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Haemodiafiltration does not lower protein-bound uraemic toxin levels compared with haemodialysis in a paediatric population.

Snauwaert E, Van Biesen W, Raes A, Glorieux G, Vande Walle J, Roels S, Vanholder R, Askiti V, Azukaitis K, Bayazit A, Canpolat N, Fischbach M, Saoussen K, Litwin M, Obrycki L, Paglialonga F, Ranchin B, Samaille C, Schaefer F, Schmitt CP, Spasojevic B, Stefanidis CJ, Shroff R, Eloot S.

Nephrol Dial Transplant. 2019 Jul 30. pii: gfz132. doi: 10.1093/ndt/gfz132. [Epub ahead of print]


Short communication: Mycolicibacterium smegmatis, basonym Mycobacterium smegmatis, causing pyogranulomatous mastitis and its cross-reactivity in bovine (para)tuberculosis testing.

Supré K, Roupie V, Ribbens S, Stevens M, Boyen F, Roels S.

J Dairy Sci. 2019 Sep;102(9):8405-8409. doi: 10.3168/jds.2019-16610. Epub 2019 Jul 10.


Uremic Toxin Concentrations are Related to Residual Kidney Function in the Pediatric Hemodialysis Population.

Snauwaert E, Holvoet E, Van Biesen W, Raes A, Glorieux G, Vande Walle J, Roels S, Vanholder R, Askiti V, Azukaitis K, Bayazit A, Canpolat N, Fischbach M, Godefroid N, Krid S, Litwin M, Obrycki L, Paglialonga F, Ranchin B, Samaille C, Schaefer F, Schmitt CP, Spasojevic B, Stefanidis CJ, Van Dyck M, Van Hoeck K, Collard L, Eloot S, Shroff R.

Toxins (Basel). 2019 Apr 24;11(4). pii: E235. doi: 10.3390/toxins11040235.


Short-term biodistribution and clearance of intravenously administered silica nanoparticles.

Waegeneers N, Brasseur A, Van Doren E, Van der Heyden S, Serreyn PJ, Pussemier L, Mast J, Schneider YJ, Ruttens A, Roels S.

Toxicol Rep. 2018 May 23;5:632-638. doi: 10.1016/j.toxrep.2018.05.004. eCollection 2018.


Combined Analysis of GAD65, miR-375, and Unmethylated Insulin DNA Following Islet Transplantation in Patients With T1D.

Roels S, Costa OR, Tersey SA, Stangé G, De Smet D, Balti EV, Gillard P, Keymeulen B, Ling Z, Pipeleers DG, Gorus FK, Mirmira RG, Martens GA.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):451-460. doi: 10.1210/jc.2017-02520.


Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

Clark TA, Chung JH, Kennedy M, Hughes JD, Chennagiri N, Lieber DS, Fendler B, Young L, Zhao M, Coyne M, Breese V, Young G, Donahue A, Pavlick D, Tsiros A, Brennan T, Zhong S, Mughal T, Bailey M, He J, Roels S, Frampton GM, Spoerke JM, Gendreau S, Lackner M, Schleifman E, Peters E, Ross JS, Ali SM, Miller VA, Gregg JP, Stephens PJ, Welsh A, Otto GA, Lipson D.

J Mol Diagn. 2018 Sep;20(5):686-702. doi: 10.1016/j.jmoldx.2018.05.004. Epub 2018 Jun 22.


Evaluation of mycobacteria-specific gamma interferon and antibody responses before and after a single intradermal skin test in cattle naturally exposed to M. avium subsp. paratuberculosis and experimentally infected with M. bovis.

Roupie V, Alonso-Velasco E, Van Der Heyden S, Holbert S, Duytschaever L, Berthon P, Van Dosselaer I, Van Campe W, Mostin L, Biet F, Roels S, Huygen K, Fretin D.

Vet Immunol Immunopathol. 2018 Feb;196:35-47. doi: 10.1016/j.vetimm.2017.12.007. Epub 2017 Dec 12.


An analytical comparison of three immunoassay platforms for subpicomolar detection of protein biomarker GAD65.

Costa OR, Verhaeghen K, Roels S, Stangé G, Ling Z, Pipeleers D, Gorus FK, Martens GA.

