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Items: 40

1.

Crystal structure of the co-crystalline adduct 1,3,6,8-tetra-aza-tri-cyclo-[4.4.1.13,8]dodecane (TATD)-4-iodo-phenol (1/2): supra-molecular assembly mediated by halogen and hydrogen bonding.

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2017 Oct 20;73(Pt 11):1692-1695. doi: 10.1107/S2056989017014943. eCollection 2017 Nov 1.

2.

C-I⋯N short contacts as tools for the construction of the crystal packing in the crystal structure of 3,3'-(ethane-1,2-di-yl)bis-(6-iodo-3,4-di-hydro-2H-1,3-benzoxazine).

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2017 Apr 7;73(Pt 5):664-666. doi: 10.1107/S2056989017005047. eCollection 2017 May 1.

3.

Preliminary results on the control of Aedes spp. in a remote Guatemalan community vulnerable to dengue, chikungunya and Zika virus: community participation and use of low-cost ecological ovillantas for mosquito control.

Ulibarri G, Betanzos A, Betanzos M, Rojas JJ.

Version 3. F1000Res. 2016 Apr 7 [revised 2017 Jan 1];5:598. doi: 10.12688/f1000research.8461.3. eCollection 2016.

4.

Mechanochemical synthesis and crystal structure of a 1:2 co-crystal of 1,3,6,8-tetra-aza-tri-cyclo[4.3.1.13,8]undecane (TATU) and 4-chloro-3,5-dimethyl-phenol.

Rivera A, Rojas JJ, Sadat-Bernal J, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2016 Oct 25;72(Pt 11):1651-1653. eCollection 2016 Nov 1.

5.

Crystal structure of the 1:2 co-crystal of 1,3,6,8-tetra-aza-tri-cyclo-[4.3.1.13,8]undecane (TATU) and 4-chloro-phenol (1/2).

Rivera A, Rojas JJ, Osorio HJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2016 Oct 25;72(Pt 11):1648-1650. eCollection 2016 Nov 1.

6.

Crystal structure of 1,2-bis-(6-bromo-3,4-dihydro-2H-benz[e][1,3]oxazin-3-yl)ethane: a bromine-containing bis-benzoxazine.

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2016 Oct 25;72(Pt 11):1645-1647. eCollection 2016 Nov 1.

7.

Crystal structure and C-H⋯F hydrogen bonding in the fluorinated bis-benzoxazine: 3,3'-(ethane-1,2-di-yl)bis-(6-fluoro-3,4-di-hydro-2H-1,3-benzoxazine).

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2016 Sep 30;72(Pt 10):1509-1511. eCollection 2016 Oct 1.

8.

Oncolytic Virus-Mediated Targeting of PGE2 in the Tumor Alters the Immune Status and Sensitizes Established and Resistant Tumors to Immunotherapy.

Hou W, Sampath P, Rojas JJ, Thorne SH.

Cancer Cell. 2016 Jul 11;30(1):108-119. doi: 10.1016/j.ccell.2016.05.012. Epub 2016 Jun 30.

9.

Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies.

Rojas JJ, Sampath P, Bonilla B, Ashley A, Hou W, Byrd D, Thorne SH.

Cell Rep. 2016 Apr 12;15(2):264-73. doi: 10.1016/j.celrep.2016.03.017. Epub 2016 Mar 31.

10.

Early environmental enrichment affects neurobehavioral development and prevents brain damage in rats submitted to neonatal hypoxia-ischemia.

Schuch CP, Diaz R, Deckmann I, Rojas JJ, Deniz BF, Pereira LO.

Neurosci Lett. 2016 Mar 23;617:101-7. doi: 10.1016/j.neulet.2016.02.015. Epub 2016 Feb 9.

PMID:
26872850
11.

Folic Acid Can Contribute to Memory Deficit and Na+, K+- ATPase Failure in the Hippocampus of Adolescent Rats Submitted to Hypoxia- Ischemia.

Carletti JV, Deniz BF, Rojas JJ, Miguel PM, Kolling J, Scherer EB, de Souza Wyse AT, Netto CA, Pereira LO.

CNS Neurol Disord Drug Targets. 2016;15(1):64-72.

PMID:
26553162
12.

Crystal structure of 1-[(2,3-dihydro-1H-naphtho-[1,2-e][1,3]oxazin-2-yl)meth-yl]naphthalen-2-ol: a possible candidate for new polynaphthoxazine materials.

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2015 Aug 26;71(Pt 9):1089-92. doi: 10.1107/S2056989015015583. eCollection 2015 Sep 1.

13.

Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging.

Zhang M, Chakraborty SK, Sampath P, Rojas JJ, Hou W, Saurabh S, Thorne SH, Bruchez MP, Waggoner AS.

J Clin Invest. 2015 Oct 1;125(10):3915-27. doi: 10.1172/JCI81086. Epub 2015 Sep 8.

14.

Crystal structure of the co-crystalline adduct 1,3,6,8-tetra-aza-tri-cyclo-[4.4.1.1(3,8)]dodecane (TATD)-4-chloro-3,5-di-methyl-phenol (1/1).

