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Items: 1 to 50 of 249

1.

YES1 Drives Lung Cancer Growth and Progression and Predicts Sensitivity to Dasatinib.

Garmendia I, Pajares MJ, Hermida-Prado F, Ajona D, Bértolo C, Sainz C, Lavín A, Remírez AB, Valencia K, Moreno H, Ferrer I, Behrens C, Cuadrado M, Paz-Ares L, Bustelo XR, Gil-Bazo I, Alameda D, Lecanda F, Calvo A, Felip E, Sánchez-Céspedes M, Wistuba II, Granda-Diaz R, Rodrigo JP, García-Pedrero JM, Pio R, Montuenga LM, Agorreta J.

Am J Respir Crit Care Med. 2019 Jun 5. doi: 10.1164/rccm.201807-1292OC. [Epub ahead of print]

PMID:
31166114
2.

T4 Laryngeal Cancer With Good Function: Should We Be Reluctant to Treat Without Surgery?

Beitler JJ, Ridge JA, Vermorken JB, Bradford CR, Strojan P, Saba NF, Suárez C, Rodrigo JP, Rinaldo A, Chen AY, Ferlito A.

Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1400-1403. doi: 10.1016/j.ijrobp.2018.03.007. No abstract available.

PMID:
31014779
3.

Prognostic and predictive factors in recurrent and/or metastatic head and neck squamous cell carcinoma: A review of the literature.

Bossi P, Alfieri S, Strojan P, Takes RP, López F, Mäkitie A, Saba NF, Rodrigo JP, Bradford C, Suarez C, Zafereo M, Forastiere AA, Vermorken JB, Quer M, Sanabria A, Simo R, de Bree R, Rinaldo A, Ferlito A.

Crit Rev Oncol Hematol. 2019 May;137:84-91. doi: 10.1016/j.critrevonc.2019.01.018. Epub 2019 Feb 13. Review.

PMID:
31014517
4.

Lectin-like transcript 1 (LLT1) expression is associated with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma.

Santos-Juanes J, Fernández-Vega I, Lorenzo-Herrero S, Sordo-Bahamonde C, Martínez-Camblor P, García-Pedrero JM, Vivanco B, Galache-Osuna C, Vazquez-Lopez F, Gonzalez S, Rodrigo JP.

Arch Dermatol Res. 2019 Jul;311(5):369-376. doi: 10.1007/s00403-019-01916-x. Epub 2019 Apr 6.

PMID:
30955082
5.

Elective neck dissection in oral squamous cell carcinoma: Past, present and future.

de Bree R, Takes RP, Shah JP, Hamoir M, Kowalski LP, Robbins KT, Rodrigo JP, Sanabria A, Medina JE, Rinaldo A, Shaha AR, Silver C, Suárez C, Bernal-Sprekelsen M, Ferlito A.

Oral Oncol. 2019 Mar;90:87-93. doi: 10.1016/j.oraloncology.2019.01.016. Epub 2019 Feb 10. Review.

6.

The Novel Role of SOX2 as an Early Predictor of Cancer Risk in Patients with Laryngeal Precancerous Lesions.

Granda-Díaz R, Menéndez ST, Pedregal Mallo D, Hermida-Prado F, Rodríguez R, Suárez-Fernández L, Vallina A, Sánchez-Canteli M, Rodríguez A, Fernández-García MS, Rodrigo JP, García-Pedrero JM.

Cancers (Basel). 2019 Mar 1;11(3). pii: E286. doi: 10.3390/cancers11030286.

7.

Frequent Alteration of Annexin A9 and A10 in HPV-Negative Head and Neck Squamous Cell Carcinomas: Correlation with the Histopathological Differentiation Grade.

Salom C, Álvarez-Teijeiro S, Fernández MP, Morgan RO, Allonca E, Vallina A, Lorz C, de Villalaín L, Fernández-García MS, Rodrigo JP, García-Pedrero JM.

J Clin Med. 2019 Feb 10;8(2). pii: E229. doi: 10.3390/jcm8020229.

8.

Transoral laser microsurgery for glottic cancer in the elderly: Efficacy and safety.