PLoS One. 2018 Mar 8;13(3):e0193670. doi: 10.1371/journal.pone.0193670. eCollection 2018.


Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds.

Song I, Roels S, Martens GA, Bouwens L.

PLoS One. 2017 Oct 17;12(10):e0186480. doi: 10.1371/journal.pone.0186480. eCollection 2017.


Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients.

Eloot S, Van Biesen W, Roels S, Delrue W, Schepers E, Dhondt A, Vanholder R, Glorieux G.

PLoS One. 2017 Oct 10;12(10):e0186010. doi: 10.1371/journal.pone.0186010. eCollection 2017.


Concentrations of representative uraemic toxins in a healthy versus non-dialysis chronic kidney disease paediatric population.

Snauwaert E, Van Biesen W, Raes A, Glorieux G, Van Bogaert V, Van Hoeck K, Coppens M, Roels S, Vande Walle J, Eloot S.

Nephrol Dial Transplant. 2018 Jun 1;33(6):978-986. doi: 10.1093/ndt/gfx224.


Accumulation of uraemic toxins is reflected only partially by estimated GFR in paediatric patients with chronic kidney disease.

Snauwaert E, Van Biesen W, Raes A, Holvoet E, Glorieux G, Van Hoeck K, Van Dyck M, Godefroid N, Vanholder R, Roels S, Walle JV, Eloot S.

Pediatr Nephrol. 2018 Feb;33(2):315-323. doi: 10.1007/s00467-017-3802-5. Epub 2017 Sep 22.


Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden.

Chalmers ZR, Connelly CF, Fabrizio D, Gay L, Ali SM, Ennis R, Schrock A, Campbell B, Shlien A, Chmielecki J, Huang F, He Y, Sun J, Tabori U, Kennedy M, Lieber DS, Roels S, White J, Otto GA, Ross JS, Garraway L, Miller VA, Stephens PJ, Frampton GM.

Genome Med. 2017 Apr 19;9(1):34. doi: 10.1186/s13073-017-0424-2.


Susceptibility of Pigs to Zoonotic Hepatitis E Virus Genotype 3 Isolated from a Wild Boar.

Thiry D, Rose N, Mauroy A, Paboeuf F, Dams L, Roels S, Pavio N, Thiry E.

Transbound Emerg Dis. 2017 Oct;64(5):1589-1597. doi: 10.1111/tbed.12550. Epub 2016 Jul 31.


Do refined consensus guidelines improve the uniformity of clinical target volume delineation for rectal cancer? Results of a national review project.

Joye I, Macq G, Vaes E, Roels S, Lambrecht M, Pelgrims A, Bussels B, Vancleef A, Stellamans K, Scalliet P, Weytjens R, Christian N, Boulanger AS, Donnay L, Van Brussel S, Moretti L, Van den Bergh L, Van Eycken E, Debucquoy A, Haustermans K.

Radiother Oncol. 2016 Aug;120(2):202-6. doi: 10.1016/j.radonc.2016.06.005. Epub 2016 Jun 30.


Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias.

Wang K, Sanchez-Martin M, Wang X, Knapp KM, Koche R, Vu L, Nahas MK, He J, Hadler M, Stein EM, Tallman MS, Donahue AL, Frampton GM, Lipson D, Roels S, Stephens PJ, Sanford EM, Brennan T, Otto GA, Yelensky R, Miller VA, Kharas MG, Levine RL, Ferrando A, Armstrong SA, Krivtsov AV.

Leukemia. 2017 Jan;31(1):151-158. doi: 10.1038/leu.2016.166. Epub 2016 Jun 13.


STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage.

De Groef S, Renmans D, Cai Y, Leuckx G, Roels S, Staels W, Gradwohl G, Baeyens L, Heremans Y, Martens GA, De Leu N, Sojoodi M, Van de Casteele M, Heimberg H.

Cell Death Dis. 2016 Jun 23;7(6):e2272. doi: 10.1038/cddis.2016.171.


First TBEV serological screening in Flemish wild boar.

Roelandt S, Suin V, Van der Stede Y, Lamoral S, Marche S, Tignon M, Saiz JC, Escribano-Romero E, Casaer J, Brochier B, Van Gucht S, Roels S, Vervaeke M.