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2015 Jun 3;71(Pt 7):737-40. doi: 10.1107/S2056989015010257. eCollection 2015 Jul 1.

15.

Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy.

Rojas JJ, Sampath P, Hou W, Thorne SH.

Clin Cancer Res. 2015 Dec 15;21(24):5543-51. doi: 10.1158/1078-0432.CCR-14-2009. Epub 2015 Jul 17.

16.

Neonatal hypoxia-ischemia induces attention-deficit hyperactivity disorder-like behavior in rats.

Miguel PM, Schuch CP, Rojas JJ, Carletti JV, Deckmann I, Martinato LH, Pires AV, Bizarro L, Pereira LO.

Behav Neurosci. 2015 Jun;129(3):309-20. doi: 10.1037/bne0000063.

PMID:
26030430
17.

Crystal structure of the co-crystalline adduct 1,3,6,8-tetra-aza-tri-cyclo-[4.4.1.1(3,8)]dodecane (TATD)-4-bromo-phenol (1/2).

Rivera A, Uribe JM, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2015 Apr 9;71(Pt 5):463-5. doi: 10.1107/S2056989015006684. eCollection 2015 May 1.

18.

Crystal structure of 1,1'-[imidazolidine-1,3-diylbis(methyl-ene)]bis-(naphthalen-2-ol).

Rivera A, Rojas JJ, Ríos-Motta J, Bolte M.

Acta Crystallogr E Crystallogr Commun. 2015 Feb 7;71(Pt 3):258-60. doi: 10.1107/S2056989015002078. eCollection 2015 Mar 1.

19.

Environmental stimulation improves performance in the ox-maze task and recovers Na+,K+-ATPase activity in the hippocampus of hypoxic-ischemic rats.

Rojas JJ, Deniz BF, Schuch CP, Carletti JV, Deckmann I, Diaz R, Matté C, dos Santos TM, Wyse AT, Netto CA, Pereira LO.

Neuroscience. 2015 Apr 16;291:118-27. doi: 10.1016/j.neuroscience.2015.01.017. Epub 2015 Jan 21.

PMID:
25617656
20.

Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression.

Rodríguez-García A, Giménez-Alejandre M, Rojas JJ, Moreno R, Bazan-Peregrino M, Cascalló M, Alemany R.

Clin Cancer Res. 2015 Mar 15;21(6):1406-18. doi: 10.1158/1078-0432.CCR-14-2213. Epub 2014 Nov 12.

21.

International physical activity questionnaire overestimation is ameliorated by individual analysis of the scores.

Bermúdez VJ, Rojas JJ, Córdova EB, Añez R, Toledo A, Aguirre MA, Cano C, Arraiz N, Velasco M, López-Miranda J.

Am J Ther. 2013 Jul-Aug;20(4):448-58. doi: 10.1097/MJT.0b013e318235f1f2.

PMID:
23838635
22.

Effects of daily environmental enrichment on behavior and dendritic spine density in hippocampus following neonatal hypoxia-ischemia in the rat.

Rojas JJ, Deniz BF, Miguel PM, Diaz R, Hermel Edo E, Achaval M, Netto CA, Pereira LO.

Exp Neurol. 2013 Mar;241:25-33. doi: 10.1016/j.expneurol.2012.11.026. Epub 2012 Dec 6.

23.

Folic acid prevents behavioral impairment and Na(+), K(+) -ATPase inhibition caused by neonatal hypoxia-ischemia.

Carletti JV, Deniz BF, Miguel PM, Rojas JJ, Kolling J, Scherer EB, de Souza Wyse AT, Netto CA, Pereira LO.

Neurochem Res. 2012 Aug;37(8):1624-30. doi: 10.1007/s11064-012-0757-6. Epub 2012 Apr 22.

PMID:
22528830
24.

Theranostic potential of oncolytic vaccinia virus.

Rojas JJ, Thorne SH.

Theranostics. 2012;2(4):363-73. doi: 10.7150/thno.3724. Epub 2012 Apr 5.

25.

GALV expression enhances the therapeutic efficacy of an oncolytic adenovirus by inducing cell fusion and enhancing virus distribution.

Guedan S, Grases D, Rojas JJ, Gros A, Vilardell F, Vile R, Mercade E, Cascallo M, Alemany R.

Gene Ther. 2012 Nov;19(11):1048-57. doi: 10.1038/gt.2011.184. Epub 2011 Nov 24.

PMID:
22113313
26.

Improved systemic antitumor therapy with oncolytic adenoviruses by replacing the fiber shaft HSG-binding domain with RGD.

Rojas JJ, Gimenez-Alejandre M, Gil-Hoyos R, Cascallo M, Alemany R.

Gene Ther. 2012 Apr;19(4):453-7. doi: 10.1038/gt.2011.106. Epub 2011 Jul 21.

PMID:
21776023
27.

4,4'-Dibromo-2,2'-{ethane-1,2-diylbis[(methyl-imino)-methyl-ene]}diphenol.

