Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 54

1.

Loss of the Heparan Sulfate Proteoglycan Glypican5 Facilitates Long-Range Sonic Hedgehog Signaling.

Guo W, Roelink H.

Stem Cells. 2019 Jul;37(7):899-909. doi: 10.1002/stem.3018. Epub 2019 May 13.

PMID:
30977233
2.

Gain-of-function Shh mutants activate Smo cell-autonomously independent of Ptch1/2 function.

Casillas C, Roelink H.

Mech Dev. 2018 Oct;153:30-41. doi: 10.1016/j.mod.2018.08.009. Epub 2018 Aug 23.

3.

Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life.

Roelink H.

J Dev Biol. 2018 Jun 8;6(2). pii: E12. doi: 10.3390/jdb6020012. Review.

4.

Skin-Derived Vitamin D3 Protects against Basal Cell Carcinoma.

Bijlsma MF, Roelink H.

J Invest Dermatol. 2017 Dec;137(12):2469-2471. doi: 10.1016/j.jid.2017.07.816.

5.

Patched1 and Patched2 inhibit Smoothened non-cell autonomously.

Roberts B, Casillas C, Alfaro AC, Jägers C, Roelink H.

Elife. 2016 Aug 23;5. pii: e17634. doi: 10.7554/eLife.17634.

6.

A Multicenter Randomized Noninferiority Trial Comparing GreenLight-XPS Laser Vaporization of the Prostate and Transurethral Resection of the Prostate for the Treatment of Benign Prostatic Obstruction: Two-yr Outcomes of the GOLIATH Study.

Thomas JA, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyère F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitán C, Knispel H, Bachmann A.

Eur Urol. 2016 Jan;69(1):94-102. doi: 10.1016/j.eururo.2015.07.054. Epub 2015 Aug 15.

PMID:
26283011
7.

A European multicenter randomized noninferiority trial comparing 180 W GreenLight XPS laser vaporization and transurethral resection of the prostate for the treatment of benign prostatic obstruction: 12-month results of the GOLIATH study.

Bachmann A, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyère F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitán C, Knispel H, Thomas JA.

J Urol. 2015 Feb;193(2):570-8. doi: 10.1016/j.juro.2014.09.001. Epub 2014 Sep 16.

PMID:
25219699
8.

Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling.

Kwong L, Bijlsma MF, Roelink H.

Nat Commun. 2014 Sep 12;5:4849. doi: 10.1038/ncomms5849.

9.

Ptch2 mediates the Shh response in Ptch1-/- cells.

Alfaro AC, Roberts B, Kwong L, Bijlsma MF, Roelink H.

Development. 2014 Sep;141(17):3331-9. doi: 10.1242/dev.110056. Epub 2014 Aug 1.

10.

Core promoter factor TAF9B regulates neuronal gene expression.

Herrera FJ, Yamaguchi T, Roelink H, Tjian R.

Elife. 2014 Jul 8;3:e02559. doi: 10.7554/eLife.02559.

11.

180-W XPS GreenLight laser vaporisation versus transurethral resection of the prostate for the treatment of benign prostatic obstruction: 6-month safety and efficacy results of a European Multicentre Randomised Trial--the GOLIATH study.

Bachmann A, Tubaro A, Barber N, d'Ancona F, Muir G, Witzsch U, Grimm MO, Benejam J, Stolzenburg JU, Riddick A, Pahernik S, Roelink H, Ameye F, Saussine C, Bruyère F, Loidl W, Larner T, Gogoi NK, Hindley R, Muschter R, Thorpe A, Shrotri N, Graham S, Hamann M, Miller K, Schostak M, Capitán C, Knispel H, Thomas JA.

Eur Urol. 2014 May;65(5):931-42. doi: 10.1016/j.eururo.2013.10.040. Epub 2013 Nov 11.

PMID:
24331152
12.

Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.

Damhofer H, Medema JP, Veenstra VL, Badea L, Popescu I, Roelink H, Bijlsma MF.

Mol Oncol. 2013 Dec;7(6):1031-42. doi: 10.1016/j.molonc.2013.08.004. Epub 2013 Aug 16.

13.

Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.

Bijlsma MF, Damhofer H, Roelink H.

Sci Signal. 2012 Aug 21;5(238):ra60. doi: 10.1126/scisignal.2002798.

14.

Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube.

Shum AS, Tang LS, Copp AJ, Roelink H.

Dev Dyn. 2010 Dec;239(12):3192-203. doi: 10.1002/dvdy.22457. Epub 2010 Oct 19.

15.

Non-cell-autonomous signaling by Shh in tumors: challenges and opportunities for therapeutic targets.

Bijlsma MF, Roelink H.

Expert Opin Ther Targets. 2010 Jul;14(7):693-702. doi: 10.1517/14728222.2010.497488. Review.

PMID:
20515293
16.

Evidence for a role of vertebrate Disp1 in long-range Shh signaling.

Etheridge LA, Crawford TQ, Zhang S, Roelink H.

Development. 2010 Jan;137(1):133-40. doi: 10.1242/dev.043547.

17.

Sonic hedgehog is required for the assembly and remodeling of branchial arch blood vessels.

