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Items: 38

1.

Opposing Roles of apolipoprotein E in aging and neurodegeneration.

Hudry E, Klickstein J, Cannavo C, Jackson R, Muzikansky A, Gandhi S, Urick D, Sargent T, Wrobleski L, Roe AD, Hou SS, Kuchibhotla KV, Betensky RA, Spires-Jones T, Hyman BT.

Life Sci Alliance. 2019 Feb 13;2(1). pii: e201900325. doi: 10.26508/lsa.201900325. Print 2019 Feb.

2.

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease.

Hopp SC, Lin Y, Oakley D, Roe AD, DeVos SL, Hanlon D, Hyman BT.

J Neuroinflammation. 2018 Sep 18;15(1):269. doi: 10.1186/s12974-018-1309-z.

3.

β-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals.

Wu HY, Kuo PC, Wang YT, Lin HT, Roe AD, Wang BY, Han CL, Hyman BT, Chen YJ, Tai HC.

J Neuropathol Exp Neurol. 2018 Sep 1;77(9):814-826. doi: 10.1093/jnen/nly059.

PMID:
30016458
4.

A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type.

Kara E, Marks JD, Roe AD, Commins C, Fan Z, Calvo-Rodriguez M, Wegmann S, Hudry E, Hyman BT.

J Biol Chem. 2018 Aug 24;293(34):13247-13256. doi: 10.1074/jbc.RA117.001388. Epub 2018 Jun 27.

PMID:
29950521
5.

Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo.

DeVos SL, Corjuc BT, Commins C, Dujardin S, Bannon RN, Corjuc D, Moore BD, Bennett RE, Jorfi M, Gonzales JA, Dooley PM, Roe AD, Pitstick R, Irimia D, Frosch MP, Carlson GA, Hyman BT.

Brain. 2018 Jul 1;141(7):2194-2212. doi: 10.1093/brain/awy117.

PMID:
29733334
7.

Tau protein liquid-liquid phase separation can initiate tau aggregation.

Wegmann S, Eftekharzadeh B, Tepper K, Zoltowska KM, Bennett RE, Dujardin S, Laskowski PR, MacKenzie D, Kamath T, Commins C, Vanderburg C, Roe AD, Fan Z, Molliex AM, Hernandez-Vega A, Muller D, Hyman AA, Mandelkow E, Taylor JP, Hyman BT.

EMBO J. 2018 Apr 3;37(7). pii: e98049. doi: 10.15252/embj.201798049. Epub 2018 Feb 22.

8.

Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay.

Kara E, Marks JD, Fan Z, Klickstein JA, Roe AD, Krogh KA, Wegmann S, Maesako M, Luo CC, Mylvaganam R, Berezovska O, Hudry E, Hyman BT.

J Biol Chem. 2017 Sep 8;292(36):14720-14729. doi: 10.1074/jbc.M117.784264. Epub 2017 Jul 6.

9.

Characterization of TauC3 antibody and demonstration of its potential to block tau propagation.

Nicholls SB, DeVos SL, Commins C, Nobuhara C, Bennett RE, Corjuc DL, Maury E, Eftekharzadeh B, Akingbade O, Fan Z, Roe AD, Takeda S, Wegmann S, Hyman BT.

PLoS One. 2017 May 22;12(5):e0177914. doi: 10.1371/journal.pone.0177914. eCollection 2017.

10.

Enhanced Tau Aggregation in the Presence of Amyloid β.

Bennett RE, DeVos SL, Dujardin S, Corjuc B, Gor R, Gonzalez J, Roe AD, Frosch MP, Pitstick R, Carlson GA, Hyman BT.

Am J Pathol. 2017 Jul;187(7):1601-1612. doi: 10.1016/j.ajpath.2017.03.011. Epub 2017 May 10.

11.

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.

Nobuhara CK, DeVos SL, Commins C, Wegmann S, Moore BD, Roe AD, Costantino I, Frosch MP, Pitstick R, Carlson GA, Hock C, Nitsch RM, Montrasio F, Grimm J, Cheung AE, Dunah AW, Wittmann M, Bussiere T, Weinreb PH, Hyman BT, Takeda S.

Am J Pathol. 2017 Jun;187(6):1399-1412. doi: 10.1016/j.ajpath.2017.01.022. Epub 2017 Apr 11.

12.

Genetic and genomic evidence of niche partitioning and adaptive radiation in mountain pine beetle fungal symbionts.

Ojeda Alayon DI, Tsui CK, Feau N, Capron A, Dhillon B, Zhang Y, Massoumi Alamouti S, Boone CK, Carroll AL, Cooke JE, Roe AD, Sperling FA, Hamelin RC.