Rivera A, Rojas JJ, Ríos-Motta J, Dušek M, Fejfarová K.

Acta Crystallogr Sect E Struct Rep Online. 2011 Jun 1;67(Pt 6):o1391. doi: 10.1107/S1600536811017193. Epub 2011 May 14.

28.

Pharmacological developments obtained from marine natural products and current pipeline perspective.

Galeano E, Rojas JJ, Martínez A.

Nat Prod Commun. 2011 Feb;6(2):287-300. Review.

PMID:
21425696
29.

Minimal RB-responsive E1A promoter modification to attain potency, selectivity, and transgene-arming capacity in oncolytic adenoviruses.

Rojas JJ, Guedan S, Searle PF, Martinez-Quintanilla J, Gil-Hoyos R, Alcayaga-Miranda F, Cascallo M, Alemany R.

Mol Ther. 2010 Nov;18(11):1960-71. doi: 10.1038/mt.2010.173. Epub 2010 Aug 31.

30.

Osteosarcoma cells as carriers to allow antitumor activity of canine oncolytic adenovirus in the presence of neutralizing antibodies.

Alcayaga-Miranda F, Cascallo M, Rojas JJ, Pastor J, Alemany R.

Cancer Gene Ther. 2010 Nov;17(11):792-802. doi: 10.1038/cgt.2010.36. Epub 2010 Jul 30.

PMID:
20671769
31.

Synthesis of a new series of N,N'-dimethyltetrahydrosalen (H2[H2Me]salen) ligands by the reductive ring-opening of 3,3'-ethylene-bis(3,4-dihydro-6-substituted-2H-1,3-benzoxazines).

Rivera A, Rojas JJ, Salazar-Barrios J, Maldonado M, Ríos-Motta J.

Molecules. 2010 Jun 7;15(6):4102-10. doi: 10.3390/molecules15064102.

32.

Hyaluronidase expression by an oncolytic adenovirus enhances its intratumoral spread and suppresses tumor growth.

Guedan S, Rojas JJ, Gros A, Mercade E, Cascallo M, Alemany R.

Mol Ther. 2010 Jul;18(7):1275-83. doi: 10.1038/mt.2010.79. Epub 2010 May 4.

33.

Verapamil enhances the antitumoral efficacy of oncolytic adenoviruses.

Gros A, Puig C, Guedan S, Rojas JJ, Alemany R, Cascallo M.

Mol Ther. 2010 May;18(5):903-11. doi: 10.1038/mt.2010.22. Epub 2010 Feb 23.

34.

3,3'-Ethyl-enebis(3,4-dihydro-6-chloro-2H-1,3-benzoxazine).

Rivera A, Rojas JJ, Ríos-Motta J, Dušek M, Fejfarová K.

Acta Crystallogr Sect E Struct Rep Online. 2010 Apr 21;66(Pt 5):o1134. doi: 10.1107/S1600536810014248.

35.

A modified E2F-1 promoter improves the efficacy to toxicity ratio of oncolytic adenoviruses.

Rojas JJ, Cascallo M, Guedan S, Gros A, Martinez-Quintanilla J, Hemminki A, Alemany R.

Gene Ther. 2009 Dec;16(12):1441-51. doi: 10.1038/gt.2009.103.

PMID:
19710704
36.

Systemic toxicity-efficacy profile of ICOVIR-5, a potent and selective oncolytic adenovirus based on the pRB pathway.

Cascallo M, Alonso MM, Rojas JJ, Perez-Gimenez A, Fueyo J, Alemany R.

Mol Ther. 2007 Sep;15(9):1607-15. Epub 2007 Jun 19.

38.

Piperacillin/tazobactam in the treatment of hospitalized patients with urinary tract infections: an open non-comparative and multicentered trial.

Sifuentes-Osornio J, Jakob E, Clara L, Durlach R, Dain A, Ruìz-Palacios GM, Barkan L, Lamberghini R, Jáuregui A, Villalobos Y, Sáenz-Aguirre C, de la Cabada FJ, Rodríguez-Toledo A, Zavala-Trujillo I, Gamboa MA, Fuentes del Toro S, Froiler C, Maglio F, Quiroga JV, Rojas JJ, Conde-Carmona I.

J Chemother. 1996 Apr;8(2):122-9.

PMID:
8708743
39.

Piperacillin/tazobactam in the treatment of lower respiratory tract infections: an open non-comparative and multicentered trial. Latin American Clinical Research Group.

Sifuentes-Osornio J, Ruíz-Palacios GM, Jakob E, Rojas JJ, Jáuregui A, Villalobos Y.

J Chemother. 1994 Jun;6(3):197-203.

PMID:
7983503
40.

[Evaluation of the use of sodium bicarbonate in a group of children with diarrhea, 10 per cent dehydration and metabolic acidosis].

Portocarrero AC, Flores MD, Pineda RG, Chaverri AR, Rojas JJ, Molina YE, Cortés RL.

Bol Med Hosp Infant Mex. 1976 May-Jun;33(3):495-506. Spanish.

PMID:
1275956

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