Infect Ecol Epidemiol. 2016 Apr 15;6:31099. doi: 10.3402/iee.v6.31099. eCollection 2016.


Desmopressin (melt) therapy in children with monosymptomatic nocturnal enuresis and nocturnal polyuria results in improved neuropsychological functioning and sleep.

Van Herzeele C, Dhondt K, Roels SP, Raes A, Hoebeke P, Groen LA, Vande Walle J.

Pediatr Nephrol. 2016 Sep;31(9):1477-84. doi: 10.1007/s00467-016-3351-3. Epub 2016 Apr 11.


Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting.

He J, Abdel-Wahab O, Nahas MK, Wang K, Rampal RK, Intlekofer AM, Patel J, Krivstov A, Frampton GM, Young LE, Zhong S, Bailey M, White JR, Roels S, Deffenbaugh J, Fichtenholtz A, Brennan T, Rosenzweig M, Pelak K, Knapp KM, Brennan KW, Donahue AL, Young G, Garcia L, Beckstrom ST, Zhao M, White E, Banning V, Buell J, Iwanik K, Ross JS, Morosini D, Younes A, Hanash AM, Paietta E, Roberts K, Mullighan C, Dogan A, Armstrong SA, Mughal T, Vergilio JA, Labrecque E, Erlich R, Vietz C, Yelensky R, Stephens PJ, Miller VA, van den Brink MR, Otto GA, Lipson D, Levine RL.

Blood. 2016 Jun 16;127(24):3004-14. doi: 10.1182/blood-2015-08-664649. Epub 2016 Mar 10.


Evaluation of Second-Level Inference in fMRI Analysis.

Roels SP, Loeys T, Moerkerke B.

Comput Intell Neurosci. 2016;2016:1068434. doi: 10.1155/2016/1068434. Epub 2015 Dec 27.


Microbial diversity and metabolite composition of Belgian red-brown acidic ales.

Snauwaert I, Roels SP, Van Nieuwerburg F, Van Landschoot A, De Vuyst L, Vandamme P.

Int J Food Microbiol. 2016 Mar 16;221:1-11. doi: 10.1016/j.ijfoodmicro.2015.12.009. Epub 2016 Jan 6.


Serologic screening for 13 infectious agents in roe deer (Capreolus capreolus) in Flanders.

Tavernier P, Sys SU, De Clercq K, De Leeuw I, Caij AB, De Baere M, De Regge N, Fretin D, Roupie V, Govaerts M, Heyman P, Vanrompay D, Yin L, Kalmar I, Suin V, Brochier B, Dobly A, De Craeye S, Roelandt S, Goossens E, Roels S.

Infect Ecol Epidemiol. 2015 Nov 24;5:29862. doi: 10.3402/iee.v5.29862. eCollection 2015.


The distribution of BRAF gene fusions in solid tumors and response to targeted therapy.

Ross JS, Wang K, Chmielecki J, Gay L, Johnson A, Chudnovsky J, Yelensky R, Lipson D, Ali SM, Elvin JA, Vergilio JA, Roels S, Miller VA, Nakamura BN, Gray A, Wong MK, Stephens PJ.

Int J Cancer. 2016 Feb 15;138(4):881-90. doi: 10.1002/ijc.29825. Epub 2015 Sep 8.


Neuropsychological functioning related to specific characteristics of nocturnal enuresis.

Van Herzeele C, Dhondt K, Roels SP, Raes A, Groen LA, Hoebeke P, Walle JV.

J Pediatr Urol. 2015 Aug;11(4):208.e1-6. doi: 10.1016/j.jpurol.2015.04.033. Epub 2015 Jun 27.


Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.

Frampton GM, Ali SM, Rosenzweig M, Chmielecki J, Lu X, Bauer TM, Akimov M, Bufill JA, Lee C, Jentz D, Hoover R, Ou SH, Salgia R, Brennan T, Chalmers ZR, Jaeger S, Huang A, Elvin JA, Erlich R, Fichtenholtz A, Gowen KA, Greenbowe J, Johnson A, Khaira D, McMahon C, Sanford EM, Roels S, White J, Greshock J, Schlegel R, Lipson D, Yelensky R, Morosini D, Ross JS, Collisson E, Peters M, Stephens PJ, Miller VA.

