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Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori PK/PD target attainments in individual patients.

Boidin C, Bourguignon L, Cohen S, Roger C, Lefrant JY, Roberts JA, Allaouchiche B, Lepape A, Friggeri A, Goutelle S.

Antimicrob Agents Chemother. 2019 Sep 3. pii: AAC.00993-19. doi: 10.1128/AAC.00993-19. [Epub ahead of print]


Severe Guillain-Barré syndrome associated with chronic active hepatitis C and mixed cryoglobulinemia: a case report.

Chlilek A, Roger C, Muller L, Carles MJ, Stephan R, Laureillard D, Lavigne JP, Lefrant JY, Sotto A.

BMC Infect Dis. 2019 Jul 17;19(1):636. doi: 10.1186/s12879-019-4278-7.


Assessment of mineral and bone biomarkers highlights a high frequency of hypercalciuria in asymptomatic healthy teenagers.

Bacchetta J, Ginhoux T, Bernoux D, Dubourg L, Ranchin B, Roger C.

Acta Paediatr. 2019 Jun 18. doi: 10.1111/apa.14907. [Epub ahead of print]


Factors associated with hospital stay length, discharge destination, and 30-day readmission rate after primary hip or knee arthroplasty: Retrospective Cohort Study.

Roger C, Debuyzer E, Dehl M, Bulaïd Y, Lamrani A, Havet E, Mertl P.

Orthop Traumatol Surg Res. 2019 Sep;105(5):949-955. doi: 10.1016/j.otsr.2019.04.012. Epub 2019 Jun 15. Review.


Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study.

Roger C, Zieleskiewicz L, Demattei C, Lakhal K, Piton G, Louart B, Constantin JM, Chabanne R, Faure JS, Mahjoub Y, Desmeulles I, Quintard H, Lefrant JY, Muller L; AzuRea Group.

Crit Care. 2019 May 16;23(1):179. doi: 10.1186/s13054-019-2448-z.


Optimization of the treatment with beta-lactam antibiotics in critically ill patients-guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique-SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie et Réanimation-SFAR).

Guilhaumou R, Benaboud S, Bennis Y, Dahyot-Fizelier C, Dailly E, Gandia P, Goutelle S, Lefeuvre S, Mongardon N, Roger C, Scala-Bertola J, Lemaitre F, Garnier M.

Crit Care. 2019 Mar 29;23(1):104. doi: 10.1186/s13054-019-2378-9. Review.


Ultrasound guidance in difficult radial artery puncture for blood gas analysis: A prospective, randomized controlled trial.

Genre Grandpierre R, Bobbia X, Muller L, Markarian T, Occéan BV, Pommet S, Roger C, Lefrant JY, de la Coussaye JE, Claret PG.

PLoS One. 2019 Mar 20;14(3):e0213683. doi: 10.1371/journal.pone.0213683. eCollection 2019.


Milk A1 β-casein and health-related outcomes in humans: a systematic review.

Küllenberg de Gaudry D, Lohner S, Schmucker C, Kapp P, Motschall E, Hörrlein S, Röger C, Meerpohl JJ.

Nutr Rev. 2019 May 1;77(5):278-306. doi: 10.1093/nutrit/nuy063.


Personalized antibiotic dosing for the critically ill.

Roberts JA, Roger C, De Waele JJ.

Intensive Care Med. 2019 May;45(5):715-718. doi: 10.1007/s00134-019-05522-3. Epub 2019 Jan 14. No abstract available.


Microbial contamination and tissue procurement location: A conventional operating room is not mandatory. An observational study.

Louart B, Charles C, Nguyen TL, Builles N, Roger C, Lefrant JY, Vachiery-Lahaye F, De Vos J, Couderc G, Muller L.

PLoS One. 2019 Jan 8;14(1):e0210140. doi: 10.1371/journal.pone.0210140. eCollection 2019.


