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Items: 41


Dexmedetomidine implementation in pain management in the immediate postoperative period of cardiac surgery.

Nacher-Fuentes L, Sanchez-Pujol A, Rodriguez-Navarro S, Duran-Ayra L.

Enferm Intensiva. 2019 Nov 3. pii: S1130-2399(19)30064-1. doi: 10.1016/j.enfi.2019.03.006. [Epub ahead of print] English, Spanish.


Mip6 binds directly to the Mex67 UBA domain to maintain low levels of Msn2/4 stress-dependent mRNAs.

Martín-Expósito M, Gas ME, Mohamad N, Nuño-Cabanes C, Tejada-Colón A, Pascual-García P, de la Fuente L, Chaves-Arquero B, Merran J, Corden J, Conesa A, Pérez-Cañadillas JM, Bravo J, Rodríguez-Navarro S.

EMBO Rep. 2019 Dec 5;20(12):e47964. doi: 10.15252/embr.201947964. Epub 2019 Nov 3.


A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export.

Oliete-Calvo P, Serrano-Quílez J, Nuño-Cabanes C, Pérez-Martínez ME, Soares LM, Dichtl B, Buratowski S, Pérez-Ortín JE, Rodríguez-Navarro S.

EMBO Rep. 2018 Nov;19(11). pii: e45992. doi: 10.15252/embr.201845992. Epub 2018 Sep 24.


Corrigendum: SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification.

Tardaguila M, de la Fuente L, Marti C, Pereira C, Pardo-Palacios FJ, Del Risco H, Ferrell M, Mellado M, Macchietto M, Verheggen K, Edelmann M, Ezkurdia I, Vazquez J, Tress M, Mortazavi A, Martens L, Rodriguez-Navarro S, Moreno-Manzano V, Conesa A.

Genome Res. 2018 Jul;28(7):1096. doi: 10.1101/gr.239137.118. No abstract available.


An exon three-way junction structure modulates splicing and degradation of the SUS1 yeast pre-mRNA.

AbuQattam A, Serrano-Quílez J, Rodríguez-Navarro S, Gallego J.

Biochim Biophys Acta Gene Regul Mech. 2018 Aug;1861(8):673-686. doi: 10.1016/j.bbagrm.2018.06.009. Epub 2018 Jul 14.


The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally.

García-Molinero V, García-Martínez J, Reja R, Furió-Tarí P, Antúnez O, Vinayachandran V, Conesa A, Pugh BF, Pérez-Ortín JE, Rodríguez-Navarro S.

Epigenetics Chromatin. 2018 Mar 29;11(1):13. doi: 10.1186/s13072-018-0184-2.


SQANTI: extensive characterization of long-read transcript sequences for quality control in full-length transcriptome identification and quantification.

Tardaguila M, de la Fuente L, Marti C, Pereira C, Pardo-Palacios FJ, Del Risco H, Ferrell M, Mellado M, Macchietto M, Verheggen K, Edelmann M, Ezkurdia I, Vazquez J, Tress M, Mortazavi A, Martens L, Rodriguez-Navarro S, Moreno-Manzano V, Conesa A.

Genome Res. 2018 Feb 9. doi: 10.1101/gr.222976.117. [Epub ahead of print] Erratum in: Genome Res. 2018 Jul;28(7):1096.


The evolutionarily conserved factor Sus1/ENY2 plays a role in telomere length maintenance.

Galán A, García-Oliver E, Nuño-Cabanes C, Rubinstein L, Kupiec M, Rodríguez-Navarro S.

Curr Genet. 2018 Jun;64(3):635-644. doi: 10.1007/s00294-017-0778-4. Epub 2017 Nov 7.


Morphofunctional Changes After Sleeve Gastrectomy and Very Low Calorie Diet in an Animal Model of Non-Alcoholic Fatty Liver Disease.

Talavera-Urquijo E, Rodríguez-Navarro S, Beisani M, Salcedo-Allende MT, Chakkur A, Arús-Avilés M, Cremades M, Augustin S, Martell M, Balibrea JM.

Obes Surg. 2018 Jan;28(1):142-151. doi: 10.1007/s11695-017-2805-4.


An intronic RNA structure modulates expression of the mRNA biogenesis factor Sus1.

AbuQattam A, Gallego J, Rodríguez-Navarro S.

RNA. 2016 Jan;22(1):75-86. doi: 10.1261/rna.054049.115. Epub 2015 Nov 6.


Unveiling novel interactions of histone chaperone Asf1 linked to TREX-2 factors Sus1 and Thp1.

