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Items: 1 to 50 of 263

1.

Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine.

Kvirkvelia N, Chikadze N, Makinde J, McBride JD, Porakishvili N, Hills FA, Martensen PM, Justesen J, Delves PJ, Lund T, Roitt IM.

Clin Exp Immunol. 2018 Jul;193(1):73-83. doi: 10.1111/cei.13131. Epub 2018 May 7.

PMID:
29601077
2.

Lipoxin A4 selectively programs the profile of M2 tumor-associated macrophages which favour control of tumor progression.

Simões RL, De-Brito NM, Cunha-Costa H, Morandi V, Fierro IM, Roitt IM, Barja-Fidalgo C.

Int J Cancer. 2017 Jan 15;140(2):346-357. doi: 10.1002/ijc.30424. Epub 2016 Oct 31.

3.

Glucose-coated gold nanoparticles transfer across human brain endothelium and enter astrocytes in vitro.

Gromnicova R, Davies HA, Sreekanthreddy P, Romero IA, Lund T, Roitt IM, Phillips JB, Male DK.

PLoS One. 2013 Dec 5;8(12):e81043. doi: 10.1371/journal.pone.0081043. eCollection 2013.

4.

The influence of ligand organization on the rate of uptake of gold nanoparticles by colorectal cancer cells.

Lund T, Callaghan MF, Williams P, Turmaine M, Bachmann C, Rademacher T, Roitt IM, Bayford R.

Biomaterials. 2011 Dec;32(36):9776-84. doi: 10.1016/j.biomaterials.2011.09.018. Epub 2011 Sep 22.

PMID:
21944722
5.

A human domain antibody and Lewis b glycoconjugate that inhibit binding of Helicobacter pylori to Lewis b receptor and adhesion to human gastric epithelium.

Younson J, O'Mahony R, Liu H, Basset C, Grant S, Campion C, Jennings L, Vaira D, Kelly CG, Roitt IM, Holton J.

J Infect Dis. 2009 Nov 15;200(10):1574-82. doi: 10.1086/644596. Erratum in: J Infect Dis. 2010 Feb 1;201(3):481. Basset, Christelle [added].

PMID:
19832116
6.

Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA).

McBride JD, Gabriel FG, Fordham J, Kolind T, Barcenas-Morales G, Isenberg DA, Swana M, Delves PJ, Lund T, Cree IA, Roitt IM.

Clin Chem. 2008 May;54(5):883-90. doi: 10.1373/clinchem.2007.098418. Epub 2008 Mar 20.

8.

Human domain antibodies against virulence traits of Candida albicans inhibit fungus adherence to vaginal epithelium and protect against experimental vaginal candidiasis.

De Bernardis F, Liu H, O'Mahony R, La Valle R, Bartollino S, Sandini S, Grant S, Brewis N, Tomlinson I, Basset RC, Holton J, Roitt IM, Cassone A.

J Infect Dis. 2007 Jan 1;195(1):149-57. Epub 2006 Nov 20.

PMID:
17152019
9.

Designing a new generation of anti-hCG vaccines for cancer therapy.

Delves PJ, Iles RK, Roitt IM, Lund T.

Mol Cell Endocrinol. 2007 Jan 2;260-262:276-81. Epub 2006 Oct 17.

PMID:
17049720
10.

Vaccines for the control of reproduction--status in mammals, and aspects of comparative interest.

Delves PJ, Roitt IM.

Dev Biol (Basel). 2005;121:265-73. Review.

PMID:
15962489
11.

The human chorionic gonadotropin-beta arginine68 to glutamic acid substitution fixes the conformation of the C-terminal peptide.

Charrel-Dennis M, Terrazzini N, McBride JD, Kaye P, Martensen PM, Justesen J, Berger P, Lapthorn A, Kelly C, Roitt IM, Delves PJ, Lund T.

Mol Endocrinol. 2005 Jul;19(7):1803-11. Epub 2005 Feb 17.

PMID:
15718290
12.

Changes in the reproductive system of male mice immunized with a GnRH-analogue conjugated to mycobacterial hsp70.

Hannesdóttir SG, Han X, Lund T, Singh M, Van Der Zee R, Roitt IM, Delves PJ.

Reproduction. 2004 Sep;128(3):365-71.

PMID:
15333787
13.

The major hormone-specific discontinuous epitopes on human chorionic gonadotrophin.

Charrel-Dennis M, Jackson AM, Lund T, Lapthorn AJ, Berger P, Roitt IM, Delves PJ.

J Mol Endocrinol. 2004 Apr;32(2):571-81.

PMID:
15072560
14.

Elimination of luteinizing hormone cross-reactive epitopes from human chorionic gonadotropin.