Rodrigo JP, García-Velasco F, Ambrosch P, Vander Poorten V, Suárez C, Coca-Pelaz A, Strojan P, Hutcheson K, Folz BJ, Bernal-Sprekelsen M, Rinaldo A, Silver CE, Ferlito A.

Head Neck. 2019 Jun;41(6):1816-1823. doi: 10.1002/hed.25616. Epub 2019 Jan 12.

PMID:
30636186
9.

Radiotherapy for parapharyngeal space tumors.

Mendenhall WM, Strojan P, Beitler JJ, Langendijk JA, Suarez C, Lee AW, Rinaldo A, Rodrigo JP, Smee R, Eisbruch A, Harrison LB, Corry J, Ferlito A.

Am J Otolaryngol. 2019 Mar - Apr;40(2):289-291. doi: 10.1016/j.amjoto.2018.12.010. Epub 2018 Dec 21. Review.

PMID:
30621929
10.

Contemporary management of primary parapharyngeal space tumors.

López F, Suárez C, Vander Poorten V, Mäkitie A, Nixon IJ, Strojan P, Hanna EY, Rodrigo JP, de Bree R, Quer M, Takes RP, Bradford CR, Shaha AR, Sanabria A, Rinaldo A, Ferlito A.

Head Neck. 2019 Feb;41(2):522-535. doi: 10.1002/hed.25439. Epub 2018 Dec 14. Review.

PMID:
30549361
11.

Correlation of focal adhesion kinase expression with nodal metastasis in patients with head and neck cutaneous squamous cell carcinoma.

Munguía-Calzada P, Fernández-Vega I, Martínez-Camblor P, Díaz-Coto S, García-Pedrero JM, Vivanco B, Osuna CG, Vazquez-Lopez F, Rodrigo JP, Santos-Juanes J.

Head Neck. 2019 May;41(5):1290-1296. doi: 10.1002/hed.25556. Epub 2018 Dec 10.

PMID:
30537291
12.

Carotid blowout syndrome: modern trends in management.

Suárez C, Fernández-Alvarez V, Hamoir M, Mendenhall WM, Strojan P, Quer M, Silver CE, Rodrigo JP, Rinaldo A, Ferlito A.

Cancer Manag Res. 2018 Nov 13;10:5617-5628. doi: 10.2147/CMAR.S180164. eCollection 2018. Review.

13.

Distinctive Expression and Amplification of Genes at 11q13 in Relation to HPV Status with Impact on Survival in Head and Neck Cancer Patients.

Hermida-Prado F, Menéndez ST, Albornoz-Afanasiev P, Granda-Diaz R, Álvarez-Teijeiro S, Villaronga MÁ, Allonca E, Alonso-Durán L, León X, Alemany L, Mena M, Del-Rio-Ibisate N, Astudillo A, Rodríguez R, Rodrigo JP, García-Pedrero JM.

J Clin Med. 2018 Dec 1;7(12). pii: E501. doi: 10.3390/jcm7120501.

14.

PD-L1 Expression in Tumor Cells Is an Independent Unfavorable Prognostic Factor in Oral Squamous Cell Carcinoma.

de Vicente JC, Rodríguez-Santamarta T, Rodrigo JP, Blanco-Lorenzo V, Allonca E, García-Pedrero JM.

Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):546-554. doi: 10.1158/1055-9965.EPI-18-0779. Epub 2018 Nov 28.

PMID:
30487133
15.

Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets.

Álvarez-Teijeiro S, García-Inclán C, Villaronga MÁ, Casado P, Hermida-Prado F, Granda-Díaz R, Rodrigo JP, Calvo F, Del-Río-Ibisate N, Gandarillas A, Morís F, Hermsen M, Cutillas P, García-Pedrero JM.

Cancers (Basel). 2018 Sep 17;10(9). pii: E334. doi: 10.3390/cancers10090334.

16.

Molecular and health effects in the upper respiratory tract associated with tobacco smoking other than cigarettes.

Szyfter K, Napierala M, Florek E, Braakhuis BJM, Takes RP, Rodrigo JP, Rinaldo A, Silver CE, Ferlito A.