Temporal Metacognition as the Decoding of Self-Generated Brain Dynamics.

Kononowicz TW, Roger C, van Wassenhove V.

Cereb Cortex. 2019 Sep 13;29(10):4366-4380. doi: 10.1093/cercor/bhy318.


Urinary albumin measurement methods.

Benz-de Bretagne I, Roger C, Carlier MC; groupe de travail SFBC, SFNDT, SNP.

Ann Biol Clin (Paris). 2018 Dec 1;76(6):633-637. doi: 10.1684/abc.2018.1390.


Pocket-sized ultrasound device for internal jugular puncture: A randomized study of performance on a simulation model.

Chetioui A, Masia T, Claret PG, Markarian T, Muller L, Lefrant JY, de La Coussaye JE, Roger C, Bobbia X.

J Vasc Access. 2019 Jul;20(4):404-408. doi: 10.1177/1129729818812733. Epub 2018 Nov 20.


Outcomes and risk factors of transfusion-associated circulatory overload: a case control study.

Daurat A, Grenie J, Roger C, Daurat G, Cuvillon P, Muller L, Lefrant JY.

Transfusion. 2019 Jan;59(1):191-195. doi: 10.1111/trf.15040. Epub 2018 Nov 20.


Understanding the impact of pathophysiological alterations during critical illness on drug pharmacokinetics.

Jamal JA, Roger C, Roberts JA.

Anaesth Crit Care Pain Med. 2018 Dec;37(6):515-517. doi: 10.1016/j.accpm.2018.10.006. Epub 2018 Oct 22. No abstract available.


Lawnmower accidents involving children: Characteristics and suggested preventive measures.

Klein C, Plancq MC, Deroussen F, Roger C, Haraux E, Gouron R.

Arch Pediatr. 2018 Nov;25(8):493-494. doi: 10.1016/j.arcped.2018.09.004. Epub 2018 Oct 16.


Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis.

Barbar SD, Clere-Jehl R, Bourredjem A, Hernu R, Montini F, Bruyère R, Lebert C, Bohé J, Badie J, Eraldi JP, Rigaud JP, Levy B, Siami S, Louis G, Bouadma L, Constantin JM, Mercier E, Klouche K, du Cheyron D, Piton G, Annane D, Jaber S, van der Linden T, Blasco G, Mira JP, Schwebel C, Chimot L, Guiot P, Nay MA, Meziani F, Helms J, Roger C, Louart B, Trusson R, Dargent A, Binquet C, Quenot JP; IDEAL-ICU Trial Investigators and the CRICS TRIGGERSEP Network.

N Engl J Med. 2018 Oct 11;379(15):1431-1442. doi: 10.1056/NEJMoa1803213.


A New Echocardiographic Tool for Cardiac Output Evaluation: An Experimental Study.

Bobbia X, Muller L, Claret PG, Vigouroux L, Perez-Martin A, de La Coussaye JE, Lefrant JY, Louart G, Roger C, Markarian T.

Shock. 2019 Oct;52(4):449-455. doi: 10.1097/SHK.0000000000001273.


Acute liver failure and misdiagnosis: Do not forget viral hepatitis E.

Laumon T, Dietrich H, Muller L, Roger C.

Anaesth Crit Care Pain Med. 2019 Feb;38(1):73-75. doi: 10.1016/j.accpm.2018.06.001. Epub 2018 Jul 11. No abstract available.


Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients.

Bukkems LH, Roger C, Hodiamont CJ, Lefrant JY, Juffermans NP, Roberts JA, van Hest RM.

Int J Antimicrob Agents. 2018 Aug;52(2):218-225. doi: 10.1016/j.ijantimicag.2018.04.016. Epub 2018 Apr 26.


Compression with a pocket-sized ultrasound device to diagnose proximal deep vein thrombosis.

Pujol S, Laurent J, Markarian T, Claret PG, Lefrant JY, Roger C, Muller L, de La Coussaye JE, Perez-Martin A, Bobbia X.