Pamblanco M, Oliete-Calvo P, García-Oliver E, Luz Valero M, Sanchez del Pino MM, Rodríguez-Navarro S.

Nucleus. 2014 May-Jun;5(3):247-59. doi: 10.4161/nucl.29155. Epub 2014 May 13.


Optimised protocols for the metabolic profiling of S. cerevisiae by 1H-NMR and HRMAS spectroscopy.

Palomino-Schätzlein M, Molina-Navarro MM, Tormos-Pérez M, Rodríguez-Navarro S, Pineda-Lucena A.

Anal Bioanal Chem. 2013 Oct;405(26):8431-41. doi: 10.1007/s00216-013-7271-9. Epub 2013 Aug 14.


The Hog1 stress-activated protein kinase targets nucleoporins to control mRNA export upon stress.

Regot S, de Nadal E, Rodríguez-Navarro S, González-Novo A, Pérez-Fernandez J, Gadal O, Seisenbacher G, Ammerer G, Posas F.

J Biol Chem. 2013 Jun 14;288(24):17384-98. doi: 10.1074/jbc.M112.444042. Epub 2013 May 3. Erratum in: J Biol Chem. 2015 Jan 23;290(4):2301.


A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA.

García-Oliver E, Pascual-García P, García-Molinero V, Lenstra TL, Holstege FC, Rodríguez-Navarro S.

Nucleic Acids Res. 2013 Jun;41(11):5655-68. doi: 10.1093/nar/gkt272. Epub 2013 Apr 17.


The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner.

Mirón-García MC, Garrido-Godino AI, García-Molinero V, Hernández-Torres F, Rodríguez-Navarro S, Navarro F.

PLoS Genet. 2013;9(2):e1003297. doi: 10.1371/journal.pgen.1003297. Epub 2013 Feb 14.


Comparison of global responses to mild deficiency and excess copper levels in Arabidopsis seedlings.

Andrés-Colás N, Perea-García A, Mayo de Andrés S, Garcia-Molina A, Dorcey E, Rodríguez-Navarro S, Pérez-Amador MA, Puig S, Peñarrubia L.

Metallomics. 2013 Sep;5(9):1234-46. doi: 10.1039/c3mt00025g.


Rtp1p is a karyopherin-like protein required for RNA polymerase II biogenesis.

Gómez-Navarro N, Peiró-Chova L, Rodriguez-Navarro S, Polaina J, Estruch F.

Mol Cell Biol. 2013 May;33(9):1756-67. doi: 10.1128/MCB.01449-12. Epub 2013 Feb 25.


Sus1/ENY2: a multitasking protein in eukaryotic gene expression.

Galán A, Rodríguez-Navarro S.

Crit Rev Biochem Mol Biol. 2012 Nov-Dec;47(6):556-68. doi: 10.3109/10409238.2012.730498. Epub 2012 Oct 12. Review.


Nuclear transport and RNA processing.

Rodríguez-Navarro S.

Biochim Biophys Acta. 2012 Jun;1819(6):467. doi: 10.1016/j.bbagrm.2012.04.004. No abstract available.


mRNA export and gene expression: the SAGA-TREX-2 connection.

García-Oliver E, García-Molinero V, Rodríguez-Navarro S.

Biochim Biophys Acta. 2012 Jun;1819(6):555-65. doi: 10.1016/j.bbagrm.2011.11.011. Epub 2011 Dec 8. Review.


SUS1 introns are required for efficient mRNA nuclear export in yeast.

Cuenca-Bono B, García-Molinero V, Pascual-García P, Dopazo H, Llopis A, Vilardell J, Rodríguez-Navarro S.

Nucleic Acids Res. 2011 Oct;39(19):8599-611. doi: 10.1093/nar/gkr496. Epub 2011 Jul 12.


Linking gene regulation to mRNA production and export.

Rodríguez-Navarro S, Hurt E.

Curr Opin Cell Biol. 2011 Jun;23(3):302-9. doi: 10.1016/ Epub 2011 Jan 11. Review.


Transcriptional elongation and mRNA export are coregulated processes.

Molina-Navarro MM, Martinez-Jimenez CP, Rodriguez-Navarro S.

Genet Res Int. 2011;2011:652461. doi: 10.4061/2011/652461. Epub 2011 Oct 5.


A novel link between Sus1 and the cytoplasmic mRNA decay machinery suggests a broad role in mRNA metabolism.

Cuenca-Bono B, García-Molinero V, Pascual-García P, García-Oliver E, Llopis A, Rodríguez-Navarro S.

BMC Cell Biol. 2010 Mar 15;11:19. doi: 10.1186/1471-2121-11-19.


