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Items: 1 to 50 of 277

1.

Diffusion-Weighted MRI Is Insensitive to Changes in the Tumor Microenvironment Induced by Antiangiogenic Therapy.

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK.

Transl Oncol. 2018 Jul 20;11(5):1128-1136. doi: 10.1016/j.tranon.2018.07.005. [Epub ahead of print]

2.

DCE-MRI of Sunitinib-Induced Changes in Tumor Microvasculature and Hypoxia: A Study of Pancreatic Ductal Adenocarcinoma Xenografts.

Wegner CS, Hauge A, Simonsen TG, Gaustad JV, Andersen LMK, Rofstad EK.

Neoplasia. 2018 Jul;20(7):734-744. doi: 10.1016/j.neo.2018.05.006. Epub 2018 Jun 19.

3.

DCE-MRI-Derived Measures of Tumor Hypoxia and Interstitial Fluid Pressure Predict Outcomes in Cervical Carcinoma.

Simonsen TG, Lund KV, Hompland T, Kristensen GB, Rofstad EK.

Int J Radiat Oncol Biol Phys. 2018 Apr 19. pii: S0360-3016(18)30692-8. doi: 10.1016/j.ijrobp.2018.04.035. [Epub ahead of print]

PMID:
29859790
4.

Increasing aggressiveness of patient-derived xenograft models of cervix carcinoma during serial transplantation.

Wegner CS, Hauge A, Andersen LMK, Huang R, Simonsen TG, Gaustad JV, Rofstad EK.

Oncotarget. 2018 Apr 20;9(30):21036-21051. doi: 10.18632/oncotarget.24783. eCollection 2018 Apr 20.

5.

Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma.

Huang R, Rofstad EK.

J Exp Clin Cancer Res. 2018 Apr 27;37(1):92. doi: 10.1186/s13046-018-0763-x. Review.

6.

Diffusion-weighted MRI-derived ADC values reflect collagen I content in PDX models of uterine cervical cancer.

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK.

Oncotarget. 2017 Nov 11;8(62):105682-105691. doi: 10.18632/oncotarget.22388. eCollection 2017 Dec 1.

7.

Vascular abnormalities and development of hypoxia in microscopic melanoma xenografts.

Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK.

J Transl Med. 2017 Nov 28;15(1):241. doi: 10.1186/s12967-017-1347-9.

8.

DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment.

Hauge A, Wegner CS, Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK.

J Transl Med. 2017 Nov 3;15(1):225. doi: 10.1186/s12967-017-1331-4.

9.

Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts.

Huang R, Andersen LMK, Rofstad EK.

J Transl Med. 2017 Oct 10;15(1):203. doi: 10.1186/s12967-017-1307-4.

10.

Dynamic contrast-enhanced MRI of the microenvironment of pancreatic adenocarcinoma xenografts.

Wegner CS, Hauge A, Gaustad JV, Andersen LMK, Simonsen TG, Galappathi K, Rofstad EK.

Acta Oncol. 2017 Dec;56(12):1754-1762. doi: 10.1080/0284186X.2017.1343494. Epub 2017 Jun 29.

PMID:
28661213
11.

Lymph node metastasis and the physicochemical micro-environment of pancreatic ductal adenocarcinoma xenografts.

Andersen LMK, Wegner CS, Simonsen TG, Huang R, Gaustad JV, Hauge A, Galappathi K, Rofstad EK.

Oncotarget. 2017 Jul 18;8(29):48060-48074. doi: 10.18632/oncotarget.18231.

12.

Antiangiogenic agents targeting different angiogenic pathways have opposite effects on tumor hypoxia in R-18 human melanoma xenografts.

Gaustad JV, Simonsen TG, Andersen LMK, Rofstad EK.

BMC Cancer. 2017 Jun 12;17(1):411. doi: 10.1186/s12885-017-3404-4.

13.

Pretreatment late-phase DCE-MRI predicts outcome in locally advanced cervix cancer.

Lund KV, Simonsen TG, Kristensen GB, Rofstad EK.

Acta Oncol. 2017 May;56(5):675-681. doi: 10.1080/0284186X.2017.1294762. Epub 2017 Feb 28.