Am J Emerg Med. 2018 Jul;36(7):1262-1264. doi: 10.1016/j.ajem.2018.03.076. Epub 2018 Apr 3.


Assessment of five different probes for lung ultrasound in critically ill patients: A pilot study.

Bobbia X, Chabannon M, Chevallier T, de La Coussaye JE, Lefrant JY, Pujol S, Claret PG, Zieleskiewicz L, Roger C, Muller L.

Am J Emerg Med. 2018 Jul;36(7):1265-1269. doi: 10.1016/j.ajem.2018.03.077. Epub 2018 Apr 3.


A Novel C-Terminal Mutation in Gsdma3 (C+/H-) Leads to Alopecia and Corneal Inflammatory Response in Mice.

Swirski S, Röger C, Pienkowska-Schelling A, Ihlenburg C, Fischer G, May O, Vorm M, Owczarek-Lipska M, Neidhardt J.

Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):561-571. doi: 10.1167/iovs.17-22658.


Integration of lung ultrasound in the diagnostic reasoning in acute dyspneic patients: A prospective randomized study.

Pontis E, Claret PG, Markarian T, Javaudin F, Flacher A, Roger C, Muller L, de La Coussaye JE, Bobbia X.

Am J Emerg Med. 2018 Sep;36(9):1597-1602. doi: 10.1016/j.ajem.2018.01.041. Epub 2018 Jan 31.


Adiponectin attenuates profibrotic extracellular matrix remodeling following cardiac injury by up-regulating matrix metalloproteinase 9 expression in mice.

Jenke A, Schur R, Röger C, Karadeniz Z, Grüger M, Holzhauser L, Savvatis K, Poller W, Schultheiss HP, Landmesser U, Skurk C.

Physiol Rep. 2017 Dec;5(24). pii: e13523. doi: 10.14814/phy2.13523.


Impact of Quality Bundle Enforcement by a Critical Care Pharmacist on Patient Outcome and Costs.

Leguelinel-Blache G, Nguyen TL, Louart B, Poujol H, Lavigne JP, Roberts JA, Muller L, Kinowski JM, Roger C, Lefrant JY.

Crit Care Med. 2018 Feb;46(2):199-207. doi: 10.1097/CCM.0000000000002827.


Multidrug and vancomycin resistance among clinical isolates of Staphylococcus aureus from different teaching hospitals in Nigeria.

Olufunmiso O, Tolulope I, Roger C.

Afr Health Sci. 2017 Sep;17(3):797-807. doi: 10.4314/ahs.v17i3.23.


Clinical Pharmacokinetics and Pharmacodynamics of Oxazolidinones.

Roger C, Roberts JA, Muller L.

Clin Pharmacokinet. 2018 May;57(5):559-575. doi: 10.1007/s40262-017-0601-x. Review.


Immediate interruption of sedation compared with usual sedation care in critically ill postoperative patients (SOS-Ventilation): a randomised, parallel-group clinical trial.

Chanques G, Conseil M, Roger C, Constantin JM, Prades A, Carr J, Muller L, Jung B, Belafia F, Cissé M, Delay JM, de Jong A, Lefrant JY, Futier E, Mercier G, Molinari N, Jaber S; SOS-Ventilation study investigators.

Lancet Respir Med. 2017 Oct;5(10):795-805. doi: 10.1016/S2213-2600(17)30304-1. Epub 2017 Sep 18.


Metal-Based Diversity for Crystalline Metal-Fullerene Frameworks.

Kraft A, Roger C, Schmidt D, Stangl J, Müller-Buschbaum K, Beuerle F.

Chemistry. 2017 Nov 13;23(63):15864-15868. doi: 10.1002/chem.201703709. Epub 2017 Oct 10.


Changes in the distribution of colonising and infecting Candida spp. isolates, antifungal drug consumption and susceptibility in a French intensive care unit: A 10-year study.