Int J Cancer. 2019 Jun 1;144(11):2635-2643. doi: 10.1002/ijc.31846. Epub 2018 Oct 4. Review.

PMID:
30183075
17.

Surgical margins in head and neck cancer: Intra- and postoperative considerations.

Thomas Robbins K, Triantafyllou A, Suárez C, López F, Hunt JL, Strojan P, Williams MD, Braakhuis BJM, de Bree R, Hinni ML, Kowalski LP, Rinaldo A, Rodrigo JP, Vander Poorten V, Nixon IJ, Takes RP, Silver CE, Ferlito A.

Auris Nasus Larynx. 2019 Feb;46(1):10-17. doi: 10.1016/j.anl.2018.08.011. Epub 2018 Aug 30. Review.

PMID:
30172560
18.

The Current Role of Salvage Surgery in Recurrent Head and Neck Squamous Cell Carcinoma.

Hamoir M, Schmitz S, Suarez C, Strojan P, Hutcheson KA, Rodrigo JP, Mendenhall WM, Simo R, Saba NF, D'Cruz AK, Haigentz M Jr, Bradford CR, Genden EM, Rinaldo A, Ferlito A.

Cancers (Basel). 2018 Aug 10;10(8). pii: E267. doi: 10.3390/cancers10080267. Review.

19.

Prognosis of subglottic carcinoma: Is it really worse?

Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A.

Head Neck. 2019 Feb;41(2):511-521. doi: 10.1002/hed.25172. Epub 2018 Jun 26. Review.

PMID:
29947111
20.

Reply to: "Prognostic significance of tumor budding in cutaneous squamous cell carcinoma".

Santos-Juanes J, Rodrigo JP, Gonzalez-Guerrero M, Martínez-Camblor P.

J Am Acad Dermatol. 2018 Jul;79(1):e7. doi: 10.1016/j.jaad.2017.08.048. No abstract available.

PMID:
29908824
21.

Management of differentiated thyroid carcinomas.

Fernández-Vañes L, Llorente JL, García-Cabo P, Menéndez M, Pedregal D, Rodrigo JP, López F.

Acta Otorrinolaringol Esp. 2018 Jun 4. pii: S0001-6519(18)30081-5. doi: 10.1016/j.otorri.2018.03.002. [Epub ahead of print] English, Spanish.

PMID:
29880224
22.

Oncological and functional outcomes of transoral laser surgery for laryngeal carcinoma.

Pedregal-Mallo D, Sánchez Canteli M, López F, Álvarez-Marcos C, Llorente JL, Rodrigo JP.

Eur Arch Otorhinolaryngol. 2018 Aug;275(8):2071-2077. doi: 10.1007/s00405-018-5027-z. Epub 2018 Jun 5.

PMID:
29869708
23.

Management of severe and/or refractory epistaxis.

García-Cabo P, Fernández-Vañes L, Pedregal D, Menéndez Del Castro M, Murias E, Vega P, Llorente JL, Rodrigo JP, López F.

Acta Otorrinolaringol Esp. 2018 May 18. pii: S0001-6519(18)30068-2. doi: 10.1016/j.otorri.2018.02.004. [Epub ahead of print] English, Spanish.

PMID:
29784243
24.

Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma.

Manterola L, Aguirre P, Larrea E, Arestín M, Gaafar A, Elorriaga K, Goicoechea I, Armesto M, Fernández-Mercado M, Zabalza I, López-Duque JC, Larruskain E, Sistiaga JA, Landa M, Zabala A, Santaolalla F, Municio JA, Ispizua Á, García-Pedrero JM, Rodrigo JP, Lawrie CH.

Sci Rep. 2018 Apr 26;8(1):6613. doi: 10.1038/s41598-018-24780-7.

25.

Overcoming wound complications in head and neck salvage surgery.

Kwon D, Genden EM, de Bree R, Rodrigo JP, Rinaldo A, Sanabria A, Rapidis AD, Takes RP, Ferlito A.

Auris Nasus Larynx. 2018 Dec;45(6):1135-1142. doi: 10.1016/j.anl.2018.03.008. Review.

PMID:
29692326
26.