Cancer Discov. 2015 Aug;5(8):850-9. doi: 10.1158/2159-8290.CD-15-0285. Epub 2015 May 13.


Bootstrapping fMRI Data: Dealing with Misspecification.

Roels SP, Moerkerke B, Loeys T.

Neuroinformatics. 2015 Jul;13(3):337-52. doi: 10.1007/s12021-015-9261-x.


Sleep fragmentation and periodic limb movements in children with monosymptomatic nocturnal enuresis and polyuria.

Dhondt K, Van Herzeele C, Roels SP, Raes A, Groen LA, Hoebeke P, Walle JV.

Pediatr Nephrol. 2015 Jul;30(7):1157-62. doi: 10.1007/s00467-015-3044-3. Epub 2015 Feb 11.


Periodic limb movements during sleep are associated with a lower quality of life in children with monosymptomatic nocturnal enuresis.

Van Herzeele C, Dhondt K, Roels SP, Raes A, Groen LA, Hoebeke P, Vande Walle J.

Eur J Pediatr. 2015 Jul;174(7):897-902. doi: 10.1007/s00431-014-2474-4. Epub 2015 Jan 9.


Data-analytical stability of cluster-wise and peak-wise inference in fMRI data analysis.

Roels SP, Bossier H, Loeys T, Moerkerke B.

J Neurosci Methods. 2015 Jan 30;240:37-47. doi: 10.1016/j.jneumeth.2014.10.024. Epub 2014 Nov 6.


Autochthonous tick-borne encephalitis virus-seropositive cattle in Belgium: a risk-based targeted serological survey.

Roelandt S, Suin V, Riocreux F, Lamoral S, Van der Heyden S, Van der Stede Y, Lambrecht B, Caij B, Brochier B, Roels S, Van Gucht S.

Vector Borne Zoonotic Dis. 2014 Sep;14(9):640-7. doi: 10.1089/vbz.2014.1576.


Multiple testing in fMRI: an empirical case study on the balance between sensitivity, specificity, and stability.

Durnez J, Roels SP, Moerkerke B.

Biom J. 2014 Jul;56(4):649-61. doi: 10.1002/bimj.201200056. Epub 2014 May 7.


Irrelevant location information influences accuracy in bowling.

Braem S, Supply S, Roels SP, Notebaert W.

Motor Control. 2015 Jan;19(1):25-33. doi: 10.1123/mc.2012-0104. Epub 2014 Apr 9.


Vaccination of mice using the West Nile virus E-protein in a DNA prime-protein boost strategy stimulates cell-mediated immunity and protects mice against a lethal challenge.

De Filette M, Soehle S, Ulbert S, Richner J, Diamond MS, Sinigaglia A, Barzon L, Roels S, Lisziewicz J, Lorincz O, Sanders NN.

PLoS One. 2014 Feb 4;9(2):e87837. doi: 10.1371/journal.pone.0087837. eCollection 2014. Erratum in: PLoS One. 2014;9(2):e91631.


Effect of a DIVA vaccine with and without in-feed use of coated calcium-butyrate on transmission of Salmonella Typhimurium in pigs.

De Ridder L, Maes D, Dewulf J, Pasmans F, Boyen F, Haesebrouck F, Méroc E, Roels S, Leyman B, Butaye P, Van der Stede Y.

BMC Vet Res. 2013 Dec 4;9:243. doi: 10.1186/1746-6148-9-243.


Coupling of drug containing liposomes to microbubbles improves ultrasound triggered drug delivery in mice.

Cool SK, Geers B, Roels S, Stremersch S, Vanderperren K, Saunders JH, De Smedt SC, Demeester J, Sanders NN.

J Control Release. 2013 Dec 28;172(3):885-93. doi: 10.1016/j.jconrel.2013.09.014. Epub 2013 Sep 25.


Laboratory activities involving transmissible spongiform encephalopathy causing agents: risk assessment and biosafety recommendations in Belgium.

Leunda A, Van Vaerenbergh B, Baldo A, Roels S, Herman P.