PMID:
28447564
14.

The Effect of Sunitinib Treatment in Human Melanoma Xenografts: Associations with Angiogenic Profiles.

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK.

Transl Oncol. 2017 Apr;10(2):158-167. doi: 10.1016/j.tranon.2016.12.007. Epub 2017 Feb 3.

15.

Properdistatin inhibits angiogenesis and improves vascular function in human melanoma xenografts with low thrombospondin-1 expression.

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK.

Oncotarget. 2016 Nov 22;7(47):76806-76815. doi: 10.18632/oncotarget.12695.

16.

Functional intratumoral lymphatics in patient-derived xenograft models of squamous cell carcinoma of the uterine cervix: implications for lymph node metastasis.

Rofstad EK, Huang R, Galappathi K, Andersen LM, Wegner CS, Hauge A, Gaustad JV, Simonsen TG.

Oncotarget. 2016 Aug 30;7(35):56986-56997. doi: 10.18632/oncotarget.10931.

17.

Cancer stem cells (CSCs), cervical CSCs and targeted therapies.

Huang R, Rofstad EK.

Oncotarget. 2017 May 23;8(21):35351-35367. doi: 10.18632/oncotarget.10169. Review.

18.

Diffusion-weighted and dynamic contrast-enhanced MRI of pancreatic adenocarcinoma xenografts: associations with tumor differentiation and collagen content.

Wegner CS, Gaustad JV, Andersen LM, Simonsen TG, Rofstad EK.

J Transl Med. 2016 Jun 7;14(1):161. doi: 10.1186/s12967-016-0920-y.

19.

Intracranial Tumor Cell Migration and the Development of Multiple Brain Metastases in Malignant Melanoma.

Simonsen TG, Gaustad JV, Rofstad EK.

Transl Oncol. 2016 Jun;9(3):211-8. doi: 10.1016/j.tranon.2016.04.003. Epub 2016 May 17.

20.

Patient-derived xenograft models of squamous cell carcinoma of the uterine cervix.

Rofstad EK, Simonsen TG, Huang R, Andersen LM, Galappathi K, Ellingsen C, Wegner CS, Hauge A, Gaustad JV.

Cancer Lett. 2016 Apr 10;373(2):147-55. doi: 10.1016/j.canlet.2016.01.047. Epub 2016 Jan 29.

PMID:
26828134
21.

Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases.

Simonsen TG, Gaustad JV, Rofstad EK.

J Exp Clin Cancer Res. 2015 Dec 15;34:150. doi: 10.1186/s13046-015-0264-0.

22.

Identification of Metastasis-Associated Metabolic Profiles of Tumors by (1)H-HR-MAS-MRS.

Gorad SS, Ellingsen C, Bathen TF, Mathiesen BS, Moestue SA, Rofstad EK.

Neoplasia. 2015 Oct;17(10):767-75. doi: 10.1016/j.neo.2015.10.001.

23.

Early effects of low dose bevacizumab treatment assessed by magnetic resonance imaging.

Gaustad JV, Simonsen TG, Smistad R, Wegner CS, Andersen LM, Rofstad EK.

BMC Cancer. 2015 Nov 14;15:900. doi: 10.1186/s12885-015-1918-1.

24.

Hypoxia biomarkers in squamous cell carcinoma of the uterine cervix.

Ellingsen C, Andersen LM, Galappathi K, Rofstad EK.

BMC Cancer. 2015 Oct 26;15:805. doi: 10.1186/s12885-015-1828-2.

25.

Short-term pretreatment DCE-MRI in prediction of outcome in locally advanced cervical cancer.

Lund KV, Simonsen TG, Hompland T, Kristensen GB, Rofstad EK.

Radiother Oncol. 2015 Jun;115(3):379-85. doi: 10.1016/j.radonc.2015.05.001. Epub 2015 May 18.

PMID:
25998804
26.

Peritumoral interstitial fluid flow velocity predicts survival in cervical carcinoma.

Hompland T, Lund KV, Ellingsen C, Kristensen GB, Rofstad EK.

Radiother Oncol. 2014 Oct;113(1):132-8. doi: 10.1016/j.radonc.2014.09.011. Epub 2014 Oct 15.

