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Items: 27


CD40 in Endothelial Cells Restricts Neural Tissue Invasion by Toxoplasma gondii.

Portillo JC, Van Grol J, Saffo S, Lopez Corcino Y, Rodriguez M, Fox BA, Bzik DJ, Ward NL, Dubyak GR, Rojas RE, Toosi Z, Subauste CS.

Infect Immun. 2019 Jul 23;87(8). pii: e00868-18. doi: 10.1128/IAI.00868-18. Print 2019 Aug.


Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan.

Karim AF, Sande OJ, Tomechko SE, Ding X, Li M, Maxwell S, Ewing RM, Harding CV, Rojas RE, Chance MR, Boom WH.

Proteomics. 2017 Nov;17(22). doi: 10.1002/pmic.201700233.


The GalNAc-T Activation Pathway (GALA) is not a general mechanism for regulating mucin-type O-glycosylation.

Herbomel GG, Rojas RE, Tran DT, Ajinkya M, Beck L, Tabak LA.

PLoS One. 2017 Jul 18;12(7):e0179241. doi: 10.1371/journal.pone.0179241. eCollection 2017.


Toll like Receptor 2 engagement on CD4+ T cells promotes TH9 differentiation and function.

Karim AF, Reba SM, Li Q, Boom WH, Rojas RE.

Eur J Immunol. 2017 Sep;47(9):1513-1524. doi: 10.1002/eji.201646846. Epub 2017 Jul 18.


Novel high throughput pooled shRNA screening identifies NQO1 as a potential drug target for host directed therapy for tuberculosis.

Li Q, Karim AF, Ding X, Das B, Dobrowolski C, Gibson RM, Quiñones-Mateu ME, Karn J, Rojas RE.

Sci Rep. 2016 Jun 14;6:27566. doi: 10.1038/srep27566.


Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAIL.

Sande OJ, Karim AF, Li Q, Ding X, Harding CV, Rojas RE, Boom WH.

J Immunol. 2016 Jan 15;196(2):691-702. doi: 10.4049/jimmunol.1500710. Epub 2015 Dec 14.


TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.

Reba SM, Li Q, Onwuzulike S, Ding X, Karim AF, Hernandez Y, Fulton SA, Harding CV, Lancioni CL, Nagy N, Rodriguez ME, Wearsch PA, Rojas RE.

Eur J Immunol. 2014 May;44(5):1410-21. doi: 10.1002/eji.201344100. Epub 2014 Mar 14.


Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.

Rodriguez ME, Loyd CM, Ding X, Karim AF, McDonald DJ, Canaday DH, Rojas RE.

PLoS One. 2013 Nov 25;8(11):e80938. doi: 10.1371/journal.pone.0080938. eCollection 2013.


Human phagosome processing of Mycobacterium tuberculosis antigens is modulated by interferon-γ and interleukin-10.

Bobadilla K, Sada E, Jaime ME, González Y, Ramachandra L, Rojas RE, Pedraza-Sánchez S, Michalak C, González-Noriega A, Torres M.

Immunology. 2013 Jan;138(1):34-46. doi: 10.1111/imm.12010.


Mycobacterium tuberculosis ManLAM inhibits T-cell-receptor signaling by interference with ZAP-70, Lck and LAT phosphorylation.

Mahon RN, Sande OJ, Rojas RE, Levine AD, Harding CV, Boom WH.

Cell Immunol. 2012 Jan-Feb;275(1-2):98-105. doi: 10.1016/j.cellimm.2012.02.009. Epub 2012 Mar 14.


Rv2468c, a novel Mycobacterium tuberculosis protein that costimulates human CD4+ T cells through VLA-5.

Li Q, Ding X, Thomas JJ, Harding CV, Pecora ND, Ziady AG, Shank S, Boom WH, Lancioni CL, Rojas RE.

J Leukoc Biol. 2012 Feb;91(2):311-20. doi: 10.1189/jlb.0711364. Epub 2011 Dec 7.


Mycobacterium tuberculosis lipoproteins directly regulate human memory CD4(+) T cell activation via Toll-like receptors 1 and 2.

Lancioni CL, Li Q, Thomas JJ, Ding X, Thiel B, Drage MG, Pecora ND, Ziady AG, Shank S, Harding CV, Boom WH, Rojas RE.

Infect Immun. 2011 Feb;79(2):663-73. doi: 10.1128/IAI.00806-10. Epub 2010 Nov 15.


Mycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2.

Drage MG, Tsai HC, Pecora ND, Cheng TY, Arida AR, Shukla S, Rojas RE, Seshadri C, Moody DB, Boom WH, Sacchettini JC, Harding CV.

Nat Struct Mol Biol. 2010 Sep;17(9):1088-95. doi: 10.1038/nsmb.1869. Epub 2010 Aug 8.


Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling.

Mahon RN, Rojas RE, Fulton SA, Franko JL, Harding CV, Boom WH.

Infect Immun. 2009 Oct;77(10):4574-83. doi: 10.1128/IAI.00222-09. Epub 2009 Aug 3.


Activation requirements and responses to TLR ligands in human CD4+ T cells: comparison of two T cell isolation techniques.

Lancioni CL, Thomas JJ, Rojas RE.

J Immunol Methods. 2009 May 15;344(1):15-25. doi: 10.1016/j.jim.2009.02.005. Epub 2009 Mar 9.


CD4+ CD25(high) Foxp3+ regulatory T cells downregulate human Vdelta2+ T-lymphocyte function triggered by anti-CD3 or phosphoantigen.

Mahan CS, Thomas JJ, Boom WH, Rojas RE.

Immunology. 2009 Jul;127(3):398-407. doi: 10.1111/j.1365-2567.2008.02982.x. Epub 2008 Nov 14.


Phosphatidylinositol mannoside from Mycobacterium tuberculosis binds alpha5beta1 integrin (VLA-5) on CD4+ T cells and induces adhesion to fibronectin.

Rojas RE, Thomas JJ, Gehring AJ, Hill PJ, Belisle JT, Harding CV, Boom WH.

J Immunol. 2006 Sep 1;177(5):2959-68.


Role of phagosomes and major histocompatibility complex class II (MHC-II) compartment in MHC-II antigen processing of Mycobacterium tuberculosis in human macrophages.

Torres M, Ramachandra L, Rojas RE, Bobadilla K, Thomas J, Canaday DH, Harding CV, Boom WH.

Infect Immun. 2006 Mar;74(3):1621-30.


Vdelta2+ gammadelta T cell function in Mycobacterium tuberculosis- and HIV-1-positive patients in the United States and Uganda: application of a whole-blood assay.

Rojas RE, Chervenak KA, Thomas J, Morrow J, Nshuti L, Zalwango S, Mugerwa RD, Thiel BA, Whalen CC, Boom WH.

J Infect Dis. 2005 Nov 15;192(10):1806-14. Epub 2005 Oct 12.


Human immunity to M. tuberculosis: T cell subsets and antigen processing.

Boom WH, Canaday DH, Fulton SA, Gehring AJ, Rojas RE, Torres M.

Tuberculosis (Edinb). 2003;83(1-3):98-106. Review.


Cross-reactivity of anti-10kD heat shock protein antibodies in leprosy and tuberculosis patients.

Rojas RE, Demichelis SO, Giménez MF, Molinari ML, Segal-Eiras A.

Medicina (B Aires). 1997;57(5):581-6.


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