Prion. 2013 Sep-Oct;7(5):420-33. doi: 10.4161/pri.26533. Epub 2013 Sep 20. Review.


An essential role for γ-herpesvirus latency-associated nuclear antigen homolog in an acute lymphoproliferative disease of cattle.

Palmeira L, Sorel O, Van Campe W, Boudry C, Roels S, Myster F, Reschner A, Coulie PG, Kerkhofs P, Vanderplasschen A, Dewals BG.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):E1933-42. doi: 10.1073/pnas.1216531110. Epub 2013 Apr 29.


Favourable outcome in a patient bitten by a rabid bat infected with the European bat lyssavirus-1.

Van Gucht S, Verlinde R, Colyn J, Vanderpas J, Vanhoof R, Roels S, Francart A, Brochier B, Suin V.

Acta Clin Belg. 2013 Jan-Feb;68(1):54-8.


M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A.

Ibañez LI, Roose K, De Filette M, Schotsaert M, De Sloovere J, Roels S, Pollard C, Schepens B, Grooten J, Fiers W, Saelens X.

PLoS One. 2013;8(3):e59081. doi: 10.1371/journal.pone.0059081. Epub 2013 Mar 18.


Spatiotemporal dynamics of Puumala hantavirus in suburban reservoir rodent populations.

Dobly A, Yzoard C, Cochez C, Ducoffre G, Aerts M, Roels S, Heyman P.

J Vector Ecol. 2012 Dec;37(2):276-83. doi: 10.1111/j.1948-7134.2012.00228.x.


Infectivity of rabies virus-exposed macrophages.

Nazé F, Suin V, Lamoral S, Francart A, Brochier B, Roels S, Mast J, Kalai M, Van Gucht S.

Microbes Infect. 2013 Feb;15(2):115-25. doi: 10.1016/j.micinf.2012.10.018. Epub 2012 Nov 14.


Tick-borne encephalitis virus seropositive dog detected in Belgium: screening of the canine population as sentinels for public health.

Roelandt S, Heyman P, De Filette M, Vene S, Van der Stede Y, Caij AB, Tavernier P, Dobly A, De Bosschere H, Vyt P, Meersschaert C, Roels S.

Vector Borne Zoonotic Dis. 2011 Oct;11(10):1371-6. doi: 10.1089/vbz.2011.0647. Epub 2011 Sep 15.


Rapid evolution caused by pollinator loss in Mimulus guttatus.

Roels SA, Kelly JK.

Evolution. 2011 Sep;65(9):2541-52. doi: 10.1111/j.1558-5646.2011.01326.x.


Value of diffusion-weighted magnetic resonance imaging for prediction and early assessment of response to neoadjuvant radiochemotherapy in rectal cancer: preliminary results.

Lambrecht M, Vandecaveye V, De Keyzer F, Roels S, Penninckx F, Van Cutsem E, Filip C, Haustermans K.

Int J Radiat Oncol Biol Phys. 2012 Feb 1;82(2):863-70. doi: 10.1016/j.ijrobp.2010.12.063. Epub 2011 Mar 11.


Sero-epidemiological study of the presence of hantaviruses in domestic dogs and cats from Belgium.

Dobly A, Cochez C, Goossens E, De Bosschere H, Hansen P, Roels S, Heyman P.

Res Vet Sci. 2012 Apr;92(2):221-4. doi: 10.1016/j.rvsc.2011.02.003. Epub 2011 Mar 8.


Antiserum against the conserved nine amino acid N-terminal peptide of influenza A virus matrix protein 2 is not immunoprotective.

De Filette M, Ysenbaert T, Roose K, Schotsaert M, Roels S, Goossens E, Schepens B, Fiers W, Saelens X.

J Gen Virol. 2011 Feb;92(Pt 2):301-6. doi: 10.1099/vir.0.027086-0. Epub 2010 Oct 21.


Error tolerant indexing and alignment of short reads with covering template families.

Giladi E, Healy J, Myers G, Hart C, Kapranov P, Lipson D, Roels S, Thayer E, Letovsky S.

J Comput Biol. 2010 Oct;17(10):1397-1411. doi: 10.1089/cmb.2010.0005.


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