PMID:
25443501
27.

Tumor interstitial fluid pressure-a link between tumor hypoxia, microvascular density, and lymph node metastasis.

Rofstad EK, Galappathi K, Mathiesen BS.

Neoplasia. 2014 Jul;16(7):586-94. doi: 10.1016/j.neo.2014.07.003.

28.

Thrombospondin-1 domain-containing peptide properdistatin improves vascular function in human melanoma xenografts.

Gaustad JV, Simonsen TG, Andersen LM, Rofstad EK.

Microvasc Res. 2015 Mar;98:159-65. doi: 10.1016/j.mvr.2014.02.005. Epub 2014 Feb 17.

PMID:
24555949
29.

DW-MRI in assessment of the hypoxic fraction, interstitial fluid pressure, and metastatic propensity of melanoma xenografts.

Hompland T, Ellingsen C, Galappathi K, Rofstad EK.

BMC Cancer. 2014 Feb 15;14:92. doi: 10.1186/1471-2407-14-92.

30.

Magnetic resonance imaging identifies early effects of sunitinib treatment in human melanoma xenografts.

Gaustad JV, Pozdniakova V, Hompland T, Simonsen TG, Rofstad EK.

J Exp Clin Cancer Res. 2013 Nov 19;32:93. doi: 10.1186/1756-9966-32-93.

31.

DCE-MRI of the hypoxic fraction, radioresponsiveness, and metastatic propensity of cervical carcinoma xenografts.

Ellingsen C, Hompland T, Galappathi K, Mathiesen B, Rofstad EK.

Radiother Oncol. 2014 Feb;110(2):335-41. doi: 10.1016/j.radonc.2013.10.018. Epub 2013 Nov 11.

PMID:
24231244
32.

The Microenvironment of Cervical Carcinoma Xenografts: Associations with Lymph Node Metastasis and Its Assessment by DCE-MRI.

Ellingsen C, Walenta S, Hompland T, Mueller-Klieser W, Rofstad EK.

Transl Oncol. 2013 Oct 1;6(5):607-17. eCollection 2013.

33.

The efficacy of CHK1 inhibitors is not altered by hypoxia, but is enhanced after reoxygenation.

Hasvold G, Nähse-Kumpf V, Tkacz-Stachowska K, Rofstad EK, Syljuåsen RG.

Mol Cancer Ther. 2013 May;12(5):705-16. doi: 10.1158/1535-7163.MCT-12-0879. Epub 2013 May 1.

34.

Connective tissue of cervical carcinoma xenografts: associations with tumor hypoxia and interstitial fluid pressure and its assessment by DCE-MRI and DW-MRI.

Hompland T, Ellingsen C, Galappathi K, Rofstad EK.

Acta Oncol. 2014 Jan;53(1):6-15. doi: 10.3109/0284186X.2013.773073. Epub 2013 Feb 27.

PMID:
23445339
35.

Preclinical evaluation of Gd-DTPA and gadomelitol as contrast agents in DCE-MRI of cervical carcinoma interstitial fluid pressure.

Hompland T, Ellingsen C, Rofstad EK.

BMC Cancer. 2012 Nov 22;12:544. doi: 10.1186/1471-2407-12-544.

36.

Tumors exposed to acute cyclic hypoxia show increased vessel density and delayed blood supply.

Gaustad JV, Simonsen TG, Roa AM, Rofstad EK.

Microvasc Res. 2013 Jan;85:10-5. doi: 10.1016/j.mvr.2012.11.002. Epub 2012 Nov 12.

PMID:
23154277
37.

Tumor-line specific causes of intertumor heterogeneity in blood supply in human melanoma xenografts.

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK.

Microvasc Res. 2013 Jan;85:16-23. doi: 10.1016/j.mvr.2012.11.001. Epub 2012 Nov 10.

PMID:
23149341
38.

Assessment of the interstitial fluid pressure of tumors by dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights.

Hompland T, Gulliksrud K, Ellingsen C, Rofstad EK.

Acta Oncol. 2013 Apr;52(3):627-35. doi: 10.3109/0284186X.2012.737931. Epub 2012 Nov 6.

