor cinnamaldehyde.

Long M, Tao S, Rojo de la Vega M, Jiang T, Wen Q, Park SL, Zhang DD, Wondrak GT.

Cancer Prev Res (Phila). 2015 May;8(5):444-54. doi: 10.1158/1940-6207.CAPR-14-0359. Epub 2015 Feb 23.

20.

The quinone methide aurin is a heat shock response inducer that causes proteotoxic stress and Noxa-dependent apoptosis in malignant melanoma cells.

Davis AL, Qiao S, Lesson JL, Rojo de la Vega M, Park SL, Seanez CM, Gokhale V, Cabello CM, Wondrak GT.

J Biol Chem. 2015 Jan 16;290(3):1623-38. doi: 10.1074/jbc.M114.592626. Epub 2014 Dec 4.

21.

The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.

Qiao S, Tao S, Rojo de la Vega M, Park SL, Vonderfecht AA, Jacobs SL, Zhang DD, Wondrak GT.

Autophagy. 2013 Dec;9(12):2087-102. doi: 10.4161/auto.26506. Epub 2013 Oct 8.

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