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Items: 11

1.

Bioactivation of napabucasin triggers reactive oxygen species-mediated cancer cell death.

Froeling FEM, Mosur Swamynathan M, DeschĂȘnes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito MS, Li J, Chang AY, Trotman LC, Belleau P, Park Y, Rogoff HA, Watson JD, Tuveson DA.

Clin Cancer Res. 2019 Sep 16. pii: clincanres.0302.2019. doi: 10.1158/1078-0432.CCR-19-0302. [Epub ahead of print]

PMID:
31527169
2.

Evaluation of Tumor Cell-Tumor Microenvironment Component Interactions as Potential Predictors of Patient Response to Napabucasin.

Chang AY, Hsu E, Patel J, Li Y, Zhang M, Iguchi H, Rogoff HA.

Mol Cancer Res. 2019 Jul;17(7):1429-1434. doi: 10.1158/1541-7786.MCR-18-1242. Epub 2019 May 1.

PMID:
31043490
3.

Suppression of cancer relapse and metastasis by inhibiting cancer stemness.

Li Y, Rogoff HA, Keates S, Gao Y, Murikipudi S, Mikule K, Leggett D, Li W, Pardee AB, Li CJ.

Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1839-44. doi: 10.1073/pnas.1424171112. Epub 2015 Jan 20.

4.

Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced nonspecific effects.

Chang CI, Yoo JW, Hong SW, Lee SE, Kang HS, Sun X, Rogoff HA, Ban C, Kim S, Li CJ, Lee DK.

Mol Ther. 2009 Apr;17(4):725-32. doi: 10.1038/mt.2008.298. Epub 2009 Jan 20.

5.

Asymmetric RNA duplexes mediate RNA interference in mammalian cells.

Sun X, Rogoff HA, Li CJ.

Nat Biotechnol. 2008 Dec;26(12):1379-82. doi: 10.1038/nbt.1512. Epub 2008 Nov 23. Erratum in: Nat Biotechnol. 2009 Feb;27(2):205.

PMID:
19029911
6.

E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts.

Frame FM, Rogoff HA, Pickering MT, Cress WD, Kowalik TF.

Oncogene. 2006 Jun 1;25(23):3258-66. Epub 2006 Jan 23.

PMID:
16434972
7.

Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response.

Castillo JP, Frame FM, Rogoff HA, Pickering MT, Yurochko AD, Kowalik TF.

J Virol. 2005 Sep;79(17):11467-75.

8.
9.

Life, death and E2F: linking proliferation control and DNA damage signaling via E2F1.

Rogoff HA, Kowalik TF.

Cell Cycle. 2004 Jul;3(7):845-6. Epub 2004 Jul 14. Review.

PMID:
15190206
10.

Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.

Rogoff HA, Pickering MT, Frame FM, Debatis ME, Sanchez Y, Jones S, Kowalik TF.

Mol Cell Biol. 2004 Apr;24(7):2968-77.

11.

E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis.

Rogoff HA, Pickering MT, Debatis ME, Jones S, Kowalik TF.

Mol Cell Biol. 2002 Aug;22(15):5308-18.

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