Immunohistochemical Expression of Cortactin and Focal Adhesion Kinase Predicts Recurrence Risk and Laryngeal Cancer Risk Beyond Histologic Grading.

Villaronga MÁ, Hermida-Prado F, Granda-Díaz R, Menéndez ST, Álvarez-Teijeiro S, Quer M, Vilaseca I, Allonca E, Garzón-Arango M, Sanz-Moreno V, Astudillo A, Rodrigo JP, García-Pedrero JM.

Cancer Epidemiol Biomarkers Prev. 2018 Jul;27(7):805-813. doi: 10.1158/1055-9965.EPI-17-1082. Epub 2018 Apr 13.

PMID:
29654156
27.

Understanding Interactions of Smoking on Prognosis of HPV-Associated Oropharyngeal Cancers.

Haigentz M Jr, Suarez C, Strojan P, Rodrigo JP, Rinaldo A, Bradford CR, Corry J, Takes RP, Ferlito A.

Adv Ther. 2018 Mar;35(3):255-260. doi: 10.1007/s12325-018-0682-4. Epub 2018 Mar 6.

PMID:
29511982
28.

Sacrifice and extracranial reconstruction of the common or internal carotid artery in advanced head and neck carcinoma: Review and meta-analysis.

Bäck LJJ, Aro K, Tapiovaara L, Vikatmaa P, de Bree R, Fernández-Álvarez V, Kowalski LP, Nixon IJ, Rinaldo A, Rodrigo JP, Robbins KT, Silver CE, Snyderman CH, Suárez C, Takes RP, Ferlito A.

Head Neck. 2018 Jun;40(6):1305-1320. doi: 10.1002/hed.25093. Epub 2018 Feb 5.

PMID:
29405536
29.

Selective neck dissection in surgically treated head and neck squamous cell carcinoma patients with a clinically positive neck: Systematic review.

Rodrigo JP, Grilli G, Shah JP, Medina JE, Robbins KT, Takes RP, Hamoir M, Kowalski LP, Suárez C, López F, Quer M, Boedeker CC, de Bree R, Coskun H, Rinaldo A, Silver CE, Ferlito A.

Eur J Surg Oncol. 2018 Apr;44(4):395-403. doi: 10.1016/j.ejso.2018.01.003. Epub 2018 Jan 11. Review.

PMID:
29395434
30.

Prognostic value of lymph node ratio in head and neck squamous cell carcinoma.

Talmi YP, Takes RP, Alon EE, Nixon IJ, López F, de Bree R, Rodrigo JP, Shaha AR, Halmos GB, Rinaldo A, Ferlito A.

Head Neck. 2018 May;40(5):1082-1090. doi: 10.1002/hed.25080. Epub 2018 Feb 2. Review.

PMID:
29394461
31.

Dysregulation of Mir-196b in Head and Neck Cancers Leads to Pleiotropic Effects in the Tumor Cells and Surrounding Stromal Fibroblasts.

Álvarez-Teijeiro S, Menéndez ST, Villaronga MÁ, Rodrigo JP, Manterola L, de Villalaín L, de Vicente JC, Alonso-Durán L, Fernández MP, Lawrie CH, García-Pedrero JM.

Sci Rep. 2017 Dec 19;7(1):17785. doi: 10.1038/s41598-017-18138-8.

32.

FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.

Tornin J, Hermida-Prado F, Padda RS, Gonzalez MV, Alvarez-Fernandez C, Rey V, Martinez-Cruzado L, Estupiñan O, Menendez ST, Fernandez-Nevado L, Astudillo A, Rodrigo JP, Lucien F, Kim Y, Leong HS, Garcia-Pedrero JM, Rodriguez R.

Neoplasia. 2018 Jan;20(1):44-56. doi: 10.1016/j.neo.2017.11.004. Epub 2017 Nov 28.

33.

The central compartment - Center of controversy, confusion, and concern in management of differentiated thyroid cancer.

Shaha AR, Silver CE, Angelos P, Nixon IJ, Rodrigo JP, Sanabria A, Vander Poorten V, Williams MD, Rinaldo A, Ferlito A.

Eur J Surg Oncol. 2017 Nov;43(11):1981-1984. doi: 10.1016/j.ejso.2017.08.001. Epub 2017 Aug 12. No abstract available.