PMID:
23126523
39.

Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI.

Hompland T, Ellingsen C, Øvrebø KM, Rofstad EK.

Cancer Res. 2012 Oct 1;72(19):4899-908. doi: 10.1158/0008-5472.CAN-12-0903.

40.

Vascular abnormalities associated with acute hypoxia in human melanoma xenografts.

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK.

Radiother Oncol. 2012 Oct;105(1):72-8. doi: 10.1016/j.radonc.2012.08.018. Epub 2012 Sep 27.

PMID:
23022175
41.

Sunitinib treatment does not improve blood supply but induces hypoxia in human melanoma xenografts.

Gaustad JV, Simonsen TG, Leinaas MN, Rofstad EK.

BMC Cancer. 2012 Sep 4;12:388. doi: 10.1186/1471-2407-12-388.

42.

High interstitial fluid pressure is associated with tumor-line specific vascular abnormalities in human melanoma xenografts.

Simonsen TG, Gaustad JV, Leinaas MN, Rofstad EK.

PLoS One. 2012;7(6):e40006. doi: 10.1371/journal.pone.0040006. Epub 2012 Jun 29.

43.

Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of tumors: a preclinical study of cervical carcinoma and melanoma xenografts.

Øvrebø KM, Ellingsen C, Hompland T, Rofstad EK.

Acta Oncol. 2013 Apr;52(3):604-11. doi: 10.3109/0284186X.2012.689851. Epub 2012 Jun 7.

PMID:
22671573
44.

Dynamic contrast-enhanced magnetic resonance imaging of the metastatic potential of melanoma xenografts.

Ovrebø KM, Ellingsen C, Galappathi K, Rofstad EK.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):e121-7. doi: 10.1016/j.ijrobp.2011.12.019. Epub 2012 Feb 28.

PMID:
22381901
45.

A novel application of dorsal window chambers: repetitive imaging of tumor-associated lymphatics.

Gaustad JV, Simonsen TG, Leinaas MN, Rofstad EK.

Microvasc Res. 2012 May;83(3):360-5. doi: 10.1016/j.mvr.2012.02.003. Epub 2012 Feb 9.

PMID:
22342351
46.

Microenvironment-associated lymph node metastasis of human cervical carcinoma xenografts.

Ellingsen C, Hompland T, Mathiesen B, Rofstad EK.

Acta Oncol. 2012 Apr;51(4):465-72. doi: 10.3109/0284186X.2011.636751. Epub 2012 Jan 31.

PMID:
22292610
47.

pO₂ fluctuation pattern and cycling hypoxia in human cervical carcinoma and melanoma xenografts.

Ellingsen C, Ovrebø KM, Galappathi K, Mathiesen B, Rofstad EK.

Int J Radiat Oncol Biol Phys. 2012 Jul 15;83(4):1317-23. doi: 10.1016/j.ijrobp.2011.09.037. Epub 2012 Jan 21.

PMID:
22270159
48.

Assessment of hypoxia and radiation response in intramuscular experimental tumors by dynamic contrast-enhanced magnetic resonance imaging.

Øvrebø KM, Hompland T, Mathiesen B, Rofstad EK.

Radiother Oncol. 2012 Mar;102(3):429-35. doi: 10.1016/j.radonc.2011.11.013. Epub 2011 Dec 24.

PMID:
22197352
49.

Assessment of tumor hypoxia and interstitial fluid pressure by gadomelitol-based dynamic contrast-enhanced magnetic resonance imaging.

Gulliksrud K, Hompland T, Galappathi K, Rofstad EK.

Radiother Oncol. 2011 Oct;101(1):217-22. doi: 10.1016/j.radonc.2011.06.036. Epub 2011 Aug 15.

PMID:
21840612
50.

Assessment of tumor radioresponsiveness and metastatic potential by dynamic contrast-enhanced magnetic resonance imaging.

Øvrebø KM, Gulliksrud K, Mathiesen B, Rofstad EK.

Int J Radiat Oncol Biol Phys. 2011 Sep 1;81(1):255-61. doi: 10.1016/j.ijrobp.2011.04.008.

PMID:
21816291

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