Sasso M, Roger C, Sasso M, Poujol H, Barbar S, Lefrant JY, Lachaud L.

Mycoses. 2017 Dec;60(12):770-780. doi: 10.1111/myc.12661. Epub 2017 Jul 31.


Lung real time three-dimensional imaging in critically ill ventilated patients: a global diagnosis concordance study.

Le Goff JM, Roger C, Louart B, Claret PG, Daurat A, Bulyez S, Lefrant JY, Bobbia X, Muller L.

J Clin Monit Comput. 2018 Jun;32(3):513-518. doi: 10.1007/s10877-017-0042-y. Epub 2017 Jul 14.


Impact of renal replacement modalities on the clearance of piperacillin-tazobactam administered via continuous infusion in critically ill patients.

Roger C, Cotta MO, Muller L, Wallis SC, Lipman J, Lefrant JY, Roberts JA.

Int J Antimicrob Agents. 2017 Aug;50(2):227-231. doi: 10.1016/j.ijantimicag.2017.03.018. Epub 2017 Jul 6.


An LC-MS/MS method to determine vancomycin in plasma (total and unbound), urine and renal replacement therapy effluent.

Parker SL, Guerra Valero YC, Ordóñez Mejia JL, Roger C, Lipman J, Roberts JA, Wallis SC.

Bioanalysis. 2017 Jun;9(12):911-924. doi: 10.4155/bio-2017-0019. Epub 2017 Jun 15.


Population Pharmacokinetics of Tigecycline in Critically Ill Patients with Severe Infections.

Xie J, Roberts JA, Alobaid AS, Roger C, Wang Y, Yang Q, Sun J, Dong H, Wang X, Xing J, Lipman J, Dong Y.

Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00345-17. doi: 10.1128/AAC.00345-17. Print 2017 Aug.


Interest of Urinary [TIMP-2] × [IGFBP-7] for Predicting the Occurrence of Acute Kidney Injury After Cardiac Surgery: A Gray Zone Approach.

Finge T, Bertran S, Roger C, Candela D, Pereira B, Scott C, Muller L, Louart B, Lefrant JY.

Anesth Analg. 2017 Sep;125(3):762-769. doi: 10.1213/ANE.0000000000002116.


Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial.

Naik BI, Roger C, Ikeda K, Todorovic MS, Wallis SC, Lipman J, Roberts JA.

Br J Anaesth. 2017 Jun 1;118(6):876-882. doi: 10.1093/bja/aex026.


Rapid emergence of FKS mutations in Candida glabrata isolates in a peritoneal candidiasis.

Sasso M, Roger C, Lachaud L.

Med Mycol Case Rep. 2017 Apr 25;16:28-30. doi: 10.1016/j.mmcr.2017.04.004. eCollection 2017 Jun.


Evaluation of the non-compliance with grouping guidelines which may lead to "wrong blood in tube", an observational study and risk factor analysis.

Daurat A, Boudet E, Daurat G, Roger C, Gris JC, Tunez V, Gaste MC, Lefrant JY.

Transfus Clin Biol. 2017 Jun;24(2):47-51. doi: 10.1016/j.tracli.2017.01.003.


Metformin monotherapy in melanoma: a pilot, open-label, prospective, and multicentric study indicates no benefit.

Montaudié H, Cerezo M, Bahadoran P, Roger C, Passeron T, Machet L, Arnault JP, Verneuil L, Maubec E, Aubin F, Granel F, Giacchero D, Hofman V, Lacour JP, Maryline A, Ballotti R, Rocchi S.

Pigment Cell Melanoma Res. 2017 May;30(3):378-380. doi: 10.1111/pcmr.12576. Epub 2017 Apr 22. No abstract available.


Comparison of different techniques of central venous pressure measurement in mechanically ventilated critically ill patients.

Roger C, Muller L, Riou B, Molinari N, Louart B, Kerbrat H, Teboul JL, Lefrant JY.