PMID:
28916416
34.

A Novel Role For Nanog As An Early Cancer Risk Marker In Patients With Laryngeal Precancerous Lesions.

Rodrigo JP, Villaronga MÁ, Menéndez ST, Hermida-Prado F, Quer M, Vilaseca I, Allonca E, Pedregal Mallo D, Astudillo A, García-Pedrero JM.

Sci Rep. 2017 Sep 11;7(1):11110. doi: 10.1038/s41598-017-11709-9.

35.

Response assessment after induction chemotherapy for head and neck squamous cell carcinoma: From physical examination to modern imaging techniques and beyond.

de Bree R, Wolf GT, de Keizer B, Nixon IJ, Hartl DM, Forastiere AA, Haigentz M Jr, Rinaldo A, Rodrigo JP, Saba NF, Suárez C, Vermorken JB, Ferlito A.

Head Neck. 2017 Nov;39(11):2329-2349. doi: 10.1002/hed.24883. Epub 2017 Aug 17. Review.

36.

Prognostic significance of E-cadherin and β-catenin expression in HPV-negative oropharyngeal squamous cell carcinomas.

García-Pedrero JM, García-Cabo P, Ángeles Villaronga M, Hermida-Prado F, Granda-Díaz R, Allonca E, Rodrigo JP.

Head Neck. 2017 Nov;39(11):2293-2300. doi: 10.1002/hed.24897. Epub 2017 Aug 17.

PMID:
28815780
37.

Annexin A1 down-regulation in head and neck squamous cell carcinoma is mediated via transcriptional control with direct involvement of miR-196a/b.

Álvarez-Teijeiro S, Menéndez ST, Villaronga MÁ, Pena-Alonso E, Rodrigo JP, Morgan RO, Granda-Díaz R, Salom C, Fernandez MP, García-Pedrero JM.

Sci Rep. 2017 Jul 28;7(1):6790. doi: 10.1038/s41598-017-07169-w.

38.

Tumor programmed cell death ligand 1 expression correlates with nodal metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.

García-Pedrero JM, Martínez-Camblor P, Diaz-Coto S, Munguia-Calzada P, Vallina-Alvarez A, Vazquez-Lopez F, Rodrigo JP, Santos-Juanes J.

J Am Acad Dermatol. 2017 Sep;77(3):527-533. doi: 10.1016/j.jaad.2017.05.047. Epub 2017 Jul 14.

PMID:
28716437
39.

Phosphorylated ribosomal protein S6 correlation with p21 expression and inverse association with tumor size in oral squamous cell carcinoma.

de Vicente JC, Peña I, Rodrigo JP, Rodríguez-Santamarta T, Lequerica-Fernández P, Suárez-Fernández L, Allonca E, García-Pedrero JM.

Head Neck. 2017 Sep;39(9):1876-1887. doi: 10.1002/hed.24854. Epub 2017 Jul 4.

PMID:
28675642
40.

Multidisciplinary management of head and neck cancer: First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer (part 1).

Mañós M, Giralt J, Rueda A, Cabrera J, Martinez-Trufero J, Marruecos J, Lopez-Pousa A, Rodrigo JP, Castelo B, Martínez-Galán J, Arias F, Chaves M, Herranz JJ, Arrazubi V, Baste N, Castro A, Mesía R.

Oral Oncol. 2017 Jul;70:58-64. doi: 10.1016/j.oraloncology.2017.04.004. Epub 2017 Apr 17. Review.

41.

How phenotype guides management of non-conventional squamous cell carcinomas of the larynx?

López F, Williams MD, Cardesa A, Hunt JL, Strojan P, Rinaldo A, Nixon IJ, Rodrigo JP, Saba NF, Mendenhall WM, Quer M, Suárez C, Ferlito A.

Eur Arch Otorhinolaryngol. 2017 Jul;274(7):2709-2726. doi: 10.1007/s00405-017-4533-8. Epub 2017 Mar 31. Review.

PMID:
28364287
42.

Ethical issues in non-intervention trials for thyroid cancer.