Mol Ecol. 2017 Apr;26(7):2077-2091. doi: 10.1111/mec.14074. Epub 2017 Mar 22.

PMID:
28231417
13.

Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly.

Chhatwal JP, Schultz AP, Marshall GA, Boot B, Gomez-Isla T, Dumurgier J, LaPoint M, Scherzer C, Roe AD, Hyman BT, Sperling RA, Johnson KA.

Neurology. 2016 Aug 30;87(9):920-6. doi: 10.1212/WNL.0000000000003050. Epub 2016 Jul 29.

14.

Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.

Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, Raskind MA, Li G, Montine TJ, Frosch MP, Hyman BT.

Ann Neurol. 2016 Sep;80(3):355-67. doi: 10.1002/ana.24716. Epub 2016 Aug 3.

15.

Early detection of cryptic memory and glucose uptake deficits in pre-pathological APP mice.

Beglopoulos V, Tulloch J, Roe AD, Daumas S, Ferrington L, Watson R, Fan Z, Hyman BT, Kelly PA, Bard F, Morris RG.

Nat Commun. 2016 Jun 1;7:11761. doi: 10.1038/ncomms11761.

16.

Modeling Landscape-Level Spatial Variation in Sex Ratio Skew in the Mountain Pine Beetle (Coleoptera: Curculionidae).

James PM, Janes JK, Roe AD, Cooke BJ.

Environ Entomol. 2016 Aug;45(4):790-801. doi: 10.1093/ee/nvw048. Epub 2016 May 21.

PMID:
27209334
17.

Polygamy and an absence of fine-scale structure in Dendroctonus ponderosae (Hopk.) (Coleoptera: Curcilionidae) confirmed using molecular markers.

Janes JK, Roe AD, Rice AV, Gorrell JC, Coltman DW, Langor DW, Sperling FA.

Heredity (Edinb). 2016 Jan;116(1):124. doi: 10.1038/hdy.2015.87. No abstract available.

18.

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain.

Takeda S, Wegmann S, Cho H, DeVos SL, Commins C, Roe AD, Nicholls SB, Carlson GA, Pitstick R, Nobuhara CK, Costantino I, Frosch MP, Müller DJ, Irimia D, Hyman BT.

Nat Commun. 2015 Oct 13;6:8490. doi: 10.1038/ncomms9490.

19.

Polygamy and an absence of fine-scale structure in Dendroctonus ponderosae (Hopk.) (Coleoptera: Curcilionidae) confirmed using molecular markers.

Janes JK, Roe AD, Rice AV, Gorrell JC, Coltman DW, Langor DW, Sperling FA.

Heredity (Edinb). 2016 Jan;116(1):68-74. doi: 10.1038/hdy.2015.71. Epub 2015 Aug 19. Erratum in: Heredity (Edinb). 2016 Jan;116(1):124.

20.

Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease.

Campbell SN, Zhang C, Roe AD, Lee N, Lao KU, Monte L, Donohue MC, Rissman RA.

J Alzheimers Dis. 2015;45(4):1175-84. doi: 10.3233/JAD-142844.

21.

Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials.

Donohue MC, Moghadam SH, Roe AD, Sun CK, Edland SD, Thomas RG, Petersen RC, Sano M, Galasko D, Aisen PS, Rissman RA.

Alzheimers Dement. 2015 Sep;11(9):1069-79. doi: 10.1016/j.jalz.2014.07.156. Epub 2014 Oct 7.

22.

Population structure of mountain pine beetle symbiont Leptographium longiclavatum and the implication on the multipartite beetle-fungi relationships.

Tsui CK, Farfan L, Roe AD, Rice AV, Cooke JE, El-Kassaby YA, Hamelin RC.

PLoS One. 2014 Aug 25;9(8):e105455. doi: 10.1371/journal.pone.0105455. eCollection 2014.

23.

Increased tau phosphorylation and aggregation in the hippocampus of mice overexpressing corticotropin-releasing factor.

Campbell SN, Zhang C, Monte L, Roe AD, Rice KC, Taché Y, Masliah E, Rissman RA.

J Alzheimers Dis. 2015;43(3):967-76. doi: 10.3233/JAD-141281.

24.

Fitness dynamics within a poplar hybrid zone: I. Prezygotic and postzygotic barriers impacting a native poplar hybrid stand.

Roe AD, MacQuarrie CJ, Gros-Louis MC, Simpson JD, Lamarche J, Beardmore T, Thompson SL, Tanguay P, Isabel N.

Ecol Evol. 2014 May;4(9):1629-47. doi: 10.1002/ece3.1029. Epub 2014 Apr 3.

25.

Fitness dynamics within a poplar hybrid zone: II. Impact of exotic sex on native poplars in an urban jungle.

