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Items: 1 to 50 of 61

1.

A history of undescended testes in young men with Klinefelter syndrome does not reduce the chances for successful microsurgical testicular sperm extraction.

Ragab MW, Cremers JF, Zitzmann M, Nieschlag E, Kliesch S, Rohayem J.

Andrology. 2018 Jul;6(4):525-531. doi: 10.1111/andr.12503. Epub 2018 Jun 21.

2.

Gonadal function in adult male patients with congenital adrenal hyperplasia.

Engels M, Gehrmann K, Falhammar H, Webb EA, Nordenström A, Sweep FC, Span PN, van Herwaarden AE, Rohayem J, Richter-Unruh A, Bouvattier C, Köhler B, Kortmann BB, Arlt W, Roeleveld N, Reisch N, Stikkelbroeck NMML, Claahsen-van der Grinten HL; dsd-LIFE group.

Eur J Endocrinol. 2018 Mar;178(3):285-294. doi: 10.1530/EJE-17-0862. Epub 2018 Jan 16.

PMID:
29339528
3.

Monogenic diabetes syndromes: Locus-specific databases for Alström, Wolfram, and Thiamine-responsive megaloblastic anemia.

Astuti D, Sabir A, Fulton P, Zatyka M, Williams D, Hardy C, Milan G, Favaretto F, Yu-Wai-Man P, Rohayem J, López de Heredia M, Hershey T, Tranebjaerg L, Chen JH, Chaussenot A, Nunes V, Marshall B, McAfferty S, Tillmann V, Maffei P, Paquis-Flucklinger V, Geberhiwot T, Mlynarski W, Parkinson K, Picard V, Bueno GE, Dias R, Arnold A, Richens C, Paisey R, Urano F, Semple R, Sinnott R, Barrett TG.

Hum Mutat. 2017 Jul;38(7):764-777. doi: 10.1002/humu.23233. Epub 2017 Jun 1.

4.

Impact of various progestins with or without transdermal testosterone on gonadotropin levels for non-invasive hormonal male contraception: a randomized clinical trial.

Zitzmann M, Rohayem J, Raidt J, Kliesch S, Kumar N, Sitruk-Ware R, Nieschlag E.

Andrology. 2017 May;5(3):516-526. doi: 10.1111/andr.12328. Epub 2017 Feb 11.

5.

Delayed treatment of undescended testes may promote hypogonadism and infertility.

Rohayem J, Luberto A, Nieschlag E, Zitzmann M, Kliesch S.

Endocrine. 2017 Mar;55(3):914-924. doi: 10.1007/s12020-016-1178-0. Epub 2017 Jan 9.

PMID:
28070708
6.

Testicular function during puberty and young adulthood in patients with Klinefelter's syndrome with and without spermatozoa in seminal fluid.

Rohayem J, Nieschlag E, Zitzmann M, Kliesch S.

Andrology. 2016 Nov;4(6):1178-1186. doi: 10.1111/andr.12249. Epub 2016 Sep 9.

8.

Testicular growth and spermatogenesis: new goals for pubertal hormone replacement in boys with hypogonadotropic hypogonadism? -a multicentre prospective study of hCG/rFSH treatment outcomes during adolescence.

Rohayem J, Hauffa BP, Zacharin M, Kliesch S, Zitzmann M; “German Adolescent Hypogonadotropic Hypogonadism Study Group”.

Clin Endocrinol (Oxf). 2017 Jan;86(1):75-87. doi: 10.1111/cen.13164. Epub 2016 Sep 7.

PMID:
27467188
9.

Causes of hypogonadotropic hypogonadism predict response to gonadotropin substitution in adults.

Rohayem J, Sinthofen N, Nieschlag E, Kliesch S, Zitzmann M.

Andrology. 2016 Jan;4(1):87-94. doi: 10.1111/andr.12128.

10.

Suicide Risk of Heroin Dependent Subjects in Lebanon.

Kazour F, Soufia M, Rohayem J, Richa S.

Community Ment Health J. 2016 Jul;52(5):589-96. doi: 10.1007/s10597-015-9952-7. Epub 2015 Sep 30.

PMID:
26424734
11.

Inhibin B, AMH, but not INSL3, IGF1 or DHEAS support differentiation between constitutional delay of growth and puberty and hypogonadotropic hypogonadism.

Rohayem J, Nieschlag E, Kliesch S, Zitzmann M.

Andrology. 2015 Sep;3(5):882-7. doi: 10.1111/andr.12088. Epub 2015 Aug 12.

12.

Age and markers of Leydig cell function, but not of Sertoli cell function predict the success of sperm retrieval in adolescents and adults with Klinefelter's syndrome.