Br J Anaesth. 2017 Feb;118(2):223-231. doi: 10.1093/bja/aew386.


Population Pharmacokinetics of Piperacillin in Nonobese, Obese, and Morbidly Obese Critically Ill Patients.

Alobaid AS, Wallis SC, Jarrett P, Starr T, Stuart J, Lassig-Smith M, Mejia JL, Roberts MS, Roger C, Udy AA, Lipman J, Roberts JA.

Antimicrob Agents Chemother. 2017 Feb 23;61(3). pii: e01276-16. doi: 10.1128/AAC.01276-16. Print 2017 Mar.


Caspofungin Population Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-Venous Haemofiltration or Haemodiafiltration.

Roger C, Wallis SC, Muller L, Saissi G, Lipman J, Brüggemann RJ, Lefrant JY, Roberts JA.

Clin Pharmacokinet. 2017 Sep;56(9):1057-1068. doi: 10.1007/s40262-016-0495-z.


The mutation p.E113K in the Schiff base counterion of rhodopsin is associated with two distinct retinal phenotypes within the same family.

Reiff C, Owczarek-Lipska M, Spital G, Röger C, Hinz H, Jüschke C, Thiele H, Altmüller J, Nürnberg P, Da Costa R, Neidhardt J.

Sci Rep. 2016 Nov 4;6:36208. doi: 10.1038/srep36208.


A Novel Method Combining Vitreous Aspiration and Intravitreal AAV2/8 Injection Results in Retina-Wide Transduction in Adult Mice.

Da Costa R, Röger C, Segelken J, Barben M, Grimm C, Neidhardt J.

Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5326-5334. doi: 10.1167/iovs.16-19701.


Occipital nerve stimulation improves the quality of life in medically-intractable chronic cluster headache: Results of an observational prospective study.

Fontaine D, Blond S, Lucas C, Regis J, Donnet A, Derrey S, Guegan-Massardier E, Jarraya B, Dang-Vu B, Bourdain F, Valade D, Roos C, Creach C, Chabardes S, Giraud P, Voirin J, Bloch J, Rocca A, Colnat-Coulbois S, Caire F, Roger C, Romettino S, Lanteri-Minet M.

Cephalalgia. 2017 Oct;37(12):1173-1179. doi: 10.1177/0333102416673206. Epub 2016 Oct 3.


Effect of Obesity on the Population Pharmacokinetics of Fluconazole in Critically Ill Patients.

Alobaid AS, Wallis SC, Jarrett P, Starr T, Stuart J, Lassig-Smith M, Mejia JL, Roberts MS, Sinnollareddy MG, Roger C, Lipman J, Roberts JA.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6550-6557. doi: 10.1128/AAC.01088-16. Print 2016 Nov.


Comparison of the visualisation of the subclavian and axillary veins: An ultrasound study in healthy volunteers.

Roger C, Sadek M, Bastide S, Jeannes P, Muller L, Bobbia X, Lefrant JY.

Anaesth Crit Care Pain Med. 2017 Feb;36(1):65-68. doi: 10.1016/j.accpm.2016.05.007. Epub 2016 Aug 2.


Does the infusion rate of fluid affect rapidity of mean arterial pressure restoration during controlled hemorrhage.

Roger C, Louart B, Louart G, Bobbia X, Claret PG, Perez-Martin A, Muller L, Lefrant JY.

Am J Emerg Med. 2016 Sep;34(9):1743-9. doi: 10.1016/j.ajem.2016.05.019. Epub 2016 May 13.


Influence of Renal Replacement Modalities on Amikacin Population Pharmacokinetics in Critically Ill Patients on Continuous Renal Replacement Therapy.

Roger C, Wallis SC, Muller L, Saissi G, Lipman J, Lefrant JY, Roberts JA.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4901-9. doi: 10.1128/AAC.00828-16. Print 2016 Aug.

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