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Cardiopulmonary Resuscitation in Adults Over 80: Outcome and the Perception of Appropriateness by Clinicians.

Druwé P, Benoit DD, Monsieurs KG, Gagg J, Nakahara S, Alpert EA, van Schuppen H, Élő G, Huybrechts SA, Mpotos N, Joly LM, Xanthos T, Roessler M, Paal P, Cocchi MN, Bjørshol C, Nurmi J, Salmeron PP, Owczuk R, Svavarsdóttir H, Cimpoesu D, Raffay V, Pachys G, De Paepe P, Piers R; REAPPROPRIATE study group.

J Am Geriatr Soc. 2020 Jan;68(1):39-45. doi: 10.1111/jgs.16270. Epub 2019 Dec 15.


Ranking hospitals when performance and risk factors are correlated: A simulation-based comparison of risk adjustment approaches for binary outcomes.

Roessler M, Schmitt J, Schoffer O.

PLoS One. 2019 Dec 4;14(12):e0225844. doi: 10.1371/journal.pone.0225844. eCollection 2019.


Manipulating the Optical Properties of Carbon Dots by Fine-Tuning their Structural Features.

Luo H, Papaioannou N, Salvadori E, Roessler MM, Ploenes G, van Eck ERH, Tanase LC, Feng J, Sun Y, Yang Y, Danaie M, Belen Jorge A, Sapelkin A, Durrant J, Dimitrov SD, Titirici MM.

ChemSusChem. 2019 Oct 8;12(19):4432-4441. doi: 10.1002/cssc.201901795. Epub 2019 Sep 10.


Protein film electrochemical EPR spectroscopy as a technique to investigate redox reactions in biomolecules.

Abdiaziz K, Salvadori E, Sokol KP, Reisner E, Roessler MM.

Chem Commun (Camb). 2019 Jul 23;55(60):8840-8843. doi: 10.1039/c9cc03212f.


Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division.

Greaves RF, Bernardini S, Ferrari M, Fortina P, Gouget B, Gruson D, Lang T, Loh TP, Morris HA, Park JY, Roessler M, Yin P, Kricka LJ.

Clin Chim Acta. 2019 Aug;495:570-589. doi: 10.1016/j.cca.2019.05.021. Epub 2019 May 28.


Defining optimal electron transfer partners for light-driven cytochrome P450 reactions.

Mellor SB, Vinde MH, Nielsen AZ, Hanke GT, Abdiaziz K, Roessler MM, Burow M, Motawia MS, Møller BL, Jensen PE.

Metab Eng. 2019 Sep;55:33-43. doi: 10.1016/j.ymben.2019.05.003. Epub 2019 May 12.


Rotaxane-Based Transition Metal Complexes: Effect of the Mechanical Bond on Structure and Electronic Properties.

Cirulli M, Kaur A, Lewis JEM, Zhang Z, Kitchen JA, Goldup SM, Roessler MM.

J Am Chem Soc. 2019 Jan 16;141(2):879-889. doi: 10.1021/jacs.8b09715. Epub 2019 Jan 2.


Perception of inappropriate cardiopulmonary resuscitation by clinicians working in emergency departments and ambulance services: The REAPPROPRIATE international, multi-centre, cross sectional survey.

Druwé P, Monsieurs KG, Piers R, Gagg J, Nakahara S, Alpert EA, van Schuppen H, Élő G, Truhlář A, Huybrechts SA, Mpotos N, Joly LM, Xanthos T, Roessler M, Paal P, Cocchi MN, BjØrshol C, Pauliková M, Nurmi J, Salmeron PP, Owczuk R, Svavarsdóttir H, Deasy C, Cimpoesu D, Ioannides M, Fuenzalida PA, Kurland L, Raffay V, Pachys G, Gadeyne B, Steen J, Vansteelandt S, De Paepe P, Benoit DD.

Resuscitation. 2018 Nov;132:112-119. doi: 10.1016/j.resuscitation.2018.09.006. Epub 2018 Sep 12.


The 10 fundamental principles of lay resuscitation: Recommendations by the German Resuscitation Council.

Böttiger BW, Dirks B, Jost U, Kreimeier U, Osche S, Roessler M, Scholz KH, Wingen S.

Eur J Anaesthesiol. 2018 Oct;35(10):721-723. doi: 10.1097/EJA.0000000000000865. No abstract available.


Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control.

Martínez-Lumbreras S, Krysztofinska EM, Thapaliya A, Spilotros A, Matak-Vinkovic D, Salvadori E, Roboti P, Nyathi Y, Muench JH, Roessler MM, Svergun DI, High S, Isaacson RL.

BMC Biol. 2018 Jul 11;16(1):76. doi: 10.1186/s12915-018-0542-3.


Prehospital ultrasound-guided nerve blocks improve reduction-feasibility of dislocated extremity injuries compared to systemic analgesia. A randomized controlled trial.

Büttner B, Mansur A, Kalmbach M, Hinz J, Volk T, Szalai K, Roessler M, Bergmann I.

PLoS One. 2018 Jul 2;13(7):e0199776. doi: 10.1371/journal.pone.0199776. eCollection 2018.


X-ray structural, functional and computational studies of the O2-sensitive E. coli hydrogenase-1 C19G variant reveal an unusual [4Fe-4S] cluster.

Volbeda A, Mouesca JM, Darnault C, Roessler MM, Parkin A, Armstrong FA, Fontecilla-Camps JC.

Chem Commun (Camb). 2018 Jun 26;54(52):7175-7178. doi: 10.1039/c8cc02896f.


[Palliative medicine in emergency medical services].

Roessler M, Eulitz N.

Anaesthesist. 2018 May;67(5):366-374. doi: 10.1007/s00101-018-0429-2. Review. German.


Principles and applications of EPR spectroscopy in the chemical sciences.

Roessler MM, Salvadori E.

Chem Soc Rev. 2018 Apr 23;47(8):2534-2553. doi: 10.1039/c6cs00565a.


A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma.

Liu X, Swen JJ, Diekstra MHM, Boven E, Castellano D, Gelderblom H, Mathijssen RHJ, Vermeulen SH, Oosterwijk E, Junker K, Roessler M, Alexiusdottir K, Sverrisdottir A, Radu MT, Ambert V, Eisen T, Warren A, Rodríguez-Antona C, García-Donas J, Böhringer S, Koudijs KKM, Kiemeney LALM, Rini BI, Guchelaar HJ.

Clin Cancer Res. 2018 May 15;24(10):2350-2356. doi: 10.1158/1078-0432.CCR-17-2815. Epub 2018 Feb 28.


Pre-hospital transthoracic echocardiography for early identification of non-ST-elevation myocardial infarction in patients with acute coronary syndrome.

Bergmann I, Büttner B, Teut E, Jacobshagen C, Hinz J, Quintel M, Mansur A, Roessler M.

Crit Care. 2018 Feb 7;22(1):29. doi: 10.1186/s13054-017-1929-1.


UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.

Hellerschmied D, Roessler M, Lehner A, Gazda L, Stejskal K, Imre R, Mechtler K, Dammermann A, Clausen T.

Nat Commun. 2018 Feb 2;9(1):484. doi: 10.1038/s41467-018-02924-7.


[Optimized resource mobilization and quality of treatment of severely injured patients through a structured trauma room alarm system].

Spering C, Roessler M, Kurlemann T, Dresing K, Stürmer KM, Lehmann W, Sehmisch S.

Unfallchirurg. 2018 Nov;121(11):893-900. doi: 10.1007/s00113-017-0447-6. German.


Ectonucleotidase CD39 expression in regional metastases in head and neck cancer.

Mandapathil M, Boduc M, Roessler M, Güldner C, Walliczek-Dworschak U, Mandic R.

Acta Otolaryngol. 2018 Apr;138(4):428-432. doi: 10.1080/00016489.2017.1405278. Epub 2017 Nov 26.


Using Hyperfine Electron Paramagnetic Resonance Spectroscopy to Define the Proton-Coupled Electron Transfer Reaction at Fe-S Cluster N2 in Respiratory Complex I.

Le Breton N, Wright JJ, Jones AJY, Salvadori E, Bridges HR, Hirst J, Roessler MM.

J Am Chem Soc. 2017 Nov 15;139(45):16319-16326. doi: 10.1021/jacs.7b09261. Epub 2017 Nov 3.


ADAM8 expression in breast cancer derived brain metastases: Functional implications on MMP-9 expression and transendothelial migration in breast cancer cells.