Roe AD, MacQuarrie CJ, Gros-Louis MC, Simpson JD, Lamarche J, Beardmore T, Thompson SL, Tanguay P, Isabel N.

Ecol Evol. 2014 May;4(10):1876-89. doi: 10.1002/ece3.1028. Epub 2014 Apr 19.

26.

Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain.

Hudry E, Dashkoff J, Roe AD, Takeda S, Koffie RM, Hashimoto T, Scheel M, Spires-Jones T, Arbel-Ornath M, Betensky R, Davidson BL, Hyman BT.

Sci Transl Med. 2013 Nov 20;5(212):212ra161. doi: 10.1126/scitranslmed.3007000.

27.

Reversal of neurofibrillary tangles and tau-associated phenotype in the rTgTauEC model of early Alzheimer's disease.

Polydoro M, de Calignon A, Suárez-Calvet M, Sanchez L, Kay KR, Nicholls SB, Roe AD, Pitstick R, Carlson GA, Gómez-Isla T, Spires-Jones TL, Hyman BT.

J Neurosci. 2013 Aug 14;33(33):13300-11. doi: 10.1523/JNEUROSCI.0881-13.2013.

28.

Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.

Takeda S, Hashimoto T, Roe AD, Hori Y, Spires-Jones TL, Hyman BT.

FASEB J. 2013 Aug;27(8):3239-48. doi: 10.1096/fj.13-229666. Epub 2013 May 2.

29.

Multi-locus species delimitation in closely related animals and fungi: one marker is not enough.

Dupuis JR, Roe AD, Sperling FA.

Mol Ecol. 2012 Sep;21(18):4422-36. doi: 10.1111/j.1365-294X.2012.05642.x. Epub 2012 Aug 14. Review.

PMID:
22891635
30.

Phylogeographic insights into an irruptive pest outbreak.

Cullingham CI, Roe AD, Sperling FA, Coltman DW.

Ecol Evol. 2012 May;2(5):908-19. doi: 10.1002/ece3.102.

31.

Population structure and migration pattern of a conifer pathogen, Grosmannia clavigera, as influenced by its symbiont, the mountain pine beetle.

Tsui CK, Roe AD, El-Kassaby YA, Rice AV, Alamouti SM, Sperling FA, Cooke JE, Bohlmann J, Hamelin RC.

Mol Ecol. 2012 Jan;21(1):71-86. doi: 10.1111/j.1365-294X.2011.05366.x. Epub 2011 Nov 25.

PMID:
22118059
32.

Lipopolysaccharide-induced tau phosphorylation and kinase activity--modulation, but not mediation, by corticotropin-releasing factor receptors.

Roe AD, Staup MA, Serrats J, Sawchenko PE, Rissman RA.

Eur J Neurosci. 2011 Aug;34(3):448-56. doi: 10.1111/j.1460-9568.2011.07764.x. Epub 2011 Jul 4.

33.

Multilocus species identification and fungal DNA barcoding: insights from blue stain fungal symbionts of the mountain pine beetle.

Roe AD, Rice AV, Bromilow SE, Cooke JE, Sperling FA.

Mol Ecol Resour. 2010 Nov;10(6):946-59. doi: 10.1111/j.1755-0998.2010.02844.x.

PMID:
21565104
34.

Spatial community structure of mountain pine beetle fungal symbionts across a latitudinal gradient.

Roe AD, James PM, Rice AV, Cooke JE, Sperling FA.

Microb Ecol. 2011 Aug;62(2):347-60. doi: 10.1007/s00248-011-9841-8. Epub 2011 Apr 6.

35.

Comparative phylogeography, genetic differentiation and contrasting reproductive modes in three fungal symbionts of a multipartite bark beetle symbiosis.

Roe AD, Rice AV, Coltman DW, Cooke JE, Sperling FA.

Mol Ecol. 2011 Feb;20(3):584-600. doi: 10.1111/j.1365-294X.2010.04953.x. Epub 2010 Dec 16.

PMID:
21166729
36.

Isolation and characterization of 16 microsatellite loci in the mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae: Scolytinae).

Davis CS, Mock KE, Bentz BJ, Bromilow SM, Bartell NV, Murray BW, Roe AD, Cooke JE.

Mol Ecol Resour. 2009 May;9(3):1071-3. doi: 10.1111/j.1755-0998.2009.02579.x. Epub 2009 Mar 2.

PMID:
21564842
37.
38.

Patterns of evolution of mitochondrial cytochrome c oxidase I and II DNA and implications for DNA barcoding.

Roe AD, Sperling FA.

Mol Phylogenet Evol. 2007 Jul;44(1):325-45. Epub 2006 Dec 20.

PMID:
17270468

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