Kolesová H, Roelink H, Grim M.

Dev Dyn. 2008 Jul;237(7):1923-34. doi: 10.1002/dvdy.21608.

18.

Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation.

Bijlsma MF, Peppelenbosch MP, Spek CA, Roelink H.

Stem Cells. 2008 May;26(5):1138-45. doi: 10.1634/stemcells.2007-0841. Epub 2008 Feb 21.

19.

Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites.

Bijlsma MF, Borensztajn KS, Roelink H, Peppelenbosch MP, Spek CA.

Cell Signal. 2007 Dec;19(12):2596-604. Epub 2007 Aug 24.

PMID:
17884337
21.

Inhibition of cGMP-dependent protein kinase reduces the response to sonic hedgehog in neuralized embryoid bodies.

Christensen C, Zhang S, Roelink H.

Stem Cells Dev. 2006 Oct;15(5):647-54.

PMID:
17105400
22.
23.

Nude thymic rudiment lacking functional foxn1 resembles respiratory epithelium.

Dooley J, Erickson M, Roelink H, Farr AG.

Dev Dyn. 2005 Aug;233(4):1605-12.

24.

Sonic hedgehog patterning in chick neural plate is antagonized by a Wnt3-like signal.

Robertson CP, Braun MM, Roelink H.

Dev Dyn. 2004 Mar;229(3):510-9.

25.

Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain.

Braun MM, Etheridge A, Bernard A, Robertson CP, Roelink H.

Development. 2003 Dec;130(23):5579-87. Epub 2003 Oct 1.

27.

Sonic hedgehog induces the segregation of patched and smoothened in endosomes.

Incardona JP, Gruenberg J, Roelink H.

Curr Biol. 2002 Jun 25;12(12):983-95.

28.

Protein kinase A deficiency causes axially localized neural tube defects in mice.

Huang Y, Roelink H, McKnight GS.

J Biol Chem. 2002 May 31;277(22):19889-96. Epub 2002 Mar 8.

29.

cGMP enhances the sonic hedgehog response in neural plate cells.

Robertson CP, Gibbs SM, Roelink H.

Dev Biol. 2001 Oct 1;238(1):157-67.

30.

Hippocampus formation: an intriguing collaboration.

Roelink H.

Curr Biol. 2000 Apr 6;10(7):R279-81. Review.

31.

The role of cholesterol in Shh signaling and teratogen-induced holoprosencephaly.

Incardona JP, Roelink H.

Cell Mol Life Sci. 2000 Nov;57(12):1709-19. Review.

PMID:
11130177
32.

Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1.

Incardona JP, Lee JH, Robertson CP, Enga K, Kapur RP, Roelink H.

Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12044-9.

33.

Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport.

Incardona JP, Gaffield W, Lange Y, Cooney A, Pentchev PG, Liu S, Watson JA, Kapur RP, Roelink H.

Dev Biol. 2000 Aug 15;224(2):440-52.

34.

A looking glass perspective: thalidomide and cyclopamine.

Gaffield W, Incardona JP, Kapur RP, Roelink H.

Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):579-88. Review.

PMID:
10512190
36.

WNT signaling in the control of hair growth and structure.

Millar SE, Willert K, Salinas PC, Roelink H, Nusse R, Sussman DJ, Barsh GS.

Dev Biol. 1999 Mar 1;207(1):133-49.

37.

The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

Incardona JP, Gaffield W, Kapur RP, Roelink H.

Development. 1998 Sep;125(18):3553-62.

38.

Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro.

Levine EM, Roelink H, Turner J, Reh TA.

J Neurosci. 1997 Aug 15;17(16):6277-88.

39.

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity.

Ericson J, Morton S, Kawakami A, Roelink H, Jessell TM.

Cell. 1996 Nov 15;87(4):661-73.

40.

Determination of neuroepithelial cell fate: induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog.

Pringle NP, Yu WP, Guthrie S, Roelink H, Lumsden A, Peterson AC, Richardson WD.

Dev Biol. 1996 Jul 10;177(1):30-42.

41.
42.

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm.

Liem KF Jr, Tremml G, Roelink H, Jessell TM.

Cell. 1995 Sep 22;82(6):969-79.

43.

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation.

Tanabe Y, Roelink H, Jessell TM.

Curr Biol. 1995 Jun 1;5(6):651-8.

44.

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis.

Roelink H, Porter JA, Chiang C, Tanabe Y, Chang DT, Beachy PA, Jessell TM.

Cell. 1995 May 5;81(3):445-55.

45.

Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos.

Ruiz i Altaba A, Jessell TM, Roelink H.

Mol Cell Neurosci. 1995 Apr;6(2):106-21.

PMID:
7551564
46.

Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

Roelink H, Augsburger A, Heemskerk J, Korzh V, Norlin S, Ruiz i Altaba A, Tanabe Y, Placzek M, Edlund T, Jessell TM, et al.

Cell. 1994 Feb 25;76(4):761-75.

PMID:
8124714
47.

Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene.

Roelink H, Wang J, Black DM, Solomon E, Nusse R.

Genomics. 1993 Sep;17(3):790-2.

PMID:
8244403
48.
50.

Supplemental Content

Loading ...
Support Center