Conrad C, Götte M, Schlomann U, Roessler M, Pagenstecher A, Anderson P, Preston J, Pruessmeyer J, Ludwig A, Li R, Kamm RD, Ritz R, Carl B, Nimsky C, Bartsch JW.

Int J Cancer. 2018 Feb 15;142(4):779-791. doi: 10.1002/ijc.31090. Epub 2017 Oct 31.


CD73 expression in lymph node metastases in patients with head and neck cancer.

Mandapathil M, Boduc M, Netzer C, Güldner C, Roessler M, Wallicek-Dworschak U, Jahns E, Stuck B.

Acta Otolaryngol. 2018 Feb;138(2):180-184. doi: 10.1080/00016489.2017.1378436. Epub 2017 Sep 22.


Foxp3 expression in lymph node metastases in patients with head and neck cancer.

Boduc M, Roessler M, Mandic R, Netzer C, Güldner C, Walliczek-Dworschak U, Stuck BA, Mandapathil M.

Acta Otolaryngol. 2017 Nov;137(11):1215-1219. doi: 10.1080/00016489.2017.1353705. Epub 2017 Jul 25.


Retuning the Catalytic Bias and Overpotential of a [NiFe]-Hydrogenase via a Single Amino Acid Exchange at the Electron Entry/Exit Site.

Adamson H, Robinson M, Wright JJ, Flanagan LA, Walton J, Elton D, Gavaghan DJ, Bond AM, Roessler MM, Parkin A.

J Am Chem Soc. 2017 Aug 9;139(31):10677-10686. doi: 10.1021/jacs.7b03611. Epub 2017 Jul 26.


Population Modeling Integrating Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, and Clinical Outcome in Patients With Sunitinib-Treated Cancer.

Diekstra MH, Fritsch A, Kanefendt F, Swen JJ, Moes D, Sörgel F, Kinzig M, Stelzer C, Schindele D, Gauler T, Hauser S, Houtsma D, Roessler M, Moritz B, Mross K, Bergmann L, Oosterwijk E, Kiemeney LA, Guchelaar HJ, Jaehde U.

CPT Pharmacometrics Syst Pharmacol. 2017 Sep;6(9):604-613. doi: 10.1002/psp4.12210. Epub 2017 Jul 13.


Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans.

Serwas D, Su TY, Roessler M, Wang S, Dammermann A.

J Cell Biol. 2017 Jun 5;216(6):1659-1671. doi: 10.1083/jcb.201610070. Epub 2017 Apr 14.


Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

van der Zanden LFM, Vermeulen SH, Oskarsdottir A, Maurits JSF, Diekstra MHM, Ambert V, Cambon-Thomsen A, Castellano D, Fritsch A, Garcia Donas J, Guarch Troyas R, Guchelaar HJ, Hartmann A, Hulsbergen-van de Kaa C, Jaehde U, Junker K, Martinez-Cardus A, Masson G, Oosterwijk-Wakka J, Radu MT, Rafnar T, Rodriguez-Antona C, Roessler M, Ruijtenbeek R, Stefansson K, Warren A, Wessels L, Eisen T, Kiemeney LALM, Oosterwijk E.

Urol Oncol. 2017 Aug;35(8):529.e9-529.e16. doi: 10.1016/j.urolonc.2017.03.009. Epub 2017 Apr 3.


Recommended practice for out-of-hospital emergency anaesthesia in adults: Statement from the Out-of-Hospital Emergency Anaesthesia Working Group of the Emergency Medicine Research Group of the German Society of Anaesthesiology and Intensive Care.

Hossfeld B, Bein B, Boettiger BW, Bohn A, Fischer M, Graesner JT, Hinkelbein J, Kill C, Lott C, Popp E, Roessler M, Schaumberg A, Wenzel V, Bernhard M.

Eur J Anaesthesiol. 2016 Dec;33(12):881-897. No abstract available.


The pre-hospital administration of tranexamic acid to patients with multiple injuries and its effects on rotational thrombelastometry: a prospective observational study in pre-hospital emergency medicine.

Kunze-Szikszay N, Krack LA, Wildenauer P, Wand S, Heyne T, Walliser K, Spering C, Bauer M, Quintel M, Roessler M.

Scand J Trauma Resusc Emerg Med. 2016 Oct 10;24(1):122.


Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC).

Joerger M, von Pawel J, Kraff S, Fischer JR, Eberhardt W, Gauler TC, Mueller L, Reinmuth N, Reck M, Kimmich M, Mayer F, Kopp HG, Behringer DM, Ko YD, Hilger RA, Roessler M, Kloft C, Henrich A, Moritz B, Miller MC, Salamone SJ, Jaehde U.

Ann Oncol. 2016 Oct;27(10):1895-902. doi: 10.1093/annonc/mdw290. Epub 2016 Aug 8.


Prospective, Multicenter Study of 5-Fluorouracil Therapeutic Drug Monitoring in Metastatic Colorectal Cancer Treated in Routine Clinical Practice.

Wilhelm M, Mueller L, Miller MC, Link K, Holdenrieder S, Bertsch T, Kunzmann V, Stoetzer OJ, Suttmann I, Braess J, Birkmann J, Roessler M, Moritz B, Kraff S, Salamone SJ, Jaehde U.

Clin Colorectal Cancer. 2016 Dec;15(4):381-388. doi: 10.1016/j.clcc.2016.04.001. Epub 2016 May 7.


Small-volume potentiometric titrations: EPR investigations of Fe-S cluster N2 in mitochondrial complex I.

Wright JJ, Salvadori E, Bridges HR, Hirst J, Roessler MM.

J Inorg Biochem. 2016 Sep;162:201-206. doi: 10.1016/j.jinorgbio.2016.04.025. Epub 2016 Apr 20.


Guiding Principles of Hydrogenase Catalysis Instigated and Clarified by Protein Film Electrochemistry.

Armstrong FA, Evans RM, Hexter SV, Murphy BJ, Roessler MM, Wulff P.

Acc Chem Res. 2016 May 17;49(5):884-92. doi: 10.1021/acs.accounts.6b00027. Epub 2016 Apr 22. Review.


Re-engineering a NiFe hydrogenase to increase the H2 production bias while maintaining native levels of O2 tolerance.

Flanagan LA, Wright JJ, Roessler MM, Moir JW, Parkin A.

Chem Commun (Camb). 2016 Jul 12;52(58):9133-6. doi: 10.1039/c6cc00515b.


Use of the GlideScope®-Ranger for pre-hospital intubations by anaesthesia trained emergency physicians - an observational study.

Russo SG, Nickel EA, Leissner KB, Schwerdtfeger K, Bauer M, Roessler MS.

BMC Emerg Med. 2016 Jan 29;16:8. doi: 10.1186/s12873-016-0069-2.


Energy conversion, redox catalysis and generation of reactive oxygen species by respiratory complex I.

Hirst J, Roessler MM.

Biochim Biophys Acta. 2016 Jul;1857(7):872-83. doi: 10.1016/j.bbabio.2015.12.009. Epub 2015 Dec 22. Review.


Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.

Meulendijks D, Lassen UN, Siu LL, Huitema AD, Karanikas V, Mau-Sorensen M, Jonker DJ, Hansen AR, Simcox ME, Schostack KJ, Bottino D, Zhong H, Roessler M, Vega-Harring SM, Jarutat T, Geho D, Wang K, DeMario M, Goss GD, Schellens JH.

Clin Cancer Res. 2016 Feb 15;22(4):858-67. doi: 10.1158/1078-0432.CCR-15-1506. Epub 2015 Oct 7.


Blood-sampling collection prior to surgery may have a significant influence upon biomarker concentrations measured.

Kahn N, Riedlinger J, Roeßler M, Rabe C, Lindner M, Koch I, Schott-Hildebrand S, Herth FJ, Schneider MA, Meister M, Muley TR.

Clin Proteomics. 2015 Jul 31;12(1):19. doi: 10.1186/s12014-015-9093-6. eCollection 2015.


Failure of a Knee Joint Load Absorber: Pain, Metallosis and Soft Tissue Damage.

Schüttler KF, Roessler M, Fuchs-Winkelmann S, Efe T, Heyse TJ.

HSS J. 2015 Jul;11(2):172-6. doi: 10.1007/s11420-015-9436-x. Epub 2015 Apr 2. No abstract available.


Discovery of Dark pH-Dependent H(+) Migration in a [NiFe]-Hydrogenase and Its Mechanistic Relevance: Mobilizing the Hydrido Ligand of the Ni-C Intermediate.