Angelos P, Hartl DM, Shah JP, Nixon IJ, Owen RP, Rinaldo A, Rodrigo JP, Shaha AR, Silver CE, Suárez C, Ferlito A.

Eur J Surg Oncol. 2018 Mar;44(3):316-320. doi: 10.1016/j.ejso.2017.03.002. Epub 2017 Mar 16.

PMID:
28343732
43.

The adverse prognostic effect of tumor budding on the evolution of cutaneous head and neck squamous cell carcinoma.

Gonzalez-Guerrero M, Martínez-Camblor P, Vivanco B, Fernández-Vega I, Munguía-Calzada P, Gonzalez-Gutierrez MP, Rodrigo JP, Galache C, Santos-Juanes J.

J Am Acad Dermatol. 2017 Jun;76(6):1139-1145. doi: 10.1016/j.jaad.2017.01.015. Epub 2017 Mar 14.

PMID:
28314684
44.

How Phenotype Guides Management of the Most Common Malignant Salivary Neoplasms of the Larynx?

López F, Williams MD, Skálová A, Hellquist H, Suárez C, Nixon IJ, Rodrigo JP, Cardesa A, Strojan P, Quer M, Hunt JL, Rinaldo A, Ferlito A.

Adv Ther. 2017 Apr;34(4):813-825. doi: 10.1007/s12325-017-0494-y. Epub 2017 Feb 21. Review.

PMID:
28224460
45.

Results of total laryngectomy as treatment for locally advanced hypopharyngeal cancer.

García-Cabo Herrero P, Fernández-Vañes L, López Álvarez F, Álvarez Marcos C, Llorente JL, Rodrigo JP.

Acta Otorrinolaringol Esp. 2017 Nov - Dec;68(6):328-335. doi: 10.1016/j.otorri.2016.11.001. Epub 2017 Jan 19. English, Spanish.

46.

Clinically relevant HIF-1α-dependent metabolic reprogramming in oropharyngeal squamous cell carcinomas includes coordinated activation of CAIX and the miR-210/ISCU signaling axis, but not MCT1 and MCT4 upregulation.

Sáenz-de-Santa-María I, Bernardo-Castiñeira C, Secades P, Bernaldo-de-Quirós S, Rodrigo JP, Astudillo A, Chiara MD.

Oncotarget. 2017 Feb 21;8(8):13730-13746. doi: 10.18632/oncotarget.14629.

47.

Histological analysis of tonsillectomies: relationship with surgical technique, post-operative pain and haemorrhage.

Magdalena ML, Solé A, Blanco V, Rodrigo JP.

J Laryngol Otol. 2016 Dec;130(12):1142-1146. Epub 2016 Nov 10.

PMID:
27830635
48.

Removing the Taboo on the Surgical Violation (Cut-Through) of Cancer.

Robbins KT, Bradford CR, Rodrigo JP, Suárez C, de Bree R, Kowalski LP, Rinaldo A, Silver CE, Lund VJ, Nibu KI, Ferlito A.

JAMA Otolaryngol Head Neck Surg. 2016 Oct 1;142(10):1010-1013. doi: 10.1001/jamaoto.2016.1826. Review.

PMID:
27468162
49.

HERG1 potassium channel expression in potentially malignant disorders of the oral mucosa and prognostic relevance in oral squamous cell carcinoma.

Fernández-Valle Á, Rodrigo JP, Rodríguez-Santamarta T, Villaronga MÁ, Álvarez-Teijeiro S, García-Pedrero JM, Suárez-Fernández L, Lequerica-Fernández P, de Vicente JC.

Head Neck. 2016 Nov;38(11):1672-1678. doi: 10.1002/hed.24493. Epub 2016 Apr 30.

PMID:
27131339
50.

The impact of family history on non-medullary thyroid cancer.

Nixon IJ, Suárez C, Simo R, Sanabria A, Angelos P, Rinaldo A, Rodrigo JP, Kowalski LP, Hartl DM, Hinni ML, Shah JP, Ferlito A.

Eur J Surg Oncol. 2016 Oct;42(10):1455-63. doi: 10.1016/j.ejso.2016.08.006. Epub 2016 Aug 11. Review.

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