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Items: 32

1.

Time series modeling of cell cycle exit identifies Brd4 dependent regulation of cerebellar neurogenesis.

Penas C, Maloof ME, Stathias V, Long J, Tan SK, Mier J, Fang Y, Valdes C, Rodriguez-Blanco J, Chiang CM, Robbins DJ, Liebl DJ, Lee JK, Hatten ME, Clarke J, Ayad NG.

Nat Commun. 2019 Jul 10;10(1):3028. doi: 10.1038/s41467-019-10799-5.

2.

A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.

Rodriguez-Blanco J, Li B, Long J, Shen C, Yang F, Orton D, Collins S, Kasahara N, Ayad NG, McCrea HJ, Roussel MF, Weiss WA, Capobianco AJ, Robbins DJ.

Clin Cancer Res. 2019 Feb 15;25(4):1379-1388. doi: 10.1158/1078-0432.CCR-18-1319. Epub 2018 Nov 28.

PMID:
30487124
3.

Organic synthesis on Mars by electrochemical reduction of CO2.

Steele A, Benning LG, Wirth R, Siljeström S, Fries MD, Hauri E, Conrad PG, Rogers K, Eigenbrode J, Schreiber A, Needham A, Wang JH, McCubbin FM, Kilcoyne D, Rodriguez Blanco JD.

Sci Adv. 2018 Oct 31;4(10):eaat5118. doi: 10.1126/sciadv.aat5118. eCollection 2018 Oct.

4.

Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.

Rodriguez-Blanco J, Pednekar L, Penas C, Li B, Martin V, Long J, Lee E, Weiss WA, Rodriguez C, Mehrdad N, Nguyen DM, Ayad NG, Rai P, Capobianco AJ, Robbins DJ.

Oncogene. 2017 Nov 9;36(45):6306-6314. doi: 10.1038/onc.2017.232. Epub 2017 Jul 17.

5.

Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.

Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ.

Sci Signal. 2017 Jun 27;10(485). pii: eaak9916. doi: 10.1126/scisignal.aak9916.

6.

The role of amorphous precursors in the crystallization of La and Nd carbonates.

Vallina B, Rodriguez-Blanco JD, Brown AP, Blanco JA, Benning LG.

Nanoscale. 2015 Jul 28;7(28):12166-79. doi: 10.1039/c5nr01497b. Epub 2015 Jul 1.

7.

Biomineralisation by earthworms - an investigation into the stability and distribution of amorphous calcium carbonate.

Hodson ME, Benning LG, Demarchi B, Penkman KE, Rodriguez-Blanco JD, Schofield PF, Versteegh EA.

Geochem Trans. 2015 Apr 28;16:4. eCollection 2015.

8.

The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.

Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ.

J Biol Chem. 2014 Dec 19;289(51):35494-502. doi: 10.1074/jbc.M114.595348. Epub 2014 Oct 29.

9.

Pyrvinium attenuates Hedgehog signaling downstream of smoothened.

Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, Robbins DJ.

Cancer Res. 2014 Sep 1;74(17):4811-21. doi: 10.1158/0008-5472.CAN-14-0317. Epub 2014 Jul 3.

10.

Mechanisms involved in the pro-apoptotic effect of melatonin in cancer cells.

Rodriguez C, Martín V, Herrera F, García-Santos G, Rodriguez-Blanco J, Casado-Zapico S, Sánchez-Sánchez AM, Suárez S, Puente-Moncada N, Anítua MJ, Antolín I.

Int J Mol Sci. 2013 Mar 25;14(4):6597-613. doi: 10.3390/ijms14046597. Review.

11.

Hedgehog signaling regulates bladder cancer growth and tumorigenicity.

Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, Bejarano P, Capobianco AJ, Robbins DJ.

Cancer Res. 2012 Sep 1;72(17):4449-58. Epub 2012 Jul 19.

12.

The hedgehog processing pathway is required for NSCLC growth and survival.

Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, Lam WL, Dmitrovsky E, Capobianco AJ, Robbins DJ.

Oncogene. 2013 May 2;32(18):2335-45. doi: 10.1038/onc.2012.243. Epub 2012 Jun 25.

13.

Cooperative action of JNK and AKT/mTOR in 1-methyl-4-phenylpyridinium-induced autophagy of neuronal PC12 cells.

Rodríguez-Blanco J, Martín V, García-Santos G, Herrera F, Casado-Zapico S, Antolín I, Rodriguez C.

J Neurosci Res. 2012 Sep;90(9):1850-60. doi: 10.1002/jnr.23066. Epub 2012 Apr 19.

PMID:
22513717
14.

The role and implications of bassanite as a stable precursor phase to gypsum precipitation.

Van Driessche AE, Benning LG, Rodriguez-Blanco JD, Ossorio M, Bots P, García-Ruiz JM.

Science. 2012 Apr 6;336(6077):69-72. doi: 10.1126/science.1215648.

15.

Fas/Fas ligand regulation mediates cell death in human Ewing's sarcoma cells treated with melatonin.

García-Santos G, Martin V, Rodríguez-Blanco J, Herrera F, Casado-Zapico S, Sánchez-Sánchez AM, Antolín I, Rodríguez C.

Br J Cancer. 2012 Mar 27;106(7):1288-96. doi: 10.1038/bjc.2012.66. Epub 2012 Mar 1.

16.

Intracellular redox state as determinant for melatonin antiproliferative vs cytotoxic effects in cancer cells.