Murphy BJ, Hidalgo R, Roessler MM, Evans RM, Ash PA, Myers WK, Vincent KA, Armstrong FA.

J Am Chem Soc. 2015 Jul 8;137(26):8484-9. doi: 10.1021/jacs.5b03182. Epub 2015 Jun 23.


[Erratum to: Implementation of a new emergency room protocol at a University Medical Center in Germany : Basis for improved flow of information, adequate quality management and scientific assessment].

Ross D, Hinz J, Mansur A, Mielck F, Roessler M, Quintel M, Bauer M.

Anaesthesist. 2015 May;64(5):389. doi: 10.1007/s00101-015-0038-2. German. No abstract available.


[Implementation of a new emergency room protocol at a University Medical Center in Germany: basis for improved flow of information, adequate quality management and scientific assessment].

Ross D, Hinz J, Mansur A, Mielck F, Roessler M, Quintel M, Bauer M.

Anaesthesist. 2015 Mar;64(3):208-17. doi: 10.1007/s00101-015-0011-0. German. Erratum in: Anaesthesist. 2015 May;64(5):389.


A phase I monotherapy study of RG7212, a first-in-class monoclonal antibody targeting TWEAK signaling in patients with advanced cancers.

Lassen UN, Meulendijks D, Siu LL, Karanikas V, Mau-Sorensen M, Schellens JH, Jonker DJ, Hansen AR, Simcox ME, Schostack KJ, Bottino D, Zhong H, Roessler M, Vega-Harring SM, Jarutat T, Geho D, Wang K, DeMario M, Goss GD.

Clin Cancer Res. 2015 Jan 15;21(2):258-66. doi: 10.1158/1078-0432.CCR-14-1334. Epub 2014 Nov 11.


Prehospital noninvasive ventilation for acute respiratory failure: systematic review, network meta-analysis, and individual patient data meta-analysis.

Goodacre S, Stevens JW, Pandor A, Poku E, Ren S, Cantrell A, Bounes V, Mas A, Payen D, Petrie D, Roessler MS, Weitz G, Ducros L, Plaisance P.

Acad Emerg Med. 2014 Sep;21(9):960-70. doi: 10.1111/acem.12466. Review.


[Fluid resuscitation in hemorrhage].

Roessler M, Bode K, Bauer M.

Anaesthesist. 2014 Oct;63(10):730-44. doi: 10.1007/s00101-014-2377-9. Review. German.


A prospective, blinded evaluation of a video-assisted '4-stage approach' during undergraduate student practical skills training.

Schwerdtfeger K, Wand S, Schmid O, Roessler M, Quintel M, Leissner KB, Russo SG.

BMC Med Educ. 2014 May 22;14:104. doi: 10.1186/1472-6920-14-104.


Salvage surgery for head and neck squamous cell carcinoma.

Mandapathil M, Roessler M, Werner JA, Silver CE, Rinaldo A, Ferlito A.

Eur Arch Otorhinolaryngol. 2014 Jul;271(7):1845-50. doi: 10.1007/s00405-014-3043-1. Epub 2014 Apr 23. No abstract available.


The effect of changing the sequence of cuff inflation and device fixation with the LMA-Supreme® on device position, ventilatory complications, and airway morbidity: a clinical and fiberscopic study.

Bergmann I, Crozier TA, Roessler M, Schotola H, Mansur A, Büttner B, Hinz JM, Bauer M.

BMC Anesthesiol. 2014 Jan 4;14:2. doi: 10.1186/1471-2253-14-2.


The chorioallantoic membrane assay is a promising ex vivo model system for the study of vascular anomalies.

Jedelská J, Strehlow B, Bakowsky U, Aigner A, Höbel S, Bette M, Roessler M, Franke N, Teymoortash A, Werner JA, Eivazi B, Mandic R.

In Vivo. 2013 Nov-Dec;27(6):701-5.


Freehand SPECT for sentinel lymph node detection in patients with head and neck cancer: first experiences.

Mandapathil M, Teymoortash A, Heinis J, Wiegand S, Güldner C, Hoch S, Roeßler M, Werner JA.

Acta Otolaryngol. 2014 Jan;134(1):100-4. doi: 10.3109/00016489.2013.832376. Epub 2013 Nov 21.


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