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Items: 13


The role of telomere shortening in carcinogenesis: A hybrid stochastic-deterministic approach.

Rodriguez-Brenes IA, Komarova NL, Wodarz D.

J Theor Biol. 2019 Jan 7;460:144-152. doi: 10.1016/j.jtbi.2018.09.003. Epub 2018 Oct 10.


Cellular Hierarchy as a Determinant of Tumor Sensitivity to Chemotherapy.

Rodriguez-Brenes IA, Kurtova AV, Lin C, Lee YC, Xiao J, Mims M, Chan KS, Wodarz D.

Cancer Res. 2017 May 1;77(9):2231-2241. doi: 10.1158/0008-5472.CAN-16-2434. Epub 2017 Feb 24.


Complex Dynamics of Virus Spread from Low Infection Multiplicities: Implications for the Spread of Oncolytic Viruses.

Rodriguez-Brenes IA, Hofacre A, Fan H, Wodarz D.

PLoS Comput Biol. 2017 Jan 20;13(1):e1005241. doi: 10.1371/journal.pcbi.1005241. eCollection 2017 Jan. Erratum in: PLoS Comput Biol. 2017 May 19;13(5):e1005548.


Telomeres open a window on stem cell division.

Rodriguez-Brenes IA, Wodarz D.

Elife. 2016 Jan 25;5:e12481. doi: 10.7554/eLife.12481.


Quantifying replicative senescence as a tumor suppressor pathway and a target for cancer therapy.

Rodriguez-Brenes IA, Wodarz D, Komarova NL.

Sci Rep. 2015 Dec 9;5:17660. doi: 10.1038/srep17660.


Characterizing inhibited tumor growth in stem-cell-driven non-spatial cancers.

Rodriguez-Brenes IA, Wodarz D, Komarova NL.

Math Biosci. 2015 Dec;270(Pt A):135-41. doi: 10.1016/j.mbs.2015.08.009. Epub 2015 Sep 4.


Preventing clonal evolutionary processes in cancer: Insights from mathematical models.

Rodriguez-Brenes IA, Wodarz D.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):8843-50. doi: 10.1073/pnas.1501730112.


Cancer-associated mutations in healthy individuals: assessing the risk of carcinogenesis.

Rodriguez-Brenes IA, Komarova NL, Wodarz D.

Cancer Res. 2014 Mar 15;74(6):1661-9. doi: 10.1158/0008-5472.CAN-13-1452. Epub 2014 Jan 22.


Minimizing the risk of cancer: tissue architecture and cellular replication limits.

Rodriguez-Brenes IA, Wodarz D, Komarova NL.

J R Soc Interface. 2013 Jul 3;10(86):20130410. doi: 10.1098/rsif.2013.0410. Print 2013 Sep 6.


Tumor growth dynamics: insights into evolutionary processes.

Rodriguez-Brenes IA, Komarova NL, Wodarz D.

Trends Ecol Evol. 2013 Oct;28(10):597-604. doi: 10.1016/j.tree.2013.05.020. Epub 2013 Jun 28. Review.


Stem cell control, oscillations, and tissue regeneration in spatial and non-spatial models.

Rodriguez-Brenes IA, Wodarz D, Komarova NL.

Front Oncol. 2013 Apr 15;3:82. doi: 10.3389/fonc.2013.00082. eCollection 2013.


Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers.

Rodriguez-Brenes IA, Komarova NL, Wodarz D.

Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):18983-8. doi: 10.1073/pnas.1107621108. Epub 2011 Nov 14.


Quantitative theory of telomere length regulation and cellular senescence.

Rodriguez-Brenes IA, Peskin CS.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5387-92. doi: 10.1073/pnas.0914502107. Epub 2010 Mar 5.

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