Sánchez-Sánchez AM, Martín V, García-Santos G, Rodríguez-Blanco J, Casado-Zapico S, Suarez-Garnacho S, Antolín I, Rodriguez C.

Free Radic Res. 2011 Nov;45(11-12):1333-41. doi: 10.3109/10715762.2011.623700. Epub 2011 Oct 14.

PMID:
21923620
17.

Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity.

Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ.

Cancer Res. 2011 Jul 1;71(13):4454-63. doi: 10.1158/0008-5472.CAN-10-2313. Epub 2011 May 12.

18.

Regulation of the expression of death receptors and their ligands by melatonin in haematological cancer cell lines and in leukaemia cells from patients.

Casado-Zapico S, Martín V, García-Santos G, Rodríguez-Blanco J, Sánchez-Sánchez AM, Luño E, Suárez C, García-Pedrero JM, Menendez ST, Antolín I, Rodriguez C.

J Pineal Res. 2011 Apr;50(3):345-55. doi: 10.1111/j.1600-079X.2010.00850.x. Epub 2011 Feb 24.

PMID:
21392090
19.

The kinetics and mechanisms of amorphous calcium carbonate (ACC) crystallization to calcite, via vaterite.

Rodriguez-Blanco JD, Shaw S, Benning LG.

Nanoscale. 2011 Jan;3(1):265-71. doi: 10.1039/c0nr00589d. Epub 2010 Nov 10.

PMID:
21069231
20.

Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway.

Casado-Zapico S, Rodriguez-Blanco J, García-Santos G, Martín V, Sánchez-Sánchez AM, Antolín I, Rodriguez C.

J Pineal Res. 2010 Jan;48(1):72-80. doi: 10.1111/j.1600-079X.2009.00727.x.

PMID:
20025643
21.

Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death.

Martín V, García-Santos G, Rodriguez-Blanco J, Casado-Zapico S, Sanchez-Sanchez A, Antolín I, Medina M, Rodriguez C.

Cancer Lett. 2010 Jan 28;287(2):216-23. doi: 10.1016/j.canlet.2009.06.016. Epub 2009 Jul 25.

PMID:
19632770
22.

Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine.

Rodriguez-Blanco J, Martín V, Herrera F, García-Santos G, Antolín I, Rodriguez C.

J Neurochem. 2008 Oct;107(1):127-40. doi: 10.1111/j.1471-4159.2008.05588.x. Epub 2008 Jul 28.

23.

Involvement of protein kinase C in melatonin's oncostatic effect in C6 glioma cells.

Martín V, Herrera F, García-Santos G, Antolín I, Rodriguez-Blanco J, Medina M, Rodriguez C.

J Pineal Res. 2007 Oct;43(3):239-44.

PMID:
17803520
24.

Signaling pathways involved in antioxidant control of glioma cell proliferation.

Martín V, Herrera F, García-Santos G, Antolín I, Rodriguez-Blanco J, Rodriguez C.

Free Radic Biol Med. 2007 Jun 1;42(11):1715-22. Epub 2007 Mar 12.

PMID:
17462539
25.

Removal of cadmium from wastewaters by aragonite shells and the influence of other divalent cations.

Köhler SJ, Cubillas P, Rodríguez-Blanco JD, Bauer C, Prieto M.

Environ Sci Technol. 2007 Jan 1;41(1):112-8.

PMID:
17265935
26.

Melatonin prevents glutamate-induced oxytosis in the HT22 mouse hippocampal cell line through an antioxidant effect specifically targeting mitochondria.

Herrera F, Martin V, García-Santos G, Rodriguez-Blanco J, Antolín I, Rodriguez C.

J Neurochem. 2007 Feb;100(3):736-46.

27.

Tryptamine induces cell death with ultrastructural features of autophagy in neurons and glia: Possible relevance for neurodegenerative disorders.

Herrera F, Martin V, Carrera P, García-Santos G, Rodriguez-Blanco J, Rodriguez C, Antolín I.

Anat Rec A Discov Mol Cell Evol Biol. 2006 Sep;288(9):1026-30.

28.

Melatonin induces apoptosis in human neuroblastoma cancer cells.

García-Santos G, Antolín I, Herrera F, Martín V, Rodriguez-Blanco J, del Pilar Carrera M, Rodriguez C.

J Pineal Res. 2006 Sep;41(2):130-5.

PMID:
16879318
29.

Intracellular signaling pathways involved in the cell growth inhibition of glioma cells by melatonin.

Martín V, Herrera F, Carrera-Gonzalez P, García-Santos G, Antolín I, Rodriguez-Blanco J, Rodriguez C.

Cancer Res. 2006 Jan 15;66(2):1081-8.

30.

Standard curve for housekeeping and target genes: specific criteria for selection of loading control in Northern blot analysis.

Herrera F, Martín V, Antolín I, García-Santos G, Rodríguez-Blanco J, Rodríguez C.

J Biotechnol. 2005 Jun 29;117(4):337-41. Epub 2005 Apr 25.

PMID:
15925716
31.

Intracellular redox state regulation by parthenolide.

Herrera F, Martin V, Rodriguez-Blanco J, García-Santos G, Antolín I, Rodriguez C.

Biochem Biophys Res Commun. 2005 Jul 1;332(2):321-5.

PMID:
15910740
32.

Antioxidant activity and neuroprotective effects of zolpidem and several synthesis intermediates.

García-Santos G, Herrera F, Martín V, Rodriguez-Blanco J, Antolín I, Fernández-Marí F, Rodriguez C.

Free Radic Res. 2004 Dec;38(12):1289-99.

PMID:
15763953

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