Porakishvili N, Chiesa MD, Chikadze N, Martensen P, Justesen J, Lund T, Delves PJ, Roitt IM.

Vaccine. 2002 May 15;20(16):2053-9.

PMID:
11972973
15.

Future prospects for vaccines to control fertility.

Delves PJ, Lund T, Roitt IM.

Trends Immunol. 2002 Apr;23(4):220-1.

PMID:
11923118
16.

Antifertility vaccines.

Delves PJ, Lund T, Roitt IM.

Trends Immunol. 2002 Apr;23(4):213-9. Review.

PMID:
11923117
17.

Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells.

Kvirkvelia N, Vojnovic I, Warner TD, Athie-Morales V, Free P, Rayment N, Chain BM, Rademacher TW, Lund T, Roitt IM, Delves PJ.

Clin Exp Immunol. 2002 Feb;127(2):263-9.

18.

Refocusing of B-cell responses following a single amino acid substitution in an antigen.

Chiesa MD, Martensen PM, Simmons C, Porakishvili N, Justesen J, Dougan G, Roitt IM, Delves PJ, Lund T.

Immunology. 2001 Jun;103(2):172-8.

19.

The immune system. Second of two parts.

Delves PJ, Roitt IM.

N Engl J Med. 2000 Jul 13;343(2):108-17. Review. No abstract available.

PMID:
10891520
20.

The immune system. First of two parts.

Delves PJ, Roitt IM.

N Engl J Med. 2000 Jul 6;343(1):37-49. Review. No abstract available.

PMID:
10882768
21.

Increased N-linked glycosylation leading to oversialylation of monomeric immunoglobulin A1 from patients with Sjögren's syndrome.

Basset C, Durand V, Jamin C, Clément J, Pennec Y, Youinou P, Dueymes M, Roitt IM.

Scand J Immunol. 2000 Mar;51(3):300-6.

22.

A low budget luminometer for sensitive chemiluminescent immunoassays.

Porakishvili N, Fordham JL, Charrel M, Delves PJ, Lund T, Roitt IM.

J Immunol Methods. 2000 Feb 3;234(1-2):35-42.

PMID:
10669767
23.

Dual specificity antibodies using a double-stranded oligonucleotide bridge.

Chaudri ZN, Bartlet-Jones M, Panayotou G, Klonisch T, Roitt IM, Lund T, Delves PJ.

FEBS Lett. 1999 Apr 30;450(1-2):23-6.

24.

The effect of low-profile serine substitutions in the V3 loop of HIV-1 gp120 IIIB/LAI on the immunogenicity of the envelope protein.

Peet NM, McKeating JA, de Souza JB, Roitt IM, Delves PJ, Lund T.

Virology. 1998 Nov 10;251(1):59-70.

25.

Epitopes of human chorionic gonadotropin and their relationship to immunogenicity and cross-reactivity of beta-chain mutants.

Porakishvili N, Jackson AM, de Souza JB, Dalla Chiesa M, Roitt IM, Delves PJ, Lund T.

Am J Reprod Immunol. 1998 Sep;40(3):210-4.

PMID:
9764366
26.

Can epitope-focused vaccines select advantageous immune responses?

Delves PJ, Lund T, Roitt IM.

Mol Med Today. 1997 Feb;3(2):55-60. Review.

PMID:
9060002
27.

Enhancement in antigen binding by a combination of synergy and antibody capture.

Klonisch T, Panayotou G, Edwards P, Jackson AM, Berger P, Delves PJ, Lund T, Roitt IM.

Immunology. 1996 Oct;89(2):165-71.

28.

Identification and selective destruction of shared epitopes in human chorionic gonadotropin beta subunit.

Jackson AM, Klonisch T, Lapthorn AJ, Berger P, Isaacs NW, Delves PJ, Lund T, Roitt IM.

J Reprod Immunol. 1996 Aug;31(1-2):21-36.

PMID:
8887120
29.

Relative location of epitopes involved in synergistic antibody binding using human chorionic gonadotropin as a model.

Klonisch T, Delves PJ, Berger P, Panayotou G, Lapthorn AJ, Isaacs NW, Wick G, Lund T, Roitt IM.

Eur J Immunol. 1996 Aug;26(8):1897-905.

PMID:
8765037
30.

Unique role of thyroxine in T cell recognition of a pathogenic peptide in experimental autoimmune thyroiditis.

Dawe KI, Hutchings PR, Geysen M, Champion BR, Cooke A, Roitt IM.

Eur J Immunol. 1996 Apr;26(4):768-72.

PMID:
8625966
31.

Production of erythrocyte autoantibodies in NZB mice is inhibited by CD4 antibodies.

