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Items: 9

1.

Understanding the Dynamics of T-Cell Activation in Health and Disease Through the Lens of Computational Modeling.

Rohrs JA, Wang P, Finley SD.

JCO Clin Cancer Inform. 2019 Jan;3:1-8. doi: 10.1200/CCI.18.00057.

2.

Computational Model of Chimeric Antigen Receptors Explains Site-Specific Phosphorylation Kinetics.

Rohrs JA, Zheng D, Graham NA, Wang P, Finley SD.

Biophys J. 2018 Sep 18;115(6):1116-1129. doi: 10.1016/j.bpj.2018.08.018. Epub 2018 Aug 22.

3.

CAR-T Cells Surface-Engineered with Drug-Encapsulated Nanoparticles Can Ameliorate Intratumoral T-cell Hypofunction.

Siriwon N, Kim YJ, Siegler E, Chen X, Rohrs JA, Liu Y, Wang P.

Cancer Immunol Res. 2018 Jul;6(7):812-824. doi: 10.1158/2326-6066.CIR-17-0502. Epub 2018 May 2.

PMID:
29720380
4.

In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia.

Cheng Z, Wei R, Ma Q, Shi L, He F, Shi Z, Jin T, Xie R, Wei B, Chen J, Fang H, Han X, Rohrs JA, Bryson P, Liu Y, Li QJ, Zhu B, Wang P.

Mol Ther. 2018 Apr 4;26(4):976-985. doi: 10.1016/j.ymthe.2018.01.022. Epub 2018 Feb 2.

PMID:
29503204
5.

Combination drug delivery via multilamellar vesicles enables targeting of tumor cells and tumor vasculature.

Liu Y, Kim YJ, Siriwon N, Rohrs JA, Yu Z, Wanga P.

Biotechnol Bioeng. 2018 Jun;115(6):1403-1415. doi: 10.1002/bit.26566. Epub 2018 Mar 6.

PMID:
29457630
6.

Combination Cancer Therapy Using Chimeric Antigen Receptor-Engineered Natural Killer Cells as Drug Carriers.

Siegler EL, Kim YJ, Chen X, Siriwon N, Mac J, Rohrs JA, Bryson PD, Wang P.

Mol Ther. 2017 Dec 6;25(12):2607-2619. doi: 10.1016/j.ymthe.2017.08.010. Epub 2017 Aug 19.

7.

Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation.

Rohrs JA, Wang P, Finley SD.

Cell Mol Bioeng. 2016;9:351-367. Epub 2016 Apr 26.

8.

Predictive model of thrombospondin-1 and vascular endothelial growth factor in breast tumor tissue.

Rohrs JA, Sulistio CD, Finley SD.

NPJ Syst Biol Appl. 2016;2. pii: 16030. doi: 10.1038/npjsba.2016.30. Epub 2016 Oct 20.

9.

Generation of Targeted Adeno-Associated Virus (AAV) Vectors for Human Gene Therapy.

Liu Y, Siriwon N, Rohrs JA, Wang P.

Curr Pharm Des. 2015;21(22):3248-56. Review.

PMID:
26027561

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