Insights into SAGA function during gene expression.

Rodríguez-Navarro S.

EMBO Rep. 2009 Aug;10(8):843-50. doi: 10.1038/embor.2009.168. Epub 2009 Jul 17. Review.


A tale of coupling, Sus1 function in transcription and mRNA export.

Pascual-García P, Rodríguez-Navarro S.

RNA Biol. 2009 Apr-Jun;6(2):141-4. Epub 2009 Apr 7. Review.


Sus1 is recruited to coding regions and functions during transcription elongation in association with SAGA and TREX2.

Pascual-García P, Govind CK, Queralt E, Cuenca-Bono B, Llopis A, Chavez S, Hinnebusch AG, Rodríguez-Navarro S.

Genes Dev. 2008 Oct 15;22(20):2811-22. doi: 10.1101/gad.483308.


The Cth2 ARE-binding protein recruits the Dhh1 helicase to promote the decay of succinate dehydrogenase SDH4 mRNA in response to iron deficiency.

Pedro-Segura E, Vergara SV, Rodríguez-Navarro S, Parker R, Thiele DJ, Puig S.

J Biol Chem. 2008 Oct 17;283(42):28527-35. doi: 10.1074/jbc.M804910200. Epub 2008 Aug 20.


The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11.

Köhler A, Pascual-García P, Llopis A, Zapater M, Posas F, Hurt E, Rodríguez-Navarro S.

Mol Biol Cell. 2006 Oct;17(10):4228-36. Epub 2006 Jul 19.


SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope.

Cabal GG, Genovesio A, Rodriguez-Navarro S, Zimmer C, Gadal O, Lesne A, Buc H, Feuerbach-Fournier F, Olivo-Marin JC, Hurt EC, Nehrbass U.

Nature. 2006 Jun 8;441(7094):770-3.


The Arabidopsis heavy metal P-type ATPase HMA5 interacts with metallochaperones and functions in copper detoxification of roots.

Andrés-Colás N, Sancenón V, Rodríguez-Navarro S, Mayo S, Thiele DJ, Ecker JR, Puig S, Peñarrubia L.

Plant J. 2006 Jan;45(2):225-36.


Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export.

Estruch F, Hodge CA, Rodríguez-Navarro S, Cole CN.

J Biol Chem. 2005 Mar 11;280(10):9691-7. Epub 2004 Dec 24.


Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery.

Fischer T, Rodríguez-Navarro S, Pereira G, Rácz A, Schiebel E, Hurt E.

Nat Cell Biol. 2004 Sep;6(9):840-8. Epub 2004 Aug 15.


Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery.

Rodríguez-Navarro S, Fischer T, Luo MJ, Antúnez O, Brettschneider S, Lechner J, Pérez-Ortín JE, Reed R, Hurt E.

Cell. 2004 Jan 9;116(1):75-86.


The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores.

Fischer T, Strässer K, Rácz A, Rodriguez-Navarro S, Oppizzi M, Ihrig P, Lechner J, Hurt E.

EMBO J. 2002 Nov 1;21(21):5843-52.


Functional analysis of yeast gene families involved in metabolism of vitamins B1 and B6.

Rodríguez-Navarro S, Llorente B, Rodríguez-Manzaneque MT, Ramne A, Uber G, Marchesan D, Dujon B, Herrero E, Sunnerhagen P, Pérez-Ortín JE.

Yeast. 2002 Oct;19(14):1261-76.


TREX is a conserved complex coupling transcription with messenger RNA export.

Strässer K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondón AG, Aguilera A, Struhl K, Reed R, Hurt E.

Nature. 2002 May 16;417(6886):304-8. Epub 2002 Apr 28.


An intron in the YRA1 gene is required to control Yra1 protein expression and mRNA export in yeast.

Rodríguez-Navarro S, Strässer K, Hurt E.

EMBO Rep. 2002 May;3(5):438-42. Epub 2002 Apr 18.


SRC1: an intron-containing yeast gene involved in sister chromatid segregation.

Rodríguez-Navarro S, Igual JC, Pérez-Ortín JE.

Yeast. 2002 Jan 15;19(1):43-54.


Bromodomain factor 1 (Bdf1) protein interacts with histones.

Pamblanco M, Poveda A, Sendra R, Rodríguez-Navarro S, Pérez-Ortín JE, Tordera V.

FEBS Lett. 2001 May 4;496(1):31-5.


Functional analysis of 12 ORFs from Saccharomyces cerevisiae chromosome II.

Rodríguez-Navarro S, Estruch F, Pérez-Ortín JE.

Yeast. 1999 Jul;15(10B):913-9.

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