Oliveira GG, Hutchings PR, Roitt IM, Lydyard PM.

Clin Exp Immunol. 1994 May;96(2):297-302.

32.

IgG glycosylation in autoimmune-prone strains of mice.

Bodman KB, Hutchings PR, Jeddi PA, Delves PJ, Rook GA, Sumar N, Roitt IM, Lydyard PM.

Clin Exp Immunol. 1994 Jan;95(1):103-7.

33.

Active suppression induced by anti-CD4.

Hutchings PR, Cooke A, Dawe K, Waldmann H, Roitt IM.

Eur J Immunol. 1993 Apr;23(4):965-8.

PMID:
8096186
34.
35.

The regulation of autoimmunity through CD4+ T cells.

Hutchings P, Parish N, O'Reilly L, Dawe K, Roitt IM, Cooke A.

Autoimmunity. 1993;15 Suppl:21-3. Review.

PMID:
8105991
36.

The role of autoantigens in the driving of autoimmune diseases.

Roitt IM.

Immunol Ser. 1993;59:119-29. Review. No abstract available.

PMID:
7681695
37.

Lymphocytes from patients with rheumatoid arthritis produce agalactosylated IgG in vitro.

Bodman KB, Sumar N, Mackenzie LE, Isenberg DA, Hay FC, Roitt IM, Lydyard PM.

Clin Exp Immunol. 1992 Jun;88(3):420-3.

38.

The forces driving autoimmune disease.

Roitt IM, Hutchings PR, Dawe KI, Sumar N, Bodman KB, Cooke A.

J Autoimmun. 1992 Apr;5 Suppl A:11-26. Review.

PMID:
1380240
39.

A thyroxine-containing peptide can induce murine experimental autoimmune thyroiditis.

Hutchings PR, Cooke A, Dawe K, Champion BR, Geysen M, Valerio R, Roitt IM.

J Exp Med. 1992 Mar 1;175(3):869-72.

40.

Changes in normal glycosylation mechanisms in autoimmune rheumatic disease.

Axford JS, Sumar N, Alavi A, Isenberg DA, Young A, Bodman KB, Roitt IM.

J Clin Invest. 1992 Mar;89(3):1021-31.

41.

Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy.

Rook GA, Steele J, Brealey R, Whyte A, Isenberg D, Sumar N, Nelson JL, Bodman KB, Young A, Roitt IM, et al.

J Autoimmun. 1991 Oct;4(5):779-94.

PMID:
1797027
42.

Reduction in IgG galactose in juvenile and adult onset rheumatoid arthritis measured by a lectin binding method and its relation to rheumatoid factor.

Sumar N, Isenberg DA, Bodman KB, Soltys A, Young A, Leak AM, Round J, Hay FC, Roitt IM.

Ann Rheum Dis. 1991 Sep;50(9):607-10.

43.

In vitro regulation of thyroglobulin (Tg) autoantibody production by Tg-specific T-cell lines and hybridomas.

Champion BR, Hutchings P, Rayner DC, Page K, Tite J, Cooke A, Roitt IM.

Immunology. 1991 Aug;73(4):415-20.

44.

Identification of a thyroxine-containing self-epitope of thyroglobulin which triggers thyroid autoreactive T cells.

Champion BR, Page KR, Parish N, Rayner DC, Dawe K, Biswas-Hughes G, Cooke A, Geysen M, Roitt IM.

J Exp Med. 1991 Aug 1;174(2):363-70.

45.

IgG and rheumatoid factor at a glance.

Roitt IM, Sumar N.

Clin Exp Rheumatol. 1990 Jul-Aug;8 Suppl 5:89-91.

PMID:
2245533
46.

Comment on the article by Tomana et al.

Axford JS, Bodman K, Hay FC, Isenberg DA, Lydyard PM, Mackenzie L, Roitt IM, Sumar N, Rook G, Dwek RA, et al.

Arthritis Rheum. 1989 Feb;32(2):235-6. No abstract available.

PMID:
2920059
47.

Cellular infiltration in induced rat thyroiditis: phenotypic analysis and relationship to genetic restriction.

De Assis-Paiva HJ, Rayner DC, Roitt IM, Cooke A.

Clin Exp Immunol. 1989 Jan;75(1):106-12.

48.

Basic concepts and new aspects of vaccine development.

Roitt IM.

Parasitology. 1989;98 Suppl:S7-12. Review. No abstract available.

PMID:
2471132
49.

Epitope specificity of spontaneous and induced thyroglobulin autoantibodies in the rat.

De Assis-Paiva HJ, Champion B, Rayner DC, Colle E, Bone A, Roitt IM, Cooke A.

Clin Exp Immunol. 1988 Oct;74(1):63-7.

50.

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