Rohayem J, Fricke R, Czeloth K, Mallidis C, Wistuba J, Krallmann C, Zitzmann M, Kliesch S.

Andrology. 2015 Sep;3(5):868-75. doi: 10.1111/andr.12067. Epub 2015 Jul 31.

13.

Klinefelter-Syndrom - Ergebnisse nach Mikro-TESE und ICSI.

Ruchalla E, Rohayem J, Kliesch S.

Aktuelle Urol. 2015 Mar;46(2):93-4. doi: 10.1055/s-0035-1549202. Epub 2015 Apr 21. German. No abstract available.

PMID:
25897524
14.

Effects of adolescence-onset hypogonadism on metabolism, bone mineral density and quality of life in adulthood.

Tam FI, Huebner A, Hofbauer LC, Rohayem J.

J Pediatr Endocrinol Metab. 2015 Sep;28(9-10):1047-55. doi: 10.1515/jpem-2015-0005.

PMID:
25894640
15.

Early identification of women at risk of postpartum depression using the Edinburgh Postnatal Depression Scale (EPDS) in a sample of Lebanese women.

El-Hachem C, Rohayem J, Bou Khalil R, Richa S, Kesrouani A, Gemayel R, Aouad N, Hatab N, Zaccak E, Yaghi N, Salameh S, Attieh E.

BMC Psychiatry. 2014 Sep 7;14:242. doi: 10.1186/s12888-014-0242-7.

16.

Hypogonadismus--Anabolikamissbrauch ist häufige Ursache.

Rohayem J.

Aktuelle Urol. 2014 Jul;45(4):256-8. doi: 10.1055/s-0034-1389223. Epub 2014 Aug 28. German. No abstract available.

PMID:
25166598
17.

Prevalence and correlates of alcohol abuse and dependence in Lebanon: results from the Lebanese Epidemiologic Survey on Alcohol (LESA).

Yazbek JC, Haddad R, Bou Khalil R, Hlais S, Rizk GA, Rohayem J, Richa S.

J Addict Dis. 2014;33(3):221-33. doi: 10.1080/10550887.2014.950026.

PMID:
25115340
18.

PPNDS inhibits murine Norovirus RNA-dependent RNA-polymerase mimicking two RNA stacking bases.

Croci R, Tarantino D, Milani M, Pezzullo M, Rohayem J, Bolognesi M, Mastrangelo E.

FEBS Lett. 2014 May 2;588(9):1720-5. doi: 10.1016/j.febslet.2014.03.021. Epub 2014 Mar 18.

19.

Structural bases of norovirus RNA dependent RNA polymerase inhibition by novel suramin-related compounds.

Croci R, Pezzullo M, Tarantino D, Milani M, Tsay SC, Sureshbabu R, Tsai YJ, Mastrangelo E, Rohayem J, Bolognesi M, Hwu JR.

PLoS One. 2014 Mar 12;9(3):e91765. doi: 10.1371/journal.pone.0091765. eCollection 2014.

20.

Delivery of suramin as an antiviral agent through liposomal systems.

Mastrangelo E, Mazzitelli S, Fabbri J, Rohayem J, Ruokolainen J, Nykänen A, Milani M, Pezzullo M, Nastruzzi C, Bolognesi M.

ChemMedChem. 2014 May;9(5):933-9. doi: 10.1002/cmdc.201300563. Epub 2014 Mar 11.

PMID:
24616282
21.

Activation of dendritic cells by the novel Toll-like receptor 3 agonist RGC100.

Naumann K, Wehner R, Schwarze A, Petzold C, Schmitz M, Rohayem J.

Clin Dev Immunol. 2013;2013:283649. doi: 10.1155/2013/283649. Epub 2013 Dec 2.

22.

Restoration of fertility by gonadotropin replacement in a man with hypogonadotropic azoospermia and testicular adrenal rest tumors due to untreated simple virilizing congenital adrenal hyperplasia.

Rohayem J, Tüttelmann F, Mallidis C, Nieschlag E, Kliesch S, Zitzmann M.

Eur J Endocrinol. 2014 Mar 13;170(4):K11-7. doi: 10.1530/EJE-13-0449. Print 2014 Apr.

PMID:
24394723
23.

Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.

Tarantino D, Pezzullo M, Mastrangelo E, Croci R, Rohayem J, Robel I, Bolognesi M, Milani M.

Antiviral Res. 2014 Feb;102:23-8. doi: 10.1016/j.antiviral.2013.11.016. Epub 2013 Dec 4.

24.

EURO-WABB: an EU rare diseases registry for Wolfram syndrome, Alström syndrome and Bardet-Biedl syndrome.

Farmer A, Aymé S, de Heredia ML, Maffei P, McCafferty S, Młynarski W, Nunes V, Parkinson K, Paquis-Flucklinger V, Rohayem J, Sinnott R, Tillmann V, Tranebjaerg L, Barrett TG.

BMC Pediatr. 2013 Aug 27;13:130. doi: 10.1186/1471-2431-13-130.

25.

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

Barral K, Sallamand C, Petzold C, Coutard B, Collet A, Thillier Y, Zimmermann J, Vasseur JJ, Canard B, Rohayem J, Debart F, Decroly E.

Antiviral Res. 2013 Sep;99(3):292-300. doi: 10.1016/j.antiviral.2013.06.001. Epub 2013 Jun 12.

PMID:
23769894
26.

TLR7/8 agonists trigger immunostimulatory properties of human 6-sulfo LacNAc dendritic cells.

Jähnisch H, Wehner R, Tunger A, Kunze A, Oehrl S, Schäkel K, Rohayem J, Bornhäuser M, Tonn T, Bachmann M, Schmitz M.

Cancer Lett. 2013 Jul 10;335(1):119-27. doi: 10.1016/j.canlet.2013.02.003. Epub 2013 Feb 9.

PMID:
23402811
27.

Metabolic syndrome (MetS) in Lebanese patients with schizophrenia receiving atypical antipsychotic drugs.

Bou Khalil R, Rohayem J, Abou Said N, El Chammay R, Haddad R, Richa S.

Asian J Psychiatr. 2013 Feb;6(1):88-9. doi: 10.1016/j.ajp.2012.08.005. Epub 2012 Aug 29. No abstract available.

PMID:
23380330
28.

Modification of small interfering RNAs to prevent off-target effects by the sense strand.

Nolte A, Ott K, Rohayem J, Walker T, Schlensak C, Wendel HP.

N Biotechnol. 2013 Jan 25;30(2):159-65. doi: 10.1016/j.nbt.2012.10.001. Epub 2012 Nov 1.

PMID:
23124048
29.

ADHD prevalence in Lebanese school-age population.

Richa S, Rohayem J, Chammai R, Kazour F, Haddad R, Hleis S, Alameddine A, Gerbaka B.

J Atten Disord. 2014 Apr;18(3):242-6. doi: 10.1177/1087054712445065. Epub 2012 May 24.

PMID:
22628148
30.

[Androgen deprivation therapy in prostate cancer. Indication and systemic consequences].

Rohayem J, Kliesch S.

Urologe A. 2012 Apr;51(4):557-64; quiz 565-6. doi: 10.1007/s00120-012-2808-7. German.

PMID:
22476802
31.

Structure-based inhibition of Norovirus RNA-dependent RNA polymerases.

Mastrangelo E, Pezzullo M, Tarantino D, Petazzi R, Germani F, Kramer D, Robel I, Rohayem J, Bolognesi M, Milani M.

J Mol Biol. 2012 Jun 8;419(3-4):198-210. doi: 10.1016/j.jmb.2012.03.008. Epub 2012 Mar 21.

PMID:
22446684
32.

Diabetes and neurodegeneration in Wolfram syndrome: a multicenter study of phenotype and genotype.

Rohayem J, Ehlers C, Wiedemann B, Holl R, Oexle K, Kordonouri O, Salzano G, Meissner T, Burger W, Schober E, Huebner A, Lee-Kirsch MA; Wolfram Syndrome Diabetes Writing Group.

Diabetes Care. 2011 Jul;34(7):1503-10. doi: 10.2337/dc10-1937. Epub 2011 May 20.

33.

[Awareness and knowledge about risks of drinking during pregnancy in pregnant Lebanese women].

Maalouf D, El Hachem H, Kesrouani A, Hleis S, Rohayem J, Chammai R, Haddad G, Haddad R, Richa S.

Encephale. 2011 Apr;37(2):94-100. doi: 10.1016/j.encep.2010.04.015. Epub 2010 Jul 1. French.

PMID:
21482226
34.

Antiviral strategies to control calicivirus infections.

Rohayem J, Bergmann M, Gebhardt J, Gould E, Tucker P, Mattevi A, Unge T, Hilgenfeld R, Neyts J.

Antiviral Res. 2010 Aug;87(2):162-78. doi: 10.1016/j.antiviral.2010.05.002. Epub 2010 May 21. Review.

PMID:
20471996
35.

Norovirus seasonality and the potential impact of climate change.

Rohayem J.

Clin Microbiol Infect. 2009 Jun;15(6):524-7. doi: 10.1111/j.1469-0691.2009.02846.x. Review.

36.

Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 A resolution.

Speroni S, Rohayem J, Nenci S, Bonivento D, Robel I, Barthel J, Luzhkov VB, Coutard B, Canard B, Mattevi A.

J Mol Biol. 2009 Apr 17;387(5):1137-52. doi: 10.1016/j.jmb.2009.02.044. Epub 2009 Feb 26.

PMID:
19249313
37.

The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity.

Högbom M, Jäger K, Robel I, Unge T, Rohayem J.

J Gen Virol. 2009 Feb;90(Pt 2):281-91. doi: 10.1099/vir.0.005629-0.

PMID:
19141436
38.

Detection of herpesvirus and adenovirus co-infections with diagnostic DNA-microarrays.

Müller R, Ditzen A, Hille K, Stichling M, Ehricht R, Illmer T, Ehninger G, Rohayem J.

J Virol Methods. 2009 Feb;155(2):161-6. doi: 10.1016/j.jviromet.2008.10.014. Epub 2008 Dec 2.

PMID:
19022297
39.

[Predictors of prophylactic response to lithium].

Rohayem J, Baylé JF, Richa S.

Encephale. 2008 Sep;34(4):394-9. doi: 10.1016/j.encep.2007.05.002. Epub 2007 Nov 26. Review. French.

PMID:
18922242
40.

Functional characterization of the cleavage specificity of the sapovirus chymotrypsin-like protease.

Robel I, Gebhardt J, Mesters JR, Gorbalenya A, Coutard B, Canard B, Hilgenfeld R, Rohayem J.

J Virol. 2008 Aug;82(16):8085-93. doi: 10.1128/JVI.00693-08. Epub 2008 Jun 11.

41.

The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C.

De Palma AM, Heggermont W, Lanke K, Coutard B, Bergmann M, Monforte AM, Canard B, De Clercq E, Chimirri A, Pürstinger G, Rohayem J, van Kuppeveld F, Neyts J.

J Virol. 2008 May;82(10):4720-30. doi: 10.1128/JVI.01338-07. Epub 2008 Mar 12.

42.

Chlorpromazine combined with cidofovir for treatment of a patient suffering from progressive multifocal leukoencephalopathy.

Pöhlmann C, Hochauf K, Röllig C, Schetelig J, Wunderlich O, Bandt D, Ehninger G, Jacobs E, Rohayem J.

Intervirology. 2007;50(6):412-7. doi: 10.1159/000112916. Epub 2008 Jan 8.

PMID:
18182774
43.

The VIZIER project: preparedness against pathogenic RNA viruses.

Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B.

Antiviral Res. 2008 Apr;78(1):37-46. Epub 2007 Nov 29.

PMID:
18083241
44.

Differential cleavage of the norovirus polyprotein precursor by two active forms of the viral protease.

Scheffler U, Rudolph W, Gebhardt J, Rohayem J.

J Gen Virol. 2007 Jul;88(Pt 7):2013-8.

PMID:
17554035
45.

Cidofovir and foscarnet for treatment of human herpesvirus 6 encephalitis in a neutropenic stem cell transplant recipient.

Pöhlmann C, Schetelig J, Reuner U, Bornhäuser M, Illmer T, Kiani A, Ehninger G, Jacobs E, Rohayem J.

Clin Infect Dis. 2007 Jun 15;44(12):e118-20. Epub 2007 May 2.

PMID:
17516391
46.

Structural and functional characterization of sapovirus RNA-dependent RNA polymerase.

Fullerton SW, Blaschke M, Coutard B, Gebhardt J, Gorbalenya A, Canard B, Tucker PA, Rohayem J.

J Virol. 2007 Feb;81(4):1858-71. Epub 2006 Nov 22.

47.

Detection of beta-herpesviruses in allogenic stem cell recipients by quantitative real-time PCR.

Sassenscheidt J, Rohayem J, Illmer T, Bandt D.

J Virol Methods. 2006 Dec;138(1-2):40-8. Epub 2006 Sep 7.

PMID:
16956672
48.

Assessing the risk of transmission of viral diseases in flooded areas: viral load of the River Elbe in Dresden during the flood of August 2002.

Rohayem J, Dumke R, Jaeger K, Schröter-Bobsin U, Mogel M, Kruse A, Jacobs E, Rethwilm A.

Intervirology. 2006;49(6):370-6. Epub 2006 Aug 21.

PMID:
16926550
49.

Characterization of norovirus 3Dpol RNA-dependent RNA polymerase activity and initiation of RNA synthesis.

Rohayem J, Jäger K, Robel I, Scheffler U, Temme A, Rudolph W.

J Gen Virol. 2006 Sep;87(Pt 9):2621-30.

PMID:
16894201
50.

Protein-primed and de novo initiation of RNA synthesis by norovirus 3Dpol.

Rohayem J, Robel I, Jäger K, Scheffler U, Rudolph W.

J Virol. 2006 Jul